Digoxin combined with Tiotropium Bromide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Aortic Dissection Death 4/5/2005 Male 2/1/2006 Consumer United Kingdom
Primary
Secondary
Haemoglobin Decreased Life Threatening 4/4/2006 73 Female 5/4/2006
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 4/4/2006 73 Female 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/11/2006 Other Health Professional Netherlands
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/29/2006 Other Health Professional Netherlands
Primary
Concomitant
Sepsis Death 9/3/2006 45 Male 99 lb 10/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Death 9/3/2006 83 Male 99 lb 10/12/2006 United Kingdom
Primary
Concomitant
Retinal Artery Occlusion Disability 10/23/2006 75 Male 174 lb 12/14/2006 Other Health Professional United Kingdom
Primary
Concomitant
Dyspnoea Hospitalization 1/5/2006 47 Male 164 lb 1/23/2007 Consumer United States
Primary
Concomitant
Insomnia 11/1/2006 85 Male 162 lb 1/12/2007 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/3/2006 83 Male 99 lb 5/18/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocythaemia Other Serious 10/30/2006 88 Female 110 lb 6/11/2007 Other Health Professional Portugal
Primary
Concomitant
Soft Tissue Infection Other Serious 1/17/2007 Male 271 lb 7/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Nausea Other Serious 1/15/2007 68 Male 8/30/2007 Physician Spain
Primary
Secondary
Concomitant
Confusional State Hospitalization 10/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neck Pain Other Serious 12/26/2007 75 Male 201 lb 1/25/2008 Other Health Professional United Kingdom
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/11/2008 Other Health Professional Netherlands
Primary
Concomitant
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 3/27/2008 Other Health Professional Netherlands
Primary
Concomitant
Prothrombin Level Decreased Hospitalization 2/14/2008 67 Female 4/9/2008 Other Health Professional Sweden
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/7/2008 Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/13/2008 Sweden
Primary
Concomitant
Confusional State Hospitalization 9/1/2007 75 Male 5/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Retinal Artery Occlusion Disability 10/23/2006 75 Male 174 lb 6/10/2008 Other Health Professional United Kingdom
Primary
Concomitant
Intra-abdominal Haematoma Hospitalization 4/28/2008 77 Male 231 lb 6/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Venous Insufficiency Hospitalization 5/1/2008 88 Male 7/9/2008 Physician France
Primary
Secondary
Concomitant
Hip Fracture Other Serious 6/24/2008 Male 8/6/2008 Canada
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/24/2008 Male 8/15/2008 Canada
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 8/18/2008 Other Health Professional Netherlands
Primary
Concomitant
Skin Discolouration Hospitalization 8/22/2008 65 Female 145 lb 9/15/2008 Consumer United States
Primary
Concomitant
Prostatic Specific Antigen Increased Other Serious 6/24/2008 Male 9/15/2008 Canada
Primary
Concomitant
Allergic Granulomatous Angiitis Hospitalization 8/13/2006 75 Female 9/19/2008 Other Health Professional Netherlands
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/3/2008 United States
Primary
Concomitant
Tremor Hospitalization 7/1/2008 Female 130 lb 10/6/2008 United States
Primary
Concomitant
Respiratory Failure Other Serious 77 Male 101 lb 10/19/2008 Other Health Professional Japan
Primary
Concomitant
Tendon Rupture Hospitalization 68 Male 10/13/2008 United Kingdom
Primary
Concomitant
Respiratory Failure Other Serious 77 Male 101 lb 11/17/2008 Other Health Professional Japan
Primary
Concomitant
Muscle Spasms 9/23/2008 Female 130 lb 11/26/2008
Primary
Concomitant
Renal Impairment Other Serious 10/14/2005 Female 12/8/2008 Canada
Primary
Concomitant
Hiccups Hospitalization 10/25/2008 80 Male 12/19/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Hiccups Hospitalization 10/25/2008 80 Male 12/31/2008 Other Health Professional Sweden
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/31/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/30/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/2/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/3/2009
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 3/10/2009 4/10/2009 Physician United States
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/10/2009 Pharmacist Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/15/2009 Pharmacist Japan
Primary
Secondary
Pneumonia Death 66 Male 4/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/22/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Palatal Oedema Hospitalization 1/24/2009 77 Male 152 lb 5/20/2009 Other Health Professional France
Primary
Secondary
Palatal Oedema Hospitalization 1/24/2009 77 Male 152 lb 6/2/2009 Other Health Professional France
Primary
Secondary
Syncope Other Serious 4/15/2009 7/8/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 66 Male 7/1/2009 Physician Korea, Republic Of
Primary
Concomitant
Venous Insufficiency Hospitalization 5/1/2008 88 Male 7/13/2009 Physician France
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 7/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 7/1/2009 82 Male 7/30/2009 Consumer United Kingdom
