Digoxin combined with Warfarin Sodium

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Refusal Of Treatment By Patient Hospitalization Female 1/4/2006 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 71 Male 1/2/2006
Primary
Concomitant
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 58 Male 1/6/2006 United Kingdom
Primary
Concomitant
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Retinitis Pigmentosa Other Serious 1/1/2005 51 Female 143 lb 1/11/2006 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2005 74 Female 1/5/2006 Canada
Primary
Concomitant
Nausea Other Serious 40 Male 218 lb 1/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Constipation Other Serious 1/1/1991 67 Male 170 lb 1/13/2006 United States
Primary
Secondary
Concomitant
Retinitis Pigmentosa Other Serious 1/1/2005 51 Female 143 lb 1/13/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 78 Female 1/12/2006 United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Death Other Serious 12/25/2004 74 Male 1/20/2006 Pharmacist United States
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 78 Female 1/24/2006 United Kingdom
Primary
Secondary
Concomitant
Somnolence Required Intervention 12/18/2005 78 Male 166 lb 12/21/2005 Pharmacist United States
Primary
Concomitant
Retroperitoneal Haematoma Required Intervention 12/1/2005 81 Male 190 lb 1/18/2006 Physician United States
Primary
Secondary
Concomitant
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Thermal Burn 10/2/2005 Male 12/7/2005 United States
Primary
Concomitant
Weight Decreased 84 Female 115 lb 12/7/2005 Consumer United States
Primary
Concomitant
Renal Impairment Required Intervention 3/1/2005 49 Female 2/1/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/16/2005 85 Male 137 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Insomnia 9/4/2005 80 Male 140 lb 1/5/2006 Consumer United States
Primary
Concomitant
Fall Other Serious 1/12/2006 85 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Lethargy Hospitalization 1/25/2006 80 Male 180 lb 2/2/2006 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 80 Male 172 lb 2/8/2006 United States
Primary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Retinitis Pigmentosa Other Serious 1/1/2005 51 Female 143 lb 2/8/2006 Physician United States
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 106 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 58 Male 2/14/2006 Consumer United Kingdom
Primary
Concomitant
Haematoma Life Threatening 6/26/2005 82 Female 1/10/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/1/2005 78 Male 156 lb 1/20/2006 United States
Primary
Concomitant
Psychotic Disorder Hospitalization 6/1/2005 59 Male 262 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pelvic Fracture Hospitalization 1/1/2001 77 Female 116 lb 2/21/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 2/22/2006 Physician United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 6/1/2005 Male 263 lb 3/1/2006 Physician United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 5/20/2002 56 Female 2/23/2006 Physician Japan
Primary
Concomitant
Ventricular Hypertrophy Other Serious 79 Male 180 lb 2/22/2006 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/10/2006 Female 175 lb 2/22/2006 United States
Primary
Concomitant
Thrombosis Hospitalization 3/3/2005 70 Female 2/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Fissures 73 Female 110 lb 12/7/2005 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 1/5/2006 84 Male 2/26/2006 Other Health Professional France
Primary
Secondary
Concomitant
Nausea Hospitalization 9/18/2005 59 Female 2/24/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 80 Male 172 lb 3/2/2006 Physician United States
Primary
Concomitant
Skin Maceration Hospitalization 12/31/2005 89 Female 168 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Visual Disturbance Other Serious 12/1/2005 74 Female 2/15/2006 Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 12/20/2003 79 Male 225 lb 3/9/2006 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/1/2006 Physician Japan
Primary
Concomitant
Vitreous Floaters Other Serious 10/15/2005 80 Male 245 lb 1/20/2006 United States
Primary
Concomitant
Psychotic Disorder Hospitalization 1/19/2006 59 Male 262 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/8/2006 Physician Japan
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/16/2006 Physician Canada
Primary
Concomitant
Pain In Extremity Hospitalization 1/1/2002 74 Male 145 lb 12/29/2005 United States
Primary
Concomitant
Renal Failure Other Serious 1/13/2005 83 Male 134 lb 3/17/2006 Physician Canada
Primary
Concomitant
Overdose Hospitalization 1/23/2006 28 Female 3/2/2006 France
Primary
Secondary
Concomitant
Paralysis Hospitalization 2/22/2006 Female 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Atrial Fibrillation Death 9/28/2005 70 Male 123 lb 3/23/2006 Physician
Primary
Concomitant
Loss Of Consciousness Other Serious 12/1/2005 74 Female 3/7/2006 Canada
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/8/2006 52 Female 3/21/2006 Physician Japan
Primary
Concomitant
Dysphagia Disability 70 Female 3/20/2006 Pharmacist Japan
Primary
Concomitant
Resuscitation Hospitalization 64 Female 3/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Haemolysis Other Serious 89 Male 3/23/2006 Pharmacist Japan
Primary
Concomitant
Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 2/9/2006 52 Female 128 lb 3/24/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 68 Female 3/23/2006 Physician Japan
Primary
Secondary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 4/4/2006 Physician United States
Primary
