Digoxin combined with Morphine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 8/23/2005 42 Female 154 lb 1/9/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Stent Occlusion Hospitalization 7/25/2005 64 Male 183 lb 1/12/2006 Poland
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 1/17/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 8/23/2005 43 Female 154 lb 1/17/2006 Switzerland
Primary
Secondary
Concomitant
Epistaxis Hospitalization 12/1/2003 4 Female 22 lb 10/6/2005 Physician France
Primary
Concomitant
Hepatic Failure Death 81 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Cardiogenic Shock Other Serious 10/9/2005 82 Female 2/17/2006 Physician Greece
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 2/26/2001 54 Female 146 lb 3/30/2006 Physician United States
Primary
Secondary
Concomitant
Cardiogenic Shock Other Serious 10/9/2005 82 Female 3/27/2006 Other Health Professional Greece
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 8/23/2005 42 Female 154 lb 4/3/2006 Consumer Switzerland
Primary
Secondary
Concomitant
Unresponsive To Pain Stimuli Hospitalization 8/23/2005 42 Female 154 lb 4/10/2006 Switzerland
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Unresponsive To Verbal Stimuli Life Threatening 4/28/2006 Female 105 lb 6/20/2006 Pharmacist United States
Primary
Concomitant
Scrotal Operation Required Intervention 11/17/2005 46 Male 8/15/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 8/18/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Death 1/22/2006 66 Female 8/23/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Time Prolonged Other Serious 8/17/2006 Female 8/28/2006 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2006 Female 88 lb 9/1/2006 Physician United States
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 67 Male 132 lb 9/14/2006 Physician Canada
Primary
Concomitant
Activated Partial Thromboplastin Time Prolonged Other Serious 8/17/2006 Female 9/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 163 lb 9/12/2006 Other Health Professional United States
Primary
Concomitant
Streptococcal Infection Hospitalization 10/8/2005 66 Female 9/13/2006 United States
Primary
Secondary
Concomitant
Bronchopneumonia Hospitalization 60 Male 9/14/2006 Other Health Professional Sweden
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/25/2006 Male 203 lb 4/26/2006 Pharmacist United States
Primary
Concomitant
Multiple Myeloma Hospitalization 8/17/2006 63 Male 9/18/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Death 1/22/2006 66 Female 9/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Bacterial Required Intervention 6/30/2006 62 Female 9/21/2006 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 9/5/2006 68 Female 131 lb 10/27/2006 Physician United States
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/21/2005 74 Male 11/15/2006 United States
Primary
Secondary
Concomitant
Laboratory Test Interference Other Serious 8/17/2006 Female 11/7/2006 Physician United States
Primary
Secondary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 11/28/2006 Physician Canada
Primary
Concomitant
Hepatic Failure Hospitalization 8/25/2006 63 Male 11/28/2006 Physician United States
Primary
Concomitant
Respiratory Distress Life Threatening 8/14/2005 83 Female 197 lb 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Resorption Bone Increased Other Serious 3/8/2006 67 Male 12/20/2006 Pharmacist United States
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 77 Male 132 lb 12/22/2006 Physician Canada
Primary
Concomitant
Ventricular Fibrillation Death 1/25/2006 69 Male 10/6/2006 United States
Primary
Secondary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Cor Pulmonale Chronic Death 9/18/2006 74 Female 132 lb 10/24/2006 Other Health Professional United States
Primary
Concomitant
Vertebroplasty Other Serious 11/24/2006 78 Female 1/15/2007 Consumer Canada
Primary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 1/17/2007 Physician Australia
Primary
Secondary
Concomitant
Tachycardia Life Threatening 11/30/2006 80 Female 181 lb 1/25/2007 Pharmacist United States
Primary
Concomitant
Perirectal Abscess Hospitalization 9/5/2006 68 Female 131 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Perirectal Abscess Hospitalization 9/5/2006 68 Female 131 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 2/12/2007 Physician Bulgaria
Primary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 2/15/2007 Physician Australia
Primary
Secondary
Concomitant
Paraesthesia Other Serious 9/1/2006 76 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Troponin I Increased Life Threatening 1/14/2007 76 Female 150 lb 3/2/2007 Physician Australia
Primary
Secondary
Concomitant
Resorption Bone Increased Other Serious 3/8/2006 67 Male 3/15/2007 Pharmacist United States
Primary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 3/16/2007 Physician Bulgaria
Primary
Concomitant
Interstitial Lung Disease Death 1/24/2000 89 Male 152 lb 8/9/2005 Physician United States
Primary
Concomitant
Interstitial Lung Disease Death 1/24/2005 89 Male 152 lb 8/9/2005 Pharmacist United States
Primary
Concomitant
Vertebroplasty Other Serious 1/1/2006 78 Female 3/14/2007 Consumer Canada
Primary
Concomitant
Delusion Of Replacement Death 77 Female 3/23/2007
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 4/6/2007 Physician Bulgaria
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Somnolence Hospitalization 3/19/2007 68 Female 99 lb 5/4/2007 Other Health Professional France
Primary
Secondary
Concomitant
Diverticulitis Hospitalization 4/24/2007 Male 173 lb 5/9/2007 Physician United States
Primary
Secondary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/15/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/24/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 5/31/2007 Physician United States
