Digoxin combined with Senna

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Somnolence Hospitalization 9/4/2005 89 Male 170 lb 1/10/2006 United States
Primary
Concomitant
Jaundice Cholestatic Hospitalization 3/28/2006 67 Female 173 lb 5/11/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 4/8/2006 Male 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 1/26/2006 82 Female 8/24/2006 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 5/23/2003 68 Male 194 lb 9/5/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/5/2006 96 Female 128 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Peripheral Ischaemia Hospitalization 1/1/2002 86 Male 11/14/2006 United Kingdom
Primary
Concomitant
Haemorrhage Other Serious 11/10/2006 86 Female 11/17/2006 Consumer United States
Primary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vaginal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Haemorrhoidal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/10/2006 80 Male 12/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/17/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/16/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/11/2007 Physician United Kingdom
Primary
Concomitant
Subdural Haematoma Life Threatening 10/18/2006 80 Male 191 lb 1/9/2007 Pharmacist United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Hospitalization 12/13/2006 91 Female 1/25/2007 Physician United Kingdom
Primary
Concomitant
Drug Interaction Life Threatening 2/8/2007 86 Female 3/1/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 2/8/2007 86 Female 3/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 11/3/2006 83 Male 173 lb 2/20/2007 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/24/2007 72 Male 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/3/2007 United Kingdom
Primary
Secondary
Concomitant
Dystonia Hospitalization 1/3/2007 68 Female 4/5/2007 United Kingdom
Primary
Secondary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Ulcer Hospitalization 3/1/2007 61 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 12/5/2006 79 Male 5/23/2007 Physician United States
Primary
Concomitant
Upper Limb Fracture Hospitalization 12/1/2004 94 Female 6/13/2007 United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 9/13/2007 Physician United States
Primary
Concomitant
Fracture Other Serious 94 Female 9/28/2007 Physician United Kingdom
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/7/2007 55 Male 10/11/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hip Fracture Other Serious 11/27/2006 Male 218 lb 12/26/2007 Consumer United Kingdom
Primary
Concomitant
Visual Disturbance Hospitalization 3/1/2007 63 Male 12/28/2007 Physician United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 3/1/2007 63 Male 1/9/2008 Physician United States
Primary
Secondary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 1/16/2008 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 6/9/2004 63 Male 1/28/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 3/26/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Hospitalization 12/29/2007 86 Female 143 lb 3/31/2008 Pharmacist United States
Primary
Secondary
Concomitant
Insomnia 80 Male 4/29/2008 Consumer United States
Primary
Concomitant
Right Ventricular Failure Other Serious 10/1/2007 70 Female 139 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 9/25/2007 67 Male 6/21/2008 Physician United States
Primary
Concomitant
Somnolence Death 9/25/2007 67 Male 6/26/2008 Physician United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 8/12/2008 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 1/9/2008 66 Female 125 lb 8/22/2008 United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 9/12/2008 Physician United States
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/25/2008
Primary
Concomitant
Skin Tightness Other Serious 12/1/2006 79 Male 187 lb 9/27/2008 Physician United States
Primary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 9/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 9/30/2008 Physician United States
Primary
Secondary
Concomitant
Erythema Multiforme Hospitalization 8/13/2008 78 Male 10/7/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Vomiting Required Intervention 9/9/2008 42 Female 11/6/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/15/2008 Male 218 lb 12/1/2008 Consumer United Kingdom
Primary
Concomitant
Product Quality Issue Other Serious 11/20/2008 81 Female 140 lb 12/5/2008 Consumer United States
Primary
Concomitant
Neuropathy Peripheral Other Serious 1/1/2008 Female 110 lb 2/20/2009 Physician United States
Primary
Concomitant
Hallucination, Visual Other Serious 3/13/2009 Female 106 lb 4/14/2009 Consumer United Kingdom
Primary
Concomitant
Urinary Tract Infection Life Threatening 12/31/2004 90 Female 114 lb 4/20/2009 United States
Primary
Concomitant
Hallucination, Visual Other Serious 3/13/2009 Female 4/17/2009 Other Health Professional United Kingdom
Primary
Concomitant
Haemorrhagic Stroke Life Threatening 4/2/2009 Female 105 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 8/13/2009 Lawyer United States
Primary
Concomitant
Loss Of Consciousness Death 8/19/2009 Male 8/19/2009 Pharmacist United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Urinary Tract Infection Bacterial Hospitalization 71 Female 12/1/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 71 Female 1/13/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious Male 2/26/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 71 Female 2/17/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 11/6/2009 86 Female 121 lb 12/2/2009 Pharmacist United States
Primary
Secondary
Concomitant
Pain Other Serious 2/1/2010 Male 183 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 3/18/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 71 Female 79 lb 3/25/2010 United States
Primary
Concomitant
Herpes Zoster Other Serious Female 4/13/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 12/28/2009 66 Male 4/16/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 71 Female 79 lb 4/26/2010 United States