Concomitant
Sudden Death Death 2/16/2006 77 Female 114 lb 3/16/2006 Consumer United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
White Blood Cell Count Increased Death 9/9/2004 73 Male 3/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Therapy Non-responder Life Threatening 58 Male 4/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Neoplasm Malignant 6/1/2004 69 Male 3/31/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/1/2005 68 Female 4/5/2006 Physician Japan
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 11/27/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/1/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/7/2005 73 Male 4/13/2006 Physician Sweden
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 161 lb 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/31/2005 58 Male 186 lb 4/11/2006 United States
Primary
Concomitant
Tremor Disability 11/30/2005 75 Female 176 lb 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/6/2006 Female 4/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Epistaxis Hospitalization 2/2/2006 54 Female 179 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea 2/16/2006 50 Female 280 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Haemorrhage Intracranial Hospitalization 4/1/2006 Male 125 lb 4/3/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 56 Female 4/18/2006 Physician Pakistan
Primary
Secondary
Concomitant
Shock Life Threatening 6/22/2005 78 Female 4/26/2006 Japan
Primary
Secondary
Concomitant
Subdural Haematoma Death 1/28/2006 63 Male 1/31/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Death 1/1/1999 79 Female 4/19/2006 Canada
Primary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 4/26/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Dyspnoea 1/26/2006 70 Female 2/21/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 64 Female 5/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 74 Male 5/8/2006 Australia
Primary
Concomitant
Metabolic Acidosis Hospitalization 64 Female 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 64 Female 5/9/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 73 Male 5/5/2006 Physician United Kingdom
Primary
Secondary
Death Death 4/22/2006 88 Male 5/8/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2006 86 Female 160 lb 5/8/2006 Consumer United States
Primary
Secondary
Concomitant
Sedation Other Serious 4/3/2006 70 Female 143 lb 5/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Visual Acuity Reduced Hospitalization 8/30/2005 89 Female 121 lb 5/16/2006 Other Health Professional Australia
Primary
Concomitant
Sick Sinus Syndrome Required Intervention 4/12/2006 88 Female 169 lb 5/10/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 64 Female 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 89 Male 142 lb 5/10/2006 United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 161 lb 5/8/2006 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 3/10/2006 89 Male Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Thrombosis Other Serious 3/3/2005 70 Female 5/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/3/2006 86 Male 194 lb 5/20/2006 Pharmacist United States
Primary
Concomitant
Melaena Hospitalization 1/25/2006 84 Male 174 lb 5/20/2006 Pharmacist United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Required Intervention 12/29/2004 50 Female 2/23/2005 Pharmacist United States
Primary
Secondary
Cardiac Failure Other Serious 73 Male 5/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Initial Insomnia 2/17/2006 81 Male 215 lb 4/3/2006 Consumer United States
Primary
Concomitant
Insomnia 8/1/2005 86 Male 192 lb 4/3/2006 Consumer United States
Primary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Blood Parathyroid Hormone Increased 8/22/2005 Male 3/13/2006 United States
Primary
Secondary
Concomitant
Hypocalcaemia Hospitalization 12/18/2005 71 Male 3/13/2006 Physician United States
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 99 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Insomnia 11/1/2005 53 Male 155 lb 4/3/2006 Consumer United States
Primary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Carotid Artery Occlusion Other Serious 5/14/2006 Male 156 lb 6/5/2006 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 5/7/2005 Male 163 lb 6/6/2006 Physician
Primary
Concomitant
Stomach Discomfort Hospitalization 1/1/2005 87 Male 134 lb 5/31/2006 United States
Primary
Concomitant
Tremor Hospitalization 88 Female 175 lb 6/7/2006 United States
Primary
Secondary
Concomitant
Paralysis Other Serious 2/22/2006 79 Female 6/9/2006 Other Health Professional Japan
Primary
Interacting
Pharyngolaryngeal Pain 2/1/2006 39 Female 179 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 6/2/2006 Physician Australia
Primary
Concomitant
Muscular Weakness Other Serious 12/1/2005 60 Female 320 lb 4/20/2006 Consumer United States
Primary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2006 77 Male 5/5/2006 Consumer United States
Primary
Concomitant
Sinusitis 28 Female 120 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Unresponsive To Verbal Stimuli Life Threatening 4/28/2006 Female 105 lb 6/20/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 64 Female 6/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 1/1/2006 Female 172 lb 6/21/2006 Physician Australia
Primary
Secondary
Concomitant
Muscle Spasms 3/29/2006 69 Male 6/21/2006 Consumer United States
Primary
Concomitant
Hypoglycaemia Other Serious 56 Male 6/21/2006 Consumer United States
Primary
Concomitant
Blood Glucose Increased Other Serious 6/11/2006 81 Female 6/14/2006 Consumer United States
Primary
Concomitant

Drug Data