Digoxin combined with Isosorbide Dinitrate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Liver Disorder Hospitalization 12/14/2004 72 Female 1/6/2006 Physician Japan
Primary
Concomitant
Drug Interaction Other Serious 1/17/2006 82 Male 1/31/2006 Pharmacist Japan
Primary
Concomitant
Interacting
Weight Decreased Hospitalization 10/27/2005 87 Male 127 lb 12/1/2005 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 64 Male 2/28/2006 Israel
Primary
Concomitant
Ventricular Tachycardia Other Serious 1/17/2006 Male 3/7/2006 Physician Japan
Primary
Concomitant
Interacting
Tricuspid Valve Incompetence Hospitalization 63 Male 3/16/2006
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 1/17/2006 Male 3/17/2006 Physician Japan
Primary
Concomitant
Interacting
Tricuspid Valve Incompetence Hospitalization 63 Male 3/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/15/2006 Pharmacist United States
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 3/21/2006 Physician Japan
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 63 Male 3/28/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 1/1/1999 77 Male 231 lb 4/4/2006 Lawyer United States
Primary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Syncope Hospitalization 3/1/2006 80 Male 6/5/2006 Other Health Professional
Primary
Secondary
Concomitant
Stomach Discomfort Hospitalization 1/1/2005 87 Male 134 lb 5/31/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 3/1/2006 80 Male 6/8/2006 Other Health Professional
Primary
Secondary
Concomitant
Septic Shock Other Serious 78 Male 6/2/2006 Other Health Professional Czech Republic
Primary
Concomitant
Vision Blurred Hospitalization 4/28/2006 59 Male 7/6/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypokalaemia Hospitalization 4/24/2006 55 Male Pharmacist United States
Primary
Concomitant
Medication Residue 75 Male 7/21/2006 Consumer United States
Primary
Concomitant
Nausea Death 92 Female 7/24/2006 Japan
Primary
Secondary
Concomitant
Electrocardiogram St Segment Depression Hospitalization 12/31/2005 84 Female 8/1/2006 Consumer Italy
Primary
Concomitant
White Blood Cell Count Increased Death 2/16/2006 70 Female 7/27/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased 6/1/2005 Male 215 lb 8/8/2006 Consumer United States
Primary
Concomitant
Medication Residue 64 Female 181 lb 8/14/2006 Consumer United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 11/14/1998 73 Male 8/15/2006 France
Primary
Concomitant
Cardiac Failure Congestive Other Serious 79 Male 8/8/2006 Other Health Professional Denmark
Primary
Concomitant
Rash Other Serious 11/28/2005 47 Male 240 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Death Death 8/26/2006 89 Female 9/5/2006 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Infusion Site Pain Other Serious 1/1/2005 64 Male 142 lb 9/15/2006 United States
Primary
Secondary
Concomitant
Laboratory Test Interference Other Serious 71 Female 115 lb 9/29/2006
Primary
Concomitant
Cardiac Failure Acute Hospitalization 8/11/2006 75 Female 133 lb 10/6/2006 Physician United States
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Other Serious 78 Male 10/6/2006 Physician Czech Republic
Primary
Secondary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 10/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Cardiac Murmur Hospitalization 4/24/2006 Female 160 lb 11/16/2006 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization Male 12/6/2006 Consumer Japan
Primary
Secondary
Concomitant
Sclerosing Encapsulating Peritonitis Other Serious 4/2/2005 56 Male 125 lb 11/21/2006 Physician Japan
Primary
Secondary
Concomitant
Cardiomegaly Other Serious 4/24/2006 Female 160 lb 12/14/2006 Consumer Canada
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 8/1/2006 79 Female 112 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Interacting
Splenomegaly Other Serious 58 Male 2/2/2007 Physician Turkey
Primary
Concomitant
Treatment Noncompliance Hospitalization 10/10/2006 Male 215 lb 12/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Protein Urine Required Intervention 70 Male 2/23/2006 United States
Primary
Concomitant
Syncope Hospitalization 1/1/2005 86 Male 160 lb 12/13/2006 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 8/1/2006 87 Male 120 lb 6/5/2007 Consumer United States
Primary
