Diphenhydramine Hcl combined with Methylprednisolone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Tachycardia Hospitalization 76 Male 5/19/2006 Physician United States
Primary
Concomitant
Oedema Hospitalization Female 6/12/2006 Physician Greece
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 5/3/1997 62 Male 7/5/2006 Other Health Professional United States
Primary
Concomitant
Angioneurotic Oedema Required Intervention 6/6/2006 64 Male 121 lb 6/28/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 7/23/2006 58 Male 313 lb 7/28/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 43 Female 9/11/2006 Pharmacist United States
Primary
Concomitant
Suicide Attempt Life Threatening 12/6/2005 42 Female 12/5/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Hospitalization 11/17/2006 44 Male 179 lb 11/30/2006 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Required Intervention 4/21/2006 66 235 lb 2/13/2007 Physician United States
Primary
Concomitant
Screaming Hospitalization 4/12/2007 61 Male 7/9/2007 Pharmacist United States
Primary
Secondary
Overdose Death 7/8/2007 24 Male 207 lb 7/19/2007 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Other Serious 10/1/1998 Male 196 lb 7/25/2007
Primary
Concomitant
Tremor Hospitalization 7/1/2007 66 Female 144 lb 7/30/2007 Physician United States
Primary
Secondary
Concomitant
Renal Artery Thrombosis Hospitalization 12/18/2003 44 Male 157 lb 2/28/2005 Other Health Professional United States
Primary
Concomitant
Appendicitis Hospitalization 8/12/2006 37 Male 285 lb 10/8/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Staphylococcal Bacteraemia Life Threatening 10/7/2007 14 Male 203 lb 11/8/2007 Physician United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 9/28/2007 21 Female 150 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Pseudomonas Infection Required Intervention 9/27/2007 39 Male 154 lb 11/1/2007 Pharmacist United States
Primary
Concomitant
Meningitis Enterococcal Hospitalization 11/10/2007 1 Female 11/30/2007 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 9/28/2007 21 Female 150 lb 12/3/2007 Physician United States
Primary
Secondary
Concomitant
Pruritus Other Serious 11/19/2007 42 Female 248 lb 11/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Septic Shock Death 12/31/2007 65 Male 239 lb 1/16/2008 Physician United States
Primary
Secondary
Concomitant
Sepsis Death 12/31/2007 65 Male 239 lb 1/31/2008 Physician United States
Primary
Secondary
Concomitant
Urticaria Required Intervention 2/1/2008 62 Male 262 lb 2/29/2008 Pharmacist United States
Primary
Concomitant
Pneumonia Other Serious 4/5/2008 53 Female 157 lb 6/12/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Proctitis Other Serious Female 7/2/2008 Physician Greece
Primary
Secondary
Concomitant
Proctitis Other Serious Female 7/2/2008 Physician Greece
Primary
Secondary
Concomitant
Staphylococcal Infection Death 3/1/2007 59 Male 193 lb 7/10/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Aspiration Other Serious 13 Female 9/24/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1/1/2004 60 Female 10/2/2008 Other Health Professional United States
Primary
Concomitant
Multi-organ Failure Hospitalization 44 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Fungal Other Serious 1/1/2005 68 Male 10/2/2008 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 51 Male 10/3/2008 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 10/1/2006 60 Female 10/3/2008 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 13 Female 10/9/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 11 Male 10/10/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Pyrexia Hospitalization 13 Female 10/13/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Transplant Rejection Hospitalization 11 Male 10/13/2008 Other Health Professional Philippines
Primary
Secondary
Concomitant
Pyrexia Hospitalization 13 Female 11/7/2008 Physician Philippines
Primary
Secondary
Concomitant
Transaminases Increased Other Serious 42 Female 1/13/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Adverse Event Other Serious 39 Female 1/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Rheumatoid Arthritis Hospitalization 27 Female 5/21/2009 Consumer United Kingdom
Primary
Concomitant
Swollen Tongue Other Serious 5/16/2009 Female 5/29/2009 Physician
Primary
Secondary
Concomitant
Swollen Tongue Other Serious 5/16/2009 Female 6/10/2009 Physician
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 30 Female 244 lb 6/11/2009 United States
Primary
Concomitant
Rheumatoid Arthritis Hospitalization 27 Female 6/5/2009 Consumer United Kingdom
Primary
Concomitant
