Digoxin combined with Hydrochlorothiazide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Transient Ischaemic Attack Other Serious 77 Female 150 lb 1/5/2006 United States
Primary
Concomitant
Erectile Dysfunction 5/1/2005 74 Male 12/28/2005 United States
Primary
Concomitant
Paradoxical Drug Reaction 10/11/2005 81 Female 150 lb 1/5/2006 Consumer United States
Primary
Concomitant
Myocardial Infarction Other Serious 2/8/2006 42 Male 2/24/2006 Physician China
Primary
Concomitant
Ventricular Hypertrophy Other Serious 79 Male 180 lb 2/22/2006 Physician United States
Primary
Secondary
Concomitant
Ventricular Fibrillation Life Threatening 12/14/2005 73 Female 3/2/2006 Germany
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 1/1/2006 63 Female 135 lb 3/3/2006 United States
Primary
Secondary
Concomitant
Syncope Hospitalization 12/8/2004 48 Male 269 lb 11/21/2005 Physician United States
Primary
Secondary
Concomitant
Gastric Ulcer Haemorrhage Hospitalization 10/1/2003 75 Female 94 lb 3/27/2006 Physician Hungary
Primary
Secondary
Concomitant
Throat Irritation Death 2/20/2006 72 Male 228 lb 3/24/2006 Pharmacist United States
Primary
Concomitant
Oedema 6/21/2005 50 Female 252 lb 1/25/2006 Pharmacist United States
Primary
Concomitant
Pancytopenia Hospitalization 1/3/2006 65 Male 258 lb 4/11/2006 Consumer United States
Primary
Secondary
Concomitant
Asthenia Hospitalization 1/19/2005 76 Male 199 lb 2/14/2006 Physician United States
Primary
Concomitant
Depression Hospitalization 5/1/2001 60 Female 150 lb 4/24/2006 Lawyer United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2006 63 Female 135 lb 4/21/2006 Physician United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 3/25/2006 75 Female 170 lb 5/1/2006 Pharmacist United States
Primary
Concomitant
Unevaluable Event Other Serious 1/1/2006 63 Female 135 lb 5/8/2006 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Death 2/20/2006 72 Male 228 lb 5/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased 49 Female 3/17/2006 Other Health Professional United States
Primary
Concomitant
Drug Ineffective 1/1/2006 77 Male 5/5/2006 Consumer United States
Primary
Concomitant
Hypoaesthesia Facial 50 Female 247 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 1/27/2006 68 Female 265 lb 6/26/2006 Physician Canada
Primary
Concomitant
Troponin I Increased Other Serious 58 Female 119 lb 6/30/2006 United States
Primary
Secondary
Concomitant
Tenderness Hospitalization 6/3/2006 92 Female 112 lb 6/27/2006 Physician United States
Primary
Concomitant
Diverticulum Intestinal Haemorrhagic Hospitalization 5/1/2006 92 Female 112 lb 6/30/2006 Consumer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 58 Female 119 lb 7/18/2006 Canada
Primary
Concomitant
Skin Exfoliation 7/1/2005 75 Female 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Musculoskeletal Pain Other Serious 2/27/2006 72 Female 148 lb 7/24/2006 Consumer United States
Primary
Concomitant
Non-small Cell Lung Cancer Hospitalization 3/11/2005 65 Male 7/24/2006 Physician Russian Federation
Primary
Concomitant
Osteoporotic Fracture Hospitalization 3/1/2006 Male 7/28/2006 Consumer United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 6/7/2006 63 Female 181 lb 7/24/2006 Consumer United States
Primary
Secondary
Concomitant
Nervousness 2/1/2006 84 Female 108 lb 7/12/2006 Consumer United States
Primary
Concomitant
Vomiting 76 Female 7/19/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 7/3/2006 69 Female 193 lb 9/14/2006 Other Health Professional United States
Primary
Secondary
Stomatitis Other Serious 3/1/2006 76 Female 9/25/2006 United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 10/16/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Disability 8/1/2006 71 Female 115 lb 10/24/2006 Physician United States
Primary
Concomitant
Vomiting Required Intervention 8/27/2005 43 Female 10/18/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/26/2006 86 Male 10/30/2006 Pharmacist Canada
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 10/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 9/15/2006 71 Male 11/10/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Life Threatening 5/19/2006 62 Female 11/8/2006 Pharmacist United States
Primary
Concomitant
Chest Pain Hospitalization 11/9/2006 50 Male 11/17/2006 United States
Primary
Concomitant
Haemorrhage Other Serious 11/10/2006 86 Female 11/17/2006 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 11/4/2006 39 Female 121 lb 11/20/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 9/15/2006 71 Male 12/5/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 11/1/2006 50 Male 12/7/2006 United States
Primary
Concomitant
