Digoxin combined with Spironolactone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Gynaecomastia Other Serious 1/1/2001 65 Male 226 lb 1/3/2006 Physician United States
Primary
Secondary
Concomitant
Haemarthrosis Hospitalization 11/1/2005 59 Female 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Interacting
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Disease Progression Hospitalization 3/11/2005 65 Male 1/17/2006 Physician Russian Federation
Primary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Hyperthermia Other Serious 1/1/2001 65 Male 226 lb 1/13/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 1/1/2001 69 Female 126 lb 1/19/2006 Lawyer United States
Primary
Concomitant
Pancreatitis Acute Other Serious 1/7/2006 74 Male 1/18/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 78 Female 1/19/2006 Physician Greece
Primary
Secondary
Renal Failure Other Serious 9/1/2005 78 Male 1/19/2006 Physician Netherlands
Primary
Secondary
Concomitant
Pulmonary Haemorrhage Hospitalization 2/24/2002 24 Female 1/27/2006 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 1/23/2006 Physician Netherlands
Primary
Secondary
Concomitant
Malaise Other Serious 8/20/2005 17 Female 108 lb 1/21/2006 Physician Japan
Primary
Concomitant
Hyperaldosteronism Hospitalization 12/28/2004 73 Female 121 lb 2/3/2006 Consumer France
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 3/1/2005 49 Female 2/1/2006 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 7/26/2005 69 Male 1/30/2006 Physician China
Primary
Concomitant
Fall Other Serious 1/12/2006 85 Female 2/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Malaise Other Serious 12/18/2005 57 Female 2/9/2006 Consumer United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 11/1/2005 62 Male 2/3/2006 Sweden
Primary
Concomitant
Vomiting Other Serious 70 Male 2/7/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 106 lb 2/8/2006 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 9/5/2005 52 Female 101 lb 2/9/2006 Physician Japan
Primary
Concomitant
Hypokalaemia Hospitalization 6/17/2005 Female 160 lb 10/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
White Blood Cell Count Decreased Death 9/5/2005 33 Male 2/13/2006 Physician Japan
Primary
Concomitant
Weight Increased Life Threatening 3/1/2005 71 Female 2/21/2006 Other Health Professional Germany
Primary
Concomitant
Pyrexia Hospitalization 11/1/2005 1 Male 2/14/2006 Physician Japan
Primary
Concomitant
Weight Decreased Life Threatening 11/28/2003 80 Male 2/10/2006 Physician Peru
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/1/2006 96 Female 132 lb 2/23/2006 Other Health Professional Brazil
Primary
Concomitant
Therapy Non-responder Hospitalization 12/20/2005 74 Male 187 lb 2/16/2006 Czech Republic
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 11/29/2005 52 Male 190 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/1/2005 Male 2/22/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 1/1/1990 72 Male 2/10/2006 United States
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Hepatitis Toxic Other Serious 10/18/2005 77 Male 3/2/2006 Physician Spain
Primary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Subdural Haematoma Other Serious 1/27/2004 66 Female 2/27/2006 France
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 8/1/2005 67 Female 2/23/2006 Consumer United States
Primary
Concomitant
Hypokinesia Death 74 Male 173 lb 3/7/2006 Physician Canada
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Required Intervention 10/2/2005 84 Male 2/2/2006 Pharmacist United States
Primary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 3/13/2006 Physician United States
Primary
Concomitant
Thrombosis Life Threatening 2/7/2006 55 Male 3/8/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombosis Life Threatening 2/7/2006 55 Male 3/9/2006 United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/16/2006
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/10/2006 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Somnolence Hospitalization 11/17/2005 59 Female 99 lb 3/14/2006 Physician Japan
Primary
Secondary
Concomitant
Vertigo Hospitalization 1/1/2005 63 Male 3/16/2006 Physician Switzerland
Primary
Concomitant
Myocardial Infarction Hospitalization 12/1/2003 61 Female 170 lb 3/23/2006 Lawyer United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/26/2001 54 Female 146 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Urine Colour Abnormal Hospitalization 1/28/2005 45 Male 3/27/2006 Physician Philippines
Primary
Concomitant
Septic Shock Life Threatening 12/22/2005 75 Female 154 lb 3/31/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea Hospitalization 3/1/2006 92 Female 170 lb 4/4/2006 Physician United States
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
White Blood Cell Count Increased Death 9/9/2004 73 Male 3/31/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 12/4/2003 63 Female 154 lb 4/10/2006 Lawyer United States
Primary
Concomitant
Rash Erythematous Other Serious 10/1/2001 76 Male 4/12/2006 Other Health Professional France
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 4/7/2006 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 12/4/2002 75 Male 4/19/2006 Physician United States
Primary
Concomitant
Vertebral Artery Stenosis Hospitalization 12/4/2002 75 Male 4/20/2006 Physician United States
Primary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Epistaxis Hospitalization 2/2/2006 54 Female 179 lb 4/7/2006 Pharmacist United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 9/4/2005 Male 2/21/2006 Physician United States
Primary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 4/26/2006 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 4/27/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 11/16/2005 29 Male 4/19/2006 Physician Australia
Primary
Concomitant
Palpitations Other Serious 2/26/2006 17 Female 87 lb 4/24/2006 Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 73 Male 5/5/2006 Physician United Kingdom
Primary
