Digoxin combined with Fluconazole

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Rectal Haemorrhage Hospitalization 75 Male 1/10/2006 Physician France
Primary
Secondary
Concomitant
International Normalised Ratio Increased 8/24/2004 65 9/12/2005 Physician United States
Primary
Concomitant
Pancytopenia Hospitalization 11/3/2005 79 Male 1/18/2006 Physician United States
Primary
Concomitant
Gamma-glutamyltransferase Increased Hospitalization 1/23/2006 91 Female 154 lb 2/28/2006 Consumer France
Primary
Secondary
Concomitant
Skin Maceration Hospitalization 12/31/2005 89 Female 168 lb 2/23/2006 Pharmacist United States
Primary
Concomitant
Injection Site Reaction Death 11/16/2005 66 Male 146 lb 11/30/2005 Pharmacist United States
Primary
Concomitant
Obstruction Hospitalization 74 Male 3/16/2006 Pharmacist United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 3/29/2006 72 Male 229 lb 5/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Plasma Viscosity Decreased Other Serious 5/13/2006 85 Female 100 lb 5/30/2006 Consumer United States
Primary
Secondary
Concomitant
Respiratory Failure Other Serious 7/29/2005 77 Male 225 lb 6/8/2006 Consumer France
Primary
Secondary
Concomitant
Pyrexia Other Serious 6/28/2006 68 Male 7/17/2006 Physician Spain
Primary
Concomitant
Pancytopenia Death 11/3/2005 79 Male 7/18/2006 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/4/2006 Physician Spain
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 6/28/2006 68 Male 8/24/2006 Physician Spain
Primary
Concomitant
Rash Pruritic Hospitalization 8/14/2006 81 Female 121 lb 8/30/2006 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 62 Male 11/16/2006 Consumer Japan
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/21/2006
Primary
Concomitant
Xanthopsia Other Serious 62 Male 12/14/2006 Physician Japan
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 12/27/2006 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 1/2/2007 52 Female 134 lb 1/17/2007 United States
Primary
Concomitant
Localised Infection Other Serious 4/1/2006 57 Male 255 lb 1/30/2007 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2007 52 Female 134 lb 1/24/2007 United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/2/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 2/12/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 3/28/2007 Other Health Professional United States
Primary
Concomitant
Fluid Retention 1/11/2006 49 Female 320 lb 1/23/2007 Consumer United States
Primary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 4/19/2007 Physician United States
Primary
Secondary
Concomitant
Vomiting Required Intervention 3/6/2007 62 4/17/2007 Pharmacist United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 4/27/2007 Physician United States
Primary
Concomitant
Vomiting Other Serious 10/1/2005 Male 180 lb 5/2/2007 Physician United States
Primary
Concomitant
Viral Tracheitis Hospitalization 1/31/2007 74 Male 145 lb 4/23/2007 Physician United States
Primary
Secondary
Concomitant
Retroperitoneal Lymphadenopathy Required Intervention 7/1/2002 60 Female 4/24/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Retroperitoneal Lymphadenopathy Required Intervention 9/1/2006 60 Female 5/24/2007 Other Health Professional United States
Primary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 6/5/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/22/2007 82 Female 8/6/2007 Other Health Professional United States
Primary
Concomitant
Mucosal Inflammation Other Serious 6/1/2007 1 Female 53 lb 8/7/2007 Other Health Professional United States
Primary
Concomitant
Rhabdomyolysis Hospitalization 76 Male 8/3/2007 Finland
Primary
Secondary
Concomitant
Blood Creatinine Increased Hospitalization 5/21/2007 Male 5/22/2007 United States
Primary
Concomitant
Tracheal Injury Death 2/13/2007 Male 145 lb 8/28/2007 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/27/2007 47 Male 159 lb 8/17/2007 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/27/2007 47 Male 159 lb 8/22/2007 Physician Canada
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 76 Male 9/1/2007 Other Health Professional Finland
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 7/27/2007 47 Male 159 lb 9/4/2007 Physician Canada
Primary
Secondary
Concomitant
Thrombocytopenia Life Threatening 2/19/1999 89 Female 10/10/2007 France
Primary
Concomitant
Staphylococcal Bacteraemia Other Serious 6/1/2007 1 Female 53 lb 10/23/2007 Physician United States
Primary
Concomitant
Polyp Other Serious 3 Male 11/2/2007
Primary
Secondary
