Digoxin combined with Warfarin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Function Abnormal Other Serious 10/1/2005 71 Male 1/3/2006 Physician Japan
Primary
Concomitant
Haemarthrosis Hospitalization 6/6/2004 Female 1/4/2006 France
Primary
Concomitant
Renal Failure Acute Hospitalization 3/20/2003 Female 1/4/2006 Australia
Primary
Concomitant
Vomiting Hospitalization 1/3/2006 United Kingdom
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 85 Female 1/5/2006 Physician United States
Primary
Secondary
Ventricular Dysfunction Hospitalization 1/1/2000 58 Female 181 lb 1/17/2006 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 5/15/2005 68 Male 218 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/1/2004 73 Male 185 lb 1/18/2006 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Required Intervention 9/6/2005 50 Male 194 lb 1/3/2006 United States
Primary
Concomitant
Respiratory Distress Life Threatening 9/15/2005 81 Male 170 lb 11/11/2005 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious Male 1/17/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/9/2006 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Other Serious 9/22/2003 87 Female 95 lb 1/23/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 82 Male 256 lb 1/23/2006 Lawyer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/1/2001 73 Male 185 lb 1/23/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 66 Male 211 lb 1/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 1/3/2006 81 Male 176 lb 1/24/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 1/1/2000 83 Female 99 lb 1/25/2006 United Kingdom
Primary
Concomitant
Sepsis Death 12/1/2005 60 Male 187 lb 1/26/2006 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 1/4/2006 70 Female 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 10/20/2005 71 Male 11/5/2005 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/9/2004 Male 157 lb 2/9/2006 United Kingdom
Primary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Malaise Other Serious 12/18/2005 57 Female 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 2/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 2/9/2006 Physician United Kingdom
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Renal Failure Acute Death 79 Female 2/13/2006 Canada
Primary
Concomitant
Oliguria Other Serious 12/7/2005 61 Male 291 lb 2/21/2006 Physician Canada
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/1/2005 Male 212 lb 2/21/2006 Physician United Kingdom
Primary
Concomitant
Paradoxical Drug Reaction 10/11/2005 81 Female 150 lb 1/5/2006 Consumer United States
Primary
Concomitant
Somnolence 5/22/2005 82 Male 172 lb 1/5/2006 United States
Primary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Drug Withdrawal Syndrome Other Serious 12/8/2005 84 Female 2/10/2006 United Kingdom
Primary
Concomitant
Mouth Haemorrhage Hospitalization 2/12/2006 Male 3/2/2006 Physician Japan
Primary
Concomitant
Interacting
Ischaemic Stroke Hospitalization 1/29/2003 89 Male 141 lb 3/3/2006 Lawyer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 3/2/2006 Other Health Professional Australia
Primary
Concomitant
Renal Failure Hospitalization 1/1/1996 Female 3/13/2006 Physician United States
Primary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 3/13/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2003 61 Female 170 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Breast Cancer Other Serious 12/16/2005 Female 135 lb 3/28/2006 Physician United States
Primary
Concomitant
Pulmonary Vascular Disorder Hospitalization 9/21/2005 73 Male 3/28/2006 Physician Japan
Primary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 3/1/2005 68 Female 3/31/2006 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 2/24/2006 55 Female 260 lb 3/28/2006 Other Health Professional Australia
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 160 lb 4/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/9/2006 70 Male 170 lb 4/10/2006 Physician Canada
Primary
Concomitant
International Normalised Ratio Increased Other Serious 9/6/2005 75 Female 168 lb 4/11/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Non-hodgkin's Lymphoma Other Serious 60 Female 4/17/2006 Consumer United States
Primary
Concomitant
Vomiting 1/1/2005 46 Female 154 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Vitamin B12 Increased Other Serious 2/8/2006 Female 172 lb 4/24/2006 Physician Australia
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Renal Disorder Hospitalization 1/1/1999 49 Female 386 lb 5/5/2006 Lawyer United States
Primary
Concomitant
Medical Observation Hospitalization 12/13/2005 Female 187 lb 5/5/2006 Other Health Professional United Kingdom
Primary
Concomitant
Tremor Hospitalization 1/1/2000 58 Female 181 lb 5/10/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Ulcer Other Serious 10/30/1999 72 Female 141 lb 5/16/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 5/18/2006 Physician Australia
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Rales Other Serious 73 Male 6/1/2006 Consumer United Kingdom
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 3/1/2005 68 Female 6/6/2006 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 88 Female 174 lb 6/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Vertigo Hospitalization 88 Female 174 lb 6/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Telangiectasia Hospitalization 9/19/2005 73 Female 111 lb 6/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Exertional Hospitalization 4/8/2006 Male 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Skin Laceration Hospitalization 6/3/2006 Female 101 lb 7/27/2006 Pharmacist United States
Primary
Concomitant
Bone Marrow Disorder Hospitalization 7/5/2006 79 Male 8/11/2006 Other Health Professional France
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Retching Hospitalization 5/14/2006 74 Male 243 lb 6/19/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hallucination Hospitalization 7/2/2006 68 Male 139 lb 7/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Acute Leukaemia Hospitalization 7/5/2006 79 Male 9/15/2006 Other Health Professional France
