Digoxin combined with Zocor

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rhabdomyolysis Other Serious 11/24/2005 70 Male 220 lb 1/9/2006 Physician United States
Primary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 1/11/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/1/2000 58 Female 181 lb 1/17/2006 Physician United States
Primary
Concomitant
Phlebitis Deep Other Serious 1/28/2005 Male 154 lb 1/19/2006 Physician France
Primary
Concomitant
Neoplasm Malignant Hospitalization 3/1/2000 48 Female 150 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Rash Hospitalization 1/1/2001 71 Male 236 lb 1/24/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 69 Male 1/26/2006 United States
Primary
Concomitant
Vomiting Other Serious 78 Male 170 lb 1/25/2006 United States
Primary
Concomitant
Rash 88 Male 138 lb 12/7/2005 Consumer United States
Primary
Concomitant
Vomiting Other Serious 78 Male 170 lb 1/31/2006 United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2005 81 Male 120 lb 2/2/2006 Physician United States
Primary
Concomitant
Fall Other Serious 1/12/2006 85 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Malaise Other Serious 1/1/2003 70 Male 2/8/2006 United States
Primary
Concomitant
Vomiting Other Serious 5/3/2004 73 Male 184 lb 2/13/2006 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Hospitalization 9/2/2005 Female 98 lb 11/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 5/2/2005 Male 214 lb 12/8/2005 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2002 65 Male 170 lb 2/21/2006 Physician United States
Primary
Concomitant
Dysgeusia 10/1/2005 78 Male 200 lb 1/5/2006 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 7/1/2002 65 Male 220 lb 2/23/2006 Physician United States
Primary
Concomitant
Somnolence Hospitalization 11/3/2005 84 Female 2/24/2006 Other Health Professional France
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 67 Male 209 lb 2/24/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2005 78 Male 156 lb 1/20/2006 United States
Primary
Concomitant
Urine Flow Decreased 1/3/2006 72 Male 2/27/2006 Consumer United States
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Death Death 2/12/2006 Female 205 lb 3/1/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 79 Male 180 lb 2/22/2006 Physician United States
Primary
Secondary
Concomitant
Vascular Dementia Hospitalization 11/3/2005 84 Female 3/7/2006 Other Health Professional France
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/20/2003 79 Male 225 lb 3/9/2006 Physician United States
Primary
Concomitant
Vascular Bypass Graft Other Serious 2/10/2006 67 Male 3/8/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2002 71 Male 220 lb 3/13/2006 Lawyer United States
Primary
Concomitant
Rhabdomyolysis Required Intervention 11/8/2005 69 Male 195 lb 3/8/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 2/18/2006 72 Female 152 lb 2/28/2006 Physician United States
Primary
Concomitant
Chronic Obstructive Pulmonary Disease Hospitalization 2/25/2006 Male 88 lb 3/16/2006 Consumer United States
Primary
Concomitant
Death Death 2/12/2006 Female 205 lb 3/20/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Required Intervention 2/18/2006 75 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rales Hospitalization 11/1/2003 80 Male 161 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/2002 79 Male 181 lb 3/21/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/1/2005 69 Male 3/20/2006 Physician United States
Primary
Concomitant
Oedema Peripheral Hospitalization 10/15/2005 71 Male 3/29/2006 Consumer France
Primary
Concomitant
Sudden Death Death 5/1/2005 88 Male 3/14/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2005 61 Female 168 lb 3/30/2006 Other Health Professional Australia
Primary
Concomitant
Thrombosis Other Serious 5/31/2004 Male 165 lb 3/31/2006 Lawyer United States
Primary
Concomitant
Overdose Other Serious 12/18/2000 71 Female 146 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Rash Generalised 11/1/2005 77 Female 180 lb 1/20/2006 Consumer United States
Primary
Concomitant
Troponin Increased Hospitalization 10/5/2003 73 Female 4/7/2006 Physician Australia
Primary
Secondary
Concomitant