Pain Other Serious 6/19/2007 68 Male 154 lb 11/22/2007 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 12/10/2007 Female 110 lb 12/23/2007 Physician United States
Primary
Concomitant
Oral Candidiasis 1/1/2004 76 Female 12/28/2007 Consumer United States
Primary
Concomitant
Drug Interaction Other Serious 7/28/1997 65 Female 3/6/2008 Belgium
Primary
Concomitant
Interacting
Pyrexia Life Threatening 66 Female 152 lb 3/11/2008 Pharmacist United States
Primary
Secondary
Concomitant
Septic Shock Required Intervention 1/23/2008 56 Male 293 lb 3/20/2008 Physician Germany
Primary
Concomitant
Vomiting Hospitalization 5/15/2008 61 Female 150 lb 6/9/2008 United States
Primary
Concomitant
Incontinence Hospitalization 5/1/2008 82 Female 176 lb 6/9/2008 United States
Primary
Concomitant
Multiple Myeloma Death 7/27/2008 Male 9/4/2008 Consumer United States
Primary
Concomitant
Pneumocystis Jiroveci Pneumonia Other Serious 7/2/2008 Male 233 lb 9/11/2008 Physician United States
Primary
Concomitant
Multiple Myeloma Death 7/27/2008 Male 9/24/2008 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 8/18/2002 74 Female 137 lb 9/20/2002 Pharmacist United States
Primary
Concomitant
Haptoglobin Decreased Hospitalization 9/14/2008 72 Female 10/15/2008 Physician Denmark
Primary
Concomitant
Haptoglobin Decreased Other Serious 9/14/2008 72 Female 11/4/2008 Physician Denmark
Primary
Concomitant
Pancreatic Carcinoma Other Serious 9/14/2008 72 Female 11/21/2008 Physician Denmark
Primary
Concomitant
Thrombocytopenia Hospitalization 9/18/2008 Male 11/25/2008 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 10/6/2008 78 Female 12/2/2008 Other Health Professional United Kingdom
Primary
Concomitant
Pancreatic Carcinoma Other Serious 9/14/2008 72 Female 12/3/2008 Physician Denmark
Primary
Concomitant
Rash Other Serious 1/12/2009 81 Male 176 lb 1/15/2009 Pharmacist United States
Primary
Concomitant
Rash Other Serious 9/19/2008 67 Male 1/21/2009 Physician United Kingdom
Primary
Concomitant
Skin Ulcer Hospitalization 10/6/2008 78 Female 2/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Venoocclusive Liver Disease Other Serious 12/20/2008 62 Male 2/23/2009 Physician United States
Primary
Secondary
Concomitant
Rash Hospitalization 12/16/2008 79 Male 2/23/2009 Physician United Kingdom
Primary
Concomitant
International Normalised Ratio Increased Other Serious 2/17/2009 76 Male 3/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Sepsis Other Serious 3/14/2009 Female 82 lb 3/24/2009 United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Other Serious 2/17/2009 76 Male 3/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Hospitalization 60 Female 135 lb 4/3/2009 United States
Primary
Concomitant
Tachycardia Other Serious 3/14/2009 Female 82 lb 4/17/2009 United States
Primary
Secondary
Concomitant
Intraventricular Haemorrhage Death 2/22/2009 58 Male 187 lb 4/29/2009 Physician Spain
Primary
Concomitant
Middle Ear Effusion Required Intervention 5/18/2009 Female 107 lb 6/3/2009 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2008 84 Female 113 lb 6/22/2009 United States
Primary
Concomitant
Injury Death 62 Male 7/13/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 7/13/2009 Lawyer United States
Primary
Concomitant
Unevaluable Event Hospitalization 61 Female 7/22/2009 Lawyer United States
Primary
Concomitant
Swelling Hospitalization 72 Female 7/27/2009 United States
Primary
Concomitant
Vomiting Other Serious 3/18/2008 56 Female 258 lb 7/22/2009 United States
Primary
Concomitant
Weight Decreased Other Serious Female 7/31/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Other Serious 3/18/2008 56 Female 258 lb 8/6/2009 Lawyer United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Female 8/5/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/2/2007 52 Female 134 lb 8/7/2009 Other Health Professional United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 39 Female 8/9/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 8/11/2009 United States
Primary
Concomitant
Vision Blurred Other Serious 4/23/2007 54 Female 258 lb 8/12/2009 United States
Primary
Concomitant
Weight Decreased Death 62 Male 8/13/2009 United States
Primary
Concomitant
Rectal Haemorrhage Other Serious 39 Female 8/14/2009 United States
Primary
Concomitant
Unemployment Other Serious 39 Female 8/21/2009 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 8/27/2009 Pharmacist Canada
Primary
Concomitant
Pulmonary Embolism Hospitalization 7/5/2009 Male 8/31/2009 Netherlands
Primary
Concomitant