Concomitant
Cholelithiasis Hospitalization 2/22/2007 78 Female 122 lb 6/18/2007 United States
Primary
Concomitant
Hypoglycaemic Unconsciousness Other Serious 1/26/2007 82 Female 4/26/2007 United States
Primary
Secondary
Concomitant
Pain In Extremity 1/1/2007 55 Male 228 lb 6/7/2007 Consumer United States
Primary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Other Serious 7/1/2006 62 Male 163 lb 6/29/2007 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 12/1/2006 64 Male 7/16/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/13/2007 United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 8/1/2006 Female 7/26/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 54 Female 8/8/2007 Physician United States
Primary
Secondary
Concomitant
Pain 78 Female 8/3/2007 Consumer United States
Primary
Concomitant
Vomiting Other Serious 54 Female 8/16/2007
Primary
Secondary
Concomitant
Pulmonary Fibrosis Other Serious 7/28/2007 Male 9/6/2007 Other Health Professional Philippines
Primary
Concomitant
Pulmonary Hypertension Required Intervention 12/2/2006 50 Female 8/31/2007 Pharmacist United States
Primary
Secondary
Concomitant
Rash Other Serious 8/26/2007 10/17/2007 Physician United States
Primary
Secondary
Concomitant
Viral Infection 9/14/2006 66 Male 11/13/2007 Consumer United States
Primary
Concomitant
Weight Increased 83 Female 11/14/2007 Consumer United States
Primary
Concomitant
Drug Toxicity Hospitalization 10/12/2007 74 Male 95 lb 11/15/2007 Physician Korea, Republic Of
Primary
Secondary
Concomitant
Abdominal Pain 73 Male 11/16/2007 Consumer United States
Primary
Concomitant
Electrolyte Imbalance Life Threatening 11/29/2007 Other Health Professional Switzerland
Primary
Concomitant
Dyspnoea 67 Female 11/29/2007 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 10/12/2007 74 Male 95 lb 12/3/2007 Physician Korea, Republic Of
Primary
Concomitant
Renal Failure Hospitalization 8/1/2000 81 Male 185 lb 12/6/2007 Consumer United States
Primary
Concomitant
Sclerosing Encapsulating Peritonitis Death 2/1/2001 56 Male 123 lb 12/12/2007 Japan
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 12/17/2007 Physician United States
Primary
Concomitant
Malaise Hospitalization 9/8/2007 75 Female 12/17/2007 United Kingdom
Primary
Concomitant
Hypertension Other Serious Female 1/1/2008 Consumer United States
Primary
Concomitant
Pyrexia Hospitalization 10/12/2007 74 Male 95 lb 1/14/2008 Physician Korea, Republic Of
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 1/18/2008 United States
Primary
Concomitant
Splenomegaly Other Serious 6/1/2007 Female 144 lb 1/24/2008 Physician United States
Primary
Secondary
Concomitant
Eosinophilia Death 1/24/2008 United States
Primary
Concomitant
Xanthopsia Other Serious 62 Male 1/28/2008 Physician Japan
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 2/4/2008 United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/21/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 1/30/2008 Other Health Professional United Kingdom
Primary
Concomitant
Ascites Other Serious 63 Female 180 lb 2/22/2008 United States
Primary
Concomitant
Pain In Extremity Other Serious 11/1/2007 Female 160 lb 2/22/2008 Canada
Primary
Concomitant
Tachycardia Hospitalization 1/8/2008 Male 2/27/2008 Other Health Professional United States
Primary
Concomitant
Dyspnoea 67 Female 3/6/2008 Consumer United States
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2007 Male 3/3/2008 Physician United States
Primary
Concomitant
Rash 8/22/2007 84 Male 180 lb 2/15/2008 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 6/29/2007 Male 3/13/2008 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint 2/6/2008 87 Female 3/13/2008 Consumer United States
Primary
Concomitant
Syncope Vasovagal Hospitalization 9/8/2007 75 Female 3/7/2008 United Kingdom
Primary
Concomitant
Generalised Oedema Hospitalization 12/19/2007 81 Female 112 lb 3/11/2008 Other Health Professional Japan
Primary
Concomitant
Ascites Other Serious 9/1/2007 63 Female 233 lb 3/20/2008 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 1/1/2007 64 Male 3/17/2008 United Kingdom
Primary
Concomitant
Vomiting Other Serious 54 Female 3/26/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 3/28/2008 United Kingdom
Primary
Concomitant
