Digoxin combined with Sodium Bicarbonate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Hepatic Failure Death 81 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Yellow Skin Other Serious 12/28/2002 63 Male 1/30/2006 Physician Philippines
Primary
Concomitant
Sepsis Hospitalization 5/11/2005 60 Male 3/24/2006 United Kingdom
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased 3/1/1999 Female 127 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Memory Impairment 7/9/2006 88 Female 11/7/2006 Consumer United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 8/24/2006 69 Male 165 lb 7/26/2007 Physician France
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Hair Growth Abnormal 1/1/2003 71 Female 10/25/2007 Consumer United States
Primary
Concomitant
Visual Disturbance 1/1/2002 57 Male 11/14/2007 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 2/8/2008 Sweden
Primary
Concomitant
Vomiting Hospitalization 1/1/2008 76 Male 159 lb 2/21/2008 United States
Primary
Concomitant
Troponin Increased Hospitalization 2/20/2008 62 Female 3/6/2008 Sweden
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Troponin Increased Hospitalization 2/20/2008 62 Female 3/19/2008 Sweden
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 3/28/2008 Sweden
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/7/2008 Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/13/2008 Sweden
Primary
Concomitant
Rectal Haemorrhage Hospitalization 3/6/2008 80 Female 5/28/2008 Pharmacist United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Multi-organ Failure Hospitalization 5/2/2008 Male 6/9/2008 Physician Switzerland
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Anaemia Other Serious Male 7/2/2008 Consumer United States
Primary
Concomitant
Therapeutic Response Decreased 3/1/1999 Female 127 lb 7/25/2008 Other Health Professional United States
Primary
Concomitant
Anaemia Other Serious Male 7/31/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 76 Male 159 lb 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Troponin Increased Hospitalization 2/20/2008 62 Female 9/23/2008 Sweden
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 86 Female 10/8/2008
Primary
Secondary
Concomitant
Cardiac Arrest Death 1/2/2009 Male 157 lb 1/13/2009 Physician Thailand
Primary
Concomitant
Convulsion Hospitalization 2/1/2009 69 Male 2/17/2009 Other Health Professional United States
Primary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Sepsis Hospitalization 12/29/2008 Female 5/1/2009 Physician Canada
Primary
Concomitant
Visual Impairment Hospitalization Male 6/14/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 89 Male 6/22/2009 Lawyer United States
Primary
Concomitant
Wound Other Serious 1/1/2004 8/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Sepsis Other Serious 12/29/2008 Female 8/6/2009 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Death 68 Male 8/4/2009 Lawyer United States
Primary
Concomitant
Visual Impairment Hospitalization 78 Male 8/5/2009 United States
Primary
Concomitant
Visceral Arterial Ischaemia Death 5/23/2009 Female 8/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Visual Impairment Hospitalization 78 Male 172 lb 8/11/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/26/2008 85 Female 12/1/2009 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 12/11/2009 United States
Primary
Concomitant
Wound Infection Fungal Death 10/21/2009 Male 110 lb 12/18/2009 Physician Hong Kong
Primary
Concomitant
Thrombocytopenia Hospitalization 67 Female 1/13/2010 United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 2/4/2010 Lawyer United States
Primary
Concomitant
Superinfection Death 9/30/2009 82 Female 2/1/2010 Denmark
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Traumatic Haematoma Death 9/30/2009 82 Female 2/25/2010 Denmark
Primary
Concomitant
Pancreatic Carcinoma Other Serious 5/2/2008 Male 3/5/2010 Physician Switzerland
Primary
Concomitant
Vomiting Hospitalization 69 Male 3/5/2010 Lawyer United States
Primary
Concomitant
Vision Blurred Hospitalization 89 Male 3/16/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 10/20/2009 69 Male 174 lb 4/26/2010 Physician Chile
Primary
Secondary
Concomitant
Ventricular Hypokinesia Hospitalization 60 Female 155 lb 4/20/2010 Lawyer United States
Primary
Concomitant
Intestinal Obstruction Hospitalization 11/9/2008 71 Male 126 lb 5/4/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 81 Female 5/7/2010 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 78 Female 117 lb 4/26/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/21/2010 89 Female 6/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 5/21/2010 89 Female 6/23/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Restrictive Cardiomyopathy Hospitalization 10/20/2009 69 Male 174 lb 7/9/2010 Physician Chile
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 2/6/2008 69 Male 148 lb 7/15/2010 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 74 Female 7/16/2010 United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 2/1/2008 69 Male 148 lb 9/1/2010 Lawyer United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 5/17/2010 55 Male 147 lb 9/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/1/2008 12 Female 66 lb 10/28/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 69 Male 148 lb 11/24/2010 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Septic Shock Death 12/7/2010 83 Male 124 lb 12/16/2010 Other Health Professional Taiwan, Province Of China
Primary
Secondary
Concomitant