Vomiting Other Serious 8/1/2009 66 Male 190 lb 9/1/2009 Pharmacist Canada
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 8/27/2009 United States
Primary
Concomitant
Uterine Polyp Hospitalization 61 Female 8/25/2009 United States
Primary
Concomitant
Febrile Neutropenia Hospitalization 6/30/2009 Female 9/2/2009 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Tricuspid Valve Incompetence Hospitalization 62 Male 8/31/2009 United States
Primary
Concomitant
Unevaluable Event Hospitalization 61 Female 8/27/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/1/2009 United States
Primary
Concomitant
Thyroxine Free Increased Other Serious 4/23/2007 54 Female 258 lb 9/2/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 77 Female 9/2/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/23/2007 54 Female 258 lb 9/3/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 5/8/2008 70 Female 9/3/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 9/3/2009 Lawyer United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/11/2009 United States
Primary
Concomitant
Vomiting Hospitalization 61 Female 9/15/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 9/15/2009 United States
Primary
Concomitant
Vitreous Haemorrhage Hospitalization 2/20/2008 65 Female 180 lb 9/15/2009 United States
Primary
Concomitant
Vomiting Hospitalization 89 Female 9/16/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 9/17/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 62 Male 9/18/2009 United States
Primary
Concomitant
Subdural Haemorrhage Other Serious 8/28/2009 Male 9/30/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Wrist Fracture Other Serious 38 Female 9/22/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 76 Female 9/25/2009 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 53 Female 9/29/2009 United States
Primary
Concomitant
Tricuspid Valve Incompetence Hospitalization 62 Male 203 lb 9/25/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Death Male 9/22/2009 United States
Primary
Concomitant
Surgery Hospitalization 72 Female 9/25/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 2/1/2008 84 Female 113 lb 9/25/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 62 Female 180 lb 9/28/2009 United States
Primary
Concomitant
Urinary Tract Infection Other Serious 4/23/2007 54 Female 258 lb 9/24/2009 United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 77 Female 9/23/2009 United States
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 5/18/2008 75 Male 9/30/2009 Physician United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 60 Female 9/29/2009 United States
Primary
Concomitant
Wound Infection Hospitalization 29 Female 276 lb 9/29/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 203 lb 10/10/2009 United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 77 Female 10/10/2009 United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 10/9/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 6/25/2007 69 Female 10/9/2009 United States
Primary
Concomitant
Syncope Hospitalization 11/3/2005 79 Male 10/16/2009 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 69 Female 10/16/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Female 10/17/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 62 Male 203 lb 10/16/2009 United States
Primary
Concomitant
Transient Ischaemic Attack Hospitalization 61 Female 10/17/2009 Lawyer United States
Primary
Concomitant
Joint Injury Other Serious 8/19/2009 Female 185 lb 10/23/2009 Brazil
Primary
Concomitant
Thyroid Cyst Hospitalization 11/2/2007 78 Female 10/21/2009 United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 61 Male 10/22/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 10/22/2009 Lawyer United States
Primary
Concomitant
Wrist Fracture Other Serious 38 Female 10/22/2009 United States
Primary
Concomitant
Therapeutic Agent Toxicity Hospitalization 77 Female 10/23/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 77 Female 10/26/2009 United States
Primary
Concomitant
Ventricular Tachycardia Hospitalization 72 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 10/26/2009 United States
Primary
Concomitant
Swelling Hospitalization 37 Female 218 lb 10/26/2009 Lawyer United States
Primary
Concomitant
Vomiting Hospitalization 2/20/2008 65 Female 10/26/2009 United States
Primary
Concomitant
Weight Decreased Other Serious 6/25/2007 64 Female 11/9/2009 United States
Primary
Concomitant
Urinary Tract Infection Pseudomonal Hospitalization 77 Female 11/4/2009 United States
Primary
Concomitant

Drug Data