Primary
Secondary
Concomitant
Diverticulitis Life Threatening 4/24/2007 Male 173 lb 6/20/2007 Physician United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 7/16/2007 Physician Bulgaria
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/1/2007 78 Female 8/9/2007 Consumer Spain
Primary
Concomitant
Sepsis Hospitalization 7/11/2006 88 Male 8/9/2007 United States
Primary
Concomitant
Pneumonia Hospitalization 7/1/2007 72 Female 9/10/2007 Consumer Spain
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Respiratory Failure Hospitalization 9/11/2007 84 Female 10/4/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 2/12/2007 63 Male 176 lb 11/13/2007 Physician United States
Primary
Concomitant
Traumatic Haematoma Other Serious 5/10/2007 79 Female 11/20/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 5/15/2007 79 Female 11/26/2007 Physician Switzerland
Primary
Secondary
Concomitant
Interacting
Ventricular Tachycardia Death 10/15/2007 76 Male 183 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Pulmonary Embolism Life Threatening 10/3/2007 88 Female 1/25/2008 Physician Sweden
Primary
Secondary
Concomitant
Road Traffic Accident Other Serious 67 Female 2/5/2008 Physician United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 7/26/2007 76 Male 210 lb 10/10/2007 Pharmacist United States
Primary
Secondary
Concomitant
Dyspnoea Hospitalization 3/7/2008 67 Female 4/1/2008 Physician Thailand
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Vomiting Death 3/17/2008 74 Female 5/12/2008 Consumer United States
Primary
Concomitant
Vomiting Projectile Death 3/18/2008 Female 5/5/2008 Consumer United States
Primary
Concomitant
Medication Error Required Intervention Male 6/5/2008 Other Health Professional United States
Primary
Concomitant
Vena Cava Injury Death 2/8/2008 Female 180 lb 6/10/2008 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 64 Male 5/23/2008 United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/1/2008 66 Female 6/16/2008 Consumer United States
Primary
Secondary
Concomitant
Death Death 9/25/2007 67 Male 6/21/2008 Physician United States
Primary
Concomitant
Somnolence Death 9/25/2007 67 Male 6/26/2008 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 71 Female 175 lb 6/17/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 7/31/2008 United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Weight Decreased 47 Female 8/20/2008 Canada
Primary
Secondary
Urine Output Decreased Hospitalization 9/7/1995 Male 206 lb 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Somnolence Death 3/19/2007 Female 9/5/2008 Physician France
Primary
Concomitant
Interacting
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Disease Progression Hospitalization 8/27/2008 Female 126 lb 9/16/2008 France
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Other Serious 2/6/2008 51 Male 9/17/2008 Lawyer United States
Primary
Concomitant
Weight Decreased 47 Female 9/18/2008 Canada
Primary
Secondary
International Normalised Ratio Increased Hospitalization 8/18/2002 74 Female 137 lb 9/20/2002 Pharmacist United States
Primary
Concomitant
Cardiac Arrest Other Serious Male 10/8/2008
Primary
Secondary
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
No Adverse Event 3/19/2007 68 Female 99 lb 11/5/2008 Other Health Professional France
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 65 Female 11/21/2008 United States
Primary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Underdose Death 1/1/2008 Male 198 lb 1/5/2009 Other Health Professional France
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 71 Male 1/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 11/28/2008 Female 119 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Propofol Infusion Syndrome Other Serious 67 Male 168 lb 1/15/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 71 Male 1/15/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Hospitalization 58 Female 1/28/2009 Consumer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 1/27/2009 74 Male 157 lb 1/29/2009 Pharmacist United States
Primary
Concomitant
Drug Toxicity Death Male 138 lb 2/3/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/16/2008 79 Male 2/23/2009 Physician United Kingdom
Primary
Concomitant
Troponin Increased Death 11/1/2008 Male 188 lb 3/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 3/24/2009 Netherlands
Primary
Concomitant
Interacting
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Death 3/18/2009 18 Female 44 lb 3/31/2009 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 4/1/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 3/31/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Renal Failure Hospitalization 3/21/2009 88 Male 154 lb 4/8/2009 Spain
Primary
Concomitant
Serotonin Syndrome Other Serious 4/10/2009 Physician Netherlands
Primary
Concomitant
Interacting
Pleural Effusion Other Serious 3/25/2009 65 Female 190 lb 4/3/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tooth Erosion Hospitalization 71 Male 4/17/2009 Consumer United States
Primary
Secondary
Concomitant
Subdural Haematoma Required Intervention 4/1/2009 85 Male 141 lb 4/15/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Death 3/18/2009 18 Female 44 lb 4/15/2009 Physician United States
Primary
Concomitant
Pruritus Disability 10/15/2008 Female 108 lb 4/23/2009 Physician United States
Primary
Concomitant
Intraventricular Haemorrhage Death 2/22/2009 58 Male 187 lb 4/29/2009 Physician Spain
Primary
Concomitant
Renal Failure Acute Life Threatening 2/14/2009 80 Female 5/13/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 54 Male 5/22/2009 United States
Primary
Concomitant

Drug Data