Digoxin combined with Metronidazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 198 lb 2/8/2006
Primary
Concomitant
Wound Necrosis Death 1/1/2006 69 Male 2/6/2006 Physician United States
Primary
Concomitant
Restlessness Hospitalization 1/10/2006 78 Male 2/10/2006 United Kingdom
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Dysfunction Hospitalization 1/15/2006 78 Female 3/28/2006 Physician France
Primary
Secondary
Concomitant
Torsade De Pointes Life Threatening 11/20/2005 65 Male 176 lb 4/5/2006
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Mesenteric Vein Thrombosis Life Threatening 12/28/2005 Female 94 lb United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/25/2006 Physician United Kingdom
Primary
Concomitant
Orthostatic Hypotension Other Serious 2/1/2005 Female 134 lb 5/23/2006 United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 7/14/2006 Physician United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 8/4/2006 Physician United Kingdom
Primary
Concomitant
Treatment Noncompliance Required Intervention 5/3/2006 67 Female 8/16/2006 Physician United States
Primary
Concomitant
Pathogen Resistance Other Serious 7/11/2006 53 Male 8/25/2006 Denmark
Primary
Secondary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Thrombocytopenia Hospitalization 3/26/2006 86 Male 119 lb 9/27/2006 Physician United States
Primary
Secondary
Concomitant
Paraesthesia Other Serious 9/1/2006 76 Female 134 lb 2/22/2007 Pharmacist United States
Primary
Secondary
Concomitant
Purpura Life Threatening 10/19/2006 72 Male 3/23/2007
Primary
Concomitant
Thrombocythaemia Other Serious 10/30/2006 88 Female 110 lb 6/11/2007 Other Health Professional Portugal
Primary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Sepsis Life Threatening 6/22/2007 88 Female 9/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/22/2007 88 Female 9/21/2007 Pharmacist Germany
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/22/2007 88 Female 9/26/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 9/26/2007 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 8/6/2007 Male 184 lb 10/5/2007 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 8/3/2007 64 Male 11/5/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 11/12/2007 United Kingdom
Primary
Secondary
Concomitant
Urinary Tract Infection Life Threatening 1/1/2007 Female 152 lb 11/19/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 10/15/2007 76 Male 183 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 11/4/2007 43 Male 238 lb 11/30/2007 Pharmacist Canada
Primary
Secondary
Concomitant
Skin Turgor Decreased Hospitalization 2/11/2007 82 Female 11/28/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 8/3/2007 2/12/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Hepatitis Other Serious 8/3/2007 64 Male 2/6/2008 United Kingdom
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 12/15/2004 59 Male 3/7/2008 Physician Germany
Primary
Secondary
Therapeutic Agent Toxicity Hospitalization 2/28/2008 74 Male 174 lb 8/28/2008 United States
Primary
Secondary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 9/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Myoclonus Other Serious 8/19/2008 34 Male 112 lb 8/21/2008 Other Health Professional United States
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Visual Impairment Other Serious 4/21/2008 Male 36 lb 11/4/2008 Pharmacist Brazil
Primary
Concomitant
Overdose Other Serious 12/8/2007 Male 176 lb 11/17/2008 Other Health Professional
Primary
Secondary
Concomitant
Death Death 5/23/2007 Male 11/18/2008 Korea, Republic Of
Primary
Concomitant
Overdose Other Serious 12/8/2007 Male 176 lb 12/10/2008 Other Health Professional
Primary
Secondary
Concomitant
Splenic Abscess Hospitalization 3/26/2006 87 Male 119 lb 12/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 31 Female 12/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 31 Female 12/16/2008 United Kingdom
Primary
Secondary
Urinary Tract Infection Hospitalization 31 Female 12/8/2008 United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 31 Female 12/19/2008 Consumer United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 31 Female 12/22/2008 Other Health Professional United Kingdom
Primary
Secondary
Thrombocytopenia Hospitalization 31 Female 1/8/2009 Consumer United Kingdom
Primary
Secondary
Hepatitis Acute Other Serious Male 1/15/2009 Physician Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/12/2009 Physician Germany
Primary
Secondary
Concomitant
Hepatitis Acute Other Serious Male 1/16/2009 Other Health Professional Germany
Primary
Secondary
Hepatitis Acute Other Serious Male 1/16/2009 Germany
Primary
Secondary
Sepsis Death 5/6/2007 Male 2/9/2009 Physician Korea, Republic Of
Primary
Concomitant
Venoocclusive Liver Disease Life Threatening 12/28/2008 62 Male 2/9/2009 Physician United States
Primary
Secondary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Ototoxicity Other Serious 51 Female 315 lb 3/16/2009
Primary
Secondary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Skin Discolouration Other Serious 1/27/2009 Female 185 lb 4/1/2009 Physician Ireland
Primary
Concomitant
