Diphenhydramine Hcl combined with Ranitidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Erythema Other Serious 1/28/2005 24 Female 269 lb 2/6/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Hospitalization 57 Male 225 lb 3/6/2006 Pharmacist United States
Primary
Concomitant
Weight Fluctuation Other Serious 61 Female 202 lb 3/15/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/1959 14 Female 202 lb 4/5/2006 United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/29/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/17/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/19/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 62 Female 4/28/2006 Physician Hungary
Primary
Concomitant
Pleural Effusion Life Threatening 1/27/2006 45 Female 5/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonitis Death 62 Female 6/21/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Angioneurotic Oedema Required Intervention 6/6/2006 64 Male 121 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/25/2006 60 Male 198 lb 6/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 43 Female 9/11/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 9/13/2006 56 Male 154 lb 9/21/2006 Pharmacist United States
Primary
Concomitant
Hypersensitivity Life Threatening 9/28/2006 62 Male 97 lb 10/16/2006 Other Health Professional Japan
Primary
Concomitant
Septic Shock Other Serious 9/28/2006 62 Male 97 lb 11/8/2006 Consumer Japan
Primary
Concomitant
Septic Shock Other Serious 9/28/2006 62 Male 97 lb 11/9/2006 Consumer Japan
Primary
Concomitant
Respiratory Rate Increased Hospitalization 4/21/2006 51 Female 11/14/2006 Other Health Professional United States
Primary
Secondary
Sputum Purulent Death 1/1/2004 77 Male 121 lb 11/30/2006 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 71 Male 12/11/2006 Other Health Professional Japan
Primary
Concomitant
Venoocclusive Disease Other Serious 10/14/2006 11 Female 60 lb 11/30/2006 Physician Canada
Primary
Concomitant
Splenomegaly Required Intervention 12/3/2006 9 Female 64 lb 12/14/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 1/2/2007 Consumer United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 10/14/2006 11 Female 60 lb 1/4/2007 Physician Canada
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/27/2006 Female 243 lb 12/27/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Sepsis Other Serious 2/14/2005 66 Male 1/16/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 12/27/2006 Female 243 lb 1/17/2007 United States
Primary
Secondary
Concomitant
Pulse Absent Hospitalization 6/1/2006 66 Male 172 lb 1/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 1/25/2007 Consumer United States
Primary
Concomitant
Angioedema Other Serious 11/16/2006 81 Male 106 lb 11/16/2006 Pharmacist United States
Primary
Concomitant
Swelling Face Other Serious 11/16/2006 81 Male 106 lb 11/16/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 200 lb 2/2/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 9/1/2006 74 Male 200 lb 2/6/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 77 Female 98 lb 4/13/2007 Pharmacist United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 6/1/2006 66 Male 172 lb 4/25/2007 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 4/9/2007 19 Male 164 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 164 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/17/2007 69 Male 99 lb 6/6/2007 Other Health Professional Japan
Primary
Concomitant
Ventricular Tachycardia Life Threatening 4/9/2007 19 Male 167 lb 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/17/2007 69 Male 99 lb 6/15/2007 Other Health Professional Japan
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 4/9/2007 19 Male 167 lb 6/7/2007 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 6/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 7/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Pruritus Death 1 Female 7/9/2007
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/3/2007 Consumer Japan
Primary
Secondary
Concomitant
Intestinal Perforation Hospitalization 7/29/2007 Female 8/7/2007 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Hyponatraemia Hospitalization 7/29/2007 Female 8/10/2007 Physician United States
Primary
Secondary
Concomitant
Skin Ulcer Hospitalization 7/29/2007 Female 8/31/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 73 Male 8/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 8/21/2007 Male 9/5/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 9/17/2007 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2004 24 Female 181 lb 9/18/2007 Physician United States
Primary
Concomitant
Lymphopenia Other Serious 9/17/2007 64 Male 185 lb 9/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Interstitial Lung Disease Hospitalization 65 Female 11/8/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 10/28/2007 14 Female 57 lb 12/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Multiple Sclerosis Other Serious 1/1/2003 38 Female 190 lb 1/25/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 2/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 2/8/2008 Physician United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 2/25/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/26/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pulmonary Mass Life Threatening 1/27/2004 17 Female 170 lb 2/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia 3/5/2008 55 Male 180 lb 3/5/2008 Pharmacist United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Hospitalization 7/29/2007 Female 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 11/3/2007 Female 3/20/2008 Physician United States
Primary
Concomitant
Pulse Absent Life Threatening 3/28/2007 79 Male 154 lb 3/28/2008 Pharmacist United States
Primary
Concomitant
Vomiting 33 4/23/2008 Other Health Professional Singapore
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
