Digoxin combined with Torsemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
Hepatitis Hospitalization 12/28/2005 78 Male 2/2/2006 Physician Spain
Primary
Secondary
Hypoglycaemic Coma Hospitalization 9/24/2005 80 Female 2/1/2006 Switzerland
Primary
Secondary
Concomitant
Sepsis Life Threatening 12/27/2005 69 Male 200 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/28/2005 78 Female 2/20/2006 Physician Spain
Primary
Secondary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Oral Intake Reduced Hospitalization 2/1/2006 79 Female 2/27/2006 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Psychomotor Skills Impaired Other Serious 2/1/2006 78 Female 3/1/2006 Consumer France
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/24/2005 57 Male 3/3/2006 Other Health Professional United States
Primary
Concomitant
Hypoglycaemia Hospitalization 2/1/2006 78 Female 2/28/2006 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 10/2/2005 84 Male 2/2/2006 Pharmacist United States
Primary
Concomitant
Hypoglycaemic Coma Hospitalization 3/1/2006 62 Male 176 lb 3/13/2006 Physician Japan
Primary
Concomitant
Hypoglycaemic Coma Hospitalization 3/1/2006 62 Male 176 lb 3/15/2006 Physician Japan
Primary
Concomitant
Anaemia Hospitalization 2/28/2005 80 Female 178 lb 12/27/2005 Other Health Professional United States
Primary
Secondary
Concomitant
Hypoglycaemic Coma Hospitalization 3/1/2006 62 Male 176 lb 3/23/2006 Physician Japan
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Haemolysis Other Serious 89 Male 3/23/2006 Pharmacist Japan
Primary
Concomitant
Throat Irritation 11/4/2005 38 Female 137 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Hospitalization 3/1/2006 62 Male 176 lb 4/14/2006 Physician Japan
Primary
Concomitant
Ventricular Dysfunction Other Serious 81 Male 4/6/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 3/1/2006 62 Male 176 lb 4/25/2006 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 4/14/2006 14 Female 5/4/2006 Physician Japan
Primary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatitis Hospitalization 57 Female 6/1/2006 United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 4/11/2006 60 Female 126 lb 6/13/2006 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Somnolence 1/11/2006 Female 169 lb 8/9/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 8/18/2006 Pharmacist United States
Primary
Concomitant
Throat Irritation 11/4/2005 38 Female 137 lb 7/25/2006 Pharmacist United States
Primary
Concomitant
Aspartate Aminotransferase Increased Other Serious 4/13/2006 14 Female 97 lb 9/6/2006 Physician Japan
Primary
Concomitant
Dysphagia Other Serious 71 Female 9/20/2006 Other Health Professional Germany
Primary
Concomitant
Foreign Body Trauma Hospitalization 71 Female 128 lb 9/22/2006 Physician Germany
Primary
Concomitant
Tachyarrhythmia Other Serious 6/1/2005 Female 9/22/2006 Physician Germany
Primary
Concomitant
Wrong Technique In Drug Usage Process Hospitalization 71 Female 128 lb 9/21/2006 Physician Germany
Primary
Concomitant
Hypoalbuminaemia Required Intervention 1/17/2006 40 Female 106 lb 9/20/2006 Physician Japan
Primary
Concomitant
Pancreatitis Other Serious 3/28/2006 60 Male 243 lb 8/22/2006 Physician United States
Primary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Retroperitoneal Haemorrhage Death 6/2/2006 60 Male 194 lb 11/20/2006 Pharmacist United States
Primary
Concomitant
Skin Exfoliation 5/1/2006 Male 12/22/2006 Consumer United States
Primary
Concomitant
Pulmonary Hypertension 43 Female 161 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Wheezing Hospitalization 1/1/2003 67 Female 2/7/2007 Consumer United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/28/2005 80 Female 179 lb 10/23/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 71 Female 128 lb 3/14/2007 Physician Germany
Primary
Concomitant
Wheezing Hospitalization 1/1/2003 67 Female 4/10/2007 Consumer United States
Primary
Concomitant
Syncope Required Intervention 76 Male 4/4/2007 Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 1/31/2007 84 Female 4/12/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Orthostatic Hypotension Hospitalization 5/17/2004 78 Female 4/5/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Oedema Peripheral Hospitalization 1/1/2006 76 Male 195 lb 12/13/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 4/19/2007 71 Male 6/20/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Interacting
Yawning Hospitalization 6/14/2007 42 Male 104 lb 6/26/2007 Japan
Primary
Concomitant
