Digoxin combined with Protamine Sulfate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Wound Secretion Other Serious 8/1/2004 74 Female 114 lb 6/29/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 115 lb 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Intracardiac Thrombus Life Threatening 67 Female 117 lb 6/26/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization Male 116 lb 7/11/2007 Physician Japan
Primary
Concomitant
Mediastinitis Hospitalization 10/27/2006 Male 116 lb 8/10/2007 Physician Japan
Primary
Concomitant
Post Procedural Haemorrhage Required Intervention 11/7/2007 71 Male 146 lb 11/12/2007 Physician Germany
Primary
Concomitant
Procedural Complication Death 4/21/2008 65 Male 205 lb 5/9/2008 Pharmacist United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Ventricular Hypokinesia Life Threatening 6/2/2004 6 Male 11/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Troponin Increased Death 11/1/2008 Male 188 lb 3/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Hypercholesterolaemia Other Serious 10/14/2007 59 Female 12/22/2009 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 1/25/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 163 lb 4/16/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2008 1 Male 26 lb 6/15/2010 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 2/6/2008 51 Male 163 lb 9/21/2010 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 10/7/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 2/20/2007 69 Female 139 lb 12/2/2010 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 11/23/2010 Lawyer United States
Primary
Concomitant
Emotional Distress Other Serious 5/30/2007 80 Female 127 lb 2/28/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 9/30/2006 65 Female 126 lb 3/4/2011 Other Health Professional United States
Primary
Concomitant
Septic Shock Other Serious 9/28/2007 44 Male 178 lb 3/7/2011 Consumer United States
Primary
Secondary
Concomitant
Anxiety Death 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 10/8/2004 45 Female 110 lb 3/10/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Other Serious 10/4/2005 2 Female 29 lb 3/11/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious 10/4/2005 2 Female 29 lb 3/11/2011 Lawyer United States
Primary
Concomitant
Pain Death 5/18/2005 79 Male 178 lb 3/16/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 4/1/2003 56 Male 155 lb 3/17/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 12/31/2001 Male 6 lb 3/18/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 12/31/2001 Male 6 lb 3/18/2011 Other Health Professional United States
Primary
Concomitant
Renal Cyst Hospitalization 1/2/2003 76 Male 184 lb 3/21/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 1/2/2003 76 Male 184 lb 3/21/2011 Consumer United States
Primary
Concomitant
Renal Impairment Death 1/1/2005 76 Female 120 lb 3/22/2011 Consumer United States
Primary
Concomitant
Renal Failure Acute Other Serious 6/18/2001 70 Male 188 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 6/18/2001 70 Male 188 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Lawyer United States
Primary
Concomitant
Renal Failure Hospitalization 2/1/2000 52 Male 235 lb 3/22/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 3/5/2007 68 Male 220 lb 3/29/2011 Lawyer United States
Primary
Concomitant
Pain Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 3/5/2007 68 Male 220 lb 3/29/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 4/15/2004 71 Female 123 lb 3/29/2011 Consumer United States
Primary
Concomitant
Anxiety Hospitalization 9/30/2005 82 Female 120 lb 3/29/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 1/1/2005 68 Female 162 lb 3/31/2011 Other Health Professional United States
Primary
Concomitant
Fear Death 1/1/2005 68 Female 162 lb 3/31/2011 Lawyer United States
Primary
Concomitant
Pain Death 8/3/2007 73 Female 130 lb 3/31/2011 Other Health Professional United States
Primary
Concomitant
Death Death 8/3/2007 73 Female 130 lb 3/31/2011 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Other Serious 9/9/2006 45 Female 120 lb 4/4/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 12/26/2000 59 Male 110 lb 4/5/2011 Consumer United States
Primary
Concomitant
Pain Death 9/7/1998 80 Male 174 lb 4/5/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 9/7/1998 80 Male 174 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 12/26/2000 59 Male 110 lb 4/5/2011 Other Health Professional United States
