Digoxin combined with Folic Acid

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
International Normalised Ratio Increased 2/2/2005 59 9/12/2005 Physician United States
Primary
Concomitant
Pruritus Death 7/22/2004 Male 187 lb 1/25/2006 United Kingdom
Primary
Concomitant
Sudden Death Hospitalization 61 Female 101 lb 1/23/2006 Pharmacist United States
Primary
Concomitant
Rash 88 Male 138 lb 12/7/2005 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 12/9/2004 Male 157 lb 2/9/2006 United Kingdom
Primary
Concomitant
Staphylococcal Sepsis Life Threatening 9/13/2005 71 Male 146 lb 2/1/2006 Physician France
Primary
Concomitant
Sepsis Life Threatening 12/27/2005 69 Male 200 lb 2/8/2006 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 9/1/2002 65 Male 170 lb 2/21/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/1999 67 Male 209 lb 2/24/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 12/24/2005 57 Male 3/3/2006 Other Health Professional United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 3/3/2006 Other Health Professional United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2000 54 Male 229 lb 3/6/2006 Physician United States
Primary
Concomitant
Superinfection Hospitalization 11/24/2005 77 Male 130 lb 2/20/2006 Other Health Professional United States
Primary
Concomitant
Vomiting Hospitalization 2/8/2006 71 Female 140 lb 3/3/2006 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 10/6/2005 74 Male 168 lb 3/9/2006 Pharmacist United States
Primary
Concomitant
Abscess Other Serious 3/8/2006 Male 165 lb 3/15/2006 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 10/1/2004 94 Female 103 lb 12/27/2005 Consumer United States
Primary
Concomitant
Breast Cancer Other Serious 12/16/2005 Female 135 lb 3/28/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 1/1/2000 54 Male 229 lb 3/31/2006 Physician United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2005 Female 186 lb 4/4/2006 Physician United States
Primary
Secondary
Concomitant
Thoracic Vertebral Fracture Hospitalization 9/1/2004 65 Female 3/24/2006 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 2/9/2006 70 Male 170 lb 4/10/2006 Physician Canada
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 4/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Abscess Other Serious 3/8/2006 Male 165 lb 4/17/2006 Consumer Canada
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2000 54 Male 229 lb 4/19/2006 Physician United States
Primary
Concomitant
Prothrombin Time Prolonged Hospitalization 3/6/2006 Female 4/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pulmonary Toxicity Required Intervention 4/26/2005 72 Male 175 lb 4/20/2006 Pharmacist United States
Primary
Concomitant
Rash 11/3/2005 92 Male 1/25/2006 Consumer United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Hospitalization 2/1/2004 63 Male 154 lb 5/4/2006 Lawyer United States
Primary
Concomitant
Peripheral Sensory Neuropathy Hospitalization 12/12/2005 67 Male 368 lb 12/27/2005 Pharmacist United States
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/11/2006 Physician Spain
Primary
Concomitant
Lung Neoplasm Malignant Other Serious 7/1/2005 Male 5/12/2006 Physician United States
Primary
Concomitant
Breast Cancer Hospitalization 8/1/2005 76 Female 121 lb 1/24/2006 Physician United States
Primary
Concomitant
Sepsis Hospitalization 9/25/2005 Female 108 lb 5/19/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hyperphosphataemia Other Serious 4/20/2006 Female 5/22/2006 Physician Spain
Primary
Concomitant
Dyspepsia 2/1/2006 89 Male 137 lb 4/3/2006 Consumer United States
Primary
Concomitant
Pneumothorax Hospitalization 5/8/2006 42 Female 5/22/2006 Other Health Professional United States
Primary
Concomitant
Plasma Viscosity Decreased Other Serious 5/13/2006 85 Female 100 lb 5/30/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Basal Cell Carcinoma Other Serious 7/1/2005 Male 6/9/2006 Physician United States
Primary
Concomitant
Vomiting Hospitalization 2/8/2006 71 Female 140 lb 6/7/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Oral Candidiasis 1/1/2006 67 Female 135 lb 4/25/2006 Pharmacist United States
Primary
Concomitant
Lethargy Other Serious 5/1/2006 78 Male 6/14/2006 Consumer United States
Primary
Concomitant
Skin Nodule Hospitalization 10/1/2003 Female 119 lb 6/22/2006 Germany
Primary
Concomitant
Oedema Peripheral Other Serious 4/11/2006 60 Female 6/23/2006 Physician United States
Primary
Concomitant
Blood Creatinine Increased 5/10/2006 71 Female 6/30/2006 Consumer United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 52 Female 132 lb 7/13/2006 Pharmacist United States
Primary
Secondary
Concomitant
Pericarditis Constrictive Hospitalization 10/1/2003 Female 119 lb 7/20/2006 Germany
Primary
Concomitant
Musculoskeletal Pain Other Serious 2/27/2006 72 Female 148 lb 7/24/2006 Consumer United States
