Digoxin combined with Sintrom

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Melaena Hospitalization 10/1/2005 75 Male 1/2/2006
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 11/29/2005 92 Female 1/3/2006
Primary
Secondary
Concomitant
Renal Haematoma Hospitalization 11/29/2005 92 Female 1/10/2006 Physician France
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
Renal Haematoma Hospitalization 11/29/2005 92 Female 1/13/2006 Physician France
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 1/29/2006 78 Female 3/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Face Oedema Other Serious 1/16/2004 70 Female 4/5/2006 Consumer France
Primary
Secondary
Concomitant
Pneumonia Death 2/1/2006 78 Male 130 lb 4/6/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pneumonia Death 2/1/2006 78 Male 130 lb 4/5/2006 Spain
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/18/2006 67 Male 265 lb 4/13/2006 Consumer France
Primary
Secondary
Concomitant
Hepatitis Cholestatic Hospitalization 1/30/2006 76 Female 4/17/2006 Spain
Primary
Secondary
Concomitant
Polyuria Hospitalization 2/18/2006 67 Male 265 lb 4/25/2006 Consumer France
Primary
Secondary
Concomitant
Polyuria Hospitalization 2/18/2006 67 Male 265 lb 5/15/2006 Consumer France
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/30/2006 76 Female 5/30/2006 Spain
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 4/16/2006 76 Female 123 lb 6/15/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/14/2004 42 Female 187 lb 6/21/2006 Physician Spain
Primary
Concomitant
Hypertension Other Serious 12/16/2005 73 Male 198 lb 6/22/2006 Physician Spain
Primary
Concomitant
Visual Acuity Reduced Hospitalization 6/8/2006 76 Female 7/10/2006 Other Health Professional France
Primary
Secondary
Concomitant
Haemolytic Anaemia Hospitalization 4/16/2006 76 Female 123 lb 7/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Shortened Death 5/7/2006 66 Male 154 lb 8/14/2006 Physician Spain
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 6/20/2006 89 Female 9/1/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Life Threatening 5/5/2002 Male 265 lb 10/3/2006 Physician Spain
Primary
Secondary
Concomitant
Vascular Calcification Life Threatening 5/5/2002 Male 265 lb 10/16/2006 Physician Spain
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 6/15/2006 67 Female 10/17/2006 France
Primary
Secondary
Pleural Effusion Hospitalization 9/1/2006 64 Male 11/21/2006 France
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 11/11/2006 73 Male 11/22/2006 Greece
Primary
Concomitant
Skin Lesion Hospitalization 6/15/2006 67 Female 12/6/2006 France
Primary
Secondary
Hepatitis Cholestatic Hospitalization 11/15/2006 80 Male 12/12/2006 Physician France
Primary
Secondary
Concomitant
Dermatitis Bullous Other Serious 6/15/2006 67 Female 12/11/2006 Other Health Professional France
Primary
Secondary
Prothrombin Level Decreased Life Threatening 5/8/2006 83 Male 12/19/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2005 71 Male 12/28/2006 France
Primary
Concomitant
Respiratory Disorder Life Threatening 8/21/2006 91 Female 12/26/2006 France
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 9/14/2006 81 Female 1/12/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 8/21/2006 78 Male 1/15/2007 Spain
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 9/14/2006 81 Female 1/24/2007 Other Health Professional France
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 9/29/2006 86 Female 95 lb 2/2/2007 Other Health Professional Switzerland
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Hospitalization 12/4/2006 46 Male 1/31/2007 France
Primary
Secondary
Hypertension Life Threatening 1/8/2007 Female 2/12/2007 Physician Bulgaria
Primary
Concomitant
Vaginal Haemorrhage Hospitalization 10/31/2006 86 Female 2/16/2007 Other Health Professional France
Primary
Concomitant
Interacting
Drug Interaction Hospitalization 10/12/2006 80 Female 2/16/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Thrombocytopenic Purpura Hospitalization 1/5/2007 83 Male 3/13/2007 Consumer Germany
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Hospitalization 1/19/2007 82 Female 3/14/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 3/16/2007 Physician Bulgaria
Primary
Concomitant
Hepatitis Cholestatic Hospitalization 11/15/2006 80 Male 4/2/2007 Physician France
Primary
Secondary
Concomitant
Hyperkalaemia Life Threatening 1/11/2007 67 Male 4/4/2007 Pharmacist Spain
Primary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 4/6/2007 Physician Bulgaria
Primary
Concomitant
Renal Failure Acute Hospitalization 1/21/2007 84 Female 148 lb 4/30/2007
Primary
Secondary
Concomitant
Cerebral Ischaemia Life Threatening 4/25/2007 76 Male 165 lb 5/7/2007 Physician Bulgaria
Primary
Concomitant
Cerebral Thrombosis Life Threatening 4/25/2007 76 Male 165 lb 5/11/2007 Physician Bulgaria
Primary
Concomitant
Haemorrhage Intracranial Life Threatening 1/31/2007 65 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Renal Failure Acute Other Serious 11/5/2006 89 Female 112 lb 5/12/2007 Physician Switzerland
