Diltiazem combined with Fentanyl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gangrene Other Serious 6/1/2005 Male 140 lb 3/9/2006 Consumer United States
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Fatigue Other Serious 2/6/2006 58 Male 164 lb 2/6/2006 Pharmacist United States
Primary
Concomitant
Nerve Compression Hospitalization 3/1/2006 Female 258 lb 3/30/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 1/10/2006 38 Male 176 lb 4/5/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/13/2006 57 Male 4/25/2006 United States
Primary
Concomitant
Mental Status Changes Hospitalization 11/6/2005 44 Male 11/9/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Hospitalization 3/30/2006 Male 119 lb 5/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2005 45 Female 165 lb 5/22/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 67 Male 139 lb 6/8/2006 Japan
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/3/2006 81 Female 7/26/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 8/1/2006 58 Female 289 lb 11/14/2006 Physician United States
Primary
Concomitant
Bradycardia Hospitalization 1/1/2006 72 Male 12/21/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/30/2007 Male 84 lb 4/4/2007 Other Health Professional Japan
Primary
Secondary
Concomitant
Skin Test Positive Other Serious 61 Male 5/4/2007 Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 8/15/2007 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 1/10/2008 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 1/1/2007 Male 135 lb 2/19/2008 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/28/2008 Male 278 lb 2/22/2008 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 12/15/2007 80 Male 117 lb 3/4/2008 Other Health Professional Italy
Primary
Concomitant
Tracheal Haemorrhage Hospitalization 3/27/2008 79 Female 167 lb 4/3/2008 Pharmacist United States
Primary
Concomitant
Multiple Drug Overdose Death Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Drug Toxicity Death Male 4/15/2008 Other Health Professional United States
Primary
Secondary
Therapeutic Product Contamination Life Threatening 3/19/2008 64 Male 276 lb 5/20/2008 Pharmacist United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 3/27/2008 79 Female 165 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Adverse Drug Reaction Death Male 4/21/2009
Primary
Secondary
Concomitant
Death Death Male 4/21/2009
Primary
Secondary
Concomitant
Vomiting 12/18/2008 32 Female 223 lb 4/30/2009 Physician United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/15/2009 72 Male 282 lb 5/15/2009 Other Health Professional United States
Primary
Concomitant
Respiratory Distress Death 1/18/2009 48 5/21/2009 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Middle Ear Effusion Required Intervention 5/18/2009 Female 107 lb 6/3/2009 Pharmacist United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/7/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 12/10/2008 75 Male 179 lb 8/10/2009 Pharmacist United States
Primary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 8/20/2009 United States
Primary
Concomitant
Skin Ulcer Other Serious 10/1/2007 Female 134 lb 9/1/2009 Lawyer United States
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 6/27/2009 Male 145 lb 9/2/2009 United States
Primary
Concomitant
Respiratory Depression Other Serious 6/25/2009 Male 9/8/2009 Physician Switzerland
Primary
Secondary
Oedema Peripheral Hospitalization Female 145 lb 9/14/2009 Consumer United States
Primary
Concomitant
Nocturia Other Serious 8/14/2009 Female 10/5/2009 Physician Australia
Primary
Concomitant
Platelet Count Decreased Other Serious 8/1/2008 78 Male 137 lb 1/14/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Psoriasis Other Serious 1/1/2009 65 Male 265 lb 4/9/2010 Consumer United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 5/7/2010 Consumer United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 6/14/2010 Lawyer United States
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 6/22/2010 Consumer United States
Primary
Concomitant
Visual Field Defect Other Serious 8/1/2001 63 Male 6/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Intestinal Ischaemia Death 5/7/2010 60 Female 138 lb 7/1/2010 Physician Canada
Primary
Concomitant
Vomiting Other Serious 6/2/2010 72 Male 7/2/2010 Canada
Primary
Concomitant
Spondylitis Other Serious 1/1/2009 65 Male 265 lb 7/8/2010 Consumer United States
Primary
Concomitant