Primary
Concomitant
Rhabdomyolysis Hospitalization 4/1/2006 Male 9/21/2006 Physician Singapore
Primary
Concomitant
Metabolic Acidosis Hospitalization 64 Female 9/29/2006
Primary
Secondary
Concomitant
Arterial Thrombosis Limb Other Serious 62 Male 9/29/2006
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 10/1/2006 80 Male 92 lb 12/12/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/1/2006 71 Male 2/16/2007 Physician Singapore
Primary
Concomitant
Hypotension Hospitalization 12/2/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2004 72 Female 150 lb 3/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2004 72 Female 150 lb 3/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 11/1/2006 84 Male 3/19/2007 Physician United States
Primary
Concomitant
Lung Disorder 6/1/2006 19 Male 93 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Rash Hospitalization 10/20/2005 71 Male 4/23/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 10/1/2006 87 Female 117 lb 4/12/2007 Other Health Professional Germany
Primary
Concomitant
Resuscitation Life Threatening 3/30/2007 75 Male 4/26/2007 Pharmacist Singapore
Primary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ulcer Hospitalization 3/1/2007 61 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 5/14/2007
Primary
Secondary
Concomitant
Muscular Weakness Other Serious 69 Female 2/6/2007 Pharmacist Canada
Primary
Concomitant
Dyspnoea Other Serious 11/1/2006 84 Male 123 lb 5/29/2007 Consumer United States
Primary
Concomitant
Fall Other Serious 11/1/2006 84 Male 123 lb 6/11/2007 Consumer United States
Primary
Concomitant
Subdural Haemorrhage Life Threatening 5/23/2007 90 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Sedation Life Threatening 5/22/2007 54 Male 6/7/2007 Pharmacist United States
Primary
Concomitant
Thromboembolic Stroke Hospitalization 11/25/2004 70 Male 6/15/2007 Physician United Kingdom
Primary
Concomitant
Dyspnoea Other Serious 11/1/2006 84 Male 123 lb 6/22/2007 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 64 Female 8/8/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 12/1/2004 79 Female 8/13/2007 Other Health Professional France
Primary
Secondary
Concomitant
Drug Interaction Other Serious 68 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 82 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 80 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 67 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Other Serious 73 Male 8/16/2007 Sweden
Primary
Concomitant
Interacting
Drug Interaction Death 70 Female 8/16/2007 Sweden
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 1/7/2007 74 Female 8/13/2007 Other Health Professional Ireland
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 8/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 8/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 64 Female 8/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2005 Female 8/22/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 4/17/2007 83 Male 8/22/2007 Physician Sweden
Primary
Secondary
Concomitant
Sudden Death Death 7/16/2007 62 Female 117 lb 7/26/2007 Mexico
Primary
Secondary
Concomitant
Renal Failure Other Serious 64 Female 8/28/2007 United Kingdom
Primary
Secondary
Concomitant
Application Site Pruritus 1/26/2007 82 Female 8/27/2007 Consumer United States
Primary
Concomitant
Dyspnoea Other Serious 11/1/2006 84 Male 123 lb 9/24/2007 Physician United States
Primary
Concomitant
Rheumatoid Arthritis Disability 4/1/2007 9/28/2007 Consumer United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Other Serious 8/14/2007 58 Male 280 lb 9/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious Female 9/28/2007 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 36 Female 12/27/2007 Other Health Professional Japan
Primary
Concomitant
Visual Disturbance Hospitalization 3/1/2007 63 Male 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 3/1/2007 63 Male 1/9/2008 Physician United States
Primary
Secondary
Concomitant
Palpitations Other Serious 3/1/2007 83 Female 139 lb 1/8/2008 Consumer Germany
Primary
Concomitant
Pulmonary Hypertension Hospitalization 36 Female 1/22/2008 Other Health Professional Japan
Primary
Concomitant
Cerebrovascular Accident Life Threatening 12/8/2007 82 Male 128 lb 1/24/2008 Consumer Brazil
Primary
Concomitant
Visual Disturbance Other Serious 6/9/2004 63 Male 1/28/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Other Serious 12/11/2007 94 Female 99 lb 2/4/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 2/14/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/2005 76 Male 2/19/2008 Consumer Australia
Primary
Concomitant
Death Death 2/20/2008 Male 132 lb 4/18/2008 Physician Japan
Primary
Concomitant
Prothrombin Time Shortened Other Serious 5/1/2003 Female 125 lb 4/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 4/18/2008 United Kingdom
Primary
Concomitant
Deafness Neurosensory Disability 4/7/2008 78 Male 5/13/2008 Other Health Professional United Kingdom
Primary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 143 lb 5/29/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 83 Female 5/29/2008 United Kingdom
Primary
Secondary
Concomitant
Vision Blurred Death 4/10/2008 67 Male 158 lb 5/28/2008 Consumer United States
Primary
Concomitant
Dysphagia Other Serious 5/24/2008 Female 108 lb 6/13/2008 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Other Serious 11/21/2005 80 Male 121 lb 8/7/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nausea Hospitalization 8/5/2007 77 Female 10/13/2008 Other Health Professional Australia
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Brain Stem Infarction Death 7/4/2008 Male 139 lb 12/29/2008 Physician Japan
Primary
Concomitant
Drug Interaction Hospitalization 9/29/2008 64 Female 12/30/2008 Other Health Professional France
Primary
Concomitant
Interacting
Sudden Death Death 12/7/2008 72 Male 1/6/2009 Physician United Kingdom
Primary
Concomitant
Overdose Death 4/1/2008 50 Male 231 lb 1/12/2009 Other Health Professional Canada
Primary
Secondary
Concomitant
Emphysema 11/1/2008 Male 1/12/2009 Consumer
Primary
Concomitant

Drug Data