Digoxin combined with Metolazone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Electromechanical Dissociation Life Threatening 9/12/2005 Male 9/23/2005 United States
Primary
Concomitant
Sepsis Life Threatening 12/27/2005 69 Male 200 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 6/17/2005 Female 160 lb 10/14/2005 Pharmacist United States
Primary
Secondary
Concomitant
Dysgeusia 10/1/2005 78 Male 200 lb 1/5/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Life Threatening 12/10/2005 73 Female 2/18/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 10/1/2000 79 Male 128 lb 3/2/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/24/2005 57 Male 3/3/2006 Other Health Professional United States
Primary
Concomitant
Pulmonary Oedema Other Serious 57 Female 3/1/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Renal Failure Acute Required Intervention 2/18/2006 75 Female 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 10/1/2000 79 Male 128 lb 4/3/2006 Physician United States
Primary
Concomitant
Pleural Effusion Hospitalization 3/17/2006 69 Male 177 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Renal Failure Hospitalization 10/1/2000 79 Male 128 lb 4/11/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 3/24/2003 63 Male 298 lb 5/11/2006 Physician United States
Primary
Concomitant
Pain In Extremity Other Serious 89 Male 142 lb 5/10/2006 United States
Primary
Concomitant
Decreased Appetite 1/1/2006 69 Male 177 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/22/2006 74 Male 225 lb 6/23/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/22/2006 74 Male 225 lb 6/23/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased Male 7/21/2006 Consumer United States
Primary
Concomitant
Tearfulness Required Intervention 77 Female 7/26/2006 Physician United States
Primary
Concomitant
Rash Other Serious 11/28/2005 47 Male 240 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Syncope 4/19/2006 87 Male 155 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Subdural Haematoma 4/19/2006 87 Male 155 lb 7/19/2006 Pharmacist United States
Primary
Concomitant
Therapy Non-responder Other Serious 1/1/2006 77 Female 8/14/2006 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 6/9/2006 64 Male 199 lb 6/9/2006 United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Plasmapheresis Hospitalization 9/13/2006 Female 10/4/2006 Physician United States
Primary
Concomitant
Nodal Arrhythmia Life Threatening 4/26/2006 Female 205 lb 10/5/2006 Pharmacist United States
Primary
Secondary
Concomitant
Plasmapheresis Hospitalization 9/1/2006 Female 132 lb 10/24/2006 Physician United States
Primary
Concomitant
Plasmapheresis Hospitalization 9/1/2006 Female 132 lb 11/7/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/1/2005 52 Male 11/13/2006 Consumer United States
Primary
Concomitant
Death Death 10/17/2006 71 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 12/6/2006 58 Male 182 lb 12/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Delusion Of Replacement Hospitalization 1/1/2006 77 Female 10/8/2006 Physician United States
Primary
Concomitant
Vomiting Other Serious 4/1/2006 71 Male 2/16/2007 Physician Singapore
Primary
Concomitant
Drug Toxicity Hospitalization 2/3/2007 53 Male 173 lb 2/12/2007 Pharmacist United States
Primary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 4/9/2006 66 Male 3/10/2007 Physician Canada
Primary
Secondary
Concomitant
Pollakiuria Other Serious 2/1/2007 Male 225 lb 3/14/2007 Consumer United States
Primary
Concomitant
Delusion Of Replacement Death 77 Female 3/23/2007
Primary
Secondary
Concomitant
Throat Irritation 11/12/2006 45 Female 281 lb 1/23/2007 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Vomiting Hospitalization 7/13/2006 72 Female 6/15/2007 Physician United Kingdom
Primary
Secondary
Vomiting Hospitalization 72 Female 6/20/2007 Consumer United Kingdom
Primary
Secondary
Tendon Injury Hospitalization 3/12/2007 60 Male 6/19/2007 Consumer United States
Primary
Concomitant
Vomiting Death 72 Female 6/20/2007 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 72 Female 6/19/2007 United Kingdom
Primary
Secondary
Vomiting Hospitalization 72 Female 6/19/2007 United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 72 Female 6/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Insulin Resistance Hospitalization 56 Male 7/23/2007 Consumer United States
Primary
Concomitant
Loss Of Consciousness Disability 4/14/2007 59 Male 243 lb 7/30/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/13/2006 72 Female 7/9/2007 United Kingdom
Primary
Secondary
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 8/31/2007 Physician Switzerland
Primary
Concomitant
Dyspnoea Hospitalization 7/10/2007 51 Female 10/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Sinusitis Disability 8/1/2007 66 Female 10/15/2007 Other Health Professional United States
Primary
Concomitant
Sinusitis Disability 8/1/2007 66 Female 11/12/2007 Other Health Professional United States
Primary
Concomitant
Pleural Effusion Hospitalization 11/7/2007 84 Male 11/29/2007 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 4/1/2007 59 Female 1/7/2008 Pharmacist United States
Primary
Secondary
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/21/2008 United States
Primary
Concomitant
Respiratory Failure Death Female 1/24/2008 Physician
Primary
Concomitant
Shock Haemorrhagic Life Threatening 1/15/2008 Female 247 lb 1/25/2008 United States
Primary
Concomitant
Respiratory Failure Death Female 1/30/2008 Physician
Primary
Concomitant
Sinusitis Disability 8/1/2007 66 Female 2/11/2008 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 1/1/2001 73 Male 3/5/2008 Physician United Kingdom
Primary
Concomitant
Hypotension Death Male 2/27/2008 United Kingdom
Primary
Concomitant
Oedema Peripheral 11/13/2007 Male 3/27/2008 Physician United States
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2006 Female 160 lb 4/14/2008 Physician United States
Primary
Concomitant
