Diphenhydramine combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 6/30/2004 53 9/12/2005 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal 12/18/2004 38 9/12/2005 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Other Serious 49 Female 1/19/2006 Physician United States
Primary
Concomitant
Vomiting 10/8/2005 61 Female 1/5/2006 Consumer United States
Primary
Concomitant
Pruritus 11/7/2005 85 Male 141 lb 11/9/2005 United States
Primary
Concomitant
Urticaria Other Serious 2/23/2006 55 Male 228 lb 4/14/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 8/28/2007 51 Female 207 lb 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Respiratory Acidosis Other Serious 9/1/2007 54 Male 212 lb 11/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Product Quality Issue Other Serious 9/27/2009 52 Male 201 lb 10/7/2009 United States
Primary
Concomitant
Femoral Arterial Stenosis Hospitalization 8/13/2009 60 Female 136 lb 1/6/2010 Other Health Professional United States
Primary
Concomitant
Blood Bilirubin Increased 10/21/2009 77 Male 161 lb 1/13/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 7/1/2007 Female 135 lb 1/18/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 1/11/2010 United States
Primary
Concomitant
Thrombosis In Device Death 3/6/2008 Female 220 lb 1/25/2010 Physician United States
Primary
Secondary
Concomitant
Thrombosis In Device Death 3/6/2008 Female 220 lb 1/26/2010 Physician United States
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 3/12/2007 Female 120 lb 2/1/2010 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 3/12/2007 Female 120 lb 2/10/2010 Lawyer United States
Primary
Concomitant
Sepsis Other Serious 10/1/2009 60 Female 4/26/2010 Consumer United States
Primary
Secondary
Procedural Pain Other Serious 10/1/2009 60 Female 4/21/2010 United States
Primary
Secondary
Pain In Extremity Other Serious 60 Female 4/28/2010 Consumer United States
Primary
Secondary
Sudden Death 4/28/2010 62 Male 209 lb 4/28/2010 United States
Primary
Concomitant
Gastric Ulcer Hospitalization 4/23/2010 61 Female 199 lb 5/4/2010 Physician United States
Primary
Secondary
Concomitant
Vasodilatation Other Serious 1/1/2007 65 Male 121 lb 5/5/2010 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 4/14/2010 79 Female 145 lb 5/7/2010 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Rash Generalised Other Serious 1/9/2008 39 Female 134 lb 5/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/12/2008 75 Male 6/28/2010 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 57 Female 211 lb 6/28/2010 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 6/30/2010 Physician United States
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 60 Female 6/23/2010 Consumer United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 7/1/2007 52 Female 135 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Somnolence Other Serious 6/1/2010 69 Female 100 lb 7/12/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/16/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/17/2010 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Thrombophlebitis Superficial Hospitalization 4/23/2010 61 Female 196 lb 8/4/2010 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 7/28/2010 Other Health Professional United States
Primary
Concomitant
Dyspnoea Hospitalization 5/10/2010 81 Male 256 lb 7/30/2010 Physician United States
Primary
Secondary
Concomitant
Pancytopenia Life Threatening 8/2/2010 86 Female 133 lb 8/16/2010 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 8/23/2010 Other Health Professional United States
Primary
Concomitant
Proteinuria Other Serious 9/9/2009 64 Female 152 lb 8/24/2010 Other Health Professional United States
Primary
Concomitant
Gastric Ulcer Hospitalization 4/23/2010 61 Female 196 lb 8/25/2010 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 1/10/2008 75 Male 181 lb 8/26/2010 Lawyer United States
Primary
Concomitant
Visual Impairment 1/1/2010 90 Female 101 lb 9/1/2010 Physician United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/5/2007 39 Female 134 lb 10/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Respiratory Acidosis Other Serious 9/1/2007 54 Male 212 lb 10/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Extremity 60 Female 11/11/2010 Consumer United States
Primary
Secondary
Scratch Life Threatening 11/10/2010 71 Male 190 lb 11/12/2010 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/1/2006 64 Male 11/24/2010 Other Health Professional United States
Primary
Concomitant
