Dilantin combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Simple Partial Seizures Other Serious 68 Female 140 lb 1/27/2006 United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious Female 120 lb 4/7/2006 United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 4/10/2006 Physician United States
Primary
Concomitant
Skin Exfoliation Other Serious 9/13/2005 34 Female 108 lb Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2006 46 Male 4/20/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 6/30/2006 Male 207 lb 7/6/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Spina Bifida Other Serious Male 7 lb 7/20/2006 Consumer United States
Primary
Concomitant
Spina Bifida Occulta Required Intervention 8/1/2005 Male 7 lb 7/28/2006 United States
Primary
Secondary
Spina Bifida Occulta Other Serious Male 7 lb 8/7/2006 Consumer United States
Primary
Secondary
Thrombocytopenia Other Serious 1/1/2006 58 Female 168 lb 8/4/2006 Physician United States
Primary
Concomitant
Drug Interaction Other Serious Female 8/21/2006 Physician United States
Primary
Interacting
Mobility Decreased Other Serious 7/1/2006 61 Female 8/30/2006 Consumer Canada
Primary
Concomitant
Vision Blurred Other Serious 1/1/1998 69 Male 160 lb 9/8/2006 United States
Primary
Secondary
International Normalised Ratio Decreased Other Serious 7/1/2006 Male 295 lb 9/27/2006 Consumer United States
Primary
Concomitant
Suicide Attempt Required Intervention 6/10/1998 18 Female 10/5/2006 United States
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 9/26/2005 32 Female 136 lb 12/1/2005 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/22/2006 23 Female 165 lb 10/5/2006 United States
Primary
Concomitant
Status Epilepticus Other Serious 57 Female 132 lb 10/16/2006 Physician United States
Primary
Secondary
Concomitant
Tooth Deposit Other Serious 68 Female 151 lb 10/17/2006 United States
Primary
Secondary
Concomitant
Oral Intake Reduced Hospitalization 7/22/2006 22 Female 165 lb 10/13/2006 United States
Primary
Concomitant
Dyspnoea 2/5/2006 50 Female 284 lb 10/30/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 57 Female 132 lb 11/3/2006 Physician United States
Primary
Secondary
Concomitant
Hypersensitivity Hospitalization 2/9/2006 58 Male 210 lb 8/18/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Other Serious 4/21/2005 40 Female 154 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 10/1/2004 21 Male 180 lb 8/18/2006 Physician United States
Primary
Concomitant
Leukopenia Hospitalization 10/21/2005 62 Female 110 lb 8/18/2006 Pharmacist United States
Primary
Concomitant
Rhinorrhoea Other Serious 10/7/2005 40 Female 222 lb 8/18/2006 Consumer United States
Primary
Concomitant
Panic Attack 12/6/2006 47 Female 1/5/2007 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2007 Female 230 lb 1/10/2007 Other Health Professional United States
Primary
Secondary
Pulmonary Embolism Hospitalization 12/5/2006 36 Female 1/12/2007 Pharmacist United States
Primary
Concomitant
Drug Level Decreased Other Serious 1/12/2007 34 Female 1/19/2007 Consumer United States
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2005 Female 110 lb 1/31/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Other Serious 54 Female 11/13/2006 Consumer United States
Primary
Concomitant
Rash Other Serious 3/18/2007 10 Female 68 lb 4/9/2007 Consumer Thailand
Primary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 4/27/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2007 Female 5/2/2007 Consumer United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 1/1/2001 46 Male 149 lb 5/7/2007 Physician United States
Primary
Concomitant
Spina Bifida Occulta Other Serious Male 7 lb 5/11/2007 Consumer United States
Primary
Concomitant
Tethered Cord Syndrome Other Serious Male 7 lb 5/18/2007 Other Health Professional United States
Primary
Secondary
Spinal Cord Compression Other Serious 8/1/2005 Male 7 lb 5/21/2007 Other Health Professional United States
Primary
Secondary
Rash 1/22/2007 64 Female 263 lb 5/17/2007 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 154 lb 6/18/2007 Consumer United States
Primary
Secondary
Concomitant
Interacting
Incoherent Other Serious 12/25/2006 Male 230 lb 7/12/2007 Consumer United States
Primary
Concomitant
Drug Hypersensitivity Other Serious 8/9/2007 Female 228 lb 8/28/2007 Consumer United States
Primary
Secondary
Concomitant
Myelopathy Other Serious 44 Male 122 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Lumbar Puncture Other Serious 8/9/2007 Female 228 lb 8/31/2007 Consumer United States
Primary
Secondary
Concomitant
Lumbar Puncture Other Serious 8/9/2007 Female 228 lb 9/6/2007 United States
Primary
Secondary
Concomitant
Oculogyric Crisis Other Serious 50 Male 9/7/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Oculogyric Crisis Other Serious 50 Male 9/13/2007 Consumer Taiwan, Province Of China