Renal Failure Hospitalization 10/10/2007 Female 250 lb 4/30/2008 Physician United States
Primary
Concomitant
Oral Intake Reduced Hospitalization Male 5/13/2008 United States
Primary
Concomitant
Respiratory Distress Hospitalization 4/29/2008 Male 260 lb 5/27/2008 Physician United States
Primary
Concomitant
Vomiting Hospitalization 4/1/2008 44 Female 5/22/2008 United States
Primary
Concomitant
Swelling Hospitalization 3/1/2008 74 Female 180 lb 5/27/2008 United States
Primary
Concomitant
Vomiting Death 3/17/2008 70 Male 5/28/2008 United States
Primary
Concomitant
Cardiac Failure Hospitalization 10/10/2007 Male 175 lb 6/4/2008 United States
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 6/13/2008 United States
Primary
Concomitant
Vomiting Hospitalization 5/15/2008 61 Female 150 lb 6/9/2008 United States
Primary
Concomitant
Visual Brightness Hospitalization 42 Male 275 lb 6/19/2008 United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 3/17/2008 77 Male 175 lb 4/30/2008 United States
Primary
Concomitant
Weight Decreased Other Serious 1/10/2007 60 Male 149 lb 6/23/2008 United States
Primary
Concomitant
Nausea Hospitalization 1/29/2008 99 Female 140 lb 6/17/2008 United States
Primary
Concomitant
Vomiting Hospitalization 12/1/2007 84 Male 150 lb 6/28/2008 United States
Primary
Concomitant
Respiratory Depression Death 4/1/2005 57 Female 7/7/2008 Pharmacist Canada
Primary
Concomitant
Vaginal Haemorrhage Life Threatening 1/15/2008 Female 247 lb 7/11/2008 United States
Primary
Concomitant
Pleural Effusion Hospitalization 6/25/2008 Male 170 lb 7/25/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 10/15/2007 60 Male 153 lb 7/24/2008 United States
Primary
Concomitant
Weight Decreased Required Intervention 3/4/2008 98 Female 129 lb 7/30/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/1/2008 77 Female 135 lb 8/1/2008 Physician United States
Primary
Concomitant
Weight Decreased Required Intervention 4/8/2008 98 Female 140 lb 8/20/2008 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 12/20/2007 79 Female 207 lb 8/22/2008 United States
Primary
Concomitant
Rash Macular 7/11/2008 Female 8/29/2008 United States
Primary
Concomitant
Throat Tightness Hospitalization 4/30/2007 79 Female 207 lb 10/10/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/15/2008 79 Female 156 lb 10/20/2008 United States
Primary
Concomitant
Death Death Female 133 lb 11/3/2008 United States
Primary
Concomitant
Visual Impairment Hospitalization 86 Female 10/29/2008 United States
Primary
Concomitant
Vomiting Life Threatening 12/1/2007 84 Male 150 lb 11/9/2008 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 2/15/2008 79 Female 156 lb 11/9/2008 Lawyer United States
Primary
Concomitant
Death Death Female 133 lb 11/21/2008 United States
Primary
Concomitant
Pruritus 7/31/2008 Male 11/26/2008 United States
Primary
Concomitant
Flushing Hospitalization 1/1/2006 Female 123 lb 1/28/2009 Physician United States
Primary
Concomitant
Product Quality Issue Other Serious 8/1/2008 83 Female 2/13/2009 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 3/1/2008 Female 184 lb 3/5/2009 Other Health Professional United States
Primary
Concomitant
Scab Hospitalization 66 Male 2/28/2009 United States
Primary
Concomitant
Multiple Injuries Death 67 Male 3/12/2009 United States
Primary
Concomitant
Xanthopsia Hospitalization 73 Female 166 lb 4/7/2009 United States
Primary
Concomitant
Renal Failure Hospitalization 66 Male 4/7/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 11/1/1995 Female 134 lb 4/27/2009 Lawyer United States
Primary
Secondary
Concomitant
Sputum Discoloured Hospitalization 4/19/2006 67 Male 180 lb 4/22/2009 United States
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/19/2006 67 Male 180 lb 5/1/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 66 Male 5/1/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 4/28/2008 65 Male 5/24/2009 United States
Primary
Concomitant
Respiratory Failure Death Female 158 lb 6/2/2009 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Death 71 Male 5/28/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 4/28/2008 65 Male 6/5/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 6/5/2009 Lawyer United States
Primary
Concomitant
Death Death 6/22/2009 Male 134 lb 6/29/2009 Consumer United States
Primary
Concomitant
Vertigo Hospitalization 4/28/2008 65 Male 7/1/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/11/2009 74 Male 7/7/2009 Pharmacist United States
Primary
Concomitant
Renal Disorder Hospitalization 4/28/2008 65 Male 7/7/2009 United States
Primary
Concomitant
Nausea 90 Male 7/14/2009 Consumer United States
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
Surgery Death 73 Female 7/13/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Fluid Retention Hospitalization 7/11/2009 Female 7/22/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2009 56 Female 258 lb 7/17/2009 United States
Primary
Concomitant
Multiple Injuries Hospitalization 70 Male 7/21/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 7/22/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 7/23/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 7/1/2007 48 Male 7/28/2009 Consumer United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 71 Female 7/22/2009 United States
Primary
Concomitant
Wound Hospitalization 71 Male 8/3/2009 United States
Primary
Concomitant
Vomiting Hospitalization 85 Female 8/3/2009 United States
Primary
Concomitant
Wheezing Death 52 Female 8/4/2009 Lawyer United States
Primary
Concomitant
Myocardial Infarction Hospitalization 47 Male 8/3/2009 Lawyer United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 60 Male 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 9/28/2005 71 Female 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 10/25/2007 73 Male 229 lb 8/4/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 78 Female 8/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 8/11/2009 United States
Primary
Concomitant

Drug Data