Digoxin combined with Lactulose

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Vomiting Required Intervention 11/24/2005 25 Female 2/8/2006 Physician United States
Primary
Concomitant
Petechiae Hospitalization 1/16/2006 93 Female 88 lb 2/14/2006 Consumer France
Primary
Secondary
Concomitant
Vomiting 1/1/2005 53 Female 246 lb 1/25/2006 Other Health Professional United States
Primary
Concomitant
Delirium Other Serious 3/11/2006 93 Female 4/4/2006 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2004 54 Female 143 lb 4/10/2006 Physician United States
Primary
Secondary
Concomitant
Toe Amputation Death 52 Male 4/7/2006 Other Health Professional United States
Primary
Concomitant
Hyponatraemia Hospitalization 5/26/2005 63 Female 1/23/2006 Physician United States
Primary
Concomitant
Oral Candidiasis 1/1/2006 67 Female 135 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Vomiting 54 Female 230 lb 4/25/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 75 Female 7/5/2006 Other Health Professional France
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/14/2005 80 Male 8/1/2006 Pharmacist United States
Primary
Concomitant
Haemoptysis 71 Female 136 lb 7/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pain In Jaw 1/1/2005 53 Female 246 lb 7/25/2006 Other Health Professional United States
Primary
Concomitant
Respiratory Tract Infection Hospitalization 9/22/2005 65 183 lb 10/11/2006 Physician Ireland
Primary
Concomitant
Staphylococcal Infection Hospitalization 9/16/2005 65 183 lb 10/19/2006 Physician Ireland
Primary
Concomitant
Memory Impairment Other Serious 11/6/2006 81 Female 11/6/2006 Pharmacist United States
Primary
Concomitant
Neutropenia Required Intervention 9/6/2006 75 Male 144 lb 10/2/2006 Consumer United States
Primary
Concomitant
Paraesthesia Oral 71 Female 136 lb 10/24/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Splenomegaly Other Serious 58 Male 2/2/2007 Physician Turkey
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 87 Female 117 lb 3/6/2007 Physician Germany
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2004 72 Female 150 lb 3/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 10/1/2004 72 Female 150 lb 3/15/2007 Pharmacist United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2007 75 Male 137 lb 3/9/2007 Pharmacist United States
Primary
Concomitant
Toe Amputation Death 52 Male 3/14/2007 United States
Primary
Concomitant
Pain Hospitalization 2/15/2007 85 Female 99 lb 3/23/2007 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/1/2007 75 Male 137 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 11/10/2006 61 Female 130 lb 11/20/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 10/1/2006 87 Female 117 lb 4/12/2007 Other Health Professional Germany
Primary
Concomitant
Respiratory Arrest Death 10/1/2006 87 Female 117 lb 4/12/2007 Other Health Professional Germany
Primary
Concomitant
Rectal Haemorrhage Hospitalization 4/9/2007 87 Female 4/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Life Threatening 2/1/2007 63 Male 302 lb 4/30/2007 United Kingdom
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 5/30/2007 62 Female 7/17/2007 Other Health Professional France
Primary
Concomitant
Stenotrophomonas Sepsis Hospitalization 10/10/2006 57 Male 162 lb 1/15/2007 Pharmacist United States
Primary
Concomitant
Oesophageal Varices Haemorrhage Hospitalization 7/28/2007 85 Male 8/9/2007 Physician Guatemala
Primary
Concomitant
Myocardial Infarction Hospitalization 8/2/2007 50 Male 194 lb 8/15/2007 India
Primary
Secondary
Concomitant
General Physical Health Deterioration Hospitalization 78 Male 8/27/2007 Physician Belgium
Primary
Secondary
Concomitant
Fracture Other Serious 94 Female 9/28/2007 Physician United Kingdom
Primary
Concomitant
Vitreous Floaters 5/30/2007 88 Male 7/5/2007 Consumer United States
Primary
Concomitant
Myocardial Infarction Death 10/1/2006 87 Female 117 lb 11/30/2007 Consumer Germany
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Death 10/1/2006 87 Female 117 lb 12/21/2007 Consumer Germany
Primary
Concomitant
Lower Gastrointestinal Haemorrhage Hospitalization 7/25/2007 87 Female 192 lb 11/5/2007 Pharmacist United States
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 2/4/2008 Norway
Primary
Concomitant
Weight Decreased Hospitalization 11/28/2007 61 Female 2/8/2008 Sweden
Primary
Concomitant
Oesophagitis Haemorrhagic Hospitalization 1/3/2008 Male 2/21/2008 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Retention Required Intervention 1/3/2008 84 Male 2/21/2008 France
Primary
Concomitant
Renal Failure Hospitalization 1/1/2008 73 Female 112 lb 2/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 7/30/2007 78 Male 236 lb 3/6/2008 Physician United Kingdom
Primary
Concomitant
Jaundice Hospitalization 86 Male 3/7/2008 Pharmacist United Kingdom
Primary
Secondary
Abdominal Pain Upper 7/28/2006 Female 3/14/2008 Consumer United States
Primary
Concomitant
Jaundice Hospitalization 86 Male 3/7/2008 Pharmacist United Kingdom
Primary
Secondary
Pleural Effusion Hospitalization 3/15/2008 Female 203 lb 3/17/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Jaundice Hospitalization 86 Male 3/26/2008 Consumer United Kingdom
Primary
Secondary
Jaundice Hospitalization Male 3/27/2008 Physician United Kingdom
Primary
Secondary
Weight Decreased Hospitalization 11/28/2007 61 Female 3/28/2008 Sweden
Primary
Concomitant
Jaundice Hospitalization 86 Male 3/28/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/31/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/31/2008 Consumer United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/28/2008 Pharmacist United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 4/2/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/28/2008 Pharmacist United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 4/8/2008 United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 4/10/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 3/28/2008 United Kingdom
Primary
Secondary
Concomitant
Peritonitis Hospitalization 3/15/2008 71 Male 201 lb 4/10/2008 Physician United States
Primary
Concomitant
Swollen Tongue Hospitalization 4/5/2008 64 Female 146 lb 4/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/7/2008 Sweden
Primary
Concomitant