Primary
Concomitant
Dyspnoea Exertional Hospitalization 4/8/2006 Male 7/19/2006 Pharmacist United States
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 5/5/2001 77 Male 7/21/2006 United States
Primary
Concomitant
Dyspnoea Death 5/24/2005 50 Male 5/24/2006 Physician United States
Primary
Concomitant
Skin Laceration Hospitalization 6/3/2006 Female 101 lb 7/27/2006 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 1/1/2003 79 Female 154 lb 8/1/2006 Consumer United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/14/2005 80 Male 8/1/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased 10/1/2005 74 Female 8/4/2006 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/1/2006 85 Female 208 lb 7/31/2006 United States
Primary
Concomitant
Multi-organ Failure Other Serious 7/2/2006 77 Female 99 lb 7/21/2006 Physician United Kingdom
Primary
Concomitant
Urinary Incontinence 2/10/2006 Male 125 lb 8/8/2006 Consumer United States
Primary
Concomitant
Wrist Fracture Other Serious 5/1/2006 78 Male 121 lb 8/7/2006 Consumer United States
Primary
Concomitant
Tremor Disability 4/23/2005 87 Female 95 lb 8/14/2006 Consumer United States
Primary
Concomitant
Thinking Abnormal Other Serious 3/1/2006 65 Male 215 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint Other Serious 7/10/2006 64 Female 170 lb 8/16/2006 United States
Primary
Concomitant
Vomiting Other Serious 88 Female 8/18/2006 United Kingdom
Primary
Concomitant
Prothrombin Time Shortened Death 5/7/2006 66 Male 154 lb 8/14/2006 Physician Spain
Primary
Secondary
Concomitant
Renal Failure Hospitalization 8/1/2006 Male 9/4/2006 Physician United States
Primary
Secondary
Concomitant
Arthritis Bacterial Hospitalization 5/1/2006 Male 9/6/2006 Physician United Kingdom
Primary
Concomitant
Arteriosclerosis Coronary Artery Hospitalization 9/1/2005 56 Female 8/31/2006 Consumer United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/6/2004 Male 214 lb 9/7/2006 Australia
Primary
Concomitant
Vomiting Hospitalization 8/1/2006 77 Male 150 lb 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2005 Female 186 lb 9/12/2006 Physician United States
Primary
Secondary
Concomitant
Septic Arthritis Staphylococcal Hospitalization 4/27/2006 Male 148 lb 9/14/2006 Physician United Kingdom
Primary
Concomitant
Weight Increased Other Serious 8/1/2006 80 Female 130 lb 9/8/2006 United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Hospitalization 6/23/2006 46 Male 9/8/2006 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 7/10/2006 64 Female 170 lb 9/12/2006 United States
Primary
Concomitant
Vascular Calcification Life Threatening 10/15/2005 67 Male 183 lb 9/28/2006 United States
Primary
Concomitant
Vomiting Hospitalization 8/1/2006 77 Male 150 lb 10/11/2006 Physician United States
Primary
Secondary
Concomitant
Scar Other Serious 8/1/2006 Female 10/16/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Death 1/1/2004 68 10/25/2006 Consumer United States
Primary
Secondary
Concomitant
Myelofibrosis Other Serious 1/1/2006 73 Male 237 lb 10/27/2006 Other Health Professional United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 11/8/2006 Other Health Professional France
Primary
Secondary
Concomitant
Alopecia 6/1/2005 78 Female 11/13/2006 Consumer United States
Primary
Concomitant
Pemphigoid Hospitalization 8/15/2006 Female 11/13/2006 Other Health Professional United Kingdom
Primary
Concomitant
Chest Pain Hospitalization 11/9/2006 50 Male 11/17/2006 United States
Primary
Concomitant
Neutropenia Other Serious 5/23/2005 75 Male 11/15/2006 Pharmacist United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Other Serious 5/21/2005 74 Male 11/15/2006 United States
Primary
Secondary
Concomitant
Death Death 10/17/2006 71 Male 11/17/2006 Other Health Professional United States
Primary
Concomitant
Myelodysplastic Syndrome Other Serious 9/15/2006 95 Male 150 lb 11/16/2006 Physician United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 11/1/2006 50 Male 12/7/2006 United States
Primary
Concomitant
Speech Disorder Other Serious 11/2/2006 89 Female 113 lb 11/30/2006 Consumer United States
Primary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 12/6/2006 Physician Spain
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 12/18/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pyrexia Other Serious 1/1/2006 73 Male 230 lb 12/7/2006 Physician United States
Primary
Concomitant
Urine Output Increased Other Serious 6/13/2006 89 Male 183 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Convulsion Hospitalization 10/15/2006 Male 141 lb 1/9/2007 Other Health Professional United Kingdom
Primary
Concomitant
Thinking Abnormal 3/1/2006 65 Male 215 lb 10/19/2006 United States
Primary
Secondary
Concomitant
Dry Throat 59 Female 205 lb 10/24/2006 Qatar
Primary