No Adverse Event 3/21/2008 48 Female 159 lb 5/14/2008 Consumer United States
Primary
Concomitant
Wound Infection Staphylococcal Hospitalization 4/11/2008 Female 117 lb 5/6/2008 United States
Primary
Secondary
Concomitant
Vomiting 33 5/21/2008 Other Health Professional Singapore
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Life Threatening 6/3/2008 Female 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Accident Death 49 Male 7/21/2008 Other Health Professional United States
Primary
Secondary
No Adverse Event 3/21/2008 48 Female 159 lb 8/6/2008 Consumer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Somnolence Other Serious 2/1/2007 Male 492 lb 8/26/2008 Physician United States
Primary
Concomitant
Stomatitis Other Serious Female 8/28/2008 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/7/2008 43 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Mental Status Changes Hospitalization 6/16/2008 Male 9/9/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Vasovagal Hospitalization 7/24/2008 Female 9/17/2008 Physician United States
Primary
Secondary
Concomitant
No Therapeutic Response Other Serious 6/20/2008 Male 9/23/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/10/2008 53 Female 190 lb 10/1/2008 Pharmacist United States
Primary
Concomitant
Death Death 10/3/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Ventricular Tachycardia Required Intervention 4/12/2007 19 Male 165 lb 10/10/2008 Physician United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 33 Female 10/14/2008 Physician United States
Primary
Secondary
Concomitant
Wheezing Required Intervention 9/24/2008 11 Male 66 lb 10/16/2008 Physician Canada
Primary
Concomitant
Respiratory Failure Life Threatening 10/20/2008 69 Male 10/31/2008 Consumer United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 10/19/2008 Male 164 lb 11/4/2008 Physician United States
Primary
Concomitant
Gastroduodenitis Haemorrhagic Hospitalization 10/19/2008 Male 164 lb 11/14/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/12/2007 19 Male 165 lb 11/18/2008 Physician United States
Primary
Secondary
Concomitant
Gastroduodenitis Haemorrhagic Hospitalization 10/19/2008 Male 164 lb 11/26/2008 Physician United States
Primary
Concomitant
Sepsis Death 11/28/2008 72 Female 12/29/2008 Physician Canada
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Transient Ischaemic Attack Hospitalization 1/12/2009 Female 127 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 10/20/2008 69 Male 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Stomatitis Other Serious Female 2/11/2009 Consumer United States
Primary
Concomitant
Mouth Ulceration Other Serious 1/16/2009 Male 243 lb 2/11/2009 United States
Primary
Concomitant
Pleural Effusion Other Serious 2/3/2009 60 Female 2/17/2009 Other Health Professional Austria
Primary
Concomitant
Neck Pain 6/24/2008 18 Male 121 lb 8/11/2008 Pharmacist United States
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 2/3/2009 49 Female 101 lb 3/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 2/3/2009 60 Female 3/5/2009 Other Health Professional Austria
Primary
Concomitant
Cerebral Haemorrhage Hospitalization 2/3/2009 49 Female 101 lb 3/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Required Intervention 9/24/2008 11 Male 66 lb 3/16/2009 Physician Canada
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/30/2005 49 Female 268 lb 4/10/2009 United States
Primary
Concomitant
Wheezing Other Serious 1/17/2005 42 Female 285 lb 4/10/2009 United States
Primary
Concomitant
Potentiating Drug Interaction Death 49 Male 4/15/2009 United States
Primary
Secondary
Suicidal Ideation Other Serious 1/1/2003 36 Male 210 lb 4/21/2009 United States
Primary
Concomitant
Myocardial Ischaemia Hospitalization 3/11/2009 57 Male 4/24/2009 Consumer United States
Primary
Secondary
Concomitant
Wheezing Other Serious 43 Female 170 lb 5/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 6/8/2004 Female 162 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 7/30/2002 37 Male 246 lb 5/14/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2003 38 Female 178 lb 5/20/2009 United States
Primary
Concomitant
Urticaria Hospitalization 5/3/2009 Male 53 lb 5/13/2009 United States
Primary
Secondary
Concomitant
Infection Hospitalization 5/3/2009 Male 53 lb 5/22/2009 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 12/11/2003 23 Female 196 lb 6/15/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/8/2004 Female 162 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 50 Female 7/2/2009
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/1/1998 53 Male 145 lb 7/7/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Hospitalization 5/26/2009 Male 27 lb 6/11/2009 Pharmacist United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 5/5/2009 44 Male 203 lb 7/30/2009 Ireland
Primary
Concomitant
Wound Other Serious 1/1/2004 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 1/4/2007 77 Female 8/14/2009 Spain
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 8/31/2009 Physician United States
Primary
Secondary
Concomitant
Qrs Axis Abnormal Death 6/1/2008 Female 178 lb 9/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2 Female 9/16/2009 Other Health Professional United States
Primary
Concomitant
Subcutaneous Emphysema Hospitalization 5/5/2009 Male 203 lb 9/21/2009 Ireland
Primary
Concomitant
Pancreatitis Other Serious 8/23/2004 48 Female 235 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Tibia Fracture Required Intervention 7/12/2009 61 Male 195 lb 7/13/2009 United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 8/21/2009 51 Female 117 lb 8/27/2009 Pharmacist United States
Primary
Concomitant
Somnolence Life Threatening 8/26/2009 65 Male 8/27/2009 Pharmacist United States
Primary
Concomitant
Pallor Life Threatening 8/10/2009 64 Male 195 lb 8/12/2009 Pharmacist United States
Primary
Concomitant

Drug Data