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 9/25/2007 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2006 14 Female 125 lb 9/26/2007 Physician United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 3/24/2007 26 Female 10/5/2007 Consumer United States
Primary
Secondary
Concomitant
Pregnancy On Oral Contraceptive Other Serious 3/24/2007 26 Female 10/5/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2006 14 Female 125 lb 10/2/2007 Physician United States
Primary
Secondary
Concomitant
Hypoaesthesia Other Serious 51 Female 11/6/2007 Consumer Australia
Primary
Concomitant
Weight Increased Other Serious 8/18/2007 Female 230 lb 11/19/2007 Consumer United States
Primary
Concomitant
Tremor Other Serious 3/27/2002 44 Female 250 lb 11/26/2007 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 11/26/2007 47 Male 209 lb 11/27/2007 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 12/7/2007 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 4/20/2007 27 Female 10/9/2007 Consumer United States
Primary
Concomitant
Migraine Other Serious 9/20/2007 51 Female 12/18/2007 Physician Australia
Primary
Concomitant
Convulsion Other Serious 1/1/2007 Female 12/19/2007 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 12/26/2007 Lawyer United States
Primary
Concomitant
Tooth Erosion Other Serious 1/31/2008 Female 165 lb 2/27/2008 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/18/2007 Male 7/23/2007 Pharmacist United States
Primary
Concomitant
Tooth Erosion Other Serious 1/31/2008 Female 165 lb 3/5/2008 Consumer United States
Primary
Concomitant
Lumbar Puncture Other Serious 8/9/2007 Female 227 lb 3/6/2008 United States
Primary
Secondary
Concomitant
Rash Generalised 9/25/2007 35 Female 220 lb 9/26/2007 Consumer United States
Primary
Concomitant
Influenza Like Illness Other Serious 2/4/2008 18 Male 236 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Nervousness Other Serious 3/1/2008 Female 105 lb 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Hepatic Failure Other Serious 12/1/2006 Male 4/7/2008 Lawyer United States
Primary
Concomitant
Convulsion Other Serious 2/1/2008 Female 150 lb 4/7/2008 Consumer United States
Primary
Concomitant
Lumbar Puncture Other Serious 1/1/2007 Female 227 lb 4/18/2008 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 12/1/2007 Female 115 lb 4/29/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2007 Female 115 lb 5/7/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 12/1/2007 Female 115 lb 5/13/2008 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 2/4/2008 18 Male 236 lb 5/15/2008 Other Health Professional United States
Primary
Concomitant
Surgery Other Serious 4/1/2008 Male 5/16/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Sternal Fracture Hospitalization 12/1/2007 Female 160 lb 5/30/2008 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 162 lb 6/2/2008 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 6/12/2008 Lawyer United States
Primary
Secondary
Concomitant
Oedema Peripheral 5/5/2008 57 Female 240 lb 6/18/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 6/20/2008 Lawyer United States
Primary
Secondary
Concomitant
Convulsion Other Serious Male 7/14/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious Female 8/8/2008 Consumer United States
Primary
Secondary
Toxic Epidermal Necrolysis Other Serious 10/17/2000 Male 134 lb 8/15/2008 Lawyer United States
Primary
Concomitant
Speech Disorder Hospitalization 7/22/2006 22 Female 165 lb 8/7/2008 Consumer United States
Primary
Concomitant
Photopsia Other Serious 5/1/2008 Female 125 lb 8/26/2008 Consumer United States
Primary
Concomitant
Rash Other Serious 4/27/2008 39 Female 228 lb 8/22/2008 Consumer United States
Primary
Concomitant
Sedation Other Serious 5/1/2007 Female 191 lb 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Interacting
Viral Infection Other Serious 3/1/2008 Female 290 lb 9/3/2008 Lawyer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 9/22/2008 Lawyer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 Female 134 lb 9/24/2008 Consumer United States
Primary
Secondary
Weight Increased Other Serious 10/1/2007 Female 10/10/2008 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 Female 134 lb 10/15/2008 Consumer United States
Primary
Secondary
Tremor Other Serious 3/27/2002 44 Female 250 lb 11/3/2008 United States
Primary
Concomitant
Tongue Blistering Other Serious 1/1/1999 Female 163 lb 11/18/2008 Consumer United States
Primary
Secondary
Concomitant
Vomiting 1/1/2008 29 Female 11/14/2008 United States
Primary
Secondary
Concomitant
Nausea Other Serious 1/1/2008 53 Female 12/4/2008 Consumer United States
Primary
Secondary
Concomitant