Primary
Concomitant
Pain Other Serious 1/28/2004 61 Female 126 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Depression Other Serious 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 1/22/2005 61 Female 161 lb 4/7/2011 Lawyer United States
Primary
Concomitant
Injury Death 1/1/2003 44 Male 258 lb 4/7/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Other Serious 1/22/2005 61 Female 161 lb 4/7/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 2/6/2004 62 Female 126 lb 4/8/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Death 9/1/2003 85 Female 368 lb 4/11/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 9/21/2005 48 Male 249 lb 4/12/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death 12/3/2005 61 Male 185 lb 4/12/2011 Lawyer United States
Primary
Concomitant
Stress Death 1/1/2005 68 Female 162 lb 4/14/2011 Consumer United States
Primary
Concomitant
Mental Disorder Other Serious 3/9/2007 58 Male 198 lb 4/15/2011 Lawyer United States
Primary
Concomitant
Death Other Serious 8/15/2003 76 Female 140 lb 4/15/2011 Other Health Professional United States
Primary
Concomitant
Nervousness Other Serious 1/3/2007 46 Male 224 lb 4/15/2011 Consumer United States
Primary
Concomitant
Confusional State Other Serious 11/1/2007 58 Male 137 lb 4/18/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Pain Death 12/26/2004 54 Male 205 lb 4/18/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 1/1/2005 52 Female 106 lb 4/20/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 1/1/2006 71 Male 180 lb 4/21/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Hospitalization 11/12/2005 75 Female 168 lb 4/23/2011 Other Health Professional United States
Primary
Concomitant
Convulsion Hospitalization 12/31/2001 0 Male 6 lb 4/22/2011 Consumer United States
Primary
Concomitant
General Physical Health Deterioration Other Serious 0 Male 36 lb 4/25/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 6/22/2007 74 Female 138 lb 4/27/2011 Consumer United States
Primary
Concomitant
Renal Injury Other Serious 10/28/2005 76 Female 49 lb 4/27/2011 Other Health Professional United States
Primary
Concomitant
Fear Other Serious 1/27/2003 64 Male 310 lb 4/29/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 12/31/2004 57 Male 251 lb 5/2/2011 Consumer United States
Primary
Concomitant
Fear Death 12/26/2004 54 Male 205 lb 4/29/2011 Consumer United States
Primary
Concomitant
Pain Death 1/1/2007 73 Female 168 lb 5/2/2011 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 5/9/2001 76 Female 200 lb 5/2/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Pain Other Serious 9/1/2003 66 Male 188 lb 5/5/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 10/11/2005 80 Female 121 lb 5/6/2011 Consumer United States
Primary
Concomitant
Renal Impairment Life Threatening 8/1/2004 74 Female 114 lb 5/5/2011 Consumer United States
Primary
Secondary
Concomitant
Psychiatric Symptom Other Serious 1/1/2000 47 Female 152 lb 5/7/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Death 9/28/2007 44 Male 178 lb 5/7/2011 Lawyer United States
Primary
Concomitant
Pain Death 12/6/2001 85 Female 150 lb 5/9/2011 Other Health Professional United States
Primary
Concomitant
Renal Injury Hospitalization 8/1/2004 74 Female 114 lb 5/10/2011 Consumer Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 6/9/2007 62 Male 218 lb 5/11/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Other Serious 79 Female 104 lb 5/11/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/13/2006 77 Female 126 lb 5/12/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 6/17/2003 79 Female 198 lb 5/12/2011 Consumer United States
Primary
Concomitant
Anxiety Hospitalization 6/9/2007 62 Male 218 lb 5/17/2011 Other Health Professional United States
Primary
Concomitant
Anhedonia Other Serious 40 Male 134 lb 5/17/2011 Consumer United States
Primary
Concomitant
Stress Other Serious 12/1/2006 59 Male 180 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Death 8/1/1996 17 Male 97 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Renal Impairment Hospitalization 4/8/2003 70 Female 144 lb 5/18/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 3/9/2005 66 Male 229 lb 5/19/2011 Consumer United States
Primary
Concomitant
Pain Death 8/1/2006 66 Female 254 lb 5/19/2011 Consumer United States
Primary
Concomitant
Anxiety Death Male 192 lb 5/20/2011 Other Health Professional United States
