Diltiazem combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/19/2004 21 9/12/2005 Physician United States
Primary
Concomitant
Transfusion Reaction Other Serious 2/1/2004 57 Male 2/8/2006 Canada
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 12/1/2005 43 Male 168 lb 2/28/2006 Poland
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Asthenia Required Intervention 3/10/2006 75 Female 3/12/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Required Intervention 7/20/2005 74 Female 5/16/2006 Pharmacist United States
Primary
Secondary
Wound Infection Hospitalization 62 Male 223 lb 4/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 3/30/2006 65 Female 5/12/2006 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 69 Female 176 lb 6/8/2006 Canada
Primary
Concomitant
Renal Failure Acute Hospitalization 10/21/2006 78 Male 11/3/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Stomatitis Hospitalization 2/18/2006 59 Male 139 lb 2/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Completed Suicide Death 38 10/26/2007 Physician United States
Primary
Secondary
Completed Suicide Death 38 10/31/2007 Physician United States
Primary
Secondary
Urinary Tract Infection Hospitalization 11/29/2004 25 Male 12/5/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 10/1/2007 Female 12/7/2007 Consumer United States
Primary
Concomitant
Bradycardia Hospitalization 11/19/2007 53 Male 12/12/2007 Pharmacist United States
Primary
Secondary
Vascular Injury Other Serious 5/21/2007 65 Female 101 lb 11/30/2007 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 4/14/2008 70 Male 5/29/2008 United States
Primary
Concomitant
Injection Site Pain 3/12/2008 Female 145 lb 6/13/2008 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Required Intervention 75 Female 6/10/2008 Canada
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2007 Female 182 lb 6/17/2008 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 6/28/2003 Male 320 lb 6/19/2008 Lawyer United States
Primary
Concomitant
Kidney Transplant Rejection Other Serious 10/7/2008 Male 260 lb 12/3/2008 Physician Canada
Primary
Secondary
Concomitant
Peripheral Coldness Other Serious 8/14/2008 Female 121 lb 12/10/2008 Pharmacist Canada
Primary
Concomitant
Thrombocytopenia Hospitalization 11/28/2008 Female 119 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Product Quality Issue Hospitalization 5/1/2008 57 Female 185 lb 1/9/2009 Consumer United States
Primary
Concomitant
Tooth Extraction Other Serious 1/1/2006 Female 1/16/2009 Physician United States
Primary
Concomitant
Multiple Drug Overdose Intentional Death 1/29/2009 Other Health Professional United States
Primary
Secondary
Renal Failure Acute Hospitalization 8/21/2008 63 Female 152 lb 2/25/2009 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/9/2009 Consumer United Kingdom
Primary
Secondary
Demyelination Other Serious 7/1/2008 Female 189 lb 3/12/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/16/2009 43 Female 233 lb 3/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 3/23/2009 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 56 Male 4/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Oxygen Saturation Decreased Required Intervention 2/6/2009 77 Male 196 lb 3/18/2009 Pharmacist United States
Primary
Concomitant
Wheezing 5/4/2009 Male 5/8/2009 Pharmacist
Primary
Concomitant
Pulse Absent Other Serious 1/1/2009 Male 5/20/2009 Physician United States
Primary
Secondary
Concomitant
Ocular Hyperaemia Other Serious 10/3/2008 Male 192 lb 6/2/2009 Consumer United States
Primary
Concomitant
Ocular Hyperaemia Other Serious 10/3/2008 Male 192 lb 6/22/2009 Other Health Professional United States
Primary
Concomitant
Wound Secretion Other Serious 7/1/2006 61 Male 7/7/2009 Lawyer United States
Primary
Secondary
Concomitant
Application Site Urticaria 7/2/2009 Female 7/7/2009 Pharmacist
Primary
Concomitant
International Normalised Ratio Increased Other Serious 73 Male 7/9/2009 United States
Primary
Concomitant
Interacting
Ocular Hyperaemia Other Serious 10/3/2008 Male 192 lb 7/24/2009 Other Health Professional United States
Primary
Concomitant
Bradycardia Hospitalization 6/5/2009 83 Male 242 lb 7/30/2009 Pharmacist United States
Primary
Secondary