Off Label Use Other Serious 6/1/2008 26 Male 1/16/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Hospitalization Female 2/27/2009 Consumer United States
Primary
Concomitant
Paraesthesia 5/1/2008 51 Female 201 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 3/1/2008 29 Female 130 lb 2/11/2009 Consumer United States
Primary
Concomitant
Convulsion Other Serious 11/1/2007 40 Female 3/18/2009 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 3/31/2009 Lawyer United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 3/1/2008 29 Female 130 lb 4/7/2009 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 4/16/2009 Lawyer United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 11/10/1999 47 Male 158 lb 5/21/2009 United States
Primary
Concomitant
Convulsion Hospitalization 3/1/2008 29 Female 130 lb 5/13/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Death 12/21/2008 45 Female 104 lb 6/8/2009 Pharmacist United States
Primary
Concomitant
Drug Ineffective 63 Female 6/22/2009 Consumer United States
Primary
Concomitant
Appendicectomy Hospitalization 4/4/2009 Male 6/27/2009 Physician Korea, Republic Of
Primary
Concomitant
Tongue Blistering Other Serious 1/1/1999 Female 163 lb 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/1998 34 Female 236 lb 7/13/2009 United States
Primary
Concomitant
Somnolence Other Serious 1/1/2005 33 Female 128 lb 7/8/2009 Consumer United States
Primary
Concomitant
Obesity Other Serious 1/1/2003 37 Female 199 lb 7/15/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/1998 34 Female 236 lb 7/17/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/17/2005 20 Female 275 lb 7/23/2009 United States
Primary
Concomitant
Somnolence Other Serious 3/1/2008 Male 160 lb 7/30/2009 Consumer United States
Primary
Secondary
Medication Error Other Serious Male 8/20/2009 United States
Primary
Concomitant
Tremor Other Serious 56 8/20/2009 Consumer Australia
Primary
Concomitant
Vomiting Other Serious 12/13/2001 21 Female 220 lb 9/15/2009 United States
Primary
Concomitant
Weight Increased 1/1/2005 25 Female 312 lb 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 4/10/2006 38 Female 170 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2003 27 Female 157 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/2/2004 12 Female 225 lb 9/23/2009 United States
Primary
Concomitant
Product Substitution Issue Required Intervention 58 Male 9/26/2009 Pharmacist United States
Primary
Concomitant
Petit Mal Epilepsy Other Serious Female 137 lb 10/1/2009 Consumer United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 1/1/2009 Female 137 lb 10/2/2009 Consumer United States
Primary
Concomitant
Motor Dysfunction Other Serious 8/6/2009 46 Male 230 lb 10/14/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2008 Female 10/19/2009 Consumer United States
Primary
Concomitant
Tremor Other Serious 10/5/2009 Female 10/22/2009 Other Health Professional United States
Primary
Concomitant
Purple Glove Syndrome Other Serious 8 Male 84 lb 11/12/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Syndactyly Other Serious 12/27/2009 Other Health Professional United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 25 Female 12/27/2009 Other Health Professional United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 9/22/2009 25 Female 12/30/2009 Consumer United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 25 Female 12/31/2009 Other Health Professional United States
Primary
Secondary
Red Blood Cell Count Decreased Other Serious 5/13/2009 Female 1/12/2010 Consumer United States
Primary
Secondary
Concomitant
Multiple Congenital Abnormalities Other Serious 1/15/2010 Other Health Professional United States
Primary
Secondary
Syndactyly Other Serious 9/22/2009 1/20/2010 Consumer United States
Primary
Secondary
Drug Exposure During Pregnancy Other Serious 9/22/2009 25 Female 1/20/2010 Consumer United States
Primary
Secondary
Tonsillitis 5/1/2009 29 Female 1/24/2010 Consumer United States
Primary
Concomitant
Pyrexia Life Threatening 10/29/2002 19 Male 152 lb 1/21/2010 Physician United States
Primary
Secondary
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 2/18/2010 Physician United States
Primary
Interacting
Myalgia Hospitalization 7/9/2003 Male 2/19/2010 United States
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Other Serious 12/9/2009 19 Female 151 lb 3/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious 9/22/2009 25 Female 3/29/2010 Consumer United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 3/27/2002 44 Female 250 lb 4/19/2010 United States
Primary
Concomitant
Tremor Hospitalization 4/10/2010 37 Female 5/10/2010 Other Health Professional United States
Primary
Secondary
Death Death 4/21/2010 17 Female 6/2/2010 Other Health Professional United States
Primary
Concomitant

Drug Data