Concomitant
Vomiting Hospitalization 1/1/2006 86 Female 118 lb 1/11/2007 Consumer United States
Primary
Secondary
Concomitant
Osteonecrosis Other Serious 5/1/2005 63 Female 157 lb 11/28/2006 Physician United States
Primary
Concomitant
Fatigue 9/1/2006 85 Female 11/7/2006 Consumer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 11/24/2006 50 Female 1/12/2007 Other Health Professional Germany
Primary
Secondary
Concomitant
Drug Ineffective Other Serious 1/1/2003 61 Male 10/5/2006 Other Health Professional United States
Primary
Concomitant
Cardiac Failure Death Male 112 lb 1/19/2007 Physician Venezuela
Primary
Concomitant
Pneumonia Hospitalization 1/15/2007 78 Male 169 lb 1/24/2007 Other Health Professional United States
Primary
Concomitant
Vertigo Hospitalization 7/1/2000 67 Female 1/30/2007 Physician United States
Primary
Concomitant
Embolism Other Serious 1/25/2007 54 Male 164 lb 2/6/2007 Consumer United States
Primary
Concomitant
Palpitations Other Serious 84 Female 115 lb 8/17/2006 United States
Primary
Concomitant
Pyuria Other Serious 2/12/2007 Male 235 lb 2/27/2007 Pharmacist United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/15/2005 64 Male 10/23/2006 Pharmacist United States
Primary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Pulmonary Fibrosis Other Serious 79 Male 220 lb 3/7/2007 Physician United Kingdom
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 58 Male 3/15/2007 Consumer United States
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 3/9/2007 United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 3/10/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2007 75 Male 137 lb 3/9/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 3/13/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Vitamin B12 Decreased Other Serious 12/19/2006 Female 3/13/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 3/12/2007 United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Required Intervention 9/28/2004 53 Male 183 lb 11/17/2005 Physician United States
Primary
Secondary
Concomitant
Spinal Column Stenosis Other Serious 1/1/1999 Male 235 lb 3/29/2007 Physician United States
Primary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/1/2007 75 Male 137 lb 3/26/2007 Pharmacist United States
Primary
Concomitant
Renal Failure Acute Life Threatening 2/6/2007 79 Male 187 lb 2/21/2007 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/26/2007 74 Male 4/2/2007 Physician United States
Primary
Secondary
Concomitant
Pulmonary Embolism Other Serious 2/26/2007 74 Male 4/5/2007 Physician United States
Primary
Secondary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 4/24/2007 Other Health Professional United Kingdom
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 4/30/2007 Other Health Professional France
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity Other Serious 6/13/2006 89 Male 183 lb 5/11/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pancytopenia Other Serious 1/1/2006 80 Male 5/1/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 4/18/2007 72 Female 150 lb 5/15/2007 Pharmacist United States
Primary
Concomitant
Pulmonary Fibrosis Other Serious 79 Male 220 lb 5/14/2007 Physician United Kingdom
Primary
Concomitant
Pneumonia Death 79 Male 220 lb 5/15/2007 Physician United Kingdom
Primary
Concomitant
Pulmonary Embolism Other Serious 2/26/2007 74 Male 5/8/2007 Physician United States
Primary
Secondary
Concomitant
Alopecia 2/2/2007 73 Female 76 lb 5/25/2007 Consumer United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 7/1/2006 12/13/2006 Physician United States
Primary
Secondary
Concomitant
Vitamin D Decreased Required Intervention 5/29/2006 71 Female 141 lb 2/7/2007 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 5/23/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pneumonia Death 79 Male 5/22/2007 United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 1/1/2006 80 Male 5/17/2007 Physician United States
Primary
Concomitant
Pulmonary Fibrosis Death 79 Male 220 lb 5/25/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 12/1/2004 Female 109 lb 5/24/2007 Physician United States
Primary
Concomitant
Thrombocythaemia Other Serious 10/30/2006 88 Female 110 lb 6/11/2007 Other Health Professional Portugal
Primary
Concomitant
Hypergammaglobulinaemia Benign Monoclonal Other Serious 4/10/2007 Female 110 lb 6/11/2007 Other Health Professional United Kingdom
Primary
Concomitant
Cardiac Flutter Other Serious 3/1/2003 68 Female 6/21/2007 Consumer United States
Primary
Secondary
Concomitant
Renal Disorder 10/1/2005 64 Male 179 lb 6/14/2007 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 2/26/2007 74 Male 6/12/2007 Physician United States
Primary
Concomitant
Oedema Hospitalization 1/1/2005 86 Female 4/24/2007 Physician United States
Primary
Concomitant

Drug Data