Digoxin combined with Heparin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Renal Impairment Hospitalization 10/16/2005 85 Male 137 lb 12/29/2005 Pharmacist United States
Primary
Concomitant
Malaise Other Serious 1/1/2003 70 Male 2/8/2006 United States
Primary
Concomitant
Urticaria Death 70 Male 2/13/2006 Canada
Primary
Concomitant
Convulsion Other Serious 13 Male 2/28/2006 Consumer United States
Primary
Concomitant
Ventricular Hypertrophy Other Serious 7/3/2005 Female 195 lb 3/3/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 57 Female 3/17/2006 United States
Primary
Secondary
Concomitant
Pulmonary Oedema Required Intervention 57 Female 3/30/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Urticaria Death 1/9/2004 71 Male 4/26/2006 Canada
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 5/18/2006 United States
Primary
Secondary
Concomitant
Staphylococcal Infection Other Serious 1/1/2006 63 Male 121 lb 5/18/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Required Intervention 3/13/2006 76 Male 198 lb 5/11/2006 Physician United States
Primary
Secondary
Concomitant
Agranulocytosis Other Serious 5/10/2006 81 Female 132 lb 6/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Paralysis Hospitalization 3/13/2006 90 Female 7/2/2006 Denmark
Primary
Secondary
Concomitant
Wound Secretion Other Serious 8/1/2004 74 Female 114 lb 6/29/2006 United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 114 lb 7/18/2006 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 11/1/2003 67 Female 113 lb 7/18/2005 Pharmacist United States
Primary
Secondary
Concomitant
Premature Baby Congenital Anomaly 8/1/2006 Consumer Germany
Primary
Secondary
Mental Status Changes Hospitalization 11/21/2005 83 Male 170 lb 8/15/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/27/2006 77 Male 110 lb 8/16/2006 Argentina
Primary
Secondary
Concomitant
Skin Discolouration Hospitalization 7/13/2006 48 Male 128 lb 8/23/2006 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 7/27/2006 77 Male 110 lb 8/29/2006 Argentina
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization 7/27/2006 77 Male 110 lb 9/6/2006 Argentina
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious Male 9/15/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Tachycardia Other Serious Male 9/19/2006 Other Health Professional United States
Primary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/29/2006 Female 165 lb 10/23/2006 Physician Poland
Primary
Secondary
Concomitant
Bronchospasm Life Threatening 4/26/2006 37 Female 10/27/2006 Consumer Japan
Primary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 74 Female 115 lb 10/30/2006 Physician United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 7/20/2006 69 Male 11/1/2006 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Ventricular Hypokinesia Other Serious 8/1/2004 Female 11/9/2006 Consumer Germany
Primary
Secondary
Concomitant
Haematoma Hospitalization 9/17/2006 76 Female 97 lb 11/7/2006 Pharmacist United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Other Serious 8/29/2006 Female 165 lb 11/28/2006 Physician Poland
Primary
Secondary
Concomitant
Heparin-induced Thrombocytopenia Other Serious 7/29/2006 70 Male 215 lb 9/18/2006 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Hospitalization 12/26/2003 65 Female 11/29/2006 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 10/5/2006 65 Female 110 lb 12/18/2006 Physician Japan
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 12/17/2006 66 Male 210 lb 1/8/2007 Pharmacist United States
Primary
Concomitant
Subdural Haematoma Life Threatening 2/19/2007 85 Female 2/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
Retroperitoneal Haemorrhage Required Intervention 10/20/2006 81 Female 168 lb 10/24/2006 United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 7/7/2006 73 Female 3/19/2007 Other Health Professional South Africa
Primary
Concomitant
Urticaria 9/1/2006 28 Female 200 lb 1/23/2007 Pharmacist United States
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Rash Other Serious 4/24/2007 80 Male 198 lb 4/25/2007 Physician United States
Primary
Concomitant
Haemorrhage Other Serious 3/15/2007 67 Male 218 lb 5/10/2007 Other Health Professional United States
Primary
Concomitant
Spinal Cord Ischaemia Hospitalization 1/10/2007 77 Female 157 lb 4/26/2007 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 71 Female 6/26/2007 Physician Belgium
Primary
Secondary
Concomitant
Skin Burning Sensation Hospitalization 3/16/2007 53 Female 126 lb 6/27/2007 Pharmacist United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/17/2007 68 Female 185 lb 7/25/2007 United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Life Threatening 2/6/2007 60 Male 7/25/2007 Physician Japan