Primary
Concomitant
Renal Failure Hospitalization 2/19/2000 70 Male 175 lb 5/21/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 6/17/2003 79 Female 198 lb 5/21/2011 Lawyer United States
Primary
Concomitant
Depression Death Male 185 lb 5/21/2011 Consumer United States
Primary
Concomitant
Fear Other Serious 10/1/2002 63 Male 293 lb 5/23/2011 Other Health Professional United States
Primary
Concomitant
Injury Hospitalization 2/4/2004 75 Female 145 lb 5/23/2011 Other Health Professional United States
Primary
Concomitant
Pain Death 10/4/2005 2 Female 29 lb 5/25/2011 Consumer United States
Primary
Concomitant
Death Death 1/12/2001 16 Male 115 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Death 2/26/2003 48 Female 123 lb 5/26/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 8/27/2002 81 Female 161 lb 5/26/2011 Consumer United States
Primary
Concomitant
Depression Death 7/15/2007 30 Male 5/28/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 5/13/2005 79 Male 188 lb 5/31/2011 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2007 69 Female 125 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 53 Male 190 lb 6/1/2011 Other Health Professional United States
Primary
Concomitant
Injury Other Serious 6/24/2007 81 Female 139 lb 6/1/2011 Lawyer United States
Primary
Concomitant
Diabetes Mellitus Hospitalization 61 Male 172 lb 6/2/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 10/12/2003 79 Female 117 lb 6/3/2011 Physician United States
Primary
Concomitant
Renal Failure Disability 83 Male 146 lb 6/3/2011 Other Health Professional United States
Primary
Concomitant
Anxiety Hospitalization 10/16/2006 64 Male 186 lb 6/3/2011 Lawyer United States
Primary
Concomitant
Renal Failure Other Serious 10/8/1999 58 Male 227 lb 6/4/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 11/20/2004 23 Female 135 lb 6/4/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Other Serious 2/1/2001 59 Female 143 lb 6/4/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 1/11/2001 67 Female 185 lb 6/4/2011 Consumer United States
Primary
Concomitant
Emotional Distress Other Serious 1/15/2007 67 Male 181 lb 6/6/2011 Other Health Professional United States
Primary
Concomitant
Injury Death 4/30/2004 0 Female 30 lb 6/6/2011 Consumer United States
Primary
Concomitant
Pain Other Serious 12/18/2001 38 Male 179 lb 6/7/2011 Lawyer United States
Primary
Concomitant
Emotional Distress Other Serious 6/24/2005 75 Female 158 lb 6/7/2011 Other Health Professional United States
Primary
Concomitant
Death Death 9/8/2007 75 Female 180 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Anhedonia Death 1/22/2005 61 Female 161 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Anhedonia Hospitalization 12/18/2006 64 Male 130 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Pain Other Serious 9/13/1999 53 Male 161 lb 6/10/2011 Lawyer United States
Primary
Concomitant
Depression Other Serious 5/5/2003 34 Male 160 lb 6/11/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 10/2/2005 68 Male 227 lb 6/11/2011 Consumer United States
Primary
Concomitant
Stress Death 6/22/2005 71 Female 158 lb 6/15/2011 Lawyer United States
Primary
Concomitant
Stress Other Serious 8/9/1996 47 Male 256 lb 6/16/2011 Consumer United States
Primary
Concomitant
Injury Hospitalization 4/2/2005 54 Male 195 lb 6/16/2011 Consumer United States
Primary
Concomitant
Multi-organ Failure Other Serious 61 Male 182 lb 6/16/2011 Consumer United States
Primary
Concomitant
Depression Other Serious 8/27/2002 81 Female 161 lb 6/16/2011 Lawyer United States
Primary
Concomitant
Unevaluable Event Other Serious 7/8/2005 78 Male 207 lb 6/16/2011 Lawyer United States
Primary
Concomitant
Injury Other Serious 64 Male 190 lb 6/17/2011 Lawyer United States
Primary
Concomitant
Anxiety Other Serious 64 Male 190 lb 6/18/2011 Consumer United States
Primary
Concomitant
Injury Other Serious 1/20/2007 77 Male 146 lb 6/23/2011 Physician United States
Primary
Concomitant
Injury Death 11/6/2007 55 Male 172 lb 6/21/2011 Lawyer United States
Primary
Concomitant
Disability Hospitalization 3/9/2007 58 Male 198 lb 6/28/2011 Other Health Professional United States
Primary
Concomitant
Stress Death 8/9/2005 57 Female 237 lb 6/23/2011 Other Health Professional United States
Primary
Concomitant
Emotional Distress Other Serious 4/5/2002 49 Male 172 lb 6/23/2011 Lawyer United States
Primary
Concomitant

Drug Data