Digoxin combined with Ranitidine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Delirium Other Serious 12/28/2005 82 Female 1/5/2006 Consumer Brazil
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/1/2005 57 Male 159 lb 1/19/2006 Pharmacist Canada
Primary
Concomitant
Interacting
Pulmonary Mass Life Threatening 11/10/2004 50 Male 146 lb 1/23/2005 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Toe Amputation Hospitalization 2/11/2002 65 Male 300 lb 2/21/2006 Lawyer United States
Primary
Concomitant
Cardiac Failure Death 9/17/1998 75 Male 3/13/2006 France
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/11/2002 65 Male 300 lb 3/30/2006 Lawyer United States
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 3/31/2006 Lawyer Poland
Primary
Concomitant
Tinnitus Hospitalization 8/1/2001 78 Female 4/7/2006 Physician Poland
Primary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 4/6/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Myocardial Infarction Hospitalization 9/21/2004 80 Male 165 lb 5/15/2006 Lawyer United States
Primary
Concomitant
Carotid Artery Occlusion Other Serious 5/14/2006 Male 156 lb 6/5/2006 Consumer United States
Primary
Concomitant
Respiratory Distress Other Serious 83 Male 370 lb 5/29/2006 Pharmacist United States
Primary
Secondary
Urinary Tract Infection Hospitalization 9/29/1996 63 Female 6/16/2006 Canada
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 9/29/1996 63 Female 6/26/2006 Canada
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/9/2005 80 Female 7/18/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Thrombocytopenia Hospitalization 10/9/2005 80 Female 7/19/2006 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Pyrexia Hospitalization 6/2/2006 76 Male 7/19/2006 Physician Italy
Primary
Concomitant
Drug Effect Decreased 1/1/2005 53 Male 188 lb 7/12/2006 Consumer United States
Primary
Concomitant
Weight Decreased 6/1/2005 Male 215 lb 8/8/2006 Consumer United States
Primary
Concomitant
Pulmonary Function Test Abnormal Hospitalization 4/15/2006 78 Female 134 lb 8/7/2006 Physician France
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 6/15/2000 67 Male 8/15/2006 France
Primary
Concomitant
Skin Exfoliation Other Serious 12/27/2005 55 Female 8/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred 7 Female 51 lb 7/24/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 9/15/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 9/12/2006 Other Health Professional Croatia (Local Name: Hrvatska)
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 9/19/2006 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death 9/17/1998 75 Male 9/21/2006 France
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 64 Female 10/6/2006 Physician Australia
Primary
Concomitant
Pulmonary Thrombosis Hospitalization 8/18/2006 50 Female 145 lb 10/6/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/5/2006 73 Male 165 lb 10/23/2006 Physician United Kingdom
Primary
Concomitant
Death Death 9/1/2006 84 Male 10/26/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Dyspnoea 6/1/2006 80 Male 11/13/2006 Consumer United States
Primary
Concomitant
Pulmonary Hypertension Death 10/23/2006 26 Female 137 lb 11/13/2006 Other Health Professional Brazil
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Death 9/29/2006 81 Female 143 lb 12/6/2006 Other Health Professional United Kingdom
Primary
Concomitant
Rash Morbilliform Other Serious 3/2/2006 78 Female 12/14/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 12/27/2006 Other Health Professional United States
Primary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred Female 51 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Fatigue 9/1/2006 85 Female 11/7/2006 Consumer United States
Primary
Concomitant
Platelet Count Decreased Death 9/29/2006 81 Female 143 lb 1/29/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Death 10/9/2005 80 Female 1/24/2007 Croatia (Local Name: Hrvatska)
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/2/2007 Other Health Professional United States
Primary
Concomitant
