Digoxin combined with Frusemide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Paraesthesia Life Threatening 10/1/2004 73 Male 1/18/2006 Consumer Australia
Primary
Concomitant
Thrombocytopenia Other Serious 4/27/2005 Male 162 lb 1/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hepatic Failure Death 81 Female 2/3/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 2/13/2006 Consumer Australia
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 1/4/2006 78 Female 2/15/2006 United Kingdom
Primary
Concomitant
Hypertension Required Intervention 11/1/2003 49 Male 3/8/2006 Physician United States
Primary
Secondary
Concomitant
Aortic Dissection Death Male 3/29/2006
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 10/30/2005 86 Male 5/2/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 4/4/2006 73 Female 5/4/2006
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 4/4/2006 91 Male 5/3/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Haemoglobin Decreased Life Threatening 4/4/2006 73 Female 5/5/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tooth Extraction Other Serious 74 Male 5/8/2006 Australia
Primary
Concomitant
Visual Acuity Reduced Hospitalization 8/30/2005 89 Female 121 lb 5/16/2006 Other Health Professional Australia
Primary
Concomitant
Telangiectasia Hospitalization 9/19/2005 73 Female 111 lb 6/13/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 4/26/2006 36 Female 117 lb 1/11/2007 Physician Ireland
Primary
Concomitant
Hyperkalaemia Hospitalization 78 Male 1/29/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 56 Male 1/26/2007 Other Health Professional India
Primary
Concomitant
Paraesthesia Other Serious 68 Unknown 172 lb 3/1/2007 Other Health Professional United Kingdom
Primary
Secondary
Haemoglobin Decreased Hospitalization 2/8/2007 86 Male 3/12/2007 Physician
Primary
Secondary
Concomitant
Rash Other Serious Male 176 lb 3/16/2007 Physician Australia
Primary
Concomitant
Purpura Life Threatening 10/19/2006 72 Male 3/23/2007
Primary
Concomitant
Rash Other Serious Male 176 lb 3/23/2007 Physician Australia
Primary
Concomitant
Liver Function Test Abnormal Other Serious 2/24/2007 72 Male 3/28/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Failure Hospitalization 11/23/2006 92 Male 4/20/2007 Consumer Australia
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/31/2006 79 Male 211 lb 4/20/2007 Other Health Professional Ireland
Primary
Concomitant
Palpitations Other Serious 8/1/2006 38 Female 5/10/2007 Physician United Kingdom
Primary
Concomitant
Retinopathy Other Serious 3/1/2006 Female 5/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/31/2006 79 Male 211 lb 5/25/2007 Consumer United Kingdom
Primary
Concomitant
Vomiting Other Serious 10 Female 5/18/2007 United States
Primary
Concomitant
Weight Increased Other Serious 1/31/2006 72 Male 211 lb 6/29/2007 Ireland
Primary
Concomitant
Overdose Disability 80 Female 6/29/2007 Physician United Kingdom
Primary
Concomitant
Circulatory Collapse Life Threatening 85 Female 8/7/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Hospitalization 7/18/2007 66 Male 329 lb 8/24/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 8/4/2007 58 Female 291 lb 8/24/2007 Consumer United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 8/28/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 7/28/2007 58 Female 291 lb 9/19/2007 Physician United Kingdom
Primary
Concomitant
Thrombocytopenia Life Threatening 2/19/1999 89 Female 10/10/2007 France
Primary
Concomitant
Pulmonary Oedema Hospitalization 10/6/2007 61 Male 150 lb 10/15/2007 Physician United Kingdom
Primary
Concomitant
Gastric Ulcer Perforation Other Serious 82 Male 176 lb 10/22/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Other Serious Male 11/15/2007 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Skin Ulcer Other Serious 11/6/2007 Male 11/29/2007 Other Health Professional United Kingdom
Primary
Concomitant
Anaemia Other Serious 8/17/2007 79 Male 12/10/2007 Consumer Italy
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Vomiting Hospitalization 5/27/2006 89 Male 12/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bone Marrow Disorder Other Serious 11/24/2006 Male 216 lb 12/19/2007 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 4/26/2006 Female 117 lb 12/28/2007 Physician Ireland
Primary
Concomitant
Myopathy Hospitalization 7/1/2007 Female 3/9/2008 Physician Australia
