Digoxin combined with Metformin Hydrochloride

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Acute Hospitalization 3/20/2003 Female 1/4/2006 Australia
Primary
Concomitant
Syncope Other Serious 7/26/2005 Male 2/3/2006 Puerto Rico
Primary
Concomitant
Ventricular Asystole Death 7/15/2004 68 Female 128 lb 2/9/2006 Physician Brazil
Primary
Concomitant
Pleural Effusion Other Serious 7/26/2005 Male 215 lb 2/16/2006 Puerto Rico
Primary
Concomitant
Weight Decreased Hospitalization 3/1/2005 79 Male 216 lb 2/23/2006 Physician Italy
Primary
Concomitant
Psychotic Disorder Hospitalization 6/1/2005 59 Male 262 lb 2/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 2/12/2006 Female 205 lb 3/1/2006 Other Health Professional United States
Primary
Concomitant
Tachycardia Other Serious 2/12/2006 72 Female 161 lb 2/28/2006 Physician Germany
Primary
Concomitant
Psychotic Disorder Hospitalization 1/19/2006 59 Male 262 lb 3/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 2/12/2006 Female 205 lb 3/20/2006 Other Health Professional United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2005 Male 215 lb 4/7/2006 Puerto Rico
Primary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 3/25/2006 84 Female 5/3/2006 Consumer Italy
Primary
Secondary
Pneumonia Death 2/12/2006 70 Female 205 lb 6/13/2006 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
Rash Erythematous 1/1/2005 88 Female 110 lb 8/1/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Decreased 11/15/2005 74 Male 183 lb 8/1/2006 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Physician Canada
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 8/8/2006 Canada
Primary
Concomitant
Renal Impairment Hospitalization 74 Male 8/17/2006 Consumer France
Primary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 9/7/2006 Other Health Professional Japan
Primary
Concomitant
Renal Failure Acute Hospitalization 9/6/2004 Male 214 lb 9/7/2006 Australia
Primary
Concomitant
Malnutrition Hospitalization 1/1/2006 67 Male 132 lb 9/14/2006 Physician Canada
Primary
Concomitant
Drug Interaction 1/1/2005 69 Female 165 lb 9/14/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 10/10/2006 Other Health Professional Japan
Primary
Concomitant
Hypoglycaemia Other Serious 7/24/2006 77 Male 134 lb 12/21/2006 Physician Canada
Primary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 36 Female 117 lb 1/11/2007 Physician Ireland
Primary
Concomitant
Vomiting Hospitalization 1/1/2005 80 Female 4/5/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 3/4/2006 56 Female 120 lb 12/13/2006 Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/26/2007 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/1/2006 83 Male 11/20/2007 Other Health Professional Taiwan, Province Of China
Primary
Concomitant
Interacting
White Blood Cell Count Increased Other Serious 4/26/2006 Female 117 lb 12/28/2007 Physician Ireland
Primary
Concomitant
Blood Urea Increased Hospitalization 1/1/2007 46 Female 1/18/2008 Physician Malaysia
Primary
Concomitant
Medication Error Death 73 2/15/2008 Pharmacist United States
Primary
Secondary
Fatigue Other Serious 50 Female 268 lb 3/28/2008 Other Health Professional United States
Primary
Concomitant
Ventricular Fibrillation Death 8/24/2005 Male 5/13/2008 Czech Republic
Primary
Concomitant
Intra-abdominal Haematoma Hospitalization 4/28/2008 77 Male 231 lb 6/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Blood Glucose Increased Hospitalization 10/1/2006 93 Female 4/30/2008 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 97 Female 8/27/2008 Other Health Professional United Kingdom
Primary
Concomitant
Rash Hospitalization 9/5/2008 59 Female 10/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Other Serious 49 Female 190 lb 10/10/2008 Other Health Professional United States
Primary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/17/2008 Other Health Professional Japan
Primary
Secondary
Concomitant
Tooth Abscess Life Threatening 9/30/2008 72 Male 10/20/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Swollen Tongue Life Threatening 9/30/2008 72 Male 10/24/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 11/17/2006 72 Female 165 lb 10/27/2008 Physician Netherlands