Hepatitis Required Intervention 1/2/2006 72 Male 138 lb 9/27/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/15/2006 60 Male 335 lb 12/19/2006 Pharmacist United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/10/2006 Male 215 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Hypertrophy Hospitalization 1/22/2007 49 Male 273 lb 2/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/12/2007 Other Health Professional United States
Primary
Concomitant
Hypotension Hospitalization 12/2/2006 Male 2/13/2007 Pharmacist United States
Primary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 3/19/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Fatigue Hospitalization 1/17/2007 70 Female 159 lb 4/5/2007 Consumer United States
Primary
Secondary
Concomitant
Rectal Haemorrhage Hospitalization 10/26/2006 69 Male 11/3/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 4/27/2007 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 5/2/2007 Physician United States
Primary
Concomitant
Cardiac Arrest Life Threatening 3/14/2007 Female 176 lb 5/4/2007 Physician Canada
Primary
Concomitant
Cardiac Arrest Life Threatening 3/14/2007 Female 176 lb 5/10/2007 Physician Canada
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Urticaria Hospitalization 12/16/2006 59 Female 93 lb 5/14/2007 Physician Hungary
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 74 Male 5/4/2007 Other Health Professional Spain
Primary
Concomitant
Hyperglycaemia Other Serious 6/26/2006 87 Male 158 lb 4/26/2007 United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Other Serious 68 Female 6/22/2007 Physician United States
Primary
Secondary
Concomitant
Urticaria Hospitalization 12/16/2006 59 Female 93 lb 6/22/2007 Physician Hungary
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/22/2003 Female 128 lb 7/6/2007 Other Health Professional Australia
Primary
Concomitant
Weight Decreased Other Serious 4/13/2007 79 Female 106 lb 7/10/2007 Other Health Professional United States
Primary
Concomitant
Rhinorrhoea Death 1/22/2003 Male 148 lb 7/11/2007 Other Health Professional Australia
Primary
Concomitant
Movement Disorder Life Threatening 7/1/2007 85 Male 7/13/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 11/22/2003 Female 128 lb 8/14/2007 Other Health Professional Australia
Primary
Concomitant
Cardiac Arrest Life Threatening 3/14/2007 Female 176 lb 8/24/2007 Physician Canada
Primary
Concomitant
Pulmonary Oedema Other Serious 8/4/2007 58 Female 291 lb 8/24/2007 Consumer United Kingdom
Primary
Concomitant
Nausea Hospitalization 5/29/2007 Male 123 lb 8/27/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 3/14/2007 68 Female 176 lb 9/10/2007 Physician Canada
Primary
Concomitant
Death Death 9/1/2006 Male 9/14/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Other Serious 7/28/2007 58 Female 291 lb 9/19/2007 Physician United Kingdom
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Response Decreased Other Serious 83 Male 10/10/2007 Physician Australia
Primary
Concomitant
Pulmonary Fibrosis Other Serious 83 Male 10/8/2007 Australia
Primary
Concomitant
Polyp Other Serious 3 Male 11/2/2007
Primary
Secondary
Pulmonary Oedema Hospitalization 2/7/2007 76 Male 288 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 1/15/2007 83 Male 11/8/2007 Physician Australia
Primary
Concomitant
Insomnia 8/1/2007 76 Male 201 lb 11/19/2007 United States
Primary
Concomitant
Renal Impairment Life Threatening 12/10/2007 Female 168 lb 1/17/2008 Other Health Professional United States
Primary
Concomitant
Drug Administration Error Disability 1/29/2007 82 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Vision Blurred 7/1/2006 68 Male 3/3/2008 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 7/28/1997 65 Female 3/6/2008 Belgium
Primary
Concomitant
Interacting
Mass 1/1/2008 Female 114 lb 3/15/2008 Consumer United States
Primary
Concomitant
Dyspnoea Hospitalization 3/7/2008 67 Female 4/1/2008 Physician Thailand
Primary
Secondary
Concomitant
Pyrexia Hospitalization 3/19/2008 74 Female 4/1/2008 Pharmacist United States
Primary
Concomitant
