Digoxin combined with Enalapril Maleate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Syncope Hospitalization 10/1/2000 Male 1/3/2006 Finland
Primary
Concomitant
Haemarthrosis Hospitalization 6/6/2004 Female 1/4/2006 France
Primary
Concomitant
Refusal Of Treatment By Patient Hospitalization Female 1/4/2006 United States
Primary
Secondary
Concomitant
Refusal Of Treatment By Patient Hospitalization 85 Female 1/5/2006 Physician United States
Primary
Secondary
Sarcoma Hospitalization 1/1/2003 Male 1/18/2006 United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 78 Female 1/19/2006 Physician Greece
Primary
Secondary
Thermal Burn 10/2/2005 Male 12/7/2005 United States
Primary
Concomitant
Venous Pressure Jugular Increased Hospitalization 58 Male 2/10/2006 United States
Primary
Concomitant
Oral Intake Reduced Other Serious 1/1/2006 78 Male 168 lb 2/22/2006 United States
Primary
Concomitant
Drug Ineffective Other Serious 2/14/2006 47 Male 150 lb 2/22/2006 United States
Primary
Concomitant
Mouth Haemorrhage Hospitalization 2/12/2006 Male 3/2/2006 Physician Japan
Primary
Concomitant
Interacting
Hypertension Required Intervention 11/1/2003 49 Male 3/8/2006 Physician United States
Primary
Secondary
Concomitant
Gastrointestinal Infection Hospitalization 85 Female 3/16/2006 Consumer Sweden
Primary
Concomitant
Sudden Death Death 5/1/2005 88 Male 3/14/2006 Physician United States
Primary
Concomitant
Pharmaceutical Product Complaint Other Serious 2/14/2006 47 Male 150 lb 3/24/2006 Physician United States
Primary
Concomitant
Urethral Injury Other Serious 2/8/2005 Male 4/3/2006 Physician Spain
Primary
Concomitant
Ventricular Dysfunction Hospitalization 1/15/2006 78 Female 3/28/2006 Physician France
Primary
Secondary
Concomitant
Rhabdomyolysis Hospitalization 2/4/2006 Female 126 lb 4/7/2006 Physician United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Renal Failure Acute Death 7/5/2005 Male 167 lb 4/18/2006 United States
Primary
Concomitant
Weight Increased Other Serious 10/31/2005 58 Male 186 lb 4/11/2006 United States
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 2/4/2006 66 Female 126 lb 4/6/2006 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 4/1/2002 70 Male 4/27/2006 Canada
Primary
Secondary
Concomitant
Dyspnoea 1/26/2006 70 Female 2/21/2006 United States
Primary
Concomitant
Somnolence 10/13/2005 Female 150 lb 2/21/2006 Physician United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 1/11/2006 79 Female 106 lb 3/27/2006 Pharmacist United States
Primary
Secondary
Concomitant
Death Death 7/5/2005 Male 167 lb 5/10/2006 United States
Primary
Concomitant
Syncope Required Intervention 12/1/2005 77 Female 12/2/2005 Pharmacist United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 4/1/2006 86 Female 160 lb 5/8/2006 Consumer United States
Primary
Secondary
Concomitant
Bronchitis Acute Hospitalization 53 Female 84 lb 5/23/2006 Physician Japan
Primary
Concomitant
Staphylococcal Infection Hospitalization 3/12/2006 56 Male 6/6/2006 Physician United States
Primary
Secondary
Hypertension Other Serious 12/16/2005 73 Male 198 lb 6/22/2006 Physician Spain
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/22/2006 74 Male 225 lb 6/23/2006 Physician United States
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 5/19/2006 United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 4/27/2006 61 Male Pharmacist United States
Primary
Concomitant
Blood Glucose Increased Male 7/21/2006 Consumer United States
Primary
Concomitant
Pulmonary Arterial Pressure Increased Other Serious 3/31/2005 12 Female 68 lb 7/24/2006 Physician Japan
Primary
Concomitant
Liver Function Test Abnormal Other Serious 77 Female 7/21/2006 New Zealand
Primary
Secondary