Subarachnoid Haemorrhage Hospitalization 4/16/2007 73 Male 134 lb 5/18/2007 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 1/31/2007 85 Female 7/11/2007 Other Health Professional Switzerland
Primary
Concomitant
Interacting
Yawning Hospitalization 6/14/2007 42 Male 104 lb 7/6/2007 Japan
Primary
Concomitant
Musculoskeletal Pain 1/1/2006 Male 206 lb 7/26/2007 Consumer United States
Primary
Concomitant
Oedema Hospitalization 9/10/2007 Female 194 lb 10/3/2007 Pharmacist United States
Primary
Concomitant
Oedema Hospitalization 9/10/2007 Female 194 lb 10/12/2007 Pharmacist United States
Primary
Concomitant
Yawning Hospitalization 6/14/2007 42 Male 104 lb 10/3/2007 Japan
Primary
Concomitant
Sinus Rhythm Hospitalization Female 10/20/2007 Other Health Professional Switzerland
Primary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2007 67 Male 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Fatigue Other Serious Female 10/29/2007 Other Health Professional Switzerland
Primary
Concomitant
Liver Injury Required Intervention 11/13/2007 46 Female 110 lb 11/27/2007 Physician Germany
Primary
Concomitant
Jaundice Cholestatic Required Intervention 11/13/2007 46 Female 110 lb 12/14/2007 Other Health Professional Germany
Primary
Concomitant
Vomiting Hospitalization 11/1/2007 85 Female 134 lb 12/20/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Bradyarrhythmia Hospitalization 12/5/2007 61 Female 154 lb 1/28/2008 Physician Lithuania
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 11/16/2007 70 Male 238 lb 1/29/2008 Physician United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 12/20/2007 Female 2/4/2008 Physician Japan
Primary
Concomitant
Pyrexia Other Serious 12/20/2007 Female 2/14/2008 Physician Japan
Primary
Concomitant
Weight Increased Other Serious Male 276 lb 2/15/2008 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 58 Female 2/20/2008 Physician Spain
Primary
Concomitant
Ventricular Fibrillation Other Serious 58 Female 3/7/2008 Physician Spain
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Pancreatitis Acute Life Threatening 12/1/2006 79 Female 3/19/2008 Pharmacist Spain
Primary
Secondary
Pancreatitis Acute Life Threatening 12/1/2006 79 Female 3/25/2008 Consumer Spain
Primary
Secondary
Rash Disability 12/27/2007 Male 296 lb 3/25/2008 Consumer United States
Primary
Concomitant
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Pancreatitis Acute Life Threatening 12/1/2006 79 Female 4/2/2008 Pharmacist Spain
Primary
Secondary
Pancreatitis Acute Life Threatening 12/1/2006 79 Female 4/4/2008 Consumer Spain
Primary
Secondary
Cardiac Failure Congestive Hospitalization 2/20/2008 43 Male 100 lb 4/2/2008 Physician Japan
Primary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Protein Total Decreased Hospitalization 12/12/2007 83 Female 88 lb 4/11/2008 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Life Threatening 3/11/2008 60 Female 190 lb 4/14/2008 Physician Switzerland
Primary
Secondary
Concomitant
Suicide Attempt Life Threatening 3/28/2008 43 Male 100 lb 4/9/2008 Physician Japan
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/15/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Vomiting Life Threatening 2/22/2008 80 Female 4/18/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Vomiting Hospitalization 58 Female 4/15/2008 Physician Spain
Primary
Secondary
Renal Failure Life Threatening 3/28/2008 43 Male 100 lb 4/14/2008 Physician Japan
Primary
Secondary
Concomitant
Death Death 5/10/1998 Female 155 lb 4/22/2008 Physician United States
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/23/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Renal Failure Life Threatening 3/28/2008 43 Male 100 lb 4/21/2008 Physician Japan
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 2/20/2008 43 Male 100 lb 4/18/2008 Physician Japan
Primary
Concomitant
Bradycardia Hospitalization 8/1/2007 80 Female 4/16/2008 Spain
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Pyrexia Life Threatening 3/11/2008 59 Female 190 lb 5/23/2008 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 4/15/2008 75 Female 165 lb 5/16/2008 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 4/1/2008 79 Male 180 lb 5/28/2008 United States
Primary
Concomitant
Cardiac Failure Hospitalization 10/10/2007 Male 175 lb 6/4/2008 United States
Primary
Concomitant
Protein Total Decreased Hospitalization 12/12/2007 83 Female 88 lb 6/9/2008 Physician Japan
Primary
Secondary
Concomitant