Speech Disorder Other Serious 11/2/2006 89 Female 113 lb 11/30/2006 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Haemorrhoidal Haemorrhage 11/10/2006 86 Female 12/18/2006 Consumer United States
Primary
Concomitant
Weight Decreased Life Threatening 9/3/2006 59 Female 132 lb 10/26/2006 Pharmacist United States
Primary
Secondary
Concomitant
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Mental Impairment 8/19/2006 55 Female 197 lb 10/24/2006 United States
Primary
Concomitant
Osteonecrosis Other Serious 5/1/2005 63 Female 157 lb 11/28/2006 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 1/10/2007 85 Female 142 lb 1/23/2007 Consumer United States
Primary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 1/30/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 10/31/2006 78 Male 2/8/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/13/2007 Physician United States
Primary
Concomitant
Swollen Tongue Other Serious 1/20/2007 60 Male 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Wheezing Life Threatening 1/17/2007 1 Male 15 lb 2/23/2007 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Female 3/15/2007 Consumer United States
Primary
Concomitant
Death Death 2/25/2007 60 Male 3/19/2007 Physician United States
Primary
Concomitant
Rash Pruritic Other Serious 1/12/2007 85 Female 142 lb 3/22/2007 Consumer United States
Primary
Concomitant
Nausea Other Serious 8/1/2006 64 Female 216 lb 11/28/2006 United States
Primary
Concomitant
Pain In Jaw 9/8/2006 40 Female 150 lb 1/23/2007 Consumer United States
Primary
Concomitant
Polyp 12/11/2006 80 Male 225 lb 4/30/2007 Consumer United States
Primary
Concomitant
Ulcer Other Serious 8/15/2006 Female 151 lb 5/3/2007 Consumer Canada
Primary
Concomitant
Vomiting Hospitalization 65 Female 5/14/2007
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 65 Female 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Xanthopsia Hospitalization 65 Female 5/11/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 74 Male 5/23/2007 Consumer United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/5/2006 79 Male 5/23/2007 Physician United States
Primary
Concomitant
Vomiting Hospitalization 65 Female 5/17/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 65 Female 5/25/2007 Physician United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 65 Female 6/1/2007 Physician Australia
Primary
Concomitant
Interacting
Pulmonary Hypertension Other Serious 6/1/2002 63 Male 269 lb 6/12/2007 Consumer United States
Primary
Concomitant
Ulcer Other Serious 4/1/2006 Female 151 lb 6/12/2007 Consumer Canada
Primary
Concomitant
Unevaluable Event Hospitalization 58 Female 119 lb 6/8/2007 Other Health Professional Canada
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 6/8/2007 Physician United States
Primary
Secondary
Xanthopsia Hospitalization 65 Female 6/18/2007 Physician United States
Primary
Concomitant
Cholelithiasis Hospitalization 2/22/2007 78 Female 122 lb 6/18/2007 United States
Primary
Concomitant
Visual Disturbance Other Serious 8/1/2000 Male 225 lb 6/28/2007
Primary
Concomitant
Vertigo Hospitalization 6/21/2007 74 Male 186 lb 7/11/2007 Physician United States
Primary
Secondary
Concomitant
Stomatitis Other Serious 3/1/2006 76 Female 7/13/2007 United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/13/2007 United States
Primary
Concomitant
Vomiting Hospitalization 2/22/2007 78 Female 122 lb 7/12/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Distress Hospitalization 3/1/2007 78 Male 7/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious 7/1/2007 80 Male 200 lb 7/26/2007 Consumer United States
Primary
Concomitant
Foot Operation Other Serious Female 151 lb 8/15/2007 Canada
Primary
Concomitant
Ventricular Arrhythmia Hospitalization 8/12/2007 67 Male 8/16/2007 Pharmacist United States
Primary
Secondary
Tachycardia Hospitalization 78 Female 8/17/2007 Greece
Primary
Secondary
Application Site Pruritus 1/26/2007 82 Female 8/27/2007 Consumer United States
Primary
Concomitant
Nephritis Interstitial Life Threatening 1/1/2007 79 Female 113 lb 9/4/2007 Physician United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 9/13/2007 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 8/1/2006 Male 209 lb 9/18/2007 United States
Primary
Secondary
Nausea 1/11/2007 69 Female 8/16/2007 Physician United States
Primary
Concomitant
Ventricular Extrasystoles Hospitalization 5/1/2007 79 Female 9/26/2007 China
Primary
Concomitant
Atrioventricular Block 4/17/1985 86 Female 10/9/2007 United States
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 10/9/2007 Male 165 lb 10/12/2007 United States
Primary
Secondary
Concomitant
Dysphonia 65 Female 10/24/2007 Consumer United States
Primary
Concomitant