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 6/26/2007 81 Female 141 lb 7/25/2007 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 7/24/2007 68 Female 116 lb 8/3/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 2/11/2004 52 Male 7/31/2007 Canada
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 4/26/2006 71 Female 8/8/2007 Pharmacist United States
Primary
Concomitant
Wound Secretion Life Threatening 6/18/2007 88 Pharmacist United States
Primary
Concomitant
Transplant Rejection Other Serious 54 Female 8/30/2007 United States
Primary
Concomitant
Transplant Rejection Other Serious 54 Female 9/4/2007 United States
Primary
Concomitant
Pyelonephritis Hospitalization 5/10/2005 60 Male 10/16/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Required Intervention 11/7/2007 71 Male 146 lb 11/12/2007 Physician Germany
Primary
Concomitant
Heparin-induced Thrombocytopenia Life Threatening 9/25/2007 56 Male 11/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Death 10/15/2007 76 Male 183 lb 10/16/2007 Pharmacist United States
Primary
Concomitant
Ototoxicity Other Serious 9/7/2007 70 Male 167 lb 12/17/2007 Pharmacist United States
Primary
Concomitant
Vomiting Life Threatening 12/10/2007 Female 110 lb 12/23/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Life Threatening 2/13/2008 64 Female 2/18/2008 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Heparin-induced Thrombocytopenia Hospitalization 3/6/2008 36 Female 227 lb 4/10/2008 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 3/8/2008 59 Female 117 lb 4/23/2008 Physician United States
Primary
Secondary
Liver Function Test Abnormal Other Serious 3/10/2003 85 Female 168 lb 4/29/2008 Pharmacist United States
Primary
Concomitant
Therapeutic Product Contamination Life Threatening 3/19/2008 64 Male 276 lb 5/20/2008 Pharmacist United States
Primary
Concomitant
Sinus Tachycardia Hospitalization 64 Female 5/28/2008 United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 4/16/2008 64 Female 5/6/2008 Pharmacist United States
Primary
Concomitant
Compartment Syndrome Hospitalization 6/1/2008 83 Female 6/16/2008 Pharmacist United States
Primary
Concomitant
Hepatitis Fulminant Life Threatening 4/2/2008 Male 7/2/2008 Other Health Professional France
Primary
Secondary
Concomitant
Peripheral Ischaemia Death 5/24/2008 76 Female 7/3/2008
Primary
Secondary
Concomitant
Fatigue Hospitalization 4/25/2008 Male 6/28/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 7/31/2008 United States
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/14/2008 78 Male 229 lb 8/14/2008 Pharmacist United States
Primary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/11/2008 United States
Primary
Secondary
Concomitant
Wrong Drug Administered 6/23/2008 United States
Primary
Secondary
Upper Gastrointestinal Haemorrhage Hospitalization 6/5/2008 Female 99 lb 8/26/2008 Physician Philippines
Primary
Secondary
Concomitant
Vomiting Hospitalization 5/20/2008 78 Male 216 lb 8/22/2008 United States
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 7/19/2008 Male 185 lb 9/26/2008 United States
Primary
Concomitant
Pulmonary Artery Stenosis Other Serious 5 Female 10/13/2008
Primary
Secondary
Small For Dates Baby Death Male 1 lb 10/15/2008 Other Health Professional Mexico
Primary
Secondary
Shunt Blood Flow Excessive Other Serious 26 Female 10/15/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Hypotension Hospitalization 9/28/2008 67 Female 10/17/2008 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 5/10/2005 60 Male 10/23/2008 Physician United States
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 6/2/2004 6 Male 11/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Required Intervention 6/19/2008 82 Male 245 lb 6/24/2008 Pharmacist United States
Primary
Concomitant
Haemoptysis Required Intervention 9/25/2008 81 Male 10/20/2008 Pharmacist United States
Primary
Concomitant
International Normalised Ratio Increased Other Serious 3/10/2003 85 Female 185 lb 12/4/2008 Pharmacist United States
Primary
Concomitant
Restlessness Other Serious 11/10/2008 72 Female 12/4/2008 Pharmacist United States
Primary
Concomitant
Liver Function Test Abnormal Other Serious 3/10/2003 85 Female 168 lb 12/12/2008 Pharmacist United States
Primary
Concomitant
Speech Disorder Other Serious 12/8/2008 69 Male 196 lb 12/10/2008 Pharmacist United States
Primary
Concomitant
Sickle Cell Anaemia Other Serious 10/1/2008 59 Female 130 lb 1/8/2009 Pharmacist United States
Primary
Concomitant
Restlessness Other Serious 11/10/2008 72 Female 1/30/2009 Other Health Professional Ireland
Primary
Concomitant