Primary
Secondary
Concomitant
Product Quality Issue 3/18/2008 66 Male 10/30/2008 Consumer United States
Primary
Concomitant
Lipase Increased Other Serious 11/1/2008 83 Male 4/6/2009 Physician France
Primary
Concomitant
Vomiting Hospitalization 8/26/2008 61 Female 4/13/2009 Physician Spain
Primary
Secondary
Concomitant
Social Avoidant Behaviour Death Male 5/22/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Other Serious 76 Male 5/26/2009 Lawyer United States
Primary
Concomitant
Pain Death 68 Male 5/26/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 2/8/2007 Female 6/4/2009 Consumer
Primary
Concomitant
Drug Interaction Hospitalization 83 Male 6/5/2009 Taiwan, Province Of China
Primary
Concomitant
Interacting
Hypoglycaemic Unconsciousness Hospitalization 5/1/2009 Female 5/27/2009 Consumer United States
Primary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Sleep Disorder Hospitalization 5/1/2009 82 Male 6/4/2009 Physician United States
Primary
Secondary
Concomitant
Speech Disorder Hospitalization 3/14/2009 78 Female 6/5/2009 France
Primary
Secondary
Concomitant
Drug Toxicity Hospitalization 63 Female 6/11/2009 Netherlands
Primary
Secondary
Concomitant
Tinnitus Hospitalization 51 Male 7/21/2009 Lawyer United States
Primary
Secondary
Concomitant
Skin Burning Sensation 9/1/2008 Male 8/21/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 68 Male 183 lb 9/21/2009 United States
Primary
Concomitant
Respiratory Disorder Death 68 Male 9/18/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Secondary Adrenocortical Insufficiency Hospitalization 4/27/2009 83 Male 353 lb 9/30/2009 Physician United States
Primary
Concomitant
Throat Irritation Other Serious 9/16/2009 77 Male 170 lb 9/30/2009 Consumer United States
Primary
Concomitant
Ventricular Fibrillation Hospitalization 65 Male 9/22/2009 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 54 Male 281 lb 9/22/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 12/1/2008 52 Female 9/21/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 62 Male 267 lb 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 68 Female 9/25/2009 United States
Primary
Concomitant
Stress Hospitalization 61 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 7/1/2007 48 Male 456 lb 9/23/2009 United States
Primary
Concomitant
Ventricular Fibrillation Death 4/15/2008 60 Female 250 lb 9/24/2009 United States
Primary
Concomitant
Syncope Hospitalization 56 Female 260 lb 9/25/2009 United States
Primary
Concomitant
Vitamin D Deficiency Hospitalization 72 Female 9/23/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 56 Male 9/23/2009 United States
Primary
Concomitant
Tricuspid Valve Disease Hospitalization 6/5/2007 44 Male 213 lb 9/25/2009 United States
Primary
Concomitant
Sinus Rhythm Hospitalization 62 Female 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 46 Female 223 lb 9/25/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Unemployment Hospitalization 1/20/2006 73 Male 163 lb 9/22/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 50 Male 354 lb 9/22/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Pubis Fracture Hospitalization 9/27/2009 98 Female 110 lb 10/6/2009 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 4/1/2009 Female 280 lb 10/12/2009 Consumer United States
Primary
Concomitant
Petechiae Hospitalization 9/12/2009 76 Male 10/27/2009 Other Health Professional Italy
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Renal Failure Acute Hospitalization 12/19/2009 79 Female 163 lb 1/6/2010 Consumer United States
Primary
Secondary
Concomitant
Medication Error Male 1/6/2010 United States
Primary
Concomitant
Weight Decreased Hospitalization 64 Male 12/28/2009 United States
Primary
Concomitant
Palpitations 3/23/2009 79 Female 12/15/2009 Physician United States
Primary
Concomitant
Hypersensitivity Hospitalization 12/18/2009 79 Female 163 lb 1/15/2010 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Obstruction Hospitalization 76 Male 1/22/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 73 Female 2/19/2010 Consumer United Kingdom
Primary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 56 Female 260 lb 2/5/2010 United States
