Diphenhydramine Hcl combined with Morphine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Overdose Death 42 Female 3/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 10/17/2003 37 Male 152 lb 3/14/2006 United States
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Thrombocytopenia Other Serious 42 Male 4/7/2006 United States
Primary
Concomitant
Polysubstance Abuse Other Serious 8/30/2003 38 Male 178 lb 5/12/2006 United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 5/30/2004 53 Female 7/17/2006 Other Health Professional United States
Primary
Secondary
Substance Abuse Death 11/4/2003 47 Female 150 lb 7/17/2006 Other Health Professional United States
Primary
Secondary
Accidental Overdose Death 12/27/2000 29 Male 7/17/2006 Other Health Professional United States
Primary
Secondary
Venoocclusive Liver Disease Life Threatening 9/13/2004 56 Female 190 lb 9/8/2006 United States
Primary
Concomitant
Substance Abuse Other Serious 5/5/2005 31 Male 258 lb 9/25/2006
Primary
Secondary
Swelling Required Intervention 8/13/2006 64 Male 242 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Cardio-respiratory Arrest Death 1/1/2004 60 Unknown 3/22/2007 Pharmacist United States
Primary
Secondary
Nausea Death 4/3/2007 41 Male 152 lb 5/2/2007 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Other Serious 3/13/2007 63 Female 196 lb 5/24/2007 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/5/2007 83 Female 185 lb 6/12/2007 Physician United States
Primary
Secondary
Concomitant
Urosepsis Hospitalization 9/11/2006 46 Male 147 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Inadequate Analgesia Hospitalization 7/29/2007 40 Male 123 lb 8/10/2007 Other Health Professional United States
Primary
Concomitant
Overdose Death 7/6/2004 37 196 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Substance Abuse Other Serious 6/8/2006 26 Male 150 lb 6/7/2007 Other Health Professional United States
Primary
Secondary
Peritonitis Hospitalization 6/30/2007 70 Female 153 lb 8/22/2007 Physician United States
Primary
Secondary
Concomitant
Death Death 1/1/2006 41 Male 2/13/2008 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2006 32 Female 2/13/2008 Physician United States
Primary
Secondary
Pulmonary Congestion Death 1/1/2006 46 Female 2/20/2008 Physician United States
Primary
Secondary
Nausea Hospitalization 2/15/2008 3/24/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 2/15/2008 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 8/28/2007 51 Female 207 lb 3/31/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pericardial Effusion Other Serious 8/28/2007 51 Female 207 lb 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Substance Abuse Other Serious 56 Female 6/20/2008 Canada
Primary
Secondary
Substance Abuse Other Serious 56 Female 6/24/2008 Canada
Primary
Secondary
Swelling Face Hospitalization 8/19/2008 62 Male 290 lb 10/20/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 5/31/2008 24 Female 207 lb 6/2/2008 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/1/2003 36 Female 4/6/2009 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2003 34 Male 280 lb 4/17/2009 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 4/19/2008 48 Female 121 lb 5/15/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 7/30/2009 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 4/14/2009 72 Male 7/31/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/16/2009 Male 8/10/2009 Physician United States
Primary
Secondary
Concomitant
Peripheral Coldness Other Serious 3/1/2008 60 Female 8/17/2009 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 70 Male 8/28/2009
Primary
Secondary
Concomitant
Venous Thrombosis Limb Other Serious 3/1/2008 60 Female 123 lb 9/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 9/3/2009 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 70 Male 9/10/2009 United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 6/1/2007 80 Male 196 lb 10/7/2009 Physician United States
Primary
Concomitant
Pseudomonas Infection Hospitalization 70 Male 10/7/2009 Physician United States
Primary
Secondary
Pyrexia Hospitalization 10/1/2009 Male 165 lb 12/3/2009 Pharmacist United States
Primary
Concomitant
Pyrexia Life Threatening 11/20/2009 Male 187 lb 12/24/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 3/31/2008 40 Female 123 lb 12/28/2009 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 10/5/2009 80 Male 1/6/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 Male 185 lb 1/8/2010 United States
Primary
Secondary
Concomitant
Product Quality Issue Required Intervention 4/18/2008 59 Female 125 lb 2/8/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 11/20/2003 61 Female 140 lb 4/8/2010 Lawyer United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 1/17/2005 40 Female 280 lb 4/12/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/17/2005 40 Female 280 lb 4/21/2010 Lawyer United States