Primary
Secondary
Concomitant
Renal Failure Other Serious 11/1/2006 89 Male 112 lb 5/21/2007 Physician Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 1/31/2007 65 Female 5/16/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Haemorrhage Intracranial Life Threatening 1/31/2007 65 Female 5/22/2007 Consumer Spain
Primary
Secondary
Renal Failure Other Serious 11/1/2006 Male 112 lb 5/22/2007 Physician Switzerland
Primary
Secondary
Concomitant
Rash Macular Other Serious 69 Female 5/24/2007 Physician Algeria
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 1/31/2007 65 Female 5/23/2007 Other Health Professional Spain
Primary
Secondary
Concomitant
Sideroblastic Anaemia Other Serious 10/1/2006 5/31/2007 Physician France
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 4/25/2007 76 Male 165 lb 6/18/2007 Physician Bulgaria
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 4/25/2007 76 Male 165 lb 6/19/2007 Physician Bulgaria
Primary
Concomitant
Renal Failure Acute Hospitalization 11/19/2006 71 Male 6/22/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Sideroblastic Anaemia Other Serious 10/23/2006 7/5/2007 Physician France
Primary
Concomitant
Renal Failure Acute Hospitalization 11/19/2006 71 Male 7/6/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Hypertension Other Serious 5/29/2007 7/9/2007 Physician Poland
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 7/16/2007 Physician Bulgaria
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/17/2007 75 Female 8/14/2007 Spain
Primary
Secondary
Concomitant
Cerebral Haemorrhage Death 8/24/2007 86 Female 9/6/2007 Consumer Spain
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/8/2007 85 Male 10/17/2007 Other Health Professional France
Primary
Concomitant
Interacting
Loss Of Consciousness Hospitalization 2/24/2007 85 Female 10/18/2007 Consumer Spain
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2007 85 Male 10/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Thrombocytopenia Death 7/7/2007 77 Male 10/25/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Hospitalization 3/22/2007 73 Female 11/9/2007 Spain
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death 3/22/2007 73 Female 11/12/2007 Consumer Spain
Primary
Secondary
Concomitant
Traumatic Haematoma Other Serious 5/10/2007 79 Female 11/20/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
International Normalised Ratio Increased Other Serious 5/15/2007 79 Female 11/26/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 10/24/2007 74 Female 11/30/2007 Consumer Spain
Primary
Concomitant
Interacting
Lung Disorder Hospitalization 11/10/2005 Female 12/5/2007 Other Health Professional France
Primary
Concomitant
Tendon Rupture Disability 12/25/2006 57 Male 12/24/2007
Primary
Secondary
Drug Interaction Hospitalization 7/1/2007 77 Female 12/31/2007 Other Health Professional Spain
Primary
Concomitant
Interacting
Toxic Epidermal Necrolysis Hospitalization 12/2/2007 79 Female 1/22/2008 Consumer France
Primary
Secondary
Concomitant
Tendon Rupture Disability 12/25/2006 57 Male 1/16/2008 France
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 10/7/2007 74 Female 2/27/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Wound Infection 10/28/2007 79 Female 2/28/2008 Physician Netherlands
Primary
Concomitant
Shock Haemorrhagic Life Threatening 8/30/2007 61 Male 254 lb 2/22/2008 Physician France
Primary
Concomitant
Vomiting Hospitalization 12/1/2007 86 Female 3/18/2008 Physician Switzerland
Primary
Concomitant
Pruritus Other Serious 6/27/2007 68 Female 4/10/2008 Other Health Professional Spain
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/15/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Vomiting Life Threatening 2/22/2008 80 Female 4/18/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Vomiting Life Threatening 2/22/2008 80 Female 4/18/2008 Consumer Spain
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 12/1/2007 80 Male 4/15/2008 Other Health Professional Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/23/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Hepatic Neoplasm Malignant Life Threatening 4/25/2007 76 Male 165 lb 4/23/2008 Physician Bulgaria
Primary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 4/24/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Drug Interaction Life Threatening 10/7/2007 74 Female 4/24/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Life Threatening 2/22/2008 80 Female 4/29/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Vomiting Life Threatening 2/22/2008 80 Female 5/16/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Syncope Life Threatening 4/18/2008 67 Female 5/28/2008 Other Health Professional Denmark
Primary
Concomitant
Thrombocytopenia Death 7/7/2007 77 Male 6/6/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Wound Infection Other Serious 10/28/2007 79 Female 6/12/2008 Physician Netherlands
Primary
Concomitant