Contusion Other Serious 9/26/2007 Female 151 lb 11/7/2007 Canada
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/7/2007 76 Male 288 lb 3/23/2007 Pharmacist United States
Primary
Concomitant
Myalgia 9/1/2007 Female 170 lb 11/12/2007 Consumer United States
Primary
Concomitant
Oedema Peripheral 12/1/2006 86 Male 11/14/2007 Consumer United States
Primary
Concomitant
Mood Swings Male 11/14/2007 Consumer United States
Primary
Concomitant
Visual Disturbance 3/1/2006 75 Male 11/14/2007 Consumer United States
Primary
Concomitant
Abdominal Pain 73 Male 11/16/2007 Consumer United States
Primary
Concomitant
Contusion Other Serious 2/1/2007 Female 151 lb 11/19/2007 Canada
Primary
Concomitant
Haemoconcentration Other Serious 8/16/2007 60 Male 11/16/2007 Russian Federation
Primary
Secondary
Dyspnoea Hospitalization 11/9/2007 62 Male 154 lb 12/19/2007 Consumer Brazil
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 9/1/2006 Male 12/19/2007 Physician United States
Primary
Concomitant
Dyspnoea Hospitalization 11/9/2007 62 Male 154 lb 12/20/2007 Consumer Brazil
Primary
Concomitant
Drug Ineffective 11/1/2006 80 Male 12/21/2007 Consumer United States
Primary
Concomitant
Osteonecrosis Other Serious 6/29/2005 60 Female 11/28/2007 Physician United States
Primary
Concomitant
Serum Ferritin Increased Other Serious 12/1/2006 79 Male 187 lb 1/16/2008 Physician United States
Primary
Concomitant
Atrioventricular Block Other Serious 4/17/1985 86 Female 12/12/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Constipation 11/15/2007 Female 1/17/2008 Consumer United States
Primary
Concomitant
Constipation 11/15/2007 Female 1/31/2008 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 79 Female 2/1/2008 Physician Canada
Primary
Concomitant
Panic Attack Other Serious 1/1/2007 2/12/2008 Consumer Portugal
Primary
Secondary
Concomitant
Rash Erythematous Other Serious 67 Female 2/13/2008 Italy
Primary
Secondary
Concomitant
Muscle Spasms 11/9/2007 77 Female 131 lb 11/9/2007 Other Health Professional United States
Primary
Concomitant
Constipation 11/15/2007 Female 2/26/2008 Consumer United States
Primary
Concomitant
Orthopedic Procedure Other Serious 1/1/2007 Female 111 lb 2/27/2008 Physician United States
Primary
Concomitant
Post Procedural Complication Hospitalization 1/28/2008 86 Female 189 lb 2/22/2008 Other Health Professional United States
Primary
Concomitant
Pneumonia Hospitalization 11/1/2007 79 Female 3/13/2008 Physician Canada
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 1/1/2007 76 Male 3/14/2008 Physician United States
Primary
Concomitant
Psoriasis Other Serious 67 Female 3/13/2008 Other Health Professional United States
Primary
Concomitant
Dermatitis Contact 11/15/2007 Female 4/9/2008 Other Health Professional United States
Primary
Concomitant
Vascular Pseudoaneurysm Other Serious 3/23/2008 84 Female 123 lb 4/15/2008 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 12/7/2007 82 Female 139 lb 3/31/2008 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 12/7/2006 64 Male 4/18/2008 Malaysia
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 4/28/2008 91 Male 5/5/2008 Pharmacist United States
Primary
Concomitant
Chromaturia Other Serious 4/1/2008 Male 5/13/2008 Consumer Canada
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 5/13/2008 67 Female 210 lb 5/15/2008 Consumer United States
Primary
Concomitant
Pacemaker Complication Death 1/31/2008 54 Male 250 lb 5/16/2008 United States
Primary
Concomitant
Weight Increased 1/1/2001 Male 163 lb 5/30/2008 Consumer United States
Primary
Concomitant
Loss Of Consciousness Hospitalization 4/1/2008 75 Female 5/22/2008 United States
Primary
Concomitant
Pulse Absent Death 1/4/2008 87 Male 5/23/2008 United States
Primary
Concomitant
Head Injury Other Serious 12/25/2007 87 Female 145 lb 5/23/2008 United States
Primary
Concomitant
Haemorrhage Hospitalization 4/1/2008 77 Female 163 lb 5/23/2008 United States
Primary
Concomitant
Pruritus Generalised Disability 1/1/2007 85 Male 6/11/2008 Consumer United States
Primary
Concomitant
Weight Decreased 5/23/2006 76 Female 170 lb 4/10/2008 Consumer United States
Primary
Concomitant
Hot Flush Other Serious 6/18/2008 83 Male 161 lb 6/26/2008 Pharmacist United States
Primary
Concomitant
Dyspnoea Other Serious 3/1/2008 72 Female 125 lb 6/13/2008 United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/6/2008 86 Female 135 lb 6/19/2008 Consumer United States
Primary
Concomitant
Nausea Hospitalization 1/29/2008 99 Female 140 lb 6/17/2008 United States
Primary
Concomitant
Myalgia Other Serious 12/10/2007 72 Female 227 lb 6/23/2008 Physician United States
Primary
Concomitant
Ventricular Hypokinesia Hospitalization 8/7/2006 Male 209 lb 7/8/2008 United States
Primary
Secondary

Drug Data