Primary
Concomitant
Wound Infection Other Serious 1/1/2006 35 Male 5/21/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Wheezing Hospitalization 12/14/2004 39 Female 280 lb 6/21/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 11/20/2003 61 Female 140 lb 6/21/2010 Lawyer United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 7/5/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 7/5/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 40 Female 123 lb 8/31/2010 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 6/29/2010 53 Female 134 lb 8/25/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 8/30/2010 United States
Primary
Secondary
Concomitant
Visual Impairment Other Serious 7/12/1999 63 Female 9/1/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2006 35 Male 9/2/2010 United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 8/1/2007 77 Male 9/8/2010 Lawyer United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/14/2010 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 50 Female 9/16/2010 Lawyer United States
Primary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 9/17/2010 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2008 40 Female 132 lb 10/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 64 Male 187 lb 10/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Substance Abuse Death 44 Male 10/27/2010 Physician Canada
Primary
Secondary
Weight Decreased Other Serious 1/1/2001 43 Female 249 lb 11/10/2010 United States
Primary
Secondary
Concomitant
Wound Complication Other Serious 12/1/2005 39 Female 144 lb 11/18/2010 United States
Primary
Secondary
Concomitant
Infection Other Serious 8 Male 3/11/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Arrhythmia Hospitalization 9 Male 58 lb 3/28/2011 Consumer United States
Primary
Secondary
Concomitant
Dyspepsia Other Serious 12/1/2005 39 Female 144 lb 3/28/2011 United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2010 48 Female 128 lb 3/28/2011 Other Health Professional United States
Primary
Concomitant
Bone Pain Other Serious 1/4/2001 64 Female 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 1/1/2008 40 Female 132 lb 4/5/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Hospitalization 2/16/2009 72 Male 5/26/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Anxiety Other Serious 8/27/2002 81 Female 161 lb 5/26/2011 Consumer United States
Primary
Concomitant
Nephrogenic Anaemia Hospitalization 4/14/2009 72 Male 5/25/2011 Physician United States
Primary
Secondary
Concomitant
Depression Other Serious 8/27/2002 81 Female 161 lb 6/16/2011 Lawyer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 10/21/2010 13 Female 288 lb 6/13/2011 Physician United States
Primary
Secondary
Concomitant
Skin Haemorrhage Other Serious 1/4/2001 64 Female 6/22/2011 Consumer United States
Primary
Secondary
Concomitant
Renal Impairment Other Serious 12/31/2004 70 Male 165 lb 6/24/2011 Other Health Professional United States
Primary
Concomitant
Hypertriglyceridaemia Other Serious 1/5/2005 47 Female 249 lb 7/19/2011 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2006 42 Female 7/26/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 12/31/2004 70 Male 165 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Gastrooesophageal Reflux Disease Death Male 140 lb 8/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 11/20/2009 64 Male 185 lb 8/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Sudden Death Death 8/12/2011 61 Female 137 lb 8/25/2011 Physician United States
Primary
Concomitant
Exposed Bone In Jaw Hospitalization 1/1/2006 42 Female 8/26/2011 Physician United States
Primary
Concomitant
Abdominal Pain Upper Other Serious 12/1/2005 39 Female 144 lb 9/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2002 65 Female 9/20/2011 Lawyer United States
Primary
Secondary
Concomitant
Electrocardiogram T Wave Abnormal Other Serious Male 140 lb 11/1/2011 Lawyer United States
Primary
Secondary
Concomitant
Pain In Extremity Hospitalization 2/1/2003 51 Female 11/24/2011 Lawyer United States
Primary
Secondary
Concomitant
Impaired Gastric Emptying Hospitalization 11/27/2008 61 Female 174 lb 11/21/2011 Lawyer United States
Primary
Concomitant
Muscular Weakness Hospitalization 1/1/2010 48 Female 128 lb 11/28/2011 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Hospitalization 1/1/2010 48 Female 128 lb 12/2/2011 Physician United States
Primary
Concomitant
Brachial Plexopathy Other Serious 4/25/2005 42 Female 12/6/2011 Physician United States
Primary
Secondary
Concomitant
Rib Fracture Other Serious 4/25/2005 42 Female 12/12/2011 Lawyer United States
Primary
Secondary
Concomitant
Culture Wound Positive Hospitalization 9/24/2011 44 Female 99 lb 12/27/2011 Physician United States
Primary
Concomitant