Concomitant
Therapeutic Response Decreased 11/7/2005 74 Female 8/9/2006 Physician United States
Primary
Concomitant
Pain Other Serious 4/1/2003 78 Female 140 lb 7/5/2006 United States
Primary
Concomitant
Renal Failure Life Threatening 7/7/2006 73 Female 8/17/2006 Other Health Professional South Africa
Primary
Concomitant
Thinking Abnormal Other Serious 3/1/2006 65 Male 215 lb 7/19/2006 United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 7/7/2006 73 Female 8/21/2006 Other Health Professional South Africa
Primary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 9/7/2006 Other Health Professional Japan
Primary
Concomitant
Speech Disorder Hospitalization 77 Female 9/15/2006 Other Health Professional New Zealand
Primary
Concomitant
Viral Infection Other Serious Male 9/28/2006 United States
Primary
Concomitant
Renal Impairment Hospitalization 3/19/2006 78 Female 157 lb 10/3/2006 Physician Argentina
Primary
Concomitant
Myocardial Infarction Other Serious Male 10/6/2006 Consumer United States
Primary
Secondary
Viral Infection Other Serious Male 10/6/2006 Consumer United States
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 10/24/2005 81 Male 10/10/2006 Other Health Professional Japan
Primary
Concomitant
Vomiting Hospitalization 8/18/2006 68 Female 110 lb 9/22/2006 Pharmacist United States
Primary
Concomitant
Neurotoxicity Hospitalization 1/1/2006 77 10/12/2006 Physician New Zealand
Primary
Concomitant
Weight Increased Other Serious 9/1/2006 72 Female 158 lb 10/17/2006 United States
Primary
Concomitant
Dyspnoea 1/27/2006 70 Female 8/22/2006 United States
Primary
Concomitant
Renal Failure Acute Hospitalization 9/23/2006 59 Male 10/26/2006 United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 2/14/2006 84 Male 97 lb 11/2/2006 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Other Serious 4/1/2002 Female 11/10/2006 Physician United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 10/5/2006 91 Female 11/3/2006 Sweden
Primary
Secondary
Concomitant
Therapeutic Response Unexpected With Drug Substitution Other Serious 75 Male 11/3/2006 Physician Finland
Primary
Concomitant
Alopecia 6/1/2005 78 Female 11/13/2006 Consumer United States
Primary
Concomitant
Alopecia 33 Female 11/13/2006 Consumer United States
Primary
Secondary
Vomiting Hospitalization 9/30/2006 69 Female 11/13/2006 Other Health Professional France
Primary
Secondary
Concomitant
Varicose Ulceration Other Serious 8/15/2006 Female 198 lb 11/22/2006 Physician Czech Republic
Primary
Concomitant
Urinary Tract Infection Other Serious 2/14/2006 84 Male 97 lb 11/17/2006 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/1/2006 Other Health Professional France
Primary
Concomitant
Interacting
Pulmonary Arterial Pressure Increased 12 Female 68 lb 11/30/2006 Physician Japan
Primary
Concomitant
Off Label Use Hospitalization 12/12/2005 53 Female 84 lb 11/30/2006 Physician Japan
Primary
Concomitant
Pancytopenia Life Threatening 9/20/2006 75 Male 187 lb 12/1/2006 Pharmacist Spain
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 9/15/2006 70 Male 11/29/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Drug Interaction Other Serious 9/15/2006 70 Male 12/14/2006 Physician Denmark
Primary
Concomitant
Interacting
Respiratory Failure Hospitalization 11/18/2006 62 Male 12/6/2006 Physician Spain
Primary
Concomitant
Thrombosis Death 5/4/2005 Female 155 lb 12/18/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Life Threatening 9/15/2006 70 Male 12/11/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Hypoxia Hospitalization 7/23/2006 81 9/25/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Failure Hospitalization 11/18/2006 62 Male 187 lb 12/18/2006 Physician Spain
Primary