Secondary
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Congestion Other Serious 2/26/2006 17 Female 87 lb 5/10/2006 Japan
Primary
Concomitant
Renal Impairment Hospitalization 1/1/2005 78 Male 5/12/2006 Physician Netherlands
Primary
Secondary
Concomitant
Spinal Laminectomy Hospitalization 1/1/2000 65 Female 251 lb 5/18/2006 Physician United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/19/2006 83 Female 112 lb 5/23/2006 Consumer United States
Primary
Concomitant
Mouth Haemorrhage Hospitalization 3/5/2006 84 Male 210 lb 5/16/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased 5/11/2005 90 Male 205 lb 5/30/2006 Consumer United States
Primary
Concomitant
Tremor 3/17/2006 67 Male 5/30/2006 Consumer United States
Primary
Concomitant
Eosinophilia Other Serious 3/9/2006 93 Female 5/24/2006 France
Primary
Secondary
Concomitant
Cardiac Failure Other Serious 73 Male 5/31/2006 Other Health Professional United Kingdom
Primary
Secondary
Rales Other Serious 73 Male 6/1/2006 Consumer United Kingdom
Primary
Secondary
Liver Function Test Abnormal Hospitalization 9/5/2005 52 Female 101 lb 5/25/2006 Physician Japan
Primary
Concomitant
Malaise Hospitalization 11/17/2005 59 Female 99 lb 5/25/2006 Physician Japan
Primary
Secondary
Concomitant
Urticaria Generalised Hospitalization 2/20/2005 54 Female 130 lb 5/25/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 1/1/1990 72 Male 5/24/2006 Consumer United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 6/2/2006 Physician Australia
Primary
Concomitant
Rash Maculo-papular Other Serious 6/7/2006 66 Female 150 lb 6/12/2006 Pharmacist United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 10/31/2004 89 Female 6/8/2006 Other Health Professional Sweden
Primary
Secondary
Concomitant
Sinusitis 28 Female 120 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Oedema Peripheral Other Serious 73 Male 6/12/2006 Other Health Professional United Kingdom
Primary
Secondary
Cardiac Failure Other Serious 1/1/2000 73 Male 6/12/2006 United Kingdom
Primary
Secondary
Skin Nodule Hospitalization 10/1/2003 Female 119 lb 6/22/2006 Germany
Primary
Concomitant
Weight Decreased Other Serious 2/1/2006 83 Female 112 lb 6/21/2006 United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/22/2005 57 Female 143 lb 6/23/2006 Belgium
Primary
Concomitant
Presbyacusis Disability 10/15/2005 84 Male 6/23/2006 Other Health Professional Sweden
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/1/2006 76 Female 132 lb 7/6/2006 Pharmacist United States
Primary
Concomitant
Leukaemia Hospitalization 6/4/2006 61 Male 198 lb 7/5/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Other Serious 6/28/2006 68 Male 7/17/2006 Physician Spain
Primary
Concomitant
Coma Other Serious 5/1/2005 75 Male 7/19/2006 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Skin Lesion Hospitalization 3/2/2006 41 Male 214 lb 5/22/2006 Pharmacist United States
Primary
Concomitant
Pericarditis Constrictive Hospitalization 10/1/2003 Female 119 lb 7/20/2006 Germany
Primary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 7/5/2006 Pharmacist United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 3/11/2005 65 Male 7/24/2006 Physician Russian Federation
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 7/27/2004 55 Female 7/19/2006 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 34 Male 7/21/2006 Other Health Professional Spain
Primary
Concomitant
Sexual Dysfunction Other Serious 5/4/2006 78 Male 115 lb 7/24/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 7/31/2006 United Kingdom
Primary
Secondary
Vomiting Hospitalization 74 Male 7/21/2006 Other Health Professional Denmark
Primary
Concomitant
Tearfulness Required Intervention 77 Female 7/26/2006 Physician United States
Primary
Concomitant
Pulmonary Hypertension Other Serious 2/26/2006 17 Female 87 lb 7/25/2006 Japan
Primary
Concomitant
Cardiac Failure Other Serious 3/13/2006 69 Male 190 lb 7/26/2006 Physician Argentina
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/4/2006 Physician Spain
Primary
Concomitant
Vomiting Hospitalization 74 Male 7/31/2006 Other Health Professional Denmark
Primary
Secondary
Concomitant
Staphylococcal Infection Life Threatening 7/27/2004 55 Female 7/31/2006 United States
Primary
Concomitant
Renal Impairment Hospitalization 7/4/2006 69 Female 7/28/2006 Physician Brazil
Primary
Concomitant
Weight Decreased 6/1/2005 Male 215 lb 8/8/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/1/2006 91 Female 8/3/2006 United Kingdom
Primary
Secondary
Wheezing Hospitalization 1/1/1994 Male 8/14/2006 Consumer United States
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 6/15/2000 67 Male 8/15/2006 France
Primary
Concomitant
Thrombosis Other Serious 2/7/2006 55 Male 8/8/2006 Denmark
Primary
Concomitant
Renal Failure Acute Other Serious 4/4/2006 91 Male 8/8/2006 Denmark
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/1/2002 57 Male 8/8/2006 Other Health Professional Japan
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/3/2006 91 Female 8/4/2006 United Kingdom
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/1/2006 Female 8/16/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization 11/7/2005 33 Female 8/15/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/24/2006 Physician Spain
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/5/2006 91 Female 8/21/2006 Denmark
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/1/2006 Female 8/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Therapy Non-responder Life Threatening 7/1/2006 69 Female 8/14/2006 Brazil
Primary
Concomitant
Wheezing Hospitalization 1/1/2004 Male 8/29/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/1/2006 Female 8/18/2006 United States
Primary
Secondary
Concomitant
Wheezing Hospitalization 1/1/2004 Male 8/30/2006 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/1/2006 Female 8/25/2006 Physician United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 6/28/2006 58 Female 8/18/2006 Pharmacist United States
Primary
Concomitant

Drug Data