Transplant Rejection Hospitalization 11/22/2010 66 Female 201 lb 12/10/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Other Serious 11/3/2010 62 Female 130 lb 12/14/2010 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/15/2008 60 Male 12/15/2010 Other Health Professional United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/14/2010 66 Male 1/17/2011 Other Health Professional United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2007 65 Male 1/17/2011 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 12/14/2010 66 Male 1/20/2011 Other Health Professional United States
Primary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 1/26/2011 Lawyer United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 1/1/2007 65 Male 1/27/2011 Other Health Professional United States
Primary
Concomitant
Blister 7/5/2009 48 Male 270 lb 1/29/2011 United States
Primary
Concomitant
Hyperkalaemia Hospitalization 11/22/2010 66 Female 201 lb 1/31/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Other Serious 4/1/2008 31 Female 284 lb 2/3/2011 Lawyer United States
Primary
Concomitant
Generalised Oedema Hospitalization 5/9/1997 37 Female 193 lb 2/21/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tendonitis Hospitalization 5/9/1997 37 Female 193 lb 3/1/2011 United States
Primary
Secondary
Concomitant
Asthma Other Serious 4/1/2008 31 Female 284 lb 3/23/2011 Other Health Professional United States
Primary
Concomitant
Groin Pain Other Serious 5/9/1997 37 Female 193 lb 3/24/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Obstruction Other Serious 4/14/2010 79 Female 145 lb 3/25/2011 Consumer United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 5/9/1997 37 Female 193 lb 5/9/2011 Physician United States
Primary
Secondary
Concomitant
Seasonal Affective Disorder Other Serious 1/1/2010 66 Female 225 lb 11/4/2011 Consumer United States
Primary
Concomitant
Serotonin Syndrome Death 1/1/2011 75 Female 226 lb 3/22/2012 Pharmacist United States
Primary
Secondary
Concomitant
Interacting
Serotonin Syndrome Death 1/1/2011 75 Female 226 lb 3/27/2012 Pharmacist United States
Primary
Concomitant
Interacting
Drug Interaction Death 1/1/2011 75 Female 226 lb 4/24/2012 Pharmacist United States
Primary
Concomitant
Interacting
Hyperthermia Malignant Death 1/1/2011 75 Female 235 lb 4/25/2012 Physician United States
Primary
Concomitant
Interacting
Serotonin Syndrome Death 1/1/2011 75 Female 235 lb 5/3/2012 Consumer United States
Primary
Concomitant
Interacting
Serotonin Syndrome Death 1/1/2011 75 Female 226 lb 5/10/2012 Pharmacist United States
Primary
Concomitant
Interacting
Coronary Artery Thrombosis Other Serious 68 Male 6/1/2012 Physician United States
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 68 Male 7/10/2012 Physician United States
Primary
Concomitant
Coronary Artery Thrombosis Other Serious 68 Male 7/19/2012 Physician United States
Primary
Concomitant
Urinary Tract Infection Staphylococcal Hospitalization 1/19/2011 67 Male 207 lb 10/25/2012 Physician Us
Primary
Concomitant
Convulsion Hospitalization 3/2010 64 Female 10/29/2012 Consumer Us
Primary
Concomitant
Overdose Hospitalization 49 Male 9/11/2012 Other Health Professional Us
Primary
Secondary
Overdose Death 49 Male 9/10/2013 Other Health Professional Us
Primary
Secondary
Tardive Dyskinesia Other Serious Female 143 lb 9/25/2012 Lawyer Us
Primary
Concomitant
Traumatic Haemorrhage Hospitalization 2011 62 Female 165 lb 9/26/2012 Physician Us
Primary
Secondary
Concomitant
Tremor Other Serious Female 138 lb 9/17/2012 Lawyer Us
Primary
Concomitant
Thrombocytopenia Hospitalization 7/6/2012 68 Male 202 lb 12/31/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/12/2012 32 Female 289 lb 9/6/2012 Consumer Us
Primary
Secondary
Concomitant
Peritonsillar Abscess Hospitalization 8/11/2012 72 Female 143 lb 11/15/2013 Physician Us
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 4/2011 Female 9/5/2012 Consumer Us
Primary
Concomitant
Renal Tubular Necrosis Hospitalization 8/2012 Male 229 lb 9/14/2012 Physician Us
Primary
Secondary
Concomitant
Pyrexia Other Serious 5/22/2012 66 Female 182 lb 9/17/2012 Consumer Us
Primary
Concomitant
Coma Death 9/19/2012 69 Male 247 lb 9/20/2012 Other Health Professional Us
Concomitant
Rash 7/6/2012 64 Female 204 lb 8/10/2012 Pharmacist Us
Primary
Concomitant
Ventricular Tachycardia Death 10/4/2012 59 Male 205 lb 11/20/2012 Consumer Us
Primary
Concomitant
Surgery Death 11/5/2012 Other Health Professional De
Primary
Secondary
Atrial Fibrillation Hospitalization 11/7/2012 Male 237 lb 11/20/2013 Physician Us
Primary
Secondary
Concomitant
Wound Infection Hospitalization Female 137 lb 12/20/2012 Physician Us
Primary
Concomitant