Scleritis Other Serious 57 Male 6/19/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Disability 11/2/2008 68 Female 163 lb 6/17/2009 Pharmacist United States
Primary
Concomitant
Total Lung Capacity Decreased Hospitalization 48 Male 6/29/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 42 Male 213 lb 7/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2003 42 Female 285 lb 7/21/2009 United States
Primary
Concomitant
Interstitial Lung Disease Hospitalization 6/29/2009 Male 189 lb 8/18/2009 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 66 Female 9/3/2009 Lawyer United States
Primary
Concomitant
Oculogyric Crisis Other Serious 4 Male 9/8/2009 Physician United Kingdom
Primary
Secondary
Oculogyric Crisis Other Serious 4 Male 9/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Oculogyric Crisis Other Serious 4 Male 9/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 Female 10/8/2009 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 11/20/2009 Physician United States
Primary
Secondary
Concomitant
Penile Ulceration Required Intervention 7/29/2009 Male 15 lb 11/13/2009 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 16 Male 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 12/7/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 16 Male 12/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Death 12/11/2009 Other Health Professional United Kingdom
Primary
Secondary
Disease Progression Hospitalization 47 Female 12/17/2009
Primary
Secondary
Concomitant
Pneumonia Other Serious 3/1/2009 77 Female 1/8/2010 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 9/16/2009 22 Male 169 lb 1/7/2010 Physician United States
Primary
Secondary
Concomitant
Product Quality Issue Required Intervention 4/18/2008 59 Female 125 lb 2/8/2010 United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 1/17/2005 40 Female 280 lb 4/12/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/17/2005 40 Female 280 lb 4/21/2010 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/17/2005 40 Female 280 lb 4/27/2010 Lawyer United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Withdrawal Syndrome Hospitalization 12/14/2004 39 Female 280 lb 5/26/2010 Consumer United States
Concomitant
Wheezing Hospitalization 12/14/2004 39 Female 280 lb 6/21/2010 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/13/2002 42 Male 213 lb 7/6/2010 United States
Primary
Concomitant
Sepsis Other Serious 1/1/2008 42 Female 9/2/2010 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 6/14/2010 61 Male 185 lb 9/7/2010 Physician United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 9/16/2009 22 Male 169 lb 9/28/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 16 Male 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Tachycardia Hospitalization 4/28/2010 19 Female 115 lb 11/8/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious Female 154 lb 11/17/2010 Consumer United Kingdom
Primary
Concomitant
Oropharyngeal Pain Other Serious 7/31/2009 71 Female 155 lb 4/7/2011 Consumer Canada
Primary
Concomitant
Crohn's Disease Hospitalization 11/3/2010 26 Male 4/8/2011 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 6/22/2010 62 Male 4/13/2011 Consumer United Kingdom
Primary
Concomitant
Nasopharyngitis Other Serious 7/31/2009 71 Female 155 lb 5/31/2011 Consumer Canada
Primary
Concomitant
Asthenia Hospitalization Female 172 lb 6/6/2011 Consumer United Kingdom
Primary
Concomitant
Blood Pressure Increased 2/16/2011 50 Female 6/14/2011 Other Health Professional United States
Primary
Concomitant
Nausea Hospitalization Female 172 lb 6/24/2011 Consumer United Kingdom
Primary
Concomitant
Acute Myocardial Infarction Death 6/30/2011 Physician China
Primary
Concomitant
Graft Loss Other Serious 6/30/2011 Physician China
Primary
Concomitant
Glomerulonephropathy Other Serious 6/30/2011 Physician China
Primary
Concomitant
Graft Loss Other Serious 6/30/2011 Physician China
Primary
Concomitant
Immunodeficiency Other Serious 7/31/2009 71 Female 155 lb 7/5/2011 Consumer Canada
Primary
Concomitant
Asthenia Hospitalization Female 172 lb 7/6/2011 Consumer Canada
Primary
Concomitant
Graft Loss Other Serious 7/6/2011 Physician China
Primary
Concomitant
Acute Myocardial Infarction Death 7/6/2011 Physician China
Primary
Concomitant
Graft Loss Other Serious 7/6/2011 Physician China
Primary
Concomitant
Glomerulonephropathy Other Serious 7/6/2011 Physician China
Primary
Concomitant
Diabetes Insipidus Hospitalization 3/21/2011 49 Male 6/28/2011 Other Health Professional United States
Primary
Concomitant
Anaphylactic Reaction Other Serious 4/13/2011 13 Female 96 lb 7/14/2011 Physician United States
