Digoxin combined with Metoprolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Urine Output Decreased Hospitalization 10/1/2005 Female 1/4/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 9/14/2005 57 Female 211 lb 1/12/2006 United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2005 86 Female 170 lb 1/27/2006 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 32 Female 1/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Melaena Hospitalization 11/8/2005 65 Male 1/27/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 32 Female 1/30/2006 Physician France
Primary
Secondary
Concomitant
Vomiting Hospitalization 12/23/2005 91 Female 124 lb 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Hypoglycaemia Other Serious 89 Male 2/21/2006 Physician United States
Primary
Concomitant
Dysgeusia 10/1/2005 78 Male 200 lb 1/5/2006 Consumer United States
Primary
Concomitant
Toe Amputation Hospitalization 12/1/2001 53 Male 181 lb 2/22/2006 Lawyer United States
Primary
Concomitant
Insomnia 10/1/2005 83 Male 155 lb 1/5/2006 Consumer United States
Primary
Concomitant
Ventricular Dysfunction Other Serious 7/1/2002 65 Male 220 lb 2/23/2006 Physician United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 1/1/2006 91 Male 175 lb 3/3/2006 United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 10/12/2005 Female 2/28/2006 Physician United States
Primary
Secondary
Concomitant
Syncope Hospitalization 2/26/2006 Male 279 lb 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Urine Output Decreased Hospitalization 64 Male 3/7/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 64 Male 3/7/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 1/4/2005 82 Female 123 lb 3/2/2006 Other Health Professional Australia
Primary
Concomitant
Vascular Bypass Graft Other Serious 2/10/2006 67 Male 3/8/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Tract Infection Hospitalization 1/1/2005 73 Male 183 lb 5/1/2006 Physician United Kingdom
Primary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Toe Amputation Hospitalization 12/3/2001 53 Male 181 lb 5/11/2006 Lawyer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 4/1/2003 70 Female 170 lb 5/12/2006 Physician United States
Primary
Concomitant
Post-traumatic Stress Disorder Other Serious 1/1/2003 64 Female 154 lb 5/15/2006 Lawyer Canada
Primary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
Pericardial Effusion Hospitalization 4/1/2006 Male 5/31/2006 Consumer United States
Primary
Concomitant
Urinary Retention Other Serious 5/20/2006 82 Male 6/7/2006 Physician United States
Primary
Concomitant
Tremor Hospitalization 88 Female 175 lb 6/7/2006 United States
Primary
Secondary
Concomitant
Vertigo Hospitalization 88 Female 174 lb 6/8/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Vertigo Hospitalization 88 Female 174 lb 6/12/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Mental Status Changes Hospitalization 4/17/2006 Male 7/18/2006 Pharmacist United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 4/8/2006 Male 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 56 Male 190 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 7/1/2006 62 Female 8/1/2006 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 3/1/2006 57 Male 190 lb 8/2/2006 United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 1/1/2006 79 Female 88 lb 8/3/2006 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Traumatic Brain Injury Hospitalization 6/24/2006 85 Female 127 lb 8/10/2006 Pharmacist United States
Primary
Concomitant
Tachyarrhythmia Other Serious 6/1/2005 Female 9/22/2006 Physician Germany
Primary
Concomitant
Urosepsis Other Serious 1/1/2005 80 Female 9/29/2006 Consumer Canada
Primary
Concomitant
Nodal Arrhythmia Death 7/26/2006 86 Female 8/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 68 Female 110 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Pemphigoid Other Serious 70 Male 10/23/2006 United States
Primary
Concomitant
Erysipelas Hospitalization 5/1/2006 64 Female 10/24/2006 Consumer Sweden
Primary
Concomitant
Unresponsive To Stimuli Death 9/10/2006 60 Female 176 lb 11/3/2006 Physician Australia
Primary
Concomitant
Renal Failure Acute Hospitalization 10/21/2006 78 Male 11/3/2006 Physician United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 12/10/2005 75 Female 161 lb 11/1/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Death 12/26/2006 Female 147 lb 1/29/2007 United States