Sudden Death Death 8/12/2011 61 Female 137 lb 12/28/2011 Other Health Professional United States
Primary
Concomitant
Drug Abuse Death 1/1/2010 27 Female 12/23/2011 Physician United States
Primary
Secondary
Death Death 1/1/2010 14 Male 12/26/2011 Physician United States
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 12/6/2011 63 Female 282 lb 1/2/2012 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2010 33 Male 12/28/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2010 36 Male 12/29/2011 Physician United States
Primary
Secondary
Delirium Hospitalization 78 Male 186 lb 1/5/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Cervical Dysplasia Other Serious 7/22/2010 49 Female 231 lb 1/6/2012 Physician United States
Primary
Secondary
Concomitant
Agitation Other Serious 78 Male 186 lb 1/26/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Death Death 54 Female 179 lb 1/27/2012 Consumer Canada
Primary
Secondary
Concomitant
Death Other Serious 54 Female 179 lb 1/31/2012 Other Health Professional Canada
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/19/2009 64 Male 185 lb 2/1/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Intentional Drug Misuse Death 27 Female 1/23/2012 Physician United States
Primary
Secondary
Neuropathy Peripheral Death 77 Male 2/2/2012 Consumer United States
Primary
Secondary
Concomitant
Substance Abuse Death 22 Male 180 lb 2/16/2012 Other Health Professional United States
Primary
Secondary
Drug Interaction Hospitalization 78 Male 2/29/2012 Other Health Professional United States
Primary
Secondary
Interacting
Hot Flush Other Serious 1/1/2006 42 Female 3/9/2012 Lawyer United States
Primary
Concomitant
Pain In Extremity Other Serious 2/1/2003 51 Female 3/20/2012 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 3/21/2012 Consumer United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2012 73 Female 3/22/2012 Consumer United States
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization 1/20/2008 58 Male 140 lb 4/5/2012 Lawyer United States
Primary
Secondary
Concomitant
Sinus Congestion Other Serious 1/1/2006 35 Male 4/9/2012 Lawyer United States
Primary
Concomitant
Pancytopenia Hospitalization 11/23/2007 47 Female 194 lb 4/13/2012 Physician United States
Primary
Secondary
Concomitant
Malnutrition Other Serious 1/1/2012 73 Female 4/19/2012 Consumer United States
Primary
Secondary
Concomitant
Intervertebral Disc Protrusion Other Serious 1/1/2008 37 Male 4/17/2012 Other Health Professional United States
Primary
Concomitant
Drug Abuse Other Serious 21 Male 4/24/2012 Physician United States
Primary
Secondary
Osteomyelitis Other Serious 2/24/2012 11 Female 116 lb 5/2/2012 Physician United States
Primary
Concomitant
Toxicity To Various Agents Death 21 Male 5/2/2012 Consumer United States
Primary
Secondary
Neoplasm Malignant Other Serious 1/1/2012 73 Female 5/9/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Hypertension Death 2/24/2012 11 Female 116 lb 5/22/2012 Other Health Professional United States
Primary
Concomitant
Food Poisoning Other Serious 2/1/2003 51 Female 5/28/2012 Pharmacist United States
Primary
Secondary
Concomitant
Postoperative Wound Infection Other Serious 1/1/2008 37 Male 5/16/2012 Lawyer United States
Primary
Concomitant
Thyroid Mass Hospitalization 1/1/2006 35 Male 5/22/2012 Lawyer United States
Primary
Concomitant
Salpingo-oophorectomy Other Serious 9/21/2011 44 Female 99 lb 6/12/2012 Physician United States
Primary
Concomitant
Multiple Allergies Other Serious Male 170 lb 6/19/2012 Lawyer United States
Primary
Concomitant
Osteopenia Other Serious 2/1/2003 51 Female 7/5/2012 Physician United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 6/20/2012 76 Male 183 lb 7/10/2012 Other Health Professional United States
Primary
Concomitant
Cholestasis Hospitalization 5/22/2012 49 234 lb 7/19/2012 Physician United States
Primary
Secondary
Concomitant
Interacting
Pleural Effusion Other Serious 3/29/2012 70 Female 194 lb 8/1/2012 Physician United States
Primary
Secondary
Concomitant
Lactose Intolerance Hospitalization 9/17/2002 43 Female 205 lb 8/3/2012 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 11/3/2005 63 Male 161 lb 8/7/2012 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Death 2/1/2003 51 Female 8/10/2012 Pharmacist United States
Primary
Secondary
Concomitant
Haemorrhage Intracranial Death 3/27/2012 51 Female 126 lb 8/17/2012 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 2011 36 Female 1/17/2013 Us
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/28/2013 77 Male 4/24/2013 Physician Us
Primary
Secondary
Concomitant
Pituitary Tumour Benign Disability 6/8/2012 35 Female 10/29/2012 Other Health Professional Gb
Primary
Secondary
Concomitant
Sepsis Life Threatening 3/27/2012 51 Female 126 lb 2/7/2013 Physician Us
Primary
Secondary
Concomitant

Drug Data