Primary
Concomitant
Syncope Other Serious 4/15/2009 8/10/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Other Serious 4/15/2009 8/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Surgery Hospitalization 64 Male 8/20/2009 United States
Primary
Concomitant
Death Death 9/2/2009 60 Male 9/10/2009 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 7/12/2009 59 Male 9/14/2009 Other Health Professional United States
Primary
Concomitant
Cardiac Arrest Death 9/2/2009 60 Male 214 lb 10/2/2009 Other Health Professional United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 10/18/2009 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 64 Male 201 lb 10/26/2009 United States
Primary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Other Serious 73 Female 2/16/2010
Primary
Secondary
Concomitant
Use Of Accessory Respiratory Muscles Life Threatening 2/7/2010 77 Male 3/2/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hyperkalaemia Hospitalization 10/9/2009 89 Female 3/12/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/9/2009 89 Female 3/15/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 64 Male 201 lb 3/25/2010 United States
Primary
Concomitant
Lower Respiratory Tract Infection Life Threatening 4/8/2010 69 Male 4/30/2010 Physician Australia
Primary
Concomitant
Hyperkalaemia Hospitalization 10/9/2009 89 Female 5/11/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Hyperkalaemia Hospitalization 10/9/2009 89 Female 5/25/2010 Other Health Professional Italy
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 6/17/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/26/2010 65 Male 6/17/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 6/18/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 65 Male 8/27/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 4/26/2010 65 Male 8/30/2010 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Renal Failure Hospitalization 73 Female 10/15/2010 Other Health Professional Germany
Primary
Concomitant
Renal Failure Hospitalization 73 Female 10/22/2010 Other Health Professional Germany
Primary
Concomitant
Varicose Vein Other Serious 1/1/2009 11/4/2010 Physician Germany
Primary
Secondary
Concomitant
Vomiting Other Serious 73 Female 10/28/2010 Other Health Professional Spain
Primary
Concomitant
Renal Failure Hospitalization 73 Female 11/10/2010 Other Health Professional Spain
Primary
Concomitant
Renal Failure Hospitalization 73 Female 11/10/2010 Other Health Professional Spain
Primary
Concomitant
Renal Failure Hospitalization 73 Female 11/12/2010 Other Health Professional Germany
Primary
Concomitant
Renal Failure Other Serious 78 Male 11/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 73 Female 12/6/2010 Other Health Professional Spain
Primary
Concomitant
Thrombocytopenia Life Threatening 73 Female 12/13/2010 Spain
Primary
Secondary
Right Ventricular Failure Other Serious 1/1/2009 71 Female 207 lb 2/8/2011 Consumer Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Other Serious 1/1/2009 71 Female 207 lb 3/21/2011 Consumer Germany
Primary
Secondary
Concomitant
Hepatotoxicity Hospitalization 61 Male 236 lb 3/30/2011 Other Health Professional Poland
Primary
Concomitant
Oedema Peripheral Other Serious 7/1/2010 67 Female 168 lb 4/4/2011 Consumer United States
Primary
Secondary
Concomitant
Colour Blindness Disability 11/1/2010 70 Male 168 lb 4/14/2011 Other Health Professional United Kingdom
Primary
Concomitant
Mobility Decreased Other Serious 7/1/2010 67 Female 168 lb 4/15/2011 Consumer United States
Primary
Secondary
Concomitant
Colour Blindness Disability 11/1/2010 70 Male 168 lb 4/20/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Bearing Difficulty Other Serious 4/25/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Weight Bearing Difficulty Other Serious 4/25/2011 75 Female 6/1/2011 Other Health Professional United Kingdom
Primary
Concomitant
Bacterial Test Positive Death 11/1/2010 80 Male 5/20/2011 Physician United States
Primary
Concomitant
Head Injury Death 4/27/2009 75 Male 6/20/2011 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Aplasia Pure Red Cell Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cystitis Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Neutralising Antibodies Positive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Gastritis Erosive Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Cardioactive Drug Level Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Gastritis Erosive Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Varicose Vein Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Fatigue Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Vaginal Abscess Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Colonic Polyp Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Anal Fissure Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Haemorrhoids Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Pain Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Hospitalization 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Refractory Anaemia Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Pain Other Serious 1/1/2009 71 Female 207 lb 6/21/2011 Physician Germany
Primary
Secondary
Concomitant

Drug Data