Primary
Concomitant
Osteonecrosis Other Serious 1/1/2006 79 Female 88 lb 2/5/2007 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 5/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 4/28/2007 77 Male 183 lb 6/5/2007 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Tract Infection Other Serious 10/1/2006 Male 167 lb 9/24/2007 Pharmacist United States
Primary
Concomitant
Vein Pain 88 Female 10/2/2007 Consumer United States
Primary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 78 Female 10/2/2007 Physician United States
Primary
Secondary
Weight Decreased Hospitalization 1/7/2007 74 Female 10/2/2007 Denmark
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/10/2007 71 Female 157 lb 10/15/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/10/2007 71 Female 154 lb 10/11/2007 United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/10/2007 71 Female 156 lb 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Tremor Other Serious 1/1/2007 63 Male 10/16/2007 Physician United States
Primary
Secondary
Concomitant
Multiple Drug Overdose Death 39 Male 10/12/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/24/2007 71 Female 156 lb 10/18/2007 Physician United States
Primary
Secondary
Concomitant
Fatigue Other Serious 9/10/2007 71 Female 156 lb 10/19/2007 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 9/24/2007 71 Female 157 lb 10/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/23/2002 Male 159 lb 10/17/2007 Physician United States
Primary
Concomitant
Visual Disturbance Other Serious 9/10/2007 71 Female 156 lb 10/22/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Thyroid Neoplasm Other Serious 1/1/2007 67 Male 10/23/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/10/2007 71 Female 157 lb 10/23/2007 United States
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/20/2007 54 Female 10/22/2007 Physician United States
Primary
Concomitant
Vision Blurred 84 Female 10/26/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 9/24/2007 71 Female 154 lb 10/25/2007 United States
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 9/10/2007 71 Female 156 lb 10/30/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Tract Infection Other Serious 1/1/2007 Female 11/21/2007 Consumer Canada
Primary
Concomitant
Sinus Congestion Other Serious 1/1/2005 Male 12/10/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Other Serious 5/15/2007 58 Female 12/17/2007 Physician United States
Primary
Concomitant
Rash 83 Female 120 lb 12/17/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 5/1/2007 93 Female 12/27/2007 Consumer United States
Primary
Concomitant
White Blood Cell Count Abnormal Hospitalization 12/27/2007 68 Female 163 lb 1/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Angiosarcoma Other Serious 12/1/2007 Male 196 lb 1/14/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 1/1/2005 76 Male 2/19/2008 Consumer Australia
Primary
Concomitant
Drug Administration Error Disability 1/29/2007 82 Male 2/27/2008 Physician United States
Primary
Secondary
Concomitant
Swelling Hospitalization 3/1/2008 74 Female 180 lb 5/27/2008 United States
Primary
Concomitant
Pain Hospitalization 4/1/2008 62 Male 325 lb 5/23/2008 United States
Primary
Concomitant
Eye Disorder Hospitalization 4/24/2008 61 Female 90 lb 5/29/2008 United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 4/21/2008 67 Male 179 lb 5/28/2008 United States
Primary
Concomitant
Unevaluable Event Death 2/29/2008 89 Female 126 lb 5/29/2008 United States
Primary
Concomitant
Oedema Peripheral Hospitalization 4/14/2008 70 Male 5/29/2008 United States
Primary
Concomitant
Death Death 4/22/2008 83 Male 5/29/2008 United States
Primary
Concomitant
Vomiting Death 3/23/2008 91 Female 160 lb 6/2/2008 United States
Primary
Concomitant
Haemorrhage Hospitalization 3/20/2008 48 Male 230 lb 6/2/2008 Consumer United States
Primary
Concomitant
Fall Other Serious 4/3/2008 57 Male 260 lb 5/30/2008 Consumer United States
Primary
Concomitant
Vomiting Hospitalization 6/26/2007 73 Female 135 lb 5/22/2008 United States
Primary
Concomitant
Muscular Weakness Hospitalization 2/13/2008 82 Female 115 lb 5/30/2008 United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2003 Female 120 lb 6/12/2008 Physician United States
Primary
