Diovan combined with Nexavar

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Convulsion Hospitalization 3/26/2006 73 Female 4/4/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 2/17/2006 68 Male 4/21/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 2/17/2006 68 Male 4/28/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 2/17/2006 68 Male 5/19/2006 United States
Primary
Concomitant
Pain In Extremity 1/30/2006 71 Female 4/24/2006 United States
Primary
Concomitant
Tongue Disorder Other Serious 3/11/2006 58 Female 148 lb 4/24/2006 United States
Primary
Concomitant
Weight Decreased 12/1/2005 79 Female 109 lb 7/12/2006 United States
Primary
Concomitant
Urine Odour Abnormal 3/9/2006 81 Female 145 lb 7/12/2006 United States
Primary
Concomitant
Rash Pruritic 2/1/2006 85 Female 7/12/2006 United States
Primary
Concomitant
Tongue Disorder Other Serious 3/11/2006 58 Female 148 lb 7/12/2006 United States
Primary
Concomitant
Weight Decreased 3/3/2006 70 Female 7/12/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 8/1/2006 79 Male 192 lb 10/3/2006 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 3/26/2006 74 Female 10/10/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 8/1/2006 79 Male 192 lb 10/12/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 1/1/2006 79 Male 192 lb 10/31/2006 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 9/17/2006 67 Male 132 lb 11/7/2006 Other Health Professional Germany
Primary
Concomitant
Vascular Encephalopathy Other Serious 9/17/2006 67 Male 132 lb 12/13/2006 Other Health Professional Germany
Primary
Concomitant
Vascular Encephalopathy Other Serious 9/17/2006 67 Male 132 lb 12/20/2006 Other Health Professional Germany
Primary
Concomitant
Vision Blurred Other Serious 2/17/2006 69 Male 1/8/2007 Physician United States
Primary
Concomitant
Vulvovaginal Mycotic Infection Other Serious 3/11/2006 58 Female 150 lb 10/23/2006 United States
Primary
Concomitant
Urine Odour Abnormal 3/9/2006 81 Female 145 lb 10/23/2006 United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2005 69 Male 168 lb 1/23/2007 United States
Primary
Secondary
Concomitant
Weight Decreased 3/3/2006 70 Female 1/23/2007 Other Health Professional United States
Primary
Concomitant
Skin Papilloma Hospitalization 1/1/2007 67 Female 154 lb 5/16/2007 United States
Primary
Concomitant
Testicular Pain 3/25/2007 56 Male 8/1/2007 United States
Primary
Concomitant
Testicular Abscess Other Serious 10/1/2006 73 Male 11/6/2007 Other Health Professional United States
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/7/2007 52 Female 106 lb 1/14/2008 Physician China
Primary
Concomitant
Sinusitis Other Serious 12/10/2007 Male 3/7/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Face Hospitalization 2/1/2008 78 Male 9/15/2008 United States
Primary
Concomitant
Swelling Face Other Serious 2/1/2008 78 Male 10/3/2008 United States
Primary
Concomitant
Stomatitis Hospitalization 7/2/2008 64 Male 10/31/2008 Physician Japan
Primary
Concomitant
Hypertension Other Serious 8/1/2008 62 Male 11/25/2008 Pharmacist Spain
Primary
Concomitant
Inferior Vena Caval Occlusion Life Threatening 8/21/2008 78 Female 121 lb 12/12/2008 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Hospitalization 11/25/2008 57 Female 110 lb 12/18/2008 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/2/2008 64 Male 12/29/2008 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/13/2008 64 Male 137 lb 1/9/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/2/2008 64 Male 1/16/2009 Physician Japan
Primary
Concomitant
Renal Cell Carcinoma Stage Iv Life Threatening 8/21/2008 78 Female 121 lb 1/22/2009 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 8/30/2008 60 Male 152 lb 2/25/2009 Physician Japan
Primary
Concomitant
Swelling Face Other Serious 2/1/2008 78 Male 2/25/2009 United States
Primary
Concomitant
Sunburn Other Serious 12/31/2007 53 Male 161 lb 3/12/2009 Physician United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 8/30/2008 60 Male 152 lb 3/19/2009 Physician Japan
Primary
Concomitant
Rash Life Threatening 7/22/2008 73 Female 134 lb 3/24/2009 Japan
Primary
Concomitant
Performance Status Decreased Other Serious 1/31/2009 91 Male 154 lb 3/31/2009 United States
Primary
Concomitant
Toxic Skin Eruption Other Serious 8/30/2008 60 Male 152 lb 4/3/2009 Physician Japan
Primary
Concomitant
Hypertension Other Serious 3/23/2009 72 Male 4/20/2009 Other Health Professional Spain
Primary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 5/13/2009 Physician Japan
Primary
Concomitant
Embolic Stroke Hospitalization 4/23/2009 72 Female 148 lb 5/14/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Embolic Stroke Hospitalization 4/23/2009 72 Female 148 lb 5/15/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Cell Carcinoma Life Threatening 7/22/2008 73 Female 134 lb 5/15/2009 Physician Japan