Pain Hospitalization 5/8/2008 49 Female 220 lb 6/16/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2008 71 Male 172 lb 7/1/2008 United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 7/10/2008 Consumer United States
Primary
Concomitant
Diarrhoea Hospitalization 7/2/2008 85 Male 7/28/2008 Consumer Switzerland
Primary
Concomitant
Syncope Hospitalization 6/16/2008 Male 7/28/2008 Physician Germany
Primary
Concomitant
Pneumonia Hospitalization 4/29/2008 75 Female 165 lb 7/16/2008 Other Health Professional United States
Primary
Concomitant
Neck Pain Other Serious 7/1/2008 Female 7/23/2008 Consumer United States
Primary
Concomitant
Tremor 1/1/2007 72 Female 7/7/2008 Consumer United States
Primary
Concomitant
Neck Pain Other Serious 7/1/2008 Female 8/2/2008 Physician United States
Primary
Concomitant
Therapeutic Response Unexpected Other Serious 11/1/2007 64 Female 8/15/2008 Consumer United States
Primary
Concomitant
Weight Fluctuation 6/8/2007 43 Female 142 lb 8/14/2008 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Death 3/31/2008 77 Female 8/20/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death 3/31/2008 77 Female 8/22/2008 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 4/21/2008 66 Male 155 lb 8/27/2008 United States
Primary
Concomitant
Right Ventricular Failure Hospitalization 1/21/2008 Male 9/9/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Required Intervention 4/21/2008 66 Male 155 lb 9/10/2008 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2008 Male 185 lb 9/26/2008 United States
Primary
Concomitant
Nausea Hospitalization 3/27/2008 79 Female 164 lb 9/22/2008 United States
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/22/2008 Male 9/29/2008 Physician Japan
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/22/2008 Male 10/2/2008 Physician Japan
Primary
Concomitant
Drug Prescribing Error Hospitalization 7/25/2008 79 Female 183 lb 10/21/2008 Other Health Professional France
Primary
Concomitant
Interacting
Pruritus 10/13/2008 Male 11/26/2008 United States
Primary
Concomitant
Anal Haemorrhage Hospitalization 83 Female 11/27/2008 Consumer Spain
Primary
Concomitant
Blood Creatinine Increased Other Serious 7/22/2008 Male 12/1/2008 Physician Japan
Primary
Concomitant
Orthostatic Hypotension 54 Male 205 lb 12/17/2008 United States
Primary
Concomitant
Postnasal Drip Hospitalization 10/1/2008 60 Female 137 lb 12/16/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 12/23/2008 Physician Spain
Primary
Concomitant
Renal Disorder Other Serious 7/22/2008 1/9/2009 Other Health Professional Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 43 Female 143 lb 1/14/2009
Primary
Secondary
Death Death 1/9/2009 Female 179 lb 1/20/2009 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 43 Female 1/21/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2008 81 Female 1/28/2009 Physician Spain
Primary
Concomitant
Death Death 1/9/2009 Female 179 lb 1/29/2009 Physician United States
Primary
Concomitant
Syncope Life Threatening 11/18/2008 81 Female 2/2/2009 Spain
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 1/1/2007 2/13/2009 Physician Poland
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/1/2008 74 Male 3/6/2009 Physician Switzerland
Primary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 6/8/2008 43 Female 142 lb 3/5/2009 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 43 Female 3/5/2009 United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 7/1/2008 Male 3/9/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Cardiac Failure Life Threatening 1/26/2009 80 Female 77 lb 3/16/2009 Other Health Professional Korea, Republic Of
Primary
Concomitant
Stress Other Serious 43 Female 144 lb 3/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 3/12/2009 Male 3/19/2009 Consumer United States
Primary
Concomitant
Death Hospitalization 3/12/2009 Male 3/31/2009 Physician United States
Primary
Concomitant
Death Hospitalization 3/12/2009 Male 3/31/2009 Physician United States
Primary
Concomitant
Renal Disorder Hospitalization 1/1/2008 Male 195 lb 4/2/2009 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 4/10/2009 Female 4/21/2009 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 6/1/2007 98 Female 4/21/2009 Physician Switzerland
Primary
Secondary
Concomitant
Pneumonia Hospitalization 89 Female 5/8/2009 Physician Spain
Primary
Concomitant
Weight Decreased Other Serious 83 Male 5/5/2009
Primary
Concomitant
Vision Blurred Other Serious 10/1/2007 87 Male 5/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Liver Injury Other Serious 83 Male 5/7/2009 United States
Primary
Concomitant

Drug Data