Primary
Concomitant
Thrombocytopenia Other Serious 3/4/2008 52 Male 157 lb 5/14/2010 Lawyer United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/26/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Other Serious 4/18/2010 79 Female 5/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Wheezing 74 Female 5/28/2010 Consumer United States
Primary
Concomitant
Herpes Zoster Other Serious Female 5/28/2010 Other Health Professional United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 6/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 71 Female 79 lb 5/26/2010 Consumer United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 6/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 49 Female 5/27/2010 United States
Primary
Concomitant
Renal Failure Chronic Death 8/1/2009 75 Male 115 lb 6/10/2010 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 6/11/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization Male 6/15/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 73 Female 6/25/2010 United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2007 73 Male 150 lb 7/8/2010 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 73 Female 7/2/2010 United States
Primary
Concomitant
Pneumonia Hospitalization Male 7/16/2010 Consumer United States
Primary
Secondary
Concomitant
Thrombophlebitis Other Serious 3/1/2008 52 Male 157 lb 7/19/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 73 Female 7/12/2010 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 12/28/2009 66 Male 8/3/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 85 Female 7/26/2010 United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 1/1/2008 71 Female 160 lb 8/5/2010 Consumer United States
Primary
Concomitant
Petechiae 7/19/2010 95 Female 100 lb 7/30/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Other Serious 9/1/2007 73 Male 150 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 2/1/2010 Male 183 lb 9/16/2010 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 10/13/2006 65 Female 167 lb 9/3/2010 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2008 71 Female 160 lb 10/7/2010 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 8/19/2010 87 Male 10/12/2010 Pharmacist United States
Primary
Concomitant
Sputum Discoloured Hospitalization 9/30/2010 80 Male 10/20/2010 Other Health Professional United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 69 Female 11/10/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/1/2010 69 Female 12/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pain Other Serious 2/1/2010 Male 183 lb 3/10/2010 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Hospitalization 12/11/2010 74 Male 12/22/2010 Physician United States
Primary
Concomitant
Chills Other Serious 3/1/2008 52 Male 157 lb 1/14/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Disability 12/25/2010 84 Male 198 lb 1/21/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pain Hospitalization 1/11/2011 69 Male 2/3/2011 Pharmacist United States
Primary
Concomitant
Arrhythmia Hospitalization 1/21/2011 61 Male 222 lb 2/10/2011 Other Health Professional United States
Primary
Concomitant
Gingival Ulceration Death 7/12/2005 62 Female 2/17/2011 Lawyer United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 1/11/2011 69 Male 212 lb 2/22/2011 Pharmacist United States
Primary
Concomitant
Nodal Arrhythmia Hospitalization 12/27/2010 81 Female 146 lb 1/26/2011 Pharmacist United States
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 3/4/2011 Other Health Professional United Kingdom
Primary
Concomitant
Pruritus 2/1/2011 85 Female 3/9/2011 Consumer United States
Primary
Concomitant
Microangiopathy Hospitalization 89 Female 188 lb 3/7/2011 Lawyer United States
Primary
Concomitant
Scar Other Serious 7/12/2005 62 Female 3/21/2011 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 12/28/2009 66 Male 5/3/2011 Consumer United States
Primary
Secondary
Concomitant
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/20/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 1 Female 6/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/23/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 1 Female 6/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 6/22/2011 Other Health Professional Denmark
Primary
Concomitant
Drug Level Increased Hospitalization 4/20/2003 67 Female 7/4/2011 Other Health Professional United Kingdom
Primary
Secondary
Drug Level Increased Hospitalization 4/20/2003 67 Female 7/11/2011 Other Health Professional United Kingdom
Primary
Secondary
Overdose Hospitalization 4/20/2003 67 Female 7/14/2011 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Death 3/22/2011 73 Male 176 lb 7/18/2011 Physician United States
Primary
Secondary
Concomitant
Skin Hyperpigmentation Hospitalization 3/22/2011 73 Male 176 lb 7/20/2011 Physician United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Death 6/11/2011 89 Female 8/4/2011 Physician United States
Primary
Concomitant
Mobility Decreased Other Serious 4/14/2009 77 Female 141 lb 8/5/2011 Physician United States
Primary
Concomitant
Cholecystitis Acute Hospitalization 3/22/2011 73 Male 176 lb 8/8/2011 Physician United States
Primary
Concomitant
Hypomagnesaemia Hospitalization 6/29/2011 66 Male 9/4/2011 Physician United Kingdom
Primary
Concomitant
Weight Fluctuation Death 7/12/2005 62 Female 9/5/2011 Lawyer United States
Primary
Secondary
Concomitant
Death Death 1/1/2011 94 Female 9/27/2011 Other Health Professional United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 9/24/2011 89 Female 100 lb 9/30/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hypophagia Other Serious 9/23/2011 64 Female 11/8/2011 Physician United States
Primary
Concomitant
Respiratory Distress Death 1/1/2011 74 Female 11/9/2011 Physician United States
Primary
Concomitant
Bone Lesion Other Serious 7/12/2005 62 Female 11/11/2011 Physician United States
Primary
Secondary
Concomitant

Drug Data