Primary
Concomitant
Embolic Stroke Hospitalization 4/23/2009 72 Female 148 lb 5/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 6/1/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 6/5/2009 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 6/12/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/19/2008 59 Male 183 lb 6/12/2009 Physician Japan
Primary
Concomitant
Platelet Count Decreased Other Serious 12/19/2008 59 Male 183 lb 6/22/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 6/19/2009 65 Male 154 lb 7/30/2009 Physician Japan
Primary
Concomitant
Rash Hospitalization 6/18/2009 81 Male 123 lb 8/3/2009 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 8/7/2009 Physician Japan
Primary
Secondary
Concomitant
Sinus Bradycardia Life Threatening 6/23/2009 69 Male 157 lb 8/14/2009 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 8/31/2009 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Hospitalization 7/17/2009 83 Female 9/8/2009 Physician Japan
Primary
Concomitant
Stomatitis Hospitalization 7/17/2009 83 Female 9/16/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2009 68 Female 106 lb 9/24/2009 Physician Japan
Primary
Concomitant
Hypophosphataemia Death 8/25/2008 Female 10/2/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/19/2009 65 Male 154 lb 10/20/2009 Physician Japan
Primary
Concomitant
Renal Disorder Hospitalization 9/7/2009 59 Male 143 lb 11/4/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2009 81 Male 146 lb 11/6/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 11/9/2009 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/22/2009 72 Male 152 lb 11/20/2009 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 11/23/2009 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/23/2009 79 Male 12/1/2009 Physician Japan
Primary
Concomitant
Hypertension Death 9/20/2009 57 Male 176 lb 12/3/2009 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 12/10/2009 Physician Japan
Primary
Concomitant
Pancytopenia Hospitalization 11/13/2008 65 Female 12/17/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/1/2009 67 Female 123 lb 12/18/2009 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 6/24/2009 68 Female 106 lb 12/18/2009 Physician Japan
Primary
Secondary
Concomitant
Somnolence Other Serious 11/8/2009 72 Male 121 lb 12/23/2009 Physician Japan
Primary
Concomitant
Hepatic Neoplasm Malignant Other Serious 7/21/2009 79 Male 1/8/2010 Physician Japan
Primary
Concomitant
Transaminases Increased Hospitalization 10/23/2009 84 Male 115 lb 1/14/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 1/25/2010 Physician Japan
Primary
Concomitant
Skin Hypertrophy Other Serious 7/30/2009 54 Male 198 lb 1/25/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/23/2009 80 Male 137 lb 1/25/2010 United States
Primary
Concomitant
Thyroiditis Hospitalization 12/11/2009 74 Male 130 lb 2/1/2010 Physician Japan
Primary
Concomitant
Renal Impairment Hospitalization 11/19/2009 79 Male 172 lb 2/2/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Hospitalization 12/10/2009 74 Male 2/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/31/2009 59 Male 172 lb 2/11/2010 Physician Japan
Primary
Concomitant
Pulmonary Oedema Life Threatening 6/15/2009 51 Male 183 lb 2/11/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/24/2009 82 Male 146 lb 2/15/2010 Physician Japan
Primary
Concomitant
Stomatitis Other Serious 7/22/2008 73 Female 134 lb 2/22/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Cell Carcinoma Life Threatening 8/21/2008 78 Female 121 lb 2/23/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/20/2010 61 Female 137 lb 3/2/2010 Physician Japan
Primary
Concomitant
Liver Disorder Hospitalization 10/23/2009 84 Male 115 lb 3/9/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Death 11/18/2009 81 Female 112 lb 3/10/2010 Physician Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/11/2010 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 3/15/2010 Other Health Professional Japan
Primary
Concomitant
Protein Urine Other Serious 4/25/2008 68 Male 110 lb 3/18/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Other Serious 7/28/2009 79 Male 3/24/2010 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 3/24/2010 Physician Japan
Primary
Concomitant
Liver Carcinoma Ruptured Death 11/18/2009 81 Female 112 lb 3/31/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 2/26/2010 66 Female 110 lb 3/31/2010 Physician Japan
Primary
Concomitant
Skin Exfoliation Other Serious 2/11/2009 71 Male 143 lb 4/12/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/16/2009 78 Female 112 lb 4/12/2010 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 10/12/2009 63 Female 148 lb 4/13/2010 Physician Japan
