Digoxin combined with Verapamil

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Hepatic Function Abnormal Other Serious 10/1/2005 71 Male 1/3/2006 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 1/3/2006 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 58 Male 1/6/2006 United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 12/1/2005 74 Female 1/5/2006 Canada
Primary
Concomitant
Osteoporosis Other Serious 1/1/2004 Female 112 lb 1/23/2006 Consumer United States
Primary
Concomitant
Coronary Artery Occlusion Other Serious 11/1/2005 74 Female 233 lb 2/1/2006 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/1/2006 Japan
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/8/2006 Physician Japan
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 2/9/2006 Physician United Kingdom
Primary
Concomitant
Poisoning Hospitalization 10/25/2005 88 Female 2/21/2006
Primary
Secondary
Concomitant
Vomiting Hospitalization 58 Male 2/14/2006 Consumer United Kingdom
Primary
Concomitant
Cardio-respiratory Arrest Death 11/28/2005 78 Female 2/23/2006 Consumer United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 2/22/2006 Physician United Kingdom
Primary
Concomitant
Coronary Artery Occlusion Other Serious 11/1/2005 74 Female 233 lb 2/22/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 2/27/2006 Physician Japan
Primary
Concomitant
Skin Fissures 73 Female 110 lb 12/7/2005 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Diabetes Mellitus Inadequate Control Hospitalization 2/11/2003 59 Male 220 lb 3/7/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 5/30/2005 65 Male 137 lb 3/2/2006 Physician Japan
Primary
Concomitant
Ventricular Fibrillation Life Threatening 12/14/2005 73 Female 3/2/2006 Germany
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 12/1/2005 74 Female 2/15/2006 Canada
Primary
Concomitant
Vomiting Hospitalization 2/8/2006 71 Female 140 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/1996 Female 3/13/2006 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 12/1/2005 74 Female 3/7/2006 Canada
Primary
Concomitant
Resuscitation Hospitalization 64 Female 3/22/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2004 Female 91 lb 3/29/2006 Consumer United States
Primary
Concomitant
Thrombosis Other Serious 5/31/2004 Male 165 lb 3/31/2006 Lawyer United States
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Nasal Dryness Other Serious 3/24/2006 74 Female 4/3/2006 Consumer United States
Primary
Concomitant
Respiratory Tract Infection Other Serious 12/8/2005 71 Male 156 lb 3/28/2006 Physician United Kingdom
Primary
Concomitant
Prostate Examination Abnormal Other Serious 68 Male 3/28/2006 United States
Primary
Concomitant
Troponin Increased Hospitalization 10/5/2003 73 Female 4/7/2006 Physician Australia
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
Therapy Non-responder Life Threatening 58 Male 4/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rectal Haemorrhage Hospitalization 11/27/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Rectal Haemorrhage Other Serious 12/1/2005 74 Female 3/24/2006 Canada
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 2/8/2006 71 Female 140 lb 4/6/2006 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 4/6/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Tremor Disability 11/30/2005 75 Female 176 lb 4/12/2006 Other Health Professional United Kingdom
Primary
Concomitant
Coronary Artery Disease Hospitalization 2/1/2006 Male 4/26/2006 Physician United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 64 Female 5/2/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Metabolic Acidosis Hospitalization 64 Female 5/8/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Hypotension Hospitalization 5/3/2006 79 Female 168 lb 5/4/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/13/2006 80 Female 154 lb 2/14/2006 Pharmacist United States
Primary
Concomitant
Ulcer Other Serious 10/30/1999 72 Female 141 lb 5/16/2006 Physician United States
Primary
Concomitant
Respiratory Rate Increased Other Serious 64 Female 5/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Oliguria Hospitalization 64 Female 5/17/2006 Consumer United Kingdom
Primary
Secondary
Dyspnoea Hospitalization 64 Female 5/23/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Death 2/7/2006 85 Male 5/16/2006 Pharmacist United States
Primary
Concomitant
Leukaemia Other Serious 1/1/2006 80 Male 172 lb 5/16/2006 Physician United States