Ureteric Cancer Death 71 Male 7/22/2009 United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 167 lb 7/22/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/18/2009 56 Male 207 lb 8/12/2009 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 1/2/2007 64 Male 272 lb 8/12/2009 Pharmacist United States
Primary
Concomitant
Speech Disorder 6/8/2009 67 Male 8/6/2009 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 8/5/2009 United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/14/2009 Physician Germany
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 1/1/2009 Male 8/14/2009 Physician United States
Primary
Secondary
Concomitant
Enuresis 7/13/2009 59 Male 249 lb 8/14/2009 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/17/2009 Physician Germany
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/10/2009 United States
Primary
Concomitant
Ureteric Cancer Death 71 Male 8/4/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 8/11/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 4/21/2008 66 Male 179 lb 8/13/2009 Physician United States
Primary
Concomitant
Drug Interaction Other Serious 69 Female 8/14/2009 France
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 7/19/2009 Male 208 lb 8/20/2009 United States
Primary
Secondary
Concomitant
Thrombosis Other Serious 54 Male 200 lb 8/20/2009 Consumer United States
Primary
Concomitant
Transplant Rejection Hospitalization 10/30/2008 56 Male 309 lb 8/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pruritus 10/2/2008 Female 165 lb 8/22/2009 Other Health Professional
Primary
Concomitant
Pruritus 8/1/2008 Male 8/22/2009 Other Health Professional United States
Primary
Concomitant
Pruritus 12/1/2008 Male 8/22/2009 United States
Primary
Concomitant
Flushing 3/1/2009 Male 8/22/2009 United States
Primary
Concomitant
Heart Rate Irregular 7/7/2009 Female 8/23/2009 United States
Primary
Concomitant
Swollen Tongue Hospitalization 8/1/2009 Female 8/26/2009 Consumer United States
Primary
Concomitant
Atrial Fibrillation 60 Female 225 lb 8/26/2009 United States
Primary
Secondary
Completed Suicide Death 8/31/2009 Physician United States
Primary
Secondary
Skin Ulcer Other Serious 10/1/2007 Female 134 lb 9/1/2009 Lawyer United States
Primary
Secondary
Concomitant
Completed Suicide Death 57 Male 9/4/2009 Physician United States
Primary
Secondary
Tubulointerstitial Nephritis Life Threatening 7/19/2009 Male 208 lb 9/8/2009 Physician Germany
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 8/13/2009 Male 188 lb 9/8/2009 Physician United States
Primary
Concomitant
Completed Suicide Death 87 Female 9/8/2009 Physician United States
Primary
Secondary
Prostate Cancer Other Serious 8/13/2009 Male 188 lb 9/9/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/1/2002 51 Female 232 lb 9/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Completed Suicide Death 87 Female 9/19/2009 Physician United States
Primary
Secondary
Confusional State Required Intervention 11/17/2008 82 Female 134 lb 11/19/2008 Pharmacist United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization Female 9/21/2009 United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 10/2/2009 Lawyer United States
Primary
Secondary
Concomitant
Escherichia Sepsis Hospitalization Female 10/2/2009
Primary
Secondary
Concomitant
Pre-eclampsia Hospitalization 35 Female 354 lb 10/2/2009
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 8/13/2009 Male 188 lb 10/2/2009 Physician United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 4/21/2008 71 Female 137 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 9/22/2009 United States
Primary
Concomitant
Pemphigoid Life Threatening 11/18/2008 Female 194 lb 10/8/2009 Physician United States
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2007 Male 10/8/2009 Consumer
Primary
Concomitant
Sepsis Other Serious 9/18/2009 78 Female 148 lb 10/8/2009 United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 7/19/2009 Male 208 lb 10/12/2009 United States
Primary
Secondary
Concomitant
Pain Hospitalization Female 10/10/2009 United States
Primary
Concomitant
Urinary Tract Infection Death 89 Female 10/10/2009 United States
Primary
Concomitant
Myocardial Infarction Life Threatening 1/1/2001 Female 110 lb 10/20/2009 Consumer United States
Primary
Concomitant
Skin Ulcer Other Serious 10/1/2007 Female 134 lb 10/29/2009 Lawyer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Death 4/22/2009 34 Male 10/26/2009 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Life Threatening 9/1/2009 78 Female 148 lb 11/4/2009 United States