Sputum Discoloured Hospitalization 4/19/2006 67 Male 180 lb 4/22/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Hypertension Required Intervention 4/3/2009 83 Male 5/12/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 11/1/2008 Female 6/5/2009 Consumer United States
Primary
Concomitant
Weight Decreased Death 68 Male 6/5/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Thyroid Disorder Death 1/1/2008 78 Female 7/1/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/14/2009 United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/17/2009 United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 11/1/2008 Female 7/23/2009 Consumer United States
Primary
Concomitant
Weight Decreased Death 68 Male 7/21/2009 United States
Primary
Concomitant
Visual Impairment Other Serious 52 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/3/2009 Female 8/5/2009 Physician United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Vomiting Death 56 Female 7/22/2009 United States
Primary
Concomitant
Weight Decreased Other Serious Female 7/31/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Visual Impairment Other Serious 52 Female 8/5/2009 Lawyer United States
Primary
Concomitant
Visceral Arterial Ischaemia Death 5/23/2009 Female 8/17/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Rectal Haemorrhage Other Serious 39 Female 8/9/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 39 Female 8/14/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 51 Male 8/20/2009 United States
Primary
Concomitant
Unemployment Other Serious 39 Female 8/21/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 8/27/2009 Pharmacist Canada
Primary
Concomitant
Weight Decreased Death 68 Male 8/25/2009 United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Vomiting Hospitalization 62 Female 8/25/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 190 lb 9/1/2009 Pharmacist Canada
Primary
Concomitant
Weight Decreased Hospitalization 62 Female 8/26/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/1/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 90 Female 9/2/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 80 Female 8/31/2009 United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/3/2009 United States
Primary
Concomitant
Surgery Hospitalization 90 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 9/15/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 9/16/2009 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 11/4/2008 68 Female 254 lb 11/12/2008 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 9/17/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 9/22/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 63 Male 180 lb 9/25/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 10/9/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 492 lb 10/16/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 10/16/2009 Lawyer United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 10/21/2009 United States
Primary
Concomitant
Weight Decreased Life Threatening 10/1/2007 Male 10/27/2009 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 56 Female 10/22/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 10/22/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 12/10/2006 83 Male 10/22/2009 Consumer United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/22/2009 Lawyer United States
Primary
Concomitant
Pain In Extremity Hospitalization 47 Male 10/27/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Other Serious 46 Female 223 lb 10/27/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 90 Female 10/26/2009 United States
Primary
Concomitant
Vomiting Hospitalization 56 Female 10/29/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/9/2009 United States
Primary
Concomitant
Vomiting Hospitalization 53 Female 11/4/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 90 Female 11/18/2009 United States
Primary
Concomitant
Vomiting Hospitalization 12/10/2006 83 Male 11/17/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 11/16/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/23/2007 54 Female 258 lb 11/18/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/25/2008 56 Male 11/20/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 68 Male 131 lb 12/2/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 12/1/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/1/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 1/25/2008 56 Male 12/11/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 53 Female 12/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 12/10/2009 United States
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 12/11/2009 United States
Primary
Concomitant
Neutropenic Sepsis Hospitalization 10/8/2009 Male 12/18/2009 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Other Serious 1/1/2009 Female 12/22/2009 Physician United States
Primary
Concomitant
Vascular Rupture Hospitalization 70 Female 1/7/2010 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 68 Male 131 lb 1/13/2010 United States
Primary
Concomitant
Multiple Injuries Death 85 Female 1/15/2010 United States
Primary
Concomitant
Pain Hospitalization Female 1/15/2010 United States
Primary
Concomitant
Vomiting Hospitalization 79 Male 1/21/2010 United States
Primary
Concomitant

Drug Data