Didanosine combined with Tenofovir

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Tubular Necrosis Hospitalization 61 Male 1/11/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 10/19/2005 Male 130 lb 1/12/2006 Switzerland
Primary
Concomitant
Myopathy Other Serious 3/24/2005 38 Female 1/13/2006 Switzerland
Primary
Secondary
Renal Tubular Necrosis Hospitalization 44 Male 1/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/8/2001 Male 1/27/2006 Japan
Primary
Secondary
Concomitant
Corneal Deposits Other Serious 56 Male 1/30/2006 Physician Canada
Primary
Secondary
Hepatitis Toxic Other Serious 11/1/2005 36 Female 132 lb 2/1/2006 Physician Spain
Primary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 2/1/2006 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 2/2/2006 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 2/13/2006 Brazil
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 2/10/2006 Japan
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 1/1/2006 53 Female 2/13/2006 Physician Swaziland
Primary
Secondary
Concomitant
Interacting
Vertigo Disability 4/30/2004 40 Female 119 lb 2/14/2006 Physician Belgium
Primary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 2/14/2006 Brazil
Primary
Concomitant
Vertigo Disability 4/30/2004 40 Female 119 lb 2/20/2006 Physician Belgium
Primary
Concomitant
Viral Mutation Identified Other Serious Female 2/23/2006
Primary
Secondary
Weight Decreased Other Serious 9/1/2004 44 Male 2/24/2006 United States
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Pulmonary Hypertension Hospitalization 1/1/2003 39 Male 3/7/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2003 39 Male 3/13/2006 Physician France
Primary
Secondary
Concomitant
Cerebral Haemorrhage Hospitalization 2/26/2006 Male 3/14/2006 Spain
Primary
Concomitant
Liver Disorder Hospitalization 10/19/2005 Male 130 lb 3/16/2006 Switzerland
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2004 Male 3/20/2006 Physician Germany
Primary
Concomitant
Weight Decreased Hospitalization 7/1/2005 51 Female 108 lb 3/20/2006 Other Health Professional France
Primary
Secondary
Renal Failure Acute Life Threatening 6/9/2005 Male 170 lb 3/22/2006 United States
Primary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 4/6/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/24/2006 Male 115 lb 4/6/2006 Other Health Professional Ireland
Primary
Concomitant
Hydrocephalus Hospitalization 2/26/2006 Male 4/12/2006 Spain
Primary
Concomitant
Weight Decreased Hospitalization 10/19/2005 Male 130 lb 4/13/2006 Switzerland
Primary
Concomitant
Torsade De Pointes Hospitalization 1/1/2006 53 Female 4/17/2006 Physician Swaziland
Primary
Secondary
Concomitant
Interacting
Hepatitis Toxic Other Serious 11/1/2005 36 Female 132 lb 4/26/2006 Physician Spain
Primary
Concomitant
Hydrocephalus Hospitalization 2/26/2006 Male 5/11/2006 Spain
Primary
Concomitant
Melanocytic Naevus Hospitalization 10/19/2005 Male 130 lb 5/11/2006 Switzerland
Primary
Concomitant
Pneumonia Life Threatening 6/9/2005 Male 170 lb 5/12/2006 United States
Primary
Concomitant
Hydrocephalus Hospitalization 2/26/2006 Male 5/17/2006 Spain
Primary
Concomitant
Death Death 12/11/2004 Male 5/19/2006 United States
Primary
Concomitant
Tuberculosis Hospitalization 1/1/2004 Male 5/19/2006 Physician Germany
Primary
Concomitant
Viral Load Decreased Other Serious Male 5/19/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Insomnia Other Serious 3/4/2006 41 Male 146 lb 5/22/2006 Other Health Professional United Kingdom
Primary
Concomitant
Renal Failure Hospitalization 2/13/2006 56 Male 121 lb 5/26/2006 Other Health Professional France
Primary
Secondary
Intracranial Aneurysm Life Threatening 9/25/2005 Male 5/26/2006 United Kingdom
Primary
Concomitant
Medication Error 7/29/2005 45 Male 5/30/2006 Consumer United States
Primary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 6/1/2006 Portugal
Primary
Concomitant
Urine Sodium Increased Hospitalization 3/12/2004 26 Male 6/1/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/24/2006 Male 115 lb 6/2/2006 Other Health Professional Ireland
Primary
Concomitant
Metabolic Acidosis Hospitalization 10/14/2005 48 Female 6/16/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
Pancreatitis Other Serious 51 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 38 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 37 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 30 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 27 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 59 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Death Death 9/3/2004 Male 6/22/2006 United States
Primary
Concomitant
Tuberculosis Hospitalization 36 Male 7/5/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 12 Female 7/6/2006 United States
Primary
Secondary
Weight Decreased Other Serious Female 7/6/2006
Primary
Secondary
Pancreatitis Other Serious 51 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Hydrocephalus Hospitalization 2/26/2006 Male 7/12/2006 Spain
Primary
Concomitant
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
Renal Tubular Acidosis Other Serious 7/21/2006 United Kingdom
Primary
Secondary
Fanconi Syndrome Other Serious 7/21/2006 United Kingdom
Primary
Secondary
Renal Failure Other Serious 7/21/2006 United Kingdom
Primary
Secondary
Therapeutic Product Ineffective Hospitalization 1/1/2004 45 Male 7/21/2006 Other Health Professional France
Primary
Secondary
Death Death 2/18/2004 Male 7/24/2006 United States
Primary
Concomitant
Viral Load Decreased Other Serious Male 121 lb 7/31/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Intracranial Aneurysm Life Threatening 9/25/2005 Male 8/15/2006 United Kingdom
Primary
Concomitant