Primary
Secondary
Concomitant
Panic Attack Other Serious 62 Male 229 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Sepsis Life Threatening 9/1/2009 78 Female 148 lb 11/9/2009 United States
Primary
Secondary
Concomitant
Unemployment Other Serious 62 Male 229 lb 11/4/2009 United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 11/9/2009 Lawyer United States
Primary
Concomitant
Pneumonia Hospitalization 11/11/2009 Female 11/19/2009 Consumer United States
Primary
Concomitant
Product Quality Issue Other Serious 12/24/2008 89 Female 11/25/2009 Consumer United States
Primary
Concomitant
Urinary Tract Infection Enterococcal Hospitalization 89 Female 11/16/2009 United States
Primary
Concomitant
Sleep Apnoea Syndrome Death 73 Male 11/18/2009 United States
Primary
Concomitant
Venous Insufficiency Hospitalization 69 Female 11/18/2009 Consumer United States
Primary
Concomitant
Thyroid Disorder Other Serious 4/21/2008 66 Female 137 lb 11/18/2009 United States
Primary
Concomitant
Palpitations Hospitalization 71 Male 11/21/2009 Canada
Primary
Secondary
Syncope Hospitalization 11/24/2009 82 Male 177 lb 11/30/2009 Pharmacist United States
Primary
Secondary
Weight Decreased Hospitalization 9/1/2007 Male 257 lb 12/1/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 1/3/2008 66 Female 161 lb 12/7/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pollakiuria 11/1/2008 76 Male 12/9/2009 Consumer United States
Primary
Concomitant
Renal Tubular Necrosis Disability 76 Female 1/12/2010 Physician United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 7/1/2007 Female 135 lb 1/18/2010 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Hospitalization 25 Female 1/21/2010 Other Health Professional United States
Primary
Secondary
Upper Respiratory Tract Infection Hospitalization 84 Female 1/7/2010 United States
Primary
Concomitant
Vomiting Death 10/1/2007 64 Male 1/21/2010 Lawyer United States
Primary
Concomitant
Cardiac Failure Congestive Other Serious 1/1/2009 71 Male 252 lb 1/22/2010 Physician United States
Primary
Concomitant
Chest Pain Hospitalization 11/30/2009 63 Male 112 lb 5/12/2010 Physician Hong Kong
Primary
Concomitant
Haematuria Other Serious Female 162 lb 6/8/2010 Consumer United States
Primary
Concomitant
Glaucoma Surgery 10/1/2008 62 Female 215 lb 6/16/2010 Consumer United States
Primary
Concomitant
Wound Secretion Other Serious 1/1/2006 60 Male 300 lb 6/17/2010 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Disorder Other Serious 1/1/2008 51 Male 218 lb 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Haematuria Other Serious Female 162 lb 6/17/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/1/2008 82 Male 6/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 60 Male 6/15/2010 United States
Primary
Concomitant
Visual Impairment 6/8/2007 65 Female 119 lb 6/28/2010 Consumer United States
Primary
Concomitant
Inflammation Female 6/29/2010 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 6/21/2010 54 Male 244 lb 7/1/2010 United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Death 7/1/2007 52 Female 135 lb 7/8/2010 Other Health Professional United States
Primary
Concomitant
Sudden Death Death 6/12/2010 72 Male 155 lb 7/1/2010 Physician Canada
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 74 Female 7/1/2010 United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 10/30/2008 56 Male 309 lb 7/12/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2007 66 Female 220 lb 7/14/2010 Consumer United States
Primary
Concomitant
Haematuria Hospitalization 4/20/2010 81 Male 101 lb 7/13/2010 Pharmacist United States
Primary
Concomitant
Sudden Death Death 6/12/2010 72 Male 155 lb 7/14/2010 Physician Canada
Primary
Secondary
Concomitant
Sepsis Other Serious 1/9/2008 79 Female 7/15/2010 Lawyer United States
Primary
Concomitant
Nausea 8/1/2007 55 Female 115 lb 7/15/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 2/8/2008 61 Male 7/19/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 2/26/2008 39 Female 177 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 11/1/2007 65 Female 124 lb 7/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/4/2007 69 Female 326 lb 7/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Syncope Death 6/27/2010 69 Male 8/2/2010 Physician Canada
Primary
Concomitant

Drug Data