Sleep Apnoea Syndrome Other Serious 5/1/2000 53 Female 181 lb 4/7/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Loss Of Consciousness Life Threatening 11/13/2005 59 Male 4/10/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 2/24/2005 80 Female 4/10/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 5/29/2000 71 Female 146 lb 4/19/2006 Physician Puerto Rico
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 5/3/2004 73 Male 184 lb 4/20/2006 Physician United States
Primary
Secondary
Concomitant
Myalgia Life Threatening 8/1/2003 75 Female 2/21/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 3/11/2005 79 Female 119 lb 2/21/2006 Physician United States
Primary
Concomitant
Epistaxis Hospitalization 2/2/2006 54 Female 179 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea 2/16/2006 50 Female 280 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 7/13/2005 78 Male 2/21/2006 United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Death 10/2/2001 59 Female 115 lb 4/28/2006 Physician United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/25/2006 81 Male 163 lb 5/2/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 1/1/2000 58 Female 181 lb 5/10/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 12/14/2002 67 Female 220 lb 5/11/2006 Physician United States
Primary
Concomitant
Sudden Cardiac Death Death 3/24/2003 63 Male 298 lb 5/11/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Pain Hospitalization 1/1/2003 65 Female 161 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Xanthoma Other Serious 1/1/2001 57 Male 181 lb 5/17/2006 Physician United States
Primary
Concomitant
Surgery Other Serious 3/25/2004 78 Female 145 lb 5/11/2006 Other Health Professional United States
Primary
Concomitant
Metabolic Acidosis Hospitalization 3/10/2006 89 Male Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 3/31/2006 Female 5/4/2006 Consumer United States
Primary
Concomitant
Heart Rate Irregular Other Serious 81 Female 5/17/2006 United States
Primary
Secondary
Concomitant
Mouth Haemorrhage Hospitalization 3/5/2006 84 Male 210 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
Urinary Retention Other Serious 5/20/2006 82 Male 6/7/2006 Physician United States
Primary
Concomitant
Pneumonia Death 2/12/2006 70 Female 205 lb 6/13/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/5/2006 58 Male 174 lb 6/7/2006 Pharmacist United States
Primary
Concomitant
Muscular Weakness Other Serious 12/1/2005 60 Female 320 lb 4/20/2006 Consumer United States
Primary
Concomitant
Rash Maculo-papular Other Serious 6/7/2006 66 Female 150 lb 6/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 49 Female 3/17/2006 Other Health Professional United States
Primary
Concomitant
Syncope 1/7/2006 79 Female 198 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Insomnia 11/1/2005 42 Female 170 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Blood Creatinine Increased 5/10/2006 71 Female 6/30/2006 Consumer United States
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Glycosylated Haemoglobin Increased 1/5/2006 80 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 7/1/2006 Male 7/31/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased 3/1/2006 74 Male 134 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Fluctuation 40 Male 311 lb 8/1/2006 Consumer United States
Primary
Concomitant
Medication Residue 64 Female 181 lb 8/14/2006 Consumer United States
Primary
Concomitant
Marrow Hyperplasia Hospitalization 7/5/2006 79 Male 8/15/2006 Other Health Professional France
Primary
Secondary
Ischaemic Cardiomyopathy Hospitalization 4/12/1999 48 Male 8/15/2006 France
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/14/1998 73 Male 8/15/2006 France
Primary
Concomitant
Hypotension Hospitalization 3/19/2006 72 Male 219 lb 8/7/2006 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 11/15/2002 75 Male 8/18/2006 Physician United States
Primary
Concomitant
Pericarditis Other Serious 1/1/2005 Male 237 lb 8/25/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Required Intervention 1/1/2002 75 Male 8/21/2006 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Other Serious 7/1/2006 Male 284 lb 8/29/2006 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 1/1/2002 75 Male 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2002 75 Male 9/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 8/26/2006 89 Female 9/5/2006 Physician United States
Primary
Concomitant
Cardiac Arrest Death 2/18/2005 69 Female 7/14/2006 Physician United States
Primary
Concomitant