Mental Status Changes Death 9/19/2012 69 Male 247 lb 12/16/2012 Registered Nurse Us
Primary
Concomitant
Urticaria Other Serious 11/20/2012 Male 176 lb 12/17/2012 Pharmacist Us
Primary
Concomitant
Toxicity To Various Agents Death Male 1/7/2013 Other Health Professional Us
Primary
Secondary
Respiratory Arrest Death 2011 60 Male 1/8/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death 60 Male 1/21/2013 Physician Us
Primary
Secondary
Drug Level Increased Death 53 Female 1/28/2013 Other Health Professional Us
Primary
Secondary
Hospitalisation Hospitalization Male 2/6/2013 Other Health Professional Us
Primary
Concomitant
Completed Suicide Death 60 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 38 Male 1/29/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 60 Male 1/29/2013 Other Health Professional Us
Primary
Secondary
Gastrooesophageal Reflux Disease Hospitalization 10/12/2010 64 Male 209 lb 2/26/2013 Physician Us
Primary
Concomitant
Respiratory Arrest Death 60 Male 2/18/2013 Physician Us
Primary
Secondary
Hypomagnesaemia Hospitalization 2/11/2013 17 Female 135 lb 3/7/2013 Physician Us
Primary
Secondary
Concomitant
Completed Suicide Death 38 Male 2/8/2013 Other Health Professional Us
Primary
Secondary
Toxicity To Various Agents Death Male 3/4/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 2011 38 Male 2/4/2013 Physician Us
Primary
Secondary
Drug Abuse Death 2011 53 Female 2/4/2013 Physician Us
Primary
Secondary
Death Death Male 3/7/2013 Other Health Professional Us
Primary
Secondary
Completed Suicide Death 2011 60 Male 2/4/2013 Physician Us
Primary
Secondary
Death Death Male 3/7/2013 Physician Us
Primary
Secondary
Death Other Serious Male 3/10/2013 Physician Us
Primary
Secondary
Toxicity To Various Agents Death Male 3/6/2013 Us
Primary
Secondary
Toxicity To Various Agents Death Male 3/5/2013 Physician Us
Primary
Secondary
Troponin Increased Other Serious 3/2013 51 Male 151 lb 5/21/2013 Pharmacist Ca
Primary
Concomitant
Toxicity To Various Agents Death Male 3/15/2013 Other Health Professional Us
Primary
Secondary
Death Death 19 Male Physician Us
Primary
Secondary
Anaphylactic Reaction Life Threatening 2/22/2012 58 Male 3/22/2013 Pharmacist Us
Primary
Secondary
Concomitant
Drug Abuse Death Male 3/13/2013 Other Health Professional Us
Primary
Secondary
Myocardial Infarction Hospitalization 10/13/2010 64 Male 5/16/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Intentional Drug Misuse Death Male 5/31/2013 Other Health Professional Us
Primary
Secondary
Cytomegalovirus Infection Other Serious 4/24/2013 55 Male 238 lb 8/27/2013 Physician Us
Primary
Secondary
Concomitant
Cellulitis Hospitalization 4/19/2013 66 Female 93 lb 9/11/2013 Physician Us
Primary
Secondary
Concomitant
Graft Versus Host Disease In Skin Hospitalization 5/7/2013 56 Male 238 lb 7/23/2013 Physician Us
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 7/20/2013 78 Male 235 lb 7/26/2013 Pharmacist Us
Primary
Concomitant
Nodal Rhythm Death 8/5/2013 66 Female 165 lb 8/6/2013 Pharmacist Us
Concomitant
Suicide Attempt Hospitalization 56 Male 9/6/2013 Pharmacist Us
Primary
Secondary
Suicide Attempt Hospitalization 56 Male 9/9/2013 Other Health Professional Us
Primary
Secondary
Suicide Attempt Hospitalization 56 Male 9/9/2013 Pharmacist Us
Primary
Secondary
Suicide Attempt Hospitalization 56 Male 9/4/2013 Pharmacist Us
Primary
Secondary
Localised Infection Hospitalization 11/2012 76 Male 195 lb 11/26/2012 Pharmacist Us
Primary
Concomitant
Stridor Life Threatening 8/20/2013 50 Female 172 lb 9/9/2013 Pharmacist Us
Primary
Concomitant
Suicide Attempt Life Threatening 56 Male 9/10/2013 Other Health Professional Us
Primary
Secondary
Suicide Attempt Other Serious 56 Male 9/11/2013 Physician Us
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/11/2011 76 Male 168 lb 9/16/2013 Us
Primary
Concomitant
Suicide Attempt Hospitalization 56 Male 9/18/2013 Pharmacist Us
Primary
Secondary
International Normalised Ratio Increased Hospitalization 6/1/2011 65 Male 176 lb 9/25/2013 Pharmacist Us
Primary
Concomitant
Myalgia Required Intervention 6/10/2011 78 Female 158 lb 9/25/2013 Pharmacist Us
Primary
Concomitant
Wound Secretion Other Serious 2003 60 Male 381 lb 4/1/2013 Consumer Us
Primary
Concomitant
Wheezing Other Serious 8/4/2008 49 Female 193 lb 10/1/2013 Consumer Us
Primary
Secondary
Concomitant
Wound Infection Pseudomonas Other Serious 1/23/2006 66 Female 8/16/2013 Consumer Us
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 6/15/2009 68 Male 10/18/2013 Consumer Us
Primary
Concomitant
Weight Decreased Hospitalization 2008 62 Male 160 lb 10/7/2013 Consumer Us
Primary
Concomitant

Drug Data