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 9/11/2008 54 Male 9/17/2008 Consumer Australia
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 9/11/2008 Male 9/24/2008 Consumer Australia
Primary
Secondary
Concomitant
Venous Pressure Jugular Increased Required Intervention 81 Female 9/22/2008 Other Health Professional United Kingdom
Primary
Concomitant
Shunt Blood Flow Excessive Other Serious 26 Female 10/15/2008 Other Health Professional Mexico
Primary
Secondary
Concomitant
Muscle Twitching Other Serious 1/1/2006 78 Female 10/22/2008 United Kingdom
Primary
Concomitant
Vomiting Other Serious 7/17/2006 Female 10/22/2008 Denmark
Primary
Concomitant
Therapeutic Response Decreased Other Serious 67 Female 11/10/2008 United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization 10/16/2008 12/18/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Embolism Hospitalization 9/1/2008 71 Male 1/9/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Sepsis Hospitalization 6/29/2008 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infection Hospitalization 8/19/2007 Male 1/13/2009 United Kingdom
Primary
Concomitant
Infective Exacerbation Of Chronic Obstructive Airways Disease Hospitalization 8/19/2007 Male 1/14/2009 United Kingdom
Primary
Concomitant
Cardiac Failure Death 12/24/2008 1/16/2009 Physician India
Primary
Concomitant
Death Other Serious 70 1/28/2009 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization Unknown 1/22/2009 Pharmacist United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 9/28/2008 Male 209 lb 2/10/2009 United Kingdom
Primary
Concomitant
Restlessness Hospitalization 7/21/2006 2/10/2009 Other Health Professional Australia
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/2/2008 Female 2/18/2009 Physician United Kingdom
Primary
Concomitant
Cardiac Failure Death 12/24/2008 2/23/2009 Physician India
Primary
Concomitant
Pulmonary Oedema Hospitalization 4/2/2008 Female 3/6/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 81 Male 3/5/2009 United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 3/30/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 4/1/2009 Consumer United Kingdom
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/2/2009 Other Health Professional
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/6/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/7/2009
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 4/8/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/10/2009 Pharmacist Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Hospitalization 3/10/2009 82 Male 4/15/2009 Pharmacist Japan
Primary
Secondary
Tonic Convulsion Hospitalization 3/10/2009 82 Male 4/20/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Vertigo Hospitalization 2/22/2008 4/20/2009 Other Health Professional Singapore
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 4/21/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/22/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/10/2009 82 Male 4/23/2009
Primary
Secondary
Concomitant
Cardiac Failure Congestive Hospitalization 1/1/2009 Female 4/24/2009 Consumer Australia
Primary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/27/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tachycardia Hospitalization 3/10/2009 82 Male 4/28/2009
Primary
Secondary
Concomitant
Gout Other Serious 3/21/2009 4/28/2009 Physician Hong Kong
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 4/29/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/10/2009 82 Male 5/6/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 5/13/2009 Pharmacist United Kingdom
Primary
Secondary
Concomitant
Hypertension Death 12/29/2008 Male 5/15/2009 United Kingdom
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 5/19/2009 Other Health Professional United Kingdom
Primary
Secondary
Accidental Overdose Other Serious 9/13/2007 72 Male 5/20/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Nocturnal Dyspnoea Other Serious 1/1/2008 Male 5/21/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Angioedema Life Threatening 1/12/2009 5/21/2009 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Death 12/29/2008 Male 5/26/2009 United Kingdom
Primary
Concomitant
Flatulence Other Serious 4/4/2007 78 Male 5/26/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Rheumatoid Arthritis Death 12/29/2008 Male 5/29/2009 United Kingdom
Primary
Concomitant
Drug Interaction Hospitalization 53 Female 6/22/2009 Nepal
Primary
Concomitant