Primary
Concomitant
Tremor 3/17/2006 67 Male 5/30/2006 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 64 Female 6/1/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2006 71 Female 140 lb 6/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 64 Female 6/13/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 6/11/2006 81 Female 6/14/2006 Consumer United States
Primary
Concomitant
Heart Rate Decreased Other Serious 5/23/2006 72 Female 6/22/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 1/1/2006 64 Female 6/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sciatica 2/26/2006 Female 5/8/2006 Consumer United States
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 4/8/2006 80 Male 172 lb 6/13/2006 Physician United States
Primary
Concomitant
Vision Blurred 3/1/2006 Female 5/19/2006 United States
Primary
Secondary
Concomitant
Glycosylated Haemoglobin Increased Other Serious 6/11/2006 81 Female 6/30/2006 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/9/2005 80 Female 7/18/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Thrombocytopenia Hospitalization 10/9/2005 80 Female 7/19/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2005 Female 7/31/2006 Consumer United States
Primary
Secondary
Concomitant
Spinal Compression Fracture 78 Female 5/24/2006 Consumer United States
Primary
Concomitant
Skin Fissures 73 Female 110 lb 5/24/2006 Consumer United States
Primary
Concomitant
Deep Vein Thrombosis Hospitalization 5/4/2006 Male 8/8/2006 Physician United States
Primary
Concomitant
Therapeutic Response Decreased Hospitalization 1/1/2006 75 Male 8/3/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Renal Impairment Life Threatening 64 Female 8/12/2006 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 4/1/2006 76 Male 195 lb 8/21/2006 United States
Primary
Concomitant
Vision Blurred Hospitalization 1/1/2005 Female 8/31/2006 Consumer United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Death 1/1/2006 79 Male 8/24/2006 Physician United States
Primary
Concomitant
Drug Interaction 1/1/2005 69 Female 165 lb 9/14/2006 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 9/12/2006 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Dysphagia Other Serious 71 Female 9/20/2006 Other Health Professional Germany
Primary
Concomitant
Foreign Body Trauma Hospitalization 71 Female 128 lb 9/22/2006 Physician Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 71 Female 128 lb 9/21/2006 Physician Germany
Primary
Concomitant
Metabolic Acidosis Hospitalization 64 Female 9/29/2006
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 10/4/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 78 Male 10/6/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Therapy Non-responder Other Serious 64 Female 10/18/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Hospitalization 5/4/2006 Male 11/22/2006 Physician United States
Primary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 64 Female 1/12/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Memory Impairment 7/9/2006 88 Female 11/7/2006 Consumer United States
Primary
Concomitant
Dry Skin Male 11/6/2006 United States
Primary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 1/24/2007 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Death Death 1/1/2005 66 2/9/2007 Physician United States
Primary
Secondary
Occult Blood Positive Hospitalization 9/29/2006 75 Male 216 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 1/20/2007 60 Male 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Fluctuation Death 2/10/2007 63 Male 140 lb 3/5/2007 Physician United States
Primary
Concomitant
Motor Dysfunction Other Serious 2/24/2007 Female 115 lb 3/14/2007 Consumer United States
Primary
Concomitant
Interacting
Urticaria Other Serious 64 Male 256 lb 7/23/2004 Physician United States
Primary
Concomitant
Cataract Required Intervention 9/1/2001 83 Female 181 lb 6/6/2003 Physician United States
Primary
Concomitant
Oedema Peripheral Other Serious Male 126 lb 2/5/2004 United States
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Life Threatening 2/5/2007 82 Male 165 lb 3/2/2007 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 71 Female 128 lb 3/14/2007 Physician Germany
Primary
Concomitant
Renal Failure Other Serious 64 Female 3/27/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Death Death 1/1/2004 73 3/22/2007 Pharmacist United States
Primary
Secondary