Vascular Cauterisation Other Serious 5/19/2010 68 Female 189 lb 7/30/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 8/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 9/16/2007 49 Male 303 lb 8/17/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weaning Failure Other Serious 12/1/2007 66 Male 10/19/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2007 64 Female 10/28/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious Female 11/5/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 12/24/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 85 Male 12/29/2010 Other Health Professional United States
Primary
Concomitant
Interacting
White Blood Cell Count Increased Life Threatening 55 Male 12/22/2010 Physician United States
Primary
Secondary
Concomitant
Death Death Female 1/6/2011 Canada
Primary
Concomitant
Hallucination Hospitalization 85 Male 1/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Rhinorrhoea Other Serious Female 1/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pubis Fracture Hospitalization 12/23/2010 77 Female 1/28/2011 Consumer Netherlands
Primary
Concomitant
Breast Cancer Life Threatening 5/25/2007 64 Female 97 lb 2/4/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 55 Male 1/25/2011 Physician United States
Primary
Secondary
Clostridium Difficile Colitis Other Serious 85 Male 1/25/2011 Physician United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Other Serious 12/23/2010 77 Female 3/1/2011 Consumer Netherlands
Primary
Concomitant
Cystitis Haemorrhagic Death 10/14/2010 49 Male 2/23/2011 Physician United States
Primary
Concomitant
Renal Failure Other Serious 8/9/2004 74 Male 183 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 5/1/2005 65 Male 130 lb 4/18/2011 Other Health Professional United States
Primary
Concomitant
Shock Other Serious 1/1/2011 72 Female 4/26/2011 Physician United States
Primary
Concomitant
Unevaluable Event Other Serious 70 Male 198 lb 4/28/2011 Consumer United States
Primary
Concomitant
Hypokinesia Other Serious Male 154 lb 5/4/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 10/11/2005 80 Female 121 lb 5/6/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 48 Female 250 lb 5/14/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 70 Male 198 lb 5/19/2011 Other Health Professional United States
Primary
Concomitant
Nervousness Other Serious 48 Female 250 lb 5/20/2011 Physician United States
Primary
Concomitant
Injury Other Serious 51 Female 238 lb 5/21/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 5/24/2004 60 Male 256 lb 5/25/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 74 Female 150 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 8/27/2002 81 Female 161 lb 5/26/2011 Consumer United States
Primary
Concomitant
Death Hospitalization 10/1/2006 70 Male 295 lb 5/28/2011 Consumer United States
Primary
Concomitant
Cardiogenic Shock Death 7/17/2004 72 Female 165 lb 6/1/2011 Consumer United States
Primary
Concomitant
Cellulitis Death 9/10/2002 59 Male 230 lb 6/7/2011 Physician United States
Primary
Secondary
Concomitant
Pubis Fracture Other Serious 12/23/2010 77 Female 6/9/2011 Physician Netherlands
Primary
Concomitant
Depressed Level Of Consciousness Other Serious 84 Female 6/14/2011 Consumer Canada
Primary
Secondary
Concomitant
Fear Death 8/9/2004 74 Male 220 lb 6/20/2011 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 1/1/2006 67 Female 6/27/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 5/10/2005 77 Female 170 lb 6/22/2011 Other Health Professional United States
Primary
Concomitant
Dry Mouth Hospitalization 9/10/2002 59 Male 230 lb 6/28/2011 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 8/21/2003 69 Male 226 lb 7/6/2011 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 5/1/2011 28 Female 7/8/2011 Physician Romania
Primary
Concomitant
Systemic Lupus Erythematosus Other Serious 1/1/2006 67 Female 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 73 Female 139 lb 7/11/2011 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 10/7/2010 49 Male 6/29/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Other Serious 7/1/2011 55 Female 7/15/2011 Consumer United States
Primary
Concomitant
Lung Neoplasm Other Serious 1/1/2011 61 Male 210 lb 7/11/2011 Consumer United States
Primary
Secondary
Concomitant
Anhedonia Other Serious 10/1/2001 58 Male 205 lb 7/29/2011 Lawyer United States
Primary
Concomitant
Renal Injury Other Serious 1/1/2003 76 Female 160 lb 8/8/2011 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 10/1/2001 58 Male 205 lb 8/19/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Fear Other Serious 10/1/2001 59 Male 205 lb 8/24/2011 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased Other Serious 8/4/2011 70 Female 8/24/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 10/1/2001 59 Male 205 lb 8/24/2011 Physician United States