White Blood Cell Count Increased Other Serious 3/26/2008 83 Male 5/13/2008 Sweden
Primary
Concomitant
Jaundice Hospitalization 86 Male 5/12/2008 United Kingdom
Primary
Secondary
Jaundice Hospitalization Male 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization Male 6/4/2008 Physician United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization 86 Male 6/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Jaundice Hospitalization 86 Male 6/4/2008 Other Health Professional United Kingdom
Primary
Secondary
Upper Respiratory Tract Infection Other Serious 5/7/2008 62 Female 6/6/2008 Sweden
Primary
Concomitant
Jaundice Hospitalization 86 Male 6/10/2008 Other Health Professional Sweden
Primary
Secondary
Jaundice Hospitalization 6/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization 86 Male 6/11/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Jaundice Hospitalization 86 Male 6/16/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Jaundice Hospitalization 86 Male 6/12/2008 United Kingdom
Primary
Secondary
Concomitant
Nodal Arrhythmia Other Serious 10/22/2007 7/23/2008 Consumer United States
Primary
Concomitant
Carcinoma In Situ Of Skin Other Serious 4/4/2007 Female 137 lb 7/29/2008 Other Health Professional United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 73 Male 8/5/2008 Netherlands
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 5/1/2008 53 Female 8/8/2008 Physician United States
Primary
Concomitant
Jaundice Hospitalization 1/24/2008 86 Male 8/13/2008 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hyperthyroidism Hospitalization 5/21/2006 89 Female 99 lb 8/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Prothrombin Time Prolonged Other Serious 8/23/2008 89 Male 132 lb 9/16/2008 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 11/26/2007 65 Male 161 lb 10/12/2008 Physician Japan
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/12/2008 Other Health Professional Denmark
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/19/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 10/14/2008 81 Male 132 lb 11/21/2008 Other Health Professional Denmark
Primary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 10/21/2008 86 Female 11/18/2008 United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 10/21/2008 86 Female 11/25/2008 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/14/2008 81 Male 132 lb 12/12/2008 Other Health Professional Denmark
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 11/26/2007 65 Male 161 lb 12/11/2008 Physician Japan
Primary
Secondary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/16/2009 Other Health Professional United States
Primary
Concomitant
Left Ventricular Dysfunction Other Serious 2/1/2008 60 Male 269 lb 1/19/2009 Other Health Professional United States
Primary
Concomitant
Death Other Serious 70 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Rash Other Serious 9/19/2008 67 Male 1/21/2009 Physician United Kingdom
Primary
Concomitant
Jaundice 86 Male 5/8/2008 Other Health Professional United Kingdom
Primary
Secondary
Feeling Jittery 2/2/2009 Female 132 lb 2/4/2009 Physician United States
Primary
Concomitant
Purpura Hospitalization 3/17/2009 75 Male 3/27/2009 Physician France
Primary
Concomitant
Palpitations Hospitalization 4/1/2009 Female 148 lb 5/20/2009 Pharmacist United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 63 Male 6/17/2009 United States
Primary
Concomitant
Tic Other Serious 4/3/2008 61 Male 201 lb 6/19/2009 Physician United Kingdom
Primary
Concomitant
Renal Injury Life Threatening 6/3/2009 90 Male 7/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Social Problem Death 81 Female 7/14/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 63 Male 7/14/2009 United States
Primary
Concomitant
International Normalised Ratio Fluctuation 70 Male 201 lb 7/22/2009 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 63 Male 7/17/2009 United States
Primary
Concomitant
Social Avoidant Behaviour Death 80 Female 7/20/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 7/23/2009 United States
Primary
Concomitant
Tremor Hospitalization 79 Female 7/23/2009 United States
Primary
Concomitant
International Normalised Ratio Fluctuation 70 Male 201 lb 7/22/2009 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 8/5/2009 United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 8/11/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 67 Male 8/12/2009 Consumer United States
Primary
Concomitant
Urine Leukocyte Esterase Positive Hospitalization 79 Female 8/14/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 8/18/2009 United States
Primary
Concomitant
Tremor Other Serious 1/1/2009 Female 150 lb 8/25/2009 Consumer United States
Primary
Concomitant
Leukocytoclastic Vasculitis Hospitalization 3/16/2009 75 Male 287 lb 8/27/2009 Physician France
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 8/24/2009 United States
Primary
Concomitant
Weight Increased Other Serious 80 Female 9/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Tachycardia Hospitalization 63 Male 178 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 11/23/2007 66 Male 802 lb 9/3/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/14/2009 United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 9/7/2008 53 Male 243 lb 9/14/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 9/15/2009 United States
Primary
Concomitant
Surgery Hospitalization 78 Female 9/17/2009 United States
Primary
Concomitant
Varices Oesophageal Hospitalization 11/23/2007 64 Male 364 lb 9/18/2009 United States
Primary
Concomitant
Spinal Column Stenosis Hospitalization 9/7/2008 53 Male 9/28/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/10/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/7/2008 53 Male 243 lb 10/9/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 10/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/18/2009 United States
Primary
Concomitant
Surgery Hospitalization 78 Female 10/18/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 80 Female 10/22/2009 Lawyer United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/22/2009 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 66 Male 10/26/2009 Lawyer United States
Primary
Concomitant

Drug Data