Renal Impairment Other Serious 64 Female 3/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 12/14/2006 Male 198 lb 4/17/2007 Physician United States
Primary
Concomitant
Ill-defined Disorder Male 4/30/2007 Consumer United States
Primary
Concomitant
Somnolence Hospitalization 3/19/2007 68 Female 99 lb 5/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 12/5/2006 79 Male 5/23/2007 Physician United States
Primary
Concomitant
Wheezing Other Serious 6/1/1999 70 Female 5/25/2007 Physician Australia
Primary
Secondary
Concomitant
Tongue Discolouration 83 Male 2/5/2007 Physician United States
Primary
Concomitant
Pneumonia Male 2/22/2007 United States
Primary
Concomitant
Spinal Cord Ischaemia Hospitalization 1/10/2007 77 Female 157 lb 4/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 12/14/2006 75 Male 216 lb 5/29/2007 Pharmacist United States
Primary
Concomitant
Insomnia 12/1/2006 86 Female 175 lb 4/12/2007 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Death 5/13/2007 70 Female 101 lb 5/30/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/13/2006 72 Female 6/15/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 72 Female 6/20/2007 Consumer United Kingdom
Primary
Secondary
Vomiting Death 72 Female 6/20/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 72 Female 6/19/2007 United Kingdom
Primary
Secondary
Vomiting Hospitalization 72 Female 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 72 Female 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Yawning Hospitalization 6/14/2007 42 Male 104 lb 6/26/2007 Japan
Primary
Concomitant
Mallory-weiss Syndrome Hospitalization 2/4/2007 79 Male 146 lb 6/6/2007 Pharmacist United States
Primary
Concomitant
Yawning Hospitalization 6/14/2007 42 Male 104 lb 7/6/2007 Japan
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/1997 Female 7/20/2007 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/13/2006 72 Female 7/9/2007 United Kingdom
Primary
Secondary
Subdural Haematoma Life Threatening 8/1/2007 81 Male 8/9/2007 Pharmacist United States
Primary
Concomitant
Confusional State Hospitalization 4/28/2007 Male 8/16/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 8/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 8/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Life Threatening 64 Female 8/20/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Life Threatening 64 Female 8/6/2007 United Kingdom
Primary
Secondary
Concomitant
Photosensitivity Reaction Other Serious 50 Female 8/29/2007 Other Health Professional Australia
Primary
Secondary
Concomitant
Throat Tightness Other Serious 6/5/2007 84 Female 8/31/2007 Physician United States
Primary
Concomitant
Photosensitivity Reaction Other Serious 50 Female 8/30/2007 Australia
Primary
Secondary
Concomitant
Renal Impairment Other Serious 64 Female 9/5/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 7/1/2007 69 Female 143 lb 9/12/2007 Consumer United Kingdom
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 9/13/2007 Physician United States
Primary
Concomitant
Pancreatitis Acute Required Intervention 6/1/2007 80 Female 176 lb 9/14/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2007 67 Male 174 lb 8/29/2007 Australia
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/24/2007 67 Male 174 lb 9/6/2007 Australia
Primary
Secondary
Concomitant
Muscular Weakness Hospitalization 7/27/2007 82 Male 9/21/2007 Pharmacist United States
Primary
Secondary
Renal Failure Life Threatening 64 Female 9/4/2007 United Kingdom
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/10/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Multiple Drug Overdose Death 4/23/2003 39 Male 10/9/2007 Other Health Professional Japan
Primary
Secondary
Disease Progression Death 1/1/2006 79 Male 10/2/2007 Physician United States
Primary
Concomitant
Yawning Hospitalization 6/14/2007 42 Male 104 lb 10/3/2007 Japan
Primary
Concomitant
Rash Other Serious 8/26/2007 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 10/17/2007 Other Health Professional United States
Primary
Concomitant
Interacting
Multiple Drug Overdose Death 4/23/2003 39 Male 157 lb 10/17/2007 Other Health Professional Japan
Primary
Secondary
Pharmaceutical Product Complaint Other Serious 4/14/2007 58 Male 10/25/2007 Consumer United States
Primary
Concomitant
Blood Glucose Increased 10/1/2007 69 Male 192 lb 11/8/2007 Consumer United States
Primary
Concomitant
Anaemia Other Serious 8/17/2007 79 Male 12/10/2007 Consumer Italy
Primary
Concomitant

Drug Data