Secondary
Blood Pressure Systolic Increased 5/16/2006 78 Male 12/28/2006 Consumer United States
Primary
Concomitant
Sepsis Other Serious 12/6/2006 Male 30 lb 1/2/2007 Consumer United States
Primary
Concomitant
Renal Failure Other Serious 8/10/2006 80 Male 12/27/2006 Other Health Professional United Kingdom
Primary
Concomitant
Infusion Related Reaction Other Serious 3/10/2004 92 Female 112 lb 8/21/2006 United States
Primary
Concomitant
Urine Output Decreased Hospitalization 11/18/2006 62 Male 187 lb 1/3/2007 Physician Spain
Primary
Secondary
Granulocytopenia Life Threatening 12/12/2006 67 Male 1/2/2007 Germany
Primary
Concomitant
Thinking Abnormal 3/1/2006 65 Male 215 lb 10/19/2006 United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious Male 10/4/2006 Consumer United States
Primary
Secondary
Drug Interaction Other Serious 8/31/2006 74 Male 1/11/2007 Sweden
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Death 10/1/2003 62 Male 200 lb 10/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Parkinsonism Hospitalization 77 Female 2/2/2007 Other Health Professional New Zealand
Primary
Concomitant
Hyperkalaemia Hospitalization 10/31/2006 78 Male 2/8/2007 Pharmacist Spain
Primary
Concomitant
Interacting
Hypertension Life Threatening 1/8/2007 Female 2/12/2007 Physician Bulgaria
Primary
Concomitant
Palpitations Other Serious 1/3/2007 65 Male 195 lb 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Pruritus Hospitalization 10/12/2006 56 Male 2/9/2007 Pharmacist United States
Primary
Concomitant
Swollen Tongue Other Serious 1/20/2007 60 Male 2/26/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Orthopnoea Hospitalization 1/1/2007 62 Male 159 lb 3/7/2007 Physician Switzerland
Primary
Concomitant
Septic Shock Hospitalization 11/18/2006 62 NotSpecified 187 lb 3/6/2007 Physician Spain
Primary
Secondary
Pneumonia Life Threatening 5/2/2001 65 Male 104 lb 3/12/2007 Other Health Professional France
Primary
Concomitant
Thrombocytopenia Other Serious 2/5/2007 77 Male 187 lb 3/14/2007 Other Health Professional United Kingdom
Primary
Concomitant
Bradycardia Hospitalization 2/5/2004 82 Male 177 lb 3/21/2005 United States
Primary
Secondary
Concomitant
Middle Insomnia 9/25/2006 20 Female 111 lb 11/6/2006 Consumer United States
Primary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 3/16/2007 Physician Bulgaria
Primary
Concomitant
Wound Haemorrhage Other Serious 7/7/2006 73 Female 3/19/2007 Other Health Professional South Africa
Primary
Concomitant
Cardiac Failure Congestive Hospitalization 8/1/2000 59 Female 3/19/2007
Primary
Secondary
Concomitant
Melaena Hospitalization 1/22/2007 61 Male 3/28/2007 Pharmacist United States
Primary
Secondary
Concomitant
Hypertension Life Threatening 1/8/2007 Female 4/6/2007 Physician Bulgaria
Primary
Concomitant
White Blood Cell Count Increased Other Serious 2/15/2007 71 Female 161 lb 4/5/2007 Other Health Professional Denmark
Primary
Secondary
Concomitant
Overdose Hospitalization 3/13/2007 74 Male 4/20/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Skin Hyperpigmentation Other Serious 70 Male 5/1/2007 Other Health Professional Greece
Primary
Concomitant
Inappropriate Antidiuretic Hormone Secretion Hospitalization 74 Male 5/4/2007 Other Health Professional Spain
Primary
Concomitant
Muscular Weakness Other Serious 69 Female 2/6/2007 Pharmacist Canada
Primary
Concomitant
Syncope Hospitalization 1/1/2005 86 Male 160 lb 12/13/2006 Consumer United States
Primary
Concomitant
Iron Deficiency Anaemia Hospitalization 8/1/2006 12/13/2006 Physician United States
Primary
Concomitant
Anaphylactic Reaction Life Threatening 5/31/2006 67 Male 1/18/2007 Physician United States
Primary
Concomitant
