Diphenhydramine Hcl combined with Paclitaxel

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Erythema Other Serious 1/28/2005 24 Female 269 lb 2/6/2006 Consumer United States
Primary
Concomitant
Metastases To Central Nervous System Life Threatening 3/1/2006 57 Female 3/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/29/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 7/17/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Neutropenia Other Serious 6/19/2003 53 Female 146 lb 2/14/2006 Physician Canada
Primary
Secondary
Concomitant
Respiratory Failure Death 62 Female 4/28/2006 Physician Hungary
Primary
Concomitant
Pneumonitis Death 62 Female 6/21/2006 Other Health Professional Hungary
Primary
Secondary
Concomitant
Hypersensitivity Life Threatening 9/28/2006 62 Male 97 lb 10/16/2006 Other Health Professional Japan
Primary
Concomitant
Death Death 10/6/2006 58 Female 141 lb 10/23/2006 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 10/16/2001 51 Female 10/28/2006 United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 9/3/2006 43 Female 157 lb 10/26/2006 Physician United States
Primary
Secondary
Concomitant
Septic Shock Other Serious 9/28/2006 62 Male 97 lb 11/8/2006 Consumer Japan
Primary
Concomitant
Septic Shock Other Serious 9/28/2006 62 Male 97 lb 11/9/2006 Consumer Japan
Primary
Concomitant
Myocardial Infarction Hospitalization 9/29/1997 66 Male 11/8/2006 Physician United States
Primary
Secondary
Concomitant
Malignant Neoplasm Progression Death 58 Female 141 lb 11/17/2006 Physician United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 11/30/2005 57 Female 12/5/2006 Other Health Professional Japan
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 53 Female 11/23/2006 Japan
Primary
Concomitant
Sputum Purulent Death 1/1/2004 77 Male 121 lb 11/30/2006 Other Health Professional Japan
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 71 Male 12/11/2006 Other Health Professional Japan
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 11/30/2005 53 Female 12/14/2006 Other Health Professional Japan
Primary
Concomitant
Liver Function Test Abnormal 1/31/2006 43 Female 108 lb 2/28/2007 Consumer United States
Primary
Concomitant
Vomiting Life Threatening 3/2/2007 60 Female 3/22/2007 Canada
Primary
Concomitant
Supraventricular Tachycardia Hospitalization 3/16/2007 52 Male 150 lb 4/3/2007 Physician Argentina
Primary
Secondary
Concomitant
Vomiting Other Serious 4/4/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 61 4/5/2007 United States
Primary
Secondary
Concomitant
Sepsis Other Serious 65 4/5/2007 United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 52 4/5/2007 United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 67 4/5/2007 United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 59 NotSpecified 4/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Other Serious 60 4/5/2007 United States
Primary
Secondary
Concomitant
Supraventricular Tachycardia Hospitalization 3/16/2007 52 Male 150 lb 5/18/2007 Physician Argentina
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 4/13/2007 55 Male 145 lb 5/21/2007 Pharmacist United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/17/2007 69 Male 99 lb 6/6/2007 Other Health Professional Japan
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious Female 6/2/2007 Physician Singapore
Primary
Secondary
Concomitant
Oesophageal Stenosis Other Serious Female 6/2/2007 Physician Singapore
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/17/2007 69 Male 99 lb 6/15/2007 Other Health Professional Japan
Primary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 6/26/2007 Consumer Japan
Primary
Secondary
Concomitant
Febrile Neutropenia Life Threatening 1/26/2006 41 Female 137 lb 6/29/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 7/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/3/2007 Consumer Japan
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 5/30/2007 66 Male 148 lb 8/9/2007 Consumer Japan
Primary
Secondary
Concomitant
Vomiting Life Threatening 9/14/2007 79 Female 10/10/2007 Germany
Primary
Concomitant
Vomiting Hospitalization 5/7/2007 69 Female 231 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Life Threatening 9/14/2007 Female 1/25/2008 Physician Germany
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 2/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/14/2008 Physician United States
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 2/25/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Death Death 2/25/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/26/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 2/29/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/15/2008 45 Female 3/12/2008 Physician United States
Primary
Secondary
Concomitant
Small Intestinal Obstruction Hospitalization 1/25/2008 Female 3/13/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/15/2008 Female 95 lb 3/17/2008 Physician United States
Primary
Secondary
Nausea Hospitalization 2/15/2008 45 Female 95 lb 2/29/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/15/2008 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/15/2008 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 3/31/2008 Consumer United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 Female 117 lb 4/10/2008 Physician United States
Primary
Secondary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 Female 117 lb 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 4/2/2008 60 Male 137 lb 4/23/2008 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 3/12/2008 Female 117 lb 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Pericarditis Hospitalization 3/12/2008 Female 117 lb 5/8/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 6/5/2008
Primary
Secondary
Concomitant
Gastric Haemorrhage Life Threatening 6/3/2008 Female 6/19/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Multi-organ Failure Life Threatening 1/1/2007 50 Male 7/2/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Gastric Haemorrhage Life Threatening 6/3/2008 Female 7/2/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Intestinal Prolapse Hospitalization 6/23/2008 Female 140 lb 7/9/2008 Other Health Professional United States
Primary
Concomitant
Uterine Polyp Other Serious 4/25/2008 72 Female 7/10/2008 Japan
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/23/2008 Female 140 lb 8/8/2008 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/24/2008 74 Female 97 lb 9/2/2008 United States
Primary
Secondary
Concomitant
Stomatitis Other Serious Female 8/28/2008 Physician United States
Primary
Concomitant
Mental Status Changes Hospitalization 7/7/2008 43 Female 9/4/2008 Pharmacist United States
Primary
Concomitant
Colitis Ulcerative Hospitalization 8/18/2008 Female 110 lb 9/12/2008 United States