Primary
Secondary
Concomitant
Abdominal Pain Upper Hospitalization 1/1/2002 75 Female 138 lb 9/19/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Infectious Peritonitis Death 5/4/2010 60 Female 138 lb 9/26/2011 Physician Canada
Primary
Concomitant
Anxiety Other Serious 10/1/2001 59 Male 205 lb 9/27/2011 Other Health Professional United States
Primary
Concomitant
Infectious Peritonitis Death 5/4/2010 60 Female 138 lb 9/26/2011 Physician Canada
Primary
Concomitant
Diarrhoea Death 9/7/2010 69 Female 11/11/2011 Other Health Professional United States
Primary
Concomitant
Disorientation Other Serious 79 Female 11/15/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Metastatic Gastric Cancer Death Male 4/17/2012 Other Health Professional United States
Primary
Concomitant
Pain In Extremity 4/1/2012 72 Female 106 lb 6/4/2012 Consumer United States
Primary
Concomitant
Hyperhidrosis Hospitalization 4/1/2012 59 Male 170 lb 5/25/2012 Physician United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/1/2012 72 Female 104 lb 6/8/2012 Consumer United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Life Threatening 39 Male 5/30/2012 Japan
Primary
Secondary
Concomitant
Inflammation Hospitalization Male 153 lb 6/13/2012 Consumer United States
Primary
Concomitant
Asthenia Hospitalization 6/17/2011 59 Male 10/4/2011 Physician United States
Primary
Concomitant
Diarrhoea Other Serious 3/1/2012 65 Female 6/14/2012 United States
Primary
Concomitant
Back Pain Hospitalization 4/1/2012 59 Male 170 lb 6/10/2012 Physician United States
Primary
Concomitant
Erythema Female 7/16/2012 Consumer United States
Primary
Concomitant
Dyspepsia Other Serious 79 Female 8/22/2012 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Life Threatening 4/15/2012 65 Female 204 lb 8/15/2012 Pharmacist United States
Primary
Concomitant
Spinal Disorder Other Serious 6/26/2012 89 Female 1/28/2013 Consumer Ca
Primary
Concomitant
Transient Ischaemic Attack Hospitalization Female 135 lb 10/19/2012 Lawyer Us
Primary
Concomitant
Vertigo Hospitalization 2006 69 Female 3/26/2013 Us
Primary
Secondary
Concomitant
Vertigo Other Serious 2006 69 Female 9/20/2012 Physician Us
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/2011 86 Female 1/14/2013 Physician Us
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 39 Male 220 lb 9/12/2012 Other Health Professional Jp
Primary
Secondary
Interacting
Venous Thrombosis Limb Other Serious 8/13/2011 75 Female 110 lb 3/11/2013 Consumer Us
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/2012 59 Male 170 lb 7/22/2013 Physician Us
Primary
Concomitant
Tremor Other Serious 79 Female 9/19/2012 Consumer Us
Primary
Secondary
Concomitant
Hyperthermia Malignant Hospitalization 27 Male 154 lb 9/2/2012 Pharmacist Us
Primary
Concomitant
Vomiting Other Serious 2/2/2011 49 Female 119 lb 9/17/2012 Physician Us
Primary
Concomitant
Vomiting Hospitalization 11/16/2010 66 Female 119 lb 9/27/2012 Physician Ca
Primary
Secondary
Concomitant
Mental Status Changes Death 10/2010 81 Female 181 lb 7/30/2013 Consumer Us
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 5/26/2011 32 Female 5/2/2013 Lawyer Ca
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 9/25/2012 59 Female 227 lb 10/22/2012 Physician Gb
Primary
Concomitant
Hypotension Other Serious 9/25/2012 59 Female 227 lb 10/16/2012 Physician Gb
Primary
Concomitant
Blood Creatine Phosphokinase Increased 10/18/2012 62 Male 176 lb 10/25/2012 Physician Us
Primary
Secondary
Concomitant
Thrombosis Other Serious 5/3/2010 45 Male 303 lb 11/26/2012 Us
Primary
Concomitant
Death Death Female 11/20/2012 Consumer Us
Primary
Concomitant
Blood Creatine Phosphokinase Increased 10/18/2012 62 Male 176 lb 10/25/2012 Physician Us
Primary
Concomitant
Pneumonia Other Serious 10/21/2012 58 Female 198 lb 7/8/2013 Physician Us
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 6/25/2012 54 Male 150 lb 1/30/2013 Physician Us
Primary
Secondary
Concomitant
Throat Tightness Other Serious 2012 87 Female 166 lb 2/26/2013 Physician Us
Primary
Concomitant
Pulmonary Oedema Death 68 Male 6/15/2013 Other Health Professional Fi
Primary
Secondary
Concomitant
Headache Other Serious 4/7/2013 56 Female 5/22/2013 Consumer Ca
Primary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 NotSpecified 5/24/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Tachycardia Required Intervention 5/22/2013 82 Female 199 lb 5/28/2013 Other Health Professional Us
Primary
Secondary
Concomitant
Respiratory Disorder Death 5/4/2013 77 Male 147 lb 6/4/2013 Other Health Professional Us
Primary
Concomitant

Drug Data