Concomitant
Thrombosis Other Serious 5/1/2008 Male 166 lb 6/12/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 4/23/2008 69 Male 145 lb 5/30/2008 Consumer United States
Primary
Concomitant
Respiratory Rate Increased Required Intervention 75 Female 6/10/2008 Canada
Primary
Concomitant
Vomiting Other Serious 61 Male 6/13/2008 Consumer Canada
Primary
Concomitant
Cerebrovascular Accident Other Serious 5/14/2008 80 Female 6/13/2008 Consumer United States
Primary
Concomitant
Visual Disturbance Hospitalization 1/1/2004 Female 6/13/2008 France
Primary
Concomitant
Weight Decreased Hospitalization 3/28/2008 82 Male 6/5/2008 United States
Primary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/24/2007 80 Female 6/5/2008 United States
Primary
Concomitant
Tremor Hospitalization 10/1/2007 52 Male 180 lb 6/12/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/15/2008 61 Female 150 lb 6/9/2008 United States
Primary
Concomitant
Heart Rate Decreased Life Threatening 4/22/2008 Male 111 lb 4/24/2008 United States
Primary
Concomitant
Diarrhoea Hospitalization 3/10/2008 Male 170 lb 6/18/2008 Physician United States
Primary
Secondary
Concomitant
Nausea Death 4/12/2008 66 Male 6/13/2008 United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2008 75 Female 6/26/2008 Other Health Professional Canada
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 1/2/2008 Male 6/30/2008 United States
Primary
Concomitant
Tremor Death 2/2/2008 85 Male 120 lb 6/26/2008 Consumer United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 2/1/2008 71 Male 172 lb 7/1/2008 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 7/1/2008 78 Male 7/3/2008 Pharmacist United States
Primary
Secondary
Renal Failure Other Serious 11/1/2007 89 Female 100 lb 7/2/2008 United States
Primary
Concomitant
Myodesopsia Other Serious 5/1/2008 68 Male 7/17/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 3/1/2007 8/1/2008 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 1/1/2007 80 Female 150 lb 7/29/2008 Consumer United States
Primary
Concomitant
Scrotal Swelling Other Serious 11/1/2007 Male 8/15/2008 Consumer United States
Primary
Secondary
Concomitant
Dermatitis Contact 11/15/2007 Female 8/22/2008 Other Health Professional United States
Primary
Concomitant
Myoclonus Other Serious 8/19/2008 34 Male 112 lb 8/21/2008 Other Health Professional United States
Primary
Concomitant
Palpitations Hospitalization 73 Female 340 lb 9/8/2008 United States
Primary
Concomitant
Radiation Pneumonitis Hospitalization 8/9/2008 Male 215 lb 9/17/2008 Physician United States
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 71 Female 208 lb 9/12/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 5/4/2008 61 Male 9/12/2008 United States
Primary
Concomitant
Malaise Required Intervention 92 Male 160 lb 9/12/2008 Physician United States
Primary
Concomitant
Wheezing Hospitalization 1/1/2008 Female 244 lb 9/30/2008 Consumer United States
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/12/2008 Other Health Professional Denmark
Primary
Concomitant
Thrombosis Hospitalization 35 Female 11/20/2008 United States
Primary
Secondary
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/21/2008 Other Health Professional Denmark
Primary
Concomitant
Peripheral Coldness Other Serious 8/14/2008 Female 121 lb 11/21/2008 Pharmacist Canada
Primary
Concomitant
Fluid Retention Other Serious 7/1/2008 80 Male 190 lb 11/21/2008 Pharmacist United States
Primary
Concomitant
Rash 10/15/2008 Male 12/3/2008 Consumer
Primary
Concomitant
Hypersensitivity Death 80 Male 185 lb 11/25/2008 United States
Primary
Concomitant
Peripheral Coldness Other Serious 8/14/2008 Female 121 lb 12/10/2008 Pharmacist Canada
Primary
Concomitant
Thrombosis Hospitalization 35 Female 183 lb 12/11/2008 United States
Primary
Secondary
Liver Disorder Hospitalization 10/14/2008 81 Male 132 lb 12/12/2008 Other Health Professional Denmark
Primary
Concomitant
Rheumatoid Arthritis 10/21/2008 Female 130 lb 12/12/2008 Consumer United States
Primary
Concomitant
Urosepsis Hospitalization 3/24/2008 74 Male 190 lb 12/10/2008 United States
Primary
Concomitant
Radiation Pneumonitis Other Serious 8/9/2008 Male 215 lb 12/23/2008 Physician United States
Primary
Secondary
Concomitant
Visual Impairment Life Threatening 65 Male 238 lb 12/20/2008 Physician United States
Primary
Concomitant

Drug Data