Thrombocytopenia Hospitalization 1/21/2009 Male 174 lb 2/11/2009 Physician Argentina
Primary
Secondary
Concomitant
Mental Status Changes Other Serious 8/1/2008 Male 2/24/2009 Pharmacist United States
Primary
Concomitant
Thrombocytopenia Other Serious 12/1/2005 47 Female 126 lb 2/19/2009 Physician United States
Primary
Concomitant
Troponin Increased Death 11/1/2008 Male 188 lb 3/12/2009 Pharmacist United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 8/10/2000 57 Male 344 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 2/17/2009 34 Male 300 lb 2/18/2009 Pharmacist United States
Primary
Concomitant
Unresponsive To Stimuli Life Threatening 4/26/2009 51 Male 271 lb 5/5/2009 Pharmacist United States
Primary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/21/2004 Female 148 lb 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vasculitis Disability 5/1/2003 65 Female 5/26/2009 Physician Spain
Primary
Concomitant
Drug Resistance Hospitalization 71 Female 6/8/2009 United States
Primary
Concomitant
Skin Necrosis Other Serious 64 Female 176 lb 6/11/2009 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Life Threatening 7/21/2004 Female 148 lb 6/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhagic Stroke Life Threatening 4/2/2009 Female 105 lb 4/11/2009 Pharmacist United States
Primary
Concomitant
Orchitis Other Serious 12/9/2008 Male 176 lb 6/30/2009 Other Health Professional United States
Primary
Concomitant
Pyrexia Hospitalization 3/3/2009 Male 7/14/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Cardiac Failure Congestive Life Threatening 5/11/2009 Male 203 lb 7/15/2009 Canada
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 58 Female 214 lb 7/22/2009 Consumer United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2009 Male 7/28/2009 Physician United States
Primary
Concomitant
Skin Lesion Other Serious 1/1/2005 59 Male 7/28/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Skin Lesion Other Serious 1/1/2005 59 Male 7/29/2009 Other Health Professional United States
Primary
Secondary
Concomitant
International Normalised Ratio Decreased 58 Female 214 lb 7/22/2009 Consumer United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 49 Male 8/14/2009 United States
Primary
Concomitant
Respiratory Distress Death 1/1/2007 82 Female 123 lb 8/26/2009 Consumer United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Vomiting Hospitalization 49 Male 9/1/2009 Lawyer United States
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 9/1/2009 Lawyer United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/2/2009 Lawyer United States
Primary
Concomitant
Uterine Leiomyoma Hospitalization 49 Female 9/3/2009 United States
Primary
Concomitant
Vitamin D Deficiency Death 80 Female 9/4/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 79 Female 9/8/2009 United States
Primary
Concomitant
Vomiting Death 3/2/2008 69 Female 9/8/2009 United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 9/9/2009 United States
Primary
Concomitant
Traumatic Lung Injury Death 70 Male 9/10/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 9/14/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 9/16/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 49 Male 9/17/2009 United States
Primary
Concomitant
Heparin-induced Thrombocytopenia Required Intervention 11/4/2008 68 Female 254 lb 11/12/2008 Pharmacist United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 59 Male 9/22/2009 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 77 Female 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 9/25/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 9/28/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2009 79 Female 139 lb 10/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 51 Female 10/9/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization Male 10/15/2009 Lawyer United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 8/18/2009 79 Female 139 lb 10/21/2009 Consumer United States
Primary
Secondary
Concomitant
Lip Swelling Other Serious 6/2/2009 87 Female 121 lb 10/19/2009 Pharmacist United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 5/27/2005 58 Male 195 lb 10/17/2009 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 59 Male 10/17/2009 United States
Primary
Concomitant
Ventricular Failure Hospitalization 49 Female 10/16/2009 Lawyer United States
Primary
Concomitant
Vomiting Death 3/2/2008 78 Female 10/17/2009 United States
Primary
Concomitant
Traumatic Lung Injury Hospitalization 70 Male 10/20/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/14/2008 60 Female 10/20/2009 United States
Primary
Concomitant
Vomiting Hospitalization 49 Male 10/22/2009 United States
Primary
Concomitant

Drug Data