Primary
Concomitant
Conjunctivitis Other Serious 1/1/2000 44 Female 268 lb 7/29/2011 Consumer United States
Primary
Concomitant
Aspergillosis Death 14 Female 7/24/2011 Other Health Professional France
Primary
Concomitant
Toxicity To Various Agents Other Serious 16 Female 7/25/2011 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Other Serious 11/13/2002 42 Male 245 lb 8/2/2011 Lawyer United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/5/2011 Physician United States
Primary
Concomitant
Sepsis Other Serious 58 Female 8/8/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 8/8/2011 Physician United States
Primary
Concomitant
Acute Respiratory Failure Other Serious 58 Female 8/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Other Serious 7/25/2011 67 Male 182 lb 8/28/2011 Physician United States
Primary
Concomitant
Colitis Other Serious 7/25/2011 67 Male 182 lb 8/30/2011 Physician United States
Primary
Concomitant
Failure To Thrive Other Serious 7/25/2011 67 Male 182 lb 9/2/2011 Physician United States
Primary
Concomitant
Urticaria Hospitalization 9/1/2011 45 Female 9/21/2011 Consumer United Kingdom
Primary
Concomitant
Central Venous Catheterisation Other Serious 6/21/2011 38 Female 234 lb 10/6/2011 Pharmacist United States
Primary
Concomitant
Choking Disability 3/1/2010 74 Male 122 lb 10/5/2011 Lawyer United States
Primary
Concomitant
Haemolysis Hospitalization 5/6/2011 24 Male 195 lb 8/18/2011 Physician United States
Primary
Concomitant
Death Death Female 10/27/2011 Canada
Primary
Concomitant
Pruritus Life Threatening 10/10/2011 32 Female 10/28/2011 Other Health Professional Panama
Primary
Concomitant
Skin Papilloma Hospitalization 10/1/2008 64 Female 119 lb 10/31/2011 Brazil
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 11/8/2011 Colombia
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death Female 11/8/2011 Other Health Professional Colombia
Primary
Concomitant
Death Other Serious 11/23/2010 37 Male 232 lb 11/23/2011 Canada
Primary
Concomitant
Enteritis Infectious Hospitalization 8/7/2011 62 Female 180 lb 11/28/2011 Canada
Primary
Concomitant
Infection Disability 4/28/2010 19 Female 115 lb 11/29/2011 Physician Japan
Primary
Concomitant
Arthralgia Hospitalization 6/8/2010 61 Male 185 lb 12/5/2011 Pharmacist United States
Primary
Concomitant
Nasopharyngitis Other Serious 2/5/2011 54 Female 12/9/2011 Canada
Primary
Concomitant
Wound Other Serious 11/1/2011 64 Male 209 lb 12/14/2011 Other Health Professional Canada
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious Female 12/23/2011 Colombia
Primary
Secondary
Concomitant
Pulmonary Alveolar Haemorrhage Death 24 Female 12/23/2011 Other Health Professional Colombia
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 12/1/2011 76 Male 185 lb 12/23/2011 Consumer Canada
Primary
Concomitant
Hypoaesthesia Other Serious 11/1/2011 54 Male 165 lb 12/27/2011 Canada
Primary
Concomitant
Basal Cell Carcinoma Other Serious 12/1/2010 69 Female 198 lb 1/3/2012 Consumer Canada
Primary
Concomitant
Tachycardia Hospitalization Female 140 lb 1/3/2012 Canada
Primary
Concomitant
Hepatitis B Other Serious Female 150 lb 1/5/2012 Canada
Primary
Concomitant
Nasopharyngitis Hospitalization 1/6/2012 73 Female 168 lb 1/18/2012 Canada
Primary
Concomitant
Diabetes Mellitus Death 11/1/2011 64 Male 209 lb 1/24/2012 Other Health Professional Canada
Primary
Concomitant
Urinary Tract Infection Other Serious Female 146 lb 1/24/2012 Brazil
Primary
Concomitant
Cough Life Threatening 10/10/2011 32 Female 1/27/2012 Other Health Professional Panama
Primary
Concomitant
Skin Cancer Other Serious 4/1/2011 52 Male 152 lb 1/27/2012 Consumer Canada
Primary
Concomitant
Hepatitis B Other Serious 61 Male 1/30/2012 Physician United States
Primary
Concomitant
Condition Aggravated Hospitalization 59 Male 1/30/2012 United States
Primary
Concomitant
Pain Other Serious Female 146 lb 2/1/2012 Physician Brazil
Primary
Concomitant
Pulmonary Oedema Other Serious 8/23/2011 58 Male 148 lb 2/10/2012 Physician Japan
Primary
Concomitant
Hypoaesthesia Life Threatening 10/1/2008 64 Female 119 lb 2/16/2012 Physician Brazil
Primary
Concomitant
Disease Progression Other Serious 11/1/2011 64 Male 209 lb 2/21/2012 Other Health Professional Canada
Primary
Concomitant
Vomiting Other Serious 2/7/2012 55 Female 190 lb 2/28/2012 Canada
Primary
Concomitant
Drug Ineffective For Unapproved Indication Life Threatening 10 Female 3/2/2012 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 12/18/2011 55 Male 176 lb 3/2/2012 Consumer Canada
Primary
Concomitant
Depression Other Serious 3/5/2012 54 Female 125 lb 3/5/2012 Consumer Canada
Primary
Concomitant

Drug Data