Primary
Secondary
Concomitant
Herpes Zoster Hospitalization 1/20/2010 61 Female 137 lb 4/16/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 1/15/2010 79 Male 154 lb 4/20/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 4/23/2010 Other Health Professional Japan
Primary
Concomitant
Skin Ulcer Other Serious 10/1/2009 83 Male 157 lb 5/7/2010 United States
Primary
Concomitant
Renal Cell Carcinoma Life Threatening 8/21/2008 78 Female 121 lb 5/11/2010 Physician Japan
Primary
Concomitant
Pruritus Other Serious 7/26/2009 48 Male 123 lb 5/11/2010 Physician Japan
Primary
Concomitant
Vomiting Other Serious 4/22/2009 72 Male 152 lb 5/14/2010 Physician Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/20/2010 61 Female 137 lb 5/19/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/31/2009 59 Male 172 lb 5/24/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 11/5/2009 77 Male 117 lb 5/27/2010 Other Health Professional Japan
Primary
Concomitant
Herpes Zoster Hospitalization 1/20/2010 61 Female 137 lb 6/1/2010 Physician Japan
Primary
Concomitant
Skin Hypertrophy Other Serious 7/30/2009 54 Male 198 lb 6/3/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 8/31/2009 67 Female 123 lb 6/9/2010 Physician Japan
Primary
Concomitant
Platelet Count Decreased Death 12/19/2008 59 Male 183 lb 6/17/2010 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 5/10/2010 68 Male 150 lb 6/23/2010 Physician Japan
Primary
Secondary
Concomitant
Drug Eruption Hospitalization 5/25/2010 79 Female 110 lb 7/12/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 7/11/2009 46 Female 112 lb 8/4/2010 Physician Japan
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/11/2009 46 Female 112 lb 8/5/2010 Physician Japan
Primary
Concomitant
Pyrexia Hospitalization 7/25/2010 64 Male 8/5/2010 Pharmacist Japan
Primary
Concomitant
Drug Eruption Hospitalization 5/25/2010 79 Female 110 lb 8/11/2010 Physician Japan
Primary
Concomitant
Sinus Bradycardia Life Threatening 6/9/2009 69 Male 157 lb 8/18/2010 Physician Japan
Primary
Concomitant
Toxic Skin Eruption Other Serious 8/30/2008 60 Male 152 lb 8/27/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 10/18/2009 85 Male 108 lb 9/3/2010 Physician Japan
Primary
Concomitant
Hypertension Hospitalization 12/4/2009 64 Male 165 lb 9/9/2010 Pharmacist United States
Primary
Concomitant
Death Death 3/7/2010 58 Female 154 lb 9/23/2010 Physician Japan
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Hospitalization 5/10/2010 68 Male 150 lb 9/29/2010 Physician Japan
Primary
Secondary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Hospitalization 7/13/2010 60 Male 11/4/2010 Physician Japan
Primary
Concomitant
Multi-organ Failure Other Serious 9/29/2010 77 Female 110 lb 11/8/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 10/18/2009 85 Male 108 lb 11/9/2010 Physician Japan
Primary
Concomitant
Heart Rate Irregular Hospitalization 5/7/2007 52 Female 106 lb 11/12/2010 China
Primary
Concomitant
Rash Hospitalization 6/18/2009 81 Male 123 lb 11/16/2010 Physician Japan
Primary
Concomitant
Heart Rate Irregular Other Serious 5/7/2007 52 Female 106 lb 11/18/2010 China
Primary
Concomitant
Palmar-plantar Erythrodysaesthesia Syndrome Other Serious 8/25/2009 59 Male 172 lb 11/19/2010 Physician Japan
Primary
Concomitant
Oedema Peripheral Hospitalization 10/18/2009 85 Male 106 lb 12/28/2010 Physician Japan
Primary
Concomitant
Hypertension Other Serious 1/15/2010 78 Male 153 lb 1/14/2011 Physician Japan
Primary
Concomitant
Erythema Hospitalization 8/12/2010 76 Male 128 lb 1/20/2011 Physician Japan
Primary
Concomitant
Hepatic Function Abnormal Other Serious 12/13/2010 69 Male 130 lb 1/31/2011 Physician Japan
Primary
Concomitant
Electrolyte Imbalance Hospitalization 8/1/2008 70 Female 2/4/2011 Pharmacist United States
Primary
Concomitant
Pleural Effusion Other Serious 12/13/2010 53 Male 115 lb 2/1/2011 Physician Japan
Primary
Concomitant
Haematuria Life Threatening 12/13/2010 53 Male 115 lb 2/8/2011 Physician Japan
Primary
Concomitant
Rash Other Serious 12/14/2010 64 Male 110 lb 2/9/2011 Physician Japan
Primary
Secondary
Concomitant
Hepatic Encephalopathy Death 8/31/2009 58 Male 172 lb 2/23/2011 Physician Japan
Primary
Concomitant
Neurogenic Shock Death 9/29/2010 83 Male 148 lb 3/2/2011 Physician Japan
Primary
Concomitant
Alanine Aminotransferase Increased Hospitalization 7/13/2010 59 Male 3/21/2011 Physician Japan
Primary
Concomitant
Necrotising Fasciitis Death 8/6/2010 59 Male 3/23/2011 Physician United States
Primary
Concomitant
Rash Hospitalization 12/14/2010 64 Male 110 lb 3/23/2011 Physician Japan
Primary
Secondary
Concomitant

Drug Data