Medical Device Complication Other Serious 3/25/2008 2 Female 35 lb 4/21/2008 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased Other Serious 11/1/2007 79 Male 4/21/2008 United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/10/2003 85 Female 168 lb 4/29/2008 Pharmacist United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Brain Injury Other Serious 3/25/2008 2 Female 35 lb 4/28/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Ischaemic Hepatitis Hospitalization 5/2/2008 49 Male 5/30/2008 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Weight Increased 1/1/2001 Male 163 lb 5/30/2008 Consumer United States
Primary
Concomitant
Ischaemic Hepatitis Hospitalization 5/2/2008 49 Male 6/12/2008 Other Health Professional Russian Federation
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/14/2008 76 Female 6/27/2008 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 5/14/2008 76 Female 7/7/2008 United Kingdom
Primary
Concomitant
Vomiting Other Serious 49 Male 250 lb 8/12/2008 United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/19/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Sinus Bradycardia Hospitalization 5/15/2008 73 Female 8/22/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 9/7/1995 Male 206 lb 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Hospitalization 1/21/2008 Male 9/9/2008 United States
Primary
Concomitant
Pain 6/27/2008 Male 210 lb 9/12/2008 Consumer United States
Primary
Concomitant
Cardiac Failure Hospitalization 1/1/2008 Male 176 lb 9/15/2008 Netherlands
Primary
Concomitant
Insomnia 8/1/2007 76 Male 210 lb 7/23/2008 United States
Primary
Concomitant
Oesophageal Ulcer Hospitalization 5/15/2008 73 Female 119 lb 9/18/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 87 Female 160 lb 10/2/2008 Consumer United States
Primary
Concomitant
Weight Increased 1/1/2001 Male 163 lb 10/2/2008 Consumer
Primary
Concomitant
Walking Aid User Hospitalization 83 Male 175 lb 9/25/2008 United States
Primary
Concomitant
Product Quality Issue 3/18/2008 66 Male 10/30/2008 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Renal Failure Required Intervention 6/19/2008 82 Male 245 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Nausea 8/1/2008 Female 220 lb 11/26/2008 United States
Primary
Concomitant
Vision Blurred Hospitalization 65 Female 11/21/2008 United States
Primary
Concomitant
Haemoglobin Decreased Life Threatening 10/21/2008 86 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 3/10/2003 85 Female 185 lb 12/4/2008 Pharmacist United States
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/28/2008 United Kingdom
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 3/10/2003 85 Female 168 lb 12/12/2008 Pharmacist United States
Primary
Concomitant
Respiratory Disorder Death 80 Male 12/18/2008 Physician Canada
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 11/1/2008 Male 185 lb 12/22/2008 Consumer United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 11/1/2008 Male 185 lb 1/7/2009 Consumer United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 12/3/2008 United States
Primary
Secondary
Concomitant
Cardiac Failure Hospitalization 1/1/2008 Male 176 lb 1/16/2009 Netherlands
Primary
Concomitant
Cardiac Failure Hospitalization 1/1/2008 Male 176 lb 1/29/2009 Netherlands
Primary
Concomitant
Atrial Fibrillation Required Intervention 5/7/2008 85 Male 175 lb 5/8/2008 Pharmacist United States
Primary
Concomitant
Thinking Abnormal Other Serious 10/28/2007 73 Female 3/3/2009 Consumer Malaysia
Primary
Concomitant
Weight Decreased Other Serious Male 3/6/2009 Consumer United Kingdom
Primary
Concomitant
Vertigo Hospitalization 64 Male 4/23/2009 United States
Primary
Concomitant
Leukopenia Death 4/29/2009 Male 4/30/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Disability 81 Female 4/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 2/14/2003 43 Male 210 lb 5/19/2009 United States
Primary
Concomitant
Vertigo Other Serious 66 Female 5/13/2009 Lawyer United States
Primary
Concomitant
Musculoskeletal Chest Pain Hospitalization 65 Male 5/19/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 59 Male 215 lb 6/1/2009 United States
Primary
Concomitant
Renal Failure Other Serious 94 Female 113 lb 6/11/2009 Consumer United States
Primary
Concomitant
Renal Failure Life Threatening 57 Female 6/17/2009 United States
Primary
Concomitant

Drug Data