Cardiac Valve Disease Other Serious 6/3/2008 76 Female 7/3/2008 Consumer Spain
Primary
Concomitant
Somnolence Hospitalization 3/1/2008 84 Female 7/7/2008 Consumer Argentina
Primary
Concomitant
Tremor Disability 1/1/2007 Female 7/7/2008 Physician Switzerland
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 7/14/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Life Threatening 3/12/2008 81 Male 7/14/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Pleuropericarditis Death 12/22/2007 75 Female 7/16/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 7/18/2008 Consumer Spain
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/22/2008 80 Female 7/21/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Tremor Other Serious 1/1/2007 73 Male 154 lb 8/22/2008 Physician Greece
Primary
Secondary
Concomitant
Thyroid Function Test Abnormal Hospitalization 8/10/2008 77 Female 8/26/2008 Physician Spain
Primary
Concomitant
Hypotension Life Threatening 6/26/2008 83 Female 8/27/2008 Physician
Primary
Concomitant
Renal Failure Acute Hospitalization 4/7/2008 91 Female 9/8/2008
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/7/2008 9/12/2008 Consumer France
Primary
Secondary
Concomitant
Vomiting Hospitalization 3/16/2007 83 Female 9/30/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 6/1/2008 84 Male 10/31/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Septic Shock Death 2/4/2008 73 Male 11/10/2008 Physician Spain
Primary
Concomitant
Septic Shock Death 2/4/2008 73 Male 11/21/2008 Physician Spain
Primary
Concomitant
Renal Failure Acute Hospitalization 6/1/2008 84 Male 11/28/2008 Other Health Professional Spain
Primary
Concomitant
Interacting
Erythema Multiforme Other Serious 4/9/2008 62 Female 12/1/2008 Physician Spain
Primary
Concomitant
Anal Haemorrhage Hospitalization 83 Female 11/27/2008 Consumer Spain
Primary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 4/25/2007 76 Male 165 lb 12/4/2008 Physician Bulgaria
Primary
Concomitant
Right Ventricular Failure Hospitalization 4/24/2008 88 Female 12/11/2008 Physician Switzerland
Primary
Secondary
Concomitant
Septic Shock Death 2/4/2008 73 Male 176 lb 12/19/2008 Physician Spain
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/20/2008 Female 12/30/2008 Consumer Spain
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/20/2008 82 Female 1/5/2009 Consumer Spain
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 9/30/2008 86 Female 1/5/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 73 Male 154 lb 1/9/2009 Physician Greece
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 1/13/2009 Greece
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization 1/27/2001 80 Male 1/13/2009 Consumer Spain
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/30/2008 86 Female 1/13/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Hepatic Neoplasm Malignant Life Threatening 4/25/2007 76 Male 165 lb 1/19/2009 Physician Bulgaria
Primary
Concomitant
Nonspecific Reaction Life Threatening 12/7/2008 74 Female 1/22/2009 Other Health Professional France
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 9/30/2008 86 Female 1/21/2009 Pharmacist Denmark
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 10/28/2008 82 Male 2/2/2009 Other Health Professional France
Primary
Concomitant
Interacting
Rhabdomyolysis Other Serious 12/2/2008 87 Male 176 lb 2/5/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 1/1/2008 2/13/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Haematoma Life Threatening 6/14/2008 2/13/2009 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Serotonin Syndrome Other Serious 9/30/2008 86 Female 2/18/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Tendon Rupture Disability 12/25/2006 57 Male 3/3/2009
Primary
Secondary
Serotonin Syndrome Hospitalization 9/30/2008 86 Female 2/25/2009 Consumer Denmark
Primary
Secondary
Concomitant
Haemorrhage Hospitalization 12/2/2008 69 Female 3/5/2009 Consumer Spain
Primary
Concomitant
International Normalised Ratio Increased Other Serious 11/1/2008 88 Female 128 lb 3/16/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 1/1/2008 3/18/2009 Other Health Professional Spain
Primary
Concomitant
Interacting
Polypectomy Other Serious 6/5/2008 83 Male 4/2/2009 Other Health Professional Spain
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 1/22/2009 Male 4/1/2009 Other Health Professional Switzerland
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 3/5/2009 81 Male 4/3/2009 Spain
Primary
Concomitant
Weight Increased Hospitalization 12/16/2008 80 Female 3/30/2009 France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Life Threatening 3/5/2009 81 Male 4/9/2009 Spain
Primary
Concomitant
Right Ventricular Failure Hospitalization 12/16/2008 80 Female 3/30/2009 France
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 2/14/2009 80 Female 5/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Staphylococcal Bacteraemia Hospitalization 9/24/2008 Female 143 lb 5/19/2009 Physician Spain
Primary
Concomitant

Drug Data