Primary
Concomitant
Wheezing Hospitalization 79 Male 2/5/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 59 Male 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 71 Female 2/5/2010 Lawyer United States
Primary
Concomitant
Ureteric Obstruction Hospitalization 3/14/2008 66 Male 2/5/2010 United States
Primary
Concomitant
Weight Increased Hospitalization Male 2/5/2010 Lawyer United States
Primary
Concomitant
Myocardial Infarction Other Serious 71 Female 2/5/2010 United States
Primary
Concomitant
Waist Circumference Increased Hospitalization 72 Male 256 lb 2/5/2010 United States
Primary
Concomitant
Pallor Hospitalization 2/6/2010 97 Male 2/26/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 73 Female 2/16/2010
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 10/13/2009 Female 3/2/2010 Physician Hungary
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 3/4/2010 Lawyer United States
Primary
Concomitant
Malaise Other Serious 2/19/2010 Female 3/1/2010 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 7/1/2008 Male 162 lb 3/8/2010 Physician United States
Primary
Concomitant
Subdural Haematoma Other Serious 87 Female 3/22/2010 Other Health Professional United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Male 179 lb 3/22/2010 Consumer United States
Primary
Concomitant
Nausea Hospitalization 3/14/2010 Female 149 lb 3/26/2010 Physician Australia
Primary
Secondary
Concomitant
Eosinophilic Cellulitis Hospitalization 6/1/2006 51 Male 4/29/2010 Other Health Professional France
Primary
Concomitant
Vomiting Other Serious 59 Female 4/27/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 4/28/2010 United States
Primary
Concomitant
Vomiting Life Threatening 4/5/2010 54 Male 192 lb 5/12/2010 Physician United States
Primary
Secondary
Concomitant
Loss Of Consciousness Other Serious 2/12/2010 60 Male 190 lb 5/19/2010 Other Health Professional Australia
Primary
Concomitant
Torsade De Pointes Life Threatening 64 Female 5/19/2010 Other Health Professional Canada
Primary
Secondary
Concomitant
Weight Increased Hospitalization 1/7/2007 49 Male 5/11/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 76 Male 5/18/2010 United States
Primary
Concomitant
Vomiting Other Serious 3/25/2010 54 Male 192 lb 5/27/2010 Physician United States
Primary
Secondary
Concomitant
Wheezing 74 Female 5/28/2010 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 11/1/2007 58 Male 137 lb 5/28/2010 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Paraesthesia 1/1/2009 65 Male 145 lb 6/29/2010 Pharmacist United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/28/2009 48 Female 7/16/2010 United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 5/22/2010 65 Female 7/30/2010 Other Health Professional Denmark
Primary
Concomitant
Urinary Retention Hospitalization 1/15/2010 74 Male 225 lb 9/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/17/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/20/2010 Physician United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 304 lb 9/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Tetany Other Serious 5/1/2010 46 Female 9/16/2010 United Kingdom
Primary
Concomitant
Prostatomegaly Other Serious 1/1/2010 73 Male 244 lb 10/29/2010 Consumer United States
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/29/2007 63 Male 262 lb 12/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Prostatomegaly Other Serious 1/1/2010 Male 244 lb 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Ventricular Arrhythmia Hospitalization 83 Female 12/15/2010 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Vasculitis Other Serious 10/29/2007 63 Male 262 lb 12/22/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 73 Female 12/13/2010 Spain
Primary
Secondary
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Thyroid Adenoma Hospitalization 9/2/2010 59 Male 400 lb 2/14/2011 Consumer United States
Primary
Concomitant
Cardiac Disorder Hospitalization 8/9/2010 68 Male 3/4/2011 Consumer Brazil
Primary
Secondary
Concomitant
Blood Creatine Phosphokinase Mb Increased Other Serious 4/1/2011 80 Male 4/19/2011 Physician China
Primary
Concomitant

Drug Data