Weight Increased 6/1/2006 62 Female 9/15/2006 Consumer United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 7/5/2006 79 Male 9/22/2006 Other Health Professional France
Primary
Secondary
White Blood Cell Count Increased Death 8/26/2006 89 Female 9/25/2006 Other Health Professional United States
Primary
Concomitant
Nodal Arrhythmia Life Threatening 4/26/2006 Female 205 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Mental Status Changes Hospitalization 9/25/2006 84 Male Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 10/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Hospitalization 5/1/2006 59 Female 10/12/2006 Physician United States
Primary
Concomitant
Urticaria Generalised Other Serious 7/2/2006 80 Male 8/10/2006 Consumer United States
Primary
Concomitant
Weight Decreased 1/1/2006 81 Female 8/22/2006 United States
Primary
Concomitant
Eructation 4/1/2006 79 Male 8/22/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Retention Other Serious 10/12/2006 73 Female 10/26/2006 United States
Primary
Concomitant
Death Death 9/1/2006 84 Male 10/26/2006 Other Health Professional United States
Primary
Concomitant
Condition Aggravated Hospitalization 2/25/2006 Male 88 lb 11/8/2006 Consumer United States
Primary
Concomitant
Death Death 9/1/2006 84 Male 11/1/2006 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/15/2006 71 Male 11/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Hospitalization 6/1/2006 81 Male 11/13/2006 Consumer United States
Primary
Concomitant
Stomach Discomfort 82 Female 11/13/2006 Consumer United States
Primary
Concomitant
Dyspnoea 1/1/2003 69 Male 11/13/2006 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 73 Female 11/6/2006 Consumer United States
Primary
Concomitant
Haematoma Hospitalization 9/17/2006 76 Female 97 lb 11/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Neutropenia Other Serious 5/23/2005 75 Male 11/15/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/21/2005 74 Male 11/15/2006 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 8/26/2006 89 Female 11/27/2006 Physician United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 12/26/2003 65 Female 11/29/2006 Pharmacist United States
Primary
Concomitant
Skin Necrosis Hospitalization 7/1/2003 75 Female 11/29/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Disability 8/1/2006 90 Female 12/13/2006 Consumer United States
Primary
Concomitant
Malaise Death 11/27/2006 73 Male 287 lb 12/1/2006 Physician United States
Primary
Concomitant
Hypotension Hospitalization 9/1/2006 Male 172 lb 12/14/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Life Threatening 11/7/2006 77 Male 155 lb 12/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Malaise Death 11/27/2006 73 Male 287 lb 12/14/2006 Physician United States
Primary
Secondary
Concomitant
Malaise 10/1/2006 Male 12/22/2006 Consumer United States
Primary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 12/27/2006 Other Health Professional United States
Primary
Concomitant
Seborrhoea Death 11/27/2006 73 Male 187 lb 12/18/2006 Physician United States
Primary
Secondary
Concomitant
Blood Pressure Systolic Increased 5/16/2006 78 Male 12/28/2006 Consumer United States
Primary
Concomitant
Drug Ineffective Male 12/28/2006 Consumer United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 1/19/2005 58 Male 1/3/2007 Pharmacist United States
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Hospitalization 8/26/2006 77 Male 130 lb 10/26/2006 Pharmacist United States
Primary
Concomitant
Ejection Fraction Decreased Other Serious 12/1/2006 64 Male 1/23/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/17/2006 Female 125 lb 3/28/2006 Pharmacist United States
Primary
Concomitant
Vertigo Hospitalization 7/1/2000 67 Female 1/30/2007 Physician United States
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2005 Male 1/30/2007 Physician United States
Primary
Concomitant
Colitis Collagenous Hospitalization 82 Female 2/2/2007 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/2/2007 Other Health Professional United States
Primary
Concomitant
Eructation 4/1/2006 79 Male 11/21/2006 United States
Primary
Concomitant
Weight Decreased 1/1/2006 81 Female 11/21/2006 United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/12/2007 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 10/20/2006 63 Male 2/16/2007 Pharmacist United States
Primary
Concomitant

Drug Data