White Blood Cell Count Decreased Death 3/14/2007 79 Female 5/24/2007 Sweden
Primary
Concomitant
Vomiting Other Serious 10 Female 5/18/2007 United States
Primary
Concomitant
Vomiting Hospitalization 15 Male 92 lb 5/18/2007 United States
Primary
Concomitant
Diarrhoea Other Serious 4/18/2007 90 Female 154 lb 5/26/2007 United Kingdom
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 5/12/2007 84 Female 5/28/2007 Consumer Brazil
Primary
Concomitant
Blood Urea Increased 1/31/2007 50 Female 4/10/2007 Physician United States
Primary
Concomitant
Hyperglycaemia Other Serious 3/22/2007 78 Male 145 lb 4/26/2007 United States
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 71 Female 6/26/2007 Physician Belgium
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 69 Female 6/26/2007 Italy
Primary
Secondary
Diarrhoea Other Serious 71 Female 7/9/2007 Belgium
Primary
Concomitant
Toxic Epidermal Necrolysis Death 69 Female 7/10/2007
Primary
Secondary
Toxic Epidermal Necrolysis Death 69 Female 7/12/2007
Primary
Secondary
Hypertension Life Threatening 1/8/2007 Female 7/16/2007 Physician Bulgaria
Primary
Concomitant
Skin Hypertrophy Other Serious 70 Male 6/29/2007 Other Health Professional Greece
Primary
Concomitant
Renal Failure Neonatal Hospitalization 0 Male 6 lb 6/29/2007 Other Health Professional India
Primary
Concomitant
Sarcoma Hospitalization 5/20/2003 Male 7/24/2007 United States
Primary
Concomitant
Pollakiuria Male 159 lb 7/25/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Hypertrophy Hospitalization 12/17/2006 Female 8/8/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Hospitalization 2/1/2007 78 Female 8/9/2007 Consumer Spain
Primary
Concomitant
Blood Pressure Decreased 5/5/2007 64 Male 8/3/2007 Consumer United States
Primary
Concomitant
Pneumonia Bacterial Hospitalization 12/17/2006 Female 8/15/2007 Physician United States
Primary
Concomitant
Hyperkalaemia Hospitalization 6/5/2006 92 Female 8/21/2007 Other Health Professional Sweden
Primary
Secondary
Concomitant
Swelling Other Serious 9/20/2006 63 Male 8/22/2007 Consumer United States
Primary
Concomitant
Tachycardia Hospitalization 78 Female 8/17/2007 Greece
Primary
Secondary
Injection Site Haemorrhage 4/30/2007 73 Male 7/11/2007 Consumer United States
Primary
Concomitant
Necrosis Death 1/1/2007 71 Female 8/30/2007 Belgium
Primary
Secondary
Concomitant
Atrial Fibrillation Disability 6/27/2007 71 Male 9/11/2007 United Kingdom
Primary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/14/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/27/2007 71 Male 194 lb 9/19/2007 Consumer United Kingdom
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 4/11/2007 Female 9/25/2007 Physician France
Primary
Concomitant
Atrial Fibrillation Disability 6/27/2007 71 Male 9/20/2007 United Kingdom
Primary
Concomitant
Back Pain 75 Male 9/20/2007 Consumer United States
Primary
Concomitant
Pancreatic Disorder Life Threatening 83 Male 216 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Electrocardiogram Abnormal Hospitalization 4/26/2007 73 Female 9/11/2007 Sweden
Primary
Secondary
Concomitant
Acute Myeloid Leukaemia Hospitalization 9/20/2007 54 Female 9/27/2007 Physician United States
Primary
Concomitant
Cardiac Disorder Death 10/6/2007 18 Male 93 lb 10/12/2007 Physician Romania
Primary
Concomitant
Cardiac Disorder Death 10/6/2007 18 Male 93 lb 10/12/2007 Physician Romania
Primary
Concomitant
Myocardial Infarction Other Serious 7/6/2003 Female 167 lb 10/16/2007 Lawyer United States
Primary
Secondary
Concomitant
Initial Insomnia 6/27/2007 93 Male 137 lb 10/5/2007 Consumer United States
Primary
Concomitant
Sick Sinus Syndrome Hospitalization 6/10/2007 72 Male 10/22/2007 Physician Sweden
Primary
Secondary
Concomitant

Drug Data