Primary
Secondary
Concomitant
Hypercapnia Hospitalization 11/3/2005 76 Male 119 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Colitis Ulcerative Hospitalization 8/18/2008 56 Female 110 lb 9/24/2008 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 7/10/2008 53 Female 190 lb 10/1/2008 Pharmacist United States
Primary
Concomitant
Death Death 10/3/2008 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Portal Vein Thrombosis Other Serious 9/9/2008 Female 10/9/2008 Consumer United Kingdom
Primary
Secondary
Concomitant
Vasculitis Other Serious 9/29/2008 65 Female 120 lb 10/16/2008 Pharmacist United States
Primary
Concomitant
Vasculitis Other Serious 10/10/2008 56 Female 108 lb 10/16/2008 Pharmacist United States
Primary
Concomitant
Colitis Ulcerative Hospitalization 8/18/2008 Female 110 lb 11/13/2008 United States
Primary
Secondary
Concomitant
Large Intestine Perforation Hospitalization 2/20/2008 60 Female 157 lb 11/18/2008 Consumer United States
Primary
Concomitant
Colitis Ulcerative Hospitalization 8/18/2008 56 Female 110 lb 11/24/2008 Consumer United States
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 5/27/2008 Female 12/11/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Other Serious 11/10/2008 56 Male 193 lb 12/4/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/31/2008
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/5/2009
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 1/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/5/2008 Female 132 lb 1/14/2009 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/12/2009 Female 127 lb 1/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stupor Life Threatening 1/19/2005 56 Female 279 lb 1/15/2009 Physician Mexico
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 2/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Stomatitis Other Serious Female 2/11/2009 Consumer United States
Primary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 2/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 2/10/2009 54 Female 170 lb 3/13/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 11/21/2007 61 Male 4/6/2009 Russian Federation
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious Female 4/17/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pneumonia Life Threatening 3/5/2009 Male 141 lb 4/17/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 56 Female 4/24/2009 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 4/9/2009 79 Female 150 lb 4/27/2009 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Other Serious 4/24/2008 74 Female 97 lb 5/1/2009 United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 5/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 3/5/2009 Male 141 lb 5/7/2009 Physician Taiwan, Province Of China
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/8/2004 Female 162 lb 5/8/2009 Physician United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 5/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tooth Loss Other Serious 1/1/2001 Male 6/5/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 6/8/2004 Female 162 lb 6/19/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2009 Male 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 7/10/2009 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/18/2009 Male 7/14/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hypotension Life Threatening 11/21/2007 61 Male 7/13/2009 Physician Russian Federation
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 1/4/2007 77 Female 8/14/2009 Spain
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 7/9/2009 45 Female 8/11/2009 Physician Indonesia
Primary
Concomitant
Malaise Hospitalization 7/28/2009 Female 8/25/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Colitis Ulcerative Hospitalization 8/18/2008 Female 110 lb 8/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 8/31/2009 Physician United States
Primary
Secondary
Concomitant
Qrs Axis Abnormal Death 6/1/2008 Female 178 lb 9/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 9/28/2009 Physician United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 Female 178 lb 9/30/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Death 10/2/2009 Physician United States
Primary
Concomitant
Urosepsis Death 10/2/2009 Physician United States
Primary
Concomitant
Haemolytic Anaemia Other Serious 63 Female 10/2/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 10/13/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Neoplasm Hospitalization 9/15/2009 Female 10/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Neoplasm Hospitalization 9/15/2009 Female 10/30/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious Male 10/21/2009 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious Female 10/21/2009 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious Female 10/21/2009 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Death 11/11/2009 55 Male 11/23/2009 Consumer United States
Primary
Secondary
Concomitant
Sepsis Death 12/1/2009 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 8/23/2009 Male 12/1/2009 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress 10/29/2009 72 Male 11/27/2009 Pharmacist United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 11/21/2009 66 Female 12/4/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Ischaemic Stroke Death 6/1/2008 61 Female 178 lb 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pallor Other Serious 74 Female 12/8/2009 Other Health Professional Japan
Primary
Concomitant
Osteitis Other Serious 9/12/2008 Female 101 lb 12/9/2009 Physician Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Hospitalization 11/21/2009 66 Female 132 lb 12/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Osteitis Hospitalization 9/22/2008 63 Female 12/10/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Osteitis Other Serious 9/12/2008 Female 101 lb 12/10/2009 Physician Japan
Primary
Secondary
Concomitant
Cerebrovascular Accident Life Threatening 3/14/2009 74 Male 141 lb 12/14/2009 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Proteinuria Hospitalization 9/22/2008 Female 101 lb 12/16/2009 Physician Japan
Primary
Secondary
Concomitant
Neutropenic Sepsis Other Serious 11/21/2009 66 Female 132 lb 12/18/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 8/23/2009 Male 12/22/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2009 80 Male 1/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2001 Female 162 lb 3/1/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/28/2010 Female 156 lb 3/3/2010 Physician United States
Primary
Secondary
Concomitant
Injection Site Reaction Hospitalization 1/27/2010 Female 153 lb 3/4/2010 Consumer France
Primary
Secondary
Concomitant

Drug Data