Vomiting Other Serious 2/1/2008 69 Male 148 lb 12/29/2010 Lawyer United States
Primary
Secondary
Concomitant
Stress Urinary Incontinence Hospitalization 4/26/2008 85 Female 100 lb 1/13/2011 Lawyer United States
Primary
Concomitant
Injury Death 9/30/2006 65 Female 126 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Electrocardiogram Abnormal Hospitalization 60 Male 2/24/2011 United States
Primary
Concomitant
Hyperuricaemia Death 11/10/2010 79 Female 97 lb 3/9/2011 Physician Japan
Primary
Concomitant
Anxiety Death 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 9/18/2006 66 Male 178 lb 3/21/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Aortic Valve Stenosis Death 60 Female 155 lb 3/15/2011 Lawyer United States
Primary
Concomitant
Tachyarrhythmia Hospitalization 77 Male 3/17/2011 Lawyer United States
Primary
Concomitant
Multi-organ Failure Other Serious 12/26/2000 59 Male 110 lb 4/5/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 12/26/2000 59 Male 110 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Death 11/10/2010 79 Female 97 lb 4/5/2011 Physician Japan
Primary
Concomitant
Blood Pressure Inadequately Controlled Hospitalization Female 3/24/2011 United States
Primary
Concomitant
Pain Other Serious 1/1/2007 65 Male 183 lb 4/6/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 1/28/2004 61 Female 126 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 82 Male 3/30/2011 United States
Primary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Death 12/26/2004 54 Male 205 lb 4/18/2011 Consumer United States
Primary
Concomitant
Erythema Other Serious 3/1/2011 70 Male 230 lb 4/26/2011 Consumer United States
Primary
Concomitant
Fear Death 12/26/2004 54 Male 205 lb 4/29/2011 Consumer United States
Primary
Concomitant
Anhedonia Other Serious 6/17/2003 79 Female 198 lb 5/12/2011 Consumer United States
Primary
Concomitant
Anxiety Death 8/1/1996 17 Male 97 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 6/17/2003 79 Female 198 lb 5/21/2011 Lawyer United States
Primary
Concomitant
Death Death 1/12/2001 16 Male 115 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Death 2/26/2003 48 Female 123 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 6/30/2006 68 Female 139 lb 5/28/2011 Other Health Professional United States
Primary
Concomitant
Stress Other Serious 3 Male 79 lb 6/1/2011 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 61 Male 172 lb 6/2/2011 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 4/26/2003 67 Male 201 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 11/20/2004 23 Female 135 lb 6/4/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Hospitalization 12/18/2006 64 Male 130 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 37 Female 6/22/2011 Lawyer United States
Primary
Concomitant
Shock Hospitalization 71 Female 6/20/2011 United States
Primary
Concomitant
Stress Death 4/23/1995 45 Male 200 lb 7/11/2011 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/1/2004 63 Female 7/27/2011 Physician United States
Primary
Concomitant
Anxiety Death 11/1/2005 51 Female 139 lb 7/27/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 1/1/2003 48 Male 258 lb 7/28/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 12/26/2004 54 Male 205 lb 8/2/2011 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 7/20/2011 72 Female 8/2/2011 Consumer United States
Primary
Concomitant
Rash Other Serious 6/28/2011 82 Female 105 lb 8/29/2011 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/8/2011 69 Male 144 lb 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Neutropenia Other Serious 11/24/2010 63 Male 9/15/2011 Physician Japan
Primary
Secondary
Concomitant
Myocardial Fibrosis Disability 1/1/2000 11 Male 77 lb 9/27/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Hospitalization 9/8/2011 69 Male 144 lb 10/3/2011 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Death 12/26/2000 59 Male 110 lb 10/14/2011 Consumer United States
Primary
Concomitant
Anaemia Other Serious 11/1/2007 58 Male 137 lb 10/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Anxiety Other Serious 1/28/2004 61 Female 126 lb 10/20/2011 Other Health Professional United States
Primary
Concomitant
Post Procedural Haemorrhage Hospitalization 7/20/2011 72 Female 112 lb 10/27/2011 Physician United States
Primary
Concomitant
Arthralgia Death 11/1/2005 51 Female 139 lb 11/12/2011 Consumer United States
Primary
Secondary
Concomitant
Injury Other Serious 12/26/2000 59 Male 110 lb 11/21/2011 Lawyer United States
Primary
Concomitant
Klebsiella Test Positive Death 10/21/2009 78 Male 110 lb 11/28/2011 Physician Hong Kong
Primary
Concomitant
Renal Impairment Life Threatening Female 12/12/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bradycardia Life Threatening 4/11/2008 75 Female 11/23/2011 Lawyer United States
Primary
Concomitant
Blood Potassium Increased Death Female 130 lb 11/29/2011 Lawyer United States
Primary
Concomitant
Aortic Arteriosclerosis Other Serious 1/28/2008 86 Female 12/8/2011 Lawyer United States
Primary
Concomitant
Hepatic Steatosis Hospitalization Female 110 lb 12/15/2011 Lawyer United States
Primary
Concomitant
Infarction Death 1/11/2012 70 Male 1/26/2012 Consumer United States
Primary
Concomitant
Gastric Haemorrhage Other Serious 1/1/2011 60 Female 134 lb 2/28/2012 Consumer United States
Primary
Concomitant
Arrhythmia Other Serious 11/24/2010 63 Male 3/27/2012 Physician Japan
Primary
Secondary
Concomitant
Malaise Other Serious 2/1/2012 76 Male 204 lb 3/27/2012 Physician United States
Primary
Secondary
Concomitant

Drug Data