Interacting
Flatulence Other Serious 4/4/2007 78 Male 6/22/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 1/9/2009 Female 148 lb 6/22/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 7/4/2003 Male 193 lb 6/23/2009 Physician United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/30/2003 Male 6/25/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Gout Other Serious 3/21/2009 73 7/21/2009 Other Health Professional Hong Kong
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 7/24/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Syncope Life Threatening 6/15/2009 Female 7/29/2009 Consumer United Kingdom
Primary
Secondary
Concomitant
Syncope Life Threatening 6/15/2009 Female 8/5/2009 Consumer Australia
Primary
Secondary
Concomitant
Tonic Convulsion Hospitalization 3/8/2009 82 Male 8/12/2009 Pharmacist Japan
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 8/27/2009 Male 139 lb 11/3/2009 United Kingdom
Primary
Secondary
Concomitant
Polyp Other Serious 2/4/2004 77 Female 11/6/2009 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 78 Female 11/2/2009 Consumer United Kingdom
Primary
Concomitant
Polyp Other Serious 2/4/2004 77 Female 11/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/26/2006 Female 117 lb 11/30/2009 Physician Ireland
Primary
Concomitant
Ventricular Tachycardia Other Serious 6/1/2009 59 Male 166 lb 12/4/2009 Other Health Professional Australia
Primary
Concomitant
Mental Disorder Hospitalization Male 12/8/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Secondary
Bile Duct Cancer Life Threatening 70 Female 143 lb 12/10/2009 Other Health Professional United Kingdom
Primary
Concomitant
Extrapulmonary Tuberculosis Other Serious 7/19/2004 Female 163 lb 12/11/2009 United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization Male 12/7/2009 United Kingdom
Primary
Concomitant
Mental Disorder Hospitalization Male 12/8/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/17/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Ventricular Tachycardia Other Serious 8/26/2009 59 12/21/2009 Other Health Professional Australia
Primary
Concomitant
Ventricular Tachycardia Other Serious 68 Male 172 lb 12/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Skin Ulcer Other Serious 11/6/2007 Male 223 lb 1/13/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pain Other Serious 6/19/2007 60 Male 1/12/2010 Other Health Professional United Kingdom
Primary
Concomitant
Ejection Fraction Decreased Life Threatening 6/1/2009 Female 170 lb 1/15/2010 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Death 5/13/2008 81 Male 159 lb 2/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Death 86 Female 2/2/2010 United States
Primary
Concomitant
Ventricular Tachycardia Other Serious 8/26/2009 59 Male 166 lb 2/15/2010 Other Health Professional Australia
Primary
Concomitant
Left Ventricular Failure Hospitalization 8/15/2009 Female 214 lb 2/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Hospitalization 87 Male 86 lb 2/16/2010 Japan
Primary
Concomitant
Renal Failure Life Threatening 6/1/2009 Female 170 lb 3/18/2010 Physician United Kingdom
Primary
Concomitant
Vertigo Hospitalization 2/22/2008 59 Female 3/19/2010 Other Health Professional Singapore
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 0 Male 4/30/2010 India
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 59 Male 5/13/2010 Consumer Australia
Primary
Concomitant
Renal Failure Acute Other Serious 86 Female 5/14/2010 Consumer Australia
Primary
Secondary
Concomitant
Pulmonary Oedema Other Serious 32 Female 5/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Reflux Oesophagitis Hospitalization 4/18/2010 79 Female 5/25/2010 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 32 Female 5/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Bronchospasm Life Threatening 5/17/2010 89 Female 6/4/2010 Consumer United Kingdom
Primary
Concomitant
Bronchospasm Life Threatening 5/17/2010 89 Female 6/10/2010 Other Health Professional United Kingdom
Primary
Concomitant
Waldenstrom's Macroglobulinaemia Other Serious 5/10/2010 70 Male 164 lb 6/16/2010 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 60 Female 6/11/2010 United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 59 Male 231 lb 7/2/2010 Australia
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Hospitalization 8/20/2010 24 Female 128 lb 8/27/2010 Physician India
Primary
Secondary
Concomitant

Drug Data