Weight Decreased Hospitalization 2/24/2006 Male 115 lb 8/17/2006 Other Health Professional Ireland
Primary
Concomitant
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 123 lb 8/21/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/17/2005 Male 130 lb 8/25/2006 Switzerland
Primary
Concomitant
Death Death 9/26/2004 32 Male 8/29/2006 United States
Primary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 60 Male 8/30/2006 Other Health Professional France
Primary
Secondary
Insomnia Other Serious 3/4/2006 41 Male 146 lb 8/31/2006 Other Health Professional United Kingdom
Primary
Concomitant
Sepsis Hospitalization 4/22/2006 Male 129 lb 8/31/2006 Argentina
Primary
Concomitant
Drug Ineffective Death 6/30/2004 38 Male 8/31/2006 United States
Primary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Osteoporosis Other Serious 2/1/2003 Male 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 2/24/2006 Male 115 lb 9/22/2006 Other Health Professional Ireland
Primary
Concomitant
Renal Impairment Required Intervention 9/23/2005 Male 4/28/2006 United States
Primary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Death Death 4/18/2005 Male 10/5/2006 United Kingdom
Primary
Concomitant
Hiv Infection Death Male 10/6/2006 Argentina
Primary
Concomitant
Death Death 12/1/2004 Male 10/6/2006 Italy
Primary
Concomitant
Retinal Detachment Hospitalization 9/10/2003 Female 10/6/2006 United States
Primary
Concomitant
Death Death 4/19/2004 Male 10/10/2006 Italy
Primary
Concomitant
Dysarthria Hospitalization 8/9/2006 45 Male Pharmacist United States
Primary
Concomitant
Hypoxia Hospitalization 5/2/2003 Male 10/12/2006 Germany
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Intracranial Aneurysm Life Threatening 9/25/2005 Male 10/13/2006 United Kingdom
Primary
Concomitant
Weight Decreased Other Serious Female 10/30/2006
Primary
Secondary
Weight Decreased Hospitalization 11/25/2002 Male 11/22/2006 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/12/2001 39 Male 11/29/2006 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 6/1/2001 42 Male 130 lb 12/1/2006 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 12/6/2006
Primary
Secondary
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 12/27/2006 Other Health Professional France
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 4/1/2002 Male 128 lb 1/17/2007 Other Health Professional France
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 8/1/2006 44 Male 1/19/2007 Physician United States
Primary
Concomitant
Renal Colic Other Serious 10/1/2005 38 Male 154 lb 1/22/2007 Physician France
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 2/5/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
Nephropathy Toxic Other Serious 58 Male 123 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 48 Male 132 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 10 Male 49 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 59 Male 104 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious Male 181 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 43 Male 86 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 51 Female 108 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 35 Female 121 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 41 Male 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 35 Female 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 41 Male 104 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 60 Male 154 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 58 Male 170 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Nephropathy Toxic Other Serious 47 Male 2/8/2007 Other Health Professional United States
Primary
Secondary
Hypokalaemia Other Serious 49 Male 128 lb 2/8/2007 Other Health Professional United States
Primary
Secondary
Subdural Haematoma Other Serious 7/30/2005 Male 4/5/2007 Physician Japan
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 4/16/2007 Physician United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 4/22/2006 Male 129 lb 4/24/2007 Argentina
Primary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 4/27/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening Male 5/3/2007 Pharmacist United Kingdom
Primary
Concomitant
Hypertriglyceridaemia Other Serious 8/1/2001 39 Male 5/1/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 63 Male 5/14/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 4/17/2005 Male 5/16/2007 Brazil
Primary
Concomitant
Weight Decreased Hospitalization 1/6/2006 Male 5/16/2007 Brazil
Primary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 5/17/2007 Physician Japan
Primary
Secondary
Concomitant
Subdural Haematoma Other Serious 7/30/2005 Male 5/23/2007 Physician Japan
Primary
Secondary
Concomitant
Eyelid Ptosis Hospitalization 12/1/2006 74 Female 5/25/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 6/6/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/13/2006 53 Female 6/7/2007 Swaziland
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 6/15/2007 Physician Japan
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 1/1/2006 53 Female 6/19/2007
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 4/1/2000 32 Female 97 lb 6/25/2007 Physician Belgium
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 6/27/2007 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 6/29/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 11/25/2002 Male 7/11/2007 Pharmacist Japan
Primary
Secondary
Concomitant
Weight Increased Hospitalization 14 Female 7/20/2007 Pharmacist United States
Primary
Secondary
Concomitant
Walking Disability Other Serious 2/23/1998 Male 7/31/2007 Physician Japan
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 7/1/2004 Male 8/2/2007 Physician Japan
Primary
Secondary
Concomitant

Drug Data