Vomiting Hospitalization 4/9/2007 85 Female 150 lb 3/7/2008 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 70 Male 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Death 9/13/2004 77 Female 220 lb 4/18/2008 United Kingdom
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 4/21/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Death Death 5/10/1998 Female 155 lb 4/22/2008 Physician United States
Primary
Concomitant
Occult Blood Positive Hospitalization 1/1/2008 Male 4/24/2008 Physician United States
Primary
Concomitant
Ischaemia Other Serious 4/24/2008 Female 153 lb 4/30/2008 Other Health Professional United States
Primary
Concomitant
Wheezing Other Serious 5/7/2008 84 Female 5/14/2008 Consumer United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Febrile Neutropenia Hospitalization 4/1/2008 Male 5/16/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 5/23/2008 Physician United States
Primary
Secondary
Concomitant
Chest Pain Hospitalization 1/13/2008 55 Male 174 lb 5/21/2008 United States
Primary
Concomitant
Joint Effusion Death 6/30/2007 84 Male 185 lb 5/23/2008 United States
Primary
Concomitant
Loss Of Consciousness Other Serious 4/1/2008 79 Male 180 lb 5/28/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 3/20/2008 67 Male 165 lb 5/29/2008 United States
Primary
Concomitant
Vomiting Death 4/2/2008 55 Male 170 lb 6/3/2008 United States
Primary
Concomitant
Urethritis Hospitalization 1/30/2008 63 Male 6/5/2008 Norway
Primary
Concomitant
Vomiting Hospitalization 1/1/2007 Female 159 lb 6/16/2008 Physician United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Hospitalization 12/24/2007 80 Female 6/5/2008 United States
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
White Blood Cell Count Decreased Required Intervention 4/1/2008 73 Female 148 lb 6/10/2008 Physician United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 11/24/2007 76 Female 137 lb 6/17/2008 United States
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Pain In Extremity Other Serious 6/1/2008 Female 160 lb 6/27/2008 Canada
Primary
Concomitant
Weight Decreased Other Serious 75 Male 205 lb 6/12/2008 United States
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 59 Female 150 lb 6/27/2008 United States
Primary
Concomitant
Atrial Fibrillation Other Serious 5/28/2008 63 Male 7/16/2008 Consumer United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 65 Male 185 lb 7/18/2008 Consumer United States
Primary
Concomitant
Angina Pectoris Hospitalization 6/4/2008 Female 8/13/2008 Other Health Professional United States
Primary
Concomitant
Hernia Hospitalization 8/6/2008 58 Male 152 lb 8/18/2008 Other Health Professional China
Primary
Concomitant
Orthostatic Hypotension Other Serious 9/1/2006 80 Female 8/14/2008 Physician Canada
Primary
Secondary
Concomitant
Glomerular Filtration Rate Decreased Other Serious 80 Female 8/19/2008 Canada
Primary
Secondary
Concomitant
Fall Hospitalization 1/1/2006 Female 8/21/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Hydrocele Hospitalization 7/1/2008 58 Male 152 lb 8/28/2008 Other Health Professional China
Primary
Concomitant
Heart Rate Decreased Other Serious 80 Female 8/26/2008 Pharmacist Denmark
Primary
Concomitant
Metabolic Disorder Hospitalization 80 Female 8/21/2008 Consumer Canada
Primary
Secondary
Concomitant
Fall Hospitalization 80 Female 11/11/2008 Canada
Primary
Secondary
Concomitant
Pain In Extremity Other Serious 6/1/2008 Female 160 lb 11/20/2008 Canada
Primary
Concomitant
Hepatic Function Abnormal Other Serious 4/25/2007 77 Female 11/24/2008 Physician Japan
Primary
Concomitant
Fall Other Serious 9/1/2006 80 Female 12/1/2008
Primary
Secondary
Fall Hospitalization 1/1/2006 80 Female 11/26/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Rib Fracture Hospitalization 11/1/2007 68 Male 178 lb 12/10/2008 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2008 80 Female 215 lb 11/19/2008 Pharmacist United States
Primary
Concomitant
Ventricular Extrasystoles Other Serious 4/1/1999 Male 12/18/2008 Pharmacist Japan
Primary
Concomitant
Vomiting Other Serious 2/9/2008 Male 1/19/2009 Lawyer United States
Primary
Concomitant
Memory Impairment Other Serious 1/1/1997 Female 200 lb 1/15/2009 Consumer United States
Primary
Concomitant
No Therapeutic Response Hospitalization 80 Female 1/20/2009 Canada
Primary
Concomitant

Drug Data