Didanosine combined with Tenofovir Disoproxil Fumarate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Subdural Haematoma Life Threatening 11/8/2005 43 Male 172 lb 4/14/2006 Physician United States
Primary
Secondary
Concomitant
Muscle Injury Hospitalization 1/1/2006 32 Male 183 lb 10/31/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/14/2006 44 Female 154 lb 2/13/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Varices Oesophageal Life Threatening 7/29/2006 Male 136 lb 2/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 3/16/2007 Physician Japan
Primary
Secondary
Concomitant
Meningitis Aseptic Hospitalization 8/1/2006 Male 156 lb 3/19/2007 Physician United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 3/20/2007 Physician United States
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 12 Male 3/22/2007
Primary
Secondary
Concomitant
Renal Impairment Hospitalization 7/1/2004 Male 3/23/2007 Physician Japan
Primary
Secondary
Concomitant
Visual Disturbance Life Threatening 3/16/1998 Male 3/24/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 7/29/2006 Male 136 lb 3/29/2007 Physician Brazil
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 3/29/2007 Physician United States
Primary
Secondary
Concomitant
Tuberculosis Life Threatening 32 Female 97 lb 6/15/2007 Belgium
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 2/23/2006 Male 167 lb 6/29/2007 Brazil
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/14/2006 44 Female 154 lb 7/5/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Renal Failure Acute Hospitalization 12/14/2006 44 Female 154 lb 7/5/2007 Other Health Professional Switzerland
Primary
Secondary
Concomitant
Abortion Induced Other Serious 3/25/2006 33 Female 7/23/2007 United States
Primary
Secondary
Trisomy 8 Other Serious Male 7 lb 7/27/2007 Other Health Professional United States
Primary
Secondary
Liver Disorder Hospitalization 9/27/2006 Male 8/22/2007 Japan
Primary
Secondary
Concomitant
Death Death 8/13/2007 Male 117 lb 8/23/2007 Physician Brazil
Primary
Secondary
Concomitant
Death Death 8/9/2007 Male 117 lb 8/27/2007 Physician Brazil
Primary
Secondary
Concomitant
Cardiogenic Shock Hospitalization 8/13/2007 Male 117 lb 9/5/2007 Physician Brazil
Primary
Secondary
Concomitant
Death Hospitalization 8/9/2007 Male 117 lb 9/5/2007 Brazil
Primary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 9/5/2007 Physician Japan
Primary
Secondary
Concomitant
Renal Impairment Other Serious 9/6/2007 Other Health Professional Switzerland
Primary
Secondary
Renal Failure Chronic Other Serious 5/25/2004 Male 9/7/2007 Physician Japan
Primary
Secondary
Concomitant
Hemiparesis Hospitalization 8/25/2007 Male 159 lb 9/10/2007 Physician Italy
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2005 9/11/2007 Other Health Professional Switzerland
Primary
Concomitant
Cd4 Lymphocytes Decreased Other Serious 5 37 lb 9/17/2007 Consumer United Kingdom
Primary
Secondary
Cardiogenic Shock Death 8/13/2007 Male 117 lb 9/18/2007 Brazil
Primary
Concomitant
Coronary Artery Disease Hospitalization 12/14/2006 Male 125 lb 9/24/2007 Physician United States
Primary
Secondary
Concomitant
Liver Disorder Hospitalization 10/17/2005 Male 130 lb 9/27/2007 Physician Switzerland
Primary
Secondary
Concomitant
Osteonecrosis Hospitalization 2/23/2006 Male 167 lb 9/27/2007 Brazil
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/27/2007 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/11/2007 10 Female 44 lb 10/15/2007 Pharmacist United States
Primary
Secondary
Renal Failure Acute Hospitalization 3/3/2007 Male 11/1/2007 United States
Primary
Secondary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 11/1/2007 Physician United States
Primary
Secondary
Concomitant
Visceral Leishmaniasis Other Serious 10/1/1996 46 Male 11/1/2007
Primary
Secondary
Concomitant
Umbilical Cord Abnormality Congenital Anomaly 9/5/2007 11/2/2007 United States
Primary
Secondary
Hypertriglyceridaemia Other Serious Male 11/16/2007 Other Health Professional Canada
Primary
Interacting
Type 2 Diabetes Mellitus Other Serious 1/1/1999 40 Male 11/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Renal Failure Chronic Other Serious 5/25/2004 Male 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Pneumonia Hospitalization 8/21/2002 Male 117 lb 11/20/2007 Physician Japan
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 11/22/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Hypertriglyceridaemia Other Serious 39 Male 11/30/2007 Other Health Professional Canada
Primary
Concomitant
Interacting
Premature Rupture Of Membranes Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Male 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Cardiomyopathy Other Serious Female 12/5/2007 Other Health Professional Netherlands
Primary
Secondary
Pancreatitis Hospitalization 4/10/2005 Male 192 lb 12/13/2007 Physician United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Other Serious Female 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Low Cardiac Output Syndrome Other Serious Male 2 lb 12/14/2007 Other Health Professional Netherlands
Primary
Secondary
Nervous System Disorder Hospitalization 8/25/2007 Male 159 lb 12/17/2007 Physician Italy
Primary
Concomitant
Nervous System Disorder Other Serious 3/1/2003 32 Male 12/19/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Prothrombin Level Decreased Life Threatening 9/6/2007 Male 1/24/2008 Physician Spain
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 3/1/2003 32 Male 2/4/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Homicide Death 6/30/2005 Male 2/6/2008 United States
Primary
Concomitant
Renal Failure Hospitalization 5/7/2004 Male 2/8/2008 Physician United States
Primary
Secondary
Concomitant
Pancreatitis Hospitalization 4/10/2005 Male 192 lb 2/12/2008 Physician United States
Primary
Secondary
Concomitant
Death Death 6/30/2005 Male 2/12/2008 United States
Primary
Concomitant
Lactic Acidosis Hospitalization 12/26/2007 68 Male 2/20/2008 Other Health Professional France
Primary
Secondary
Renal Failure Hospitalization 6/30/2007 Female 2/28/2008 United Kingdom
Primary
Concomitant
Viral Load Increased Other Serious 7/1/2003 Male 3/7/2008 Physician United States
Primary
Secondary
Concomitant
Retinopathy Other Serious 11/15/2007 Female 3/14/2008 Belgium
Primary
Concomitant
Osteonecrosis Hospitalization 2/23/2006 Male 167 lb 3/20/2008 Brazil
Primary
Secondary
Concomitant
Renal Failure Hospitalization 6/30/2007 Female 4/10/2008 United Kingdom
Primary
Concomitant
Renal Failure Death 4/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Tubular Disorder Hospitalization 12/1/2007 51 Male Physician France
Primary
Concomitant
Renal Tubular Necrosis Death 48 Male 4/11/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Umbilical Cord Abnormality Congenital Anomaly 9/5/2007 4/18/2008 United States
Primary
Secondary
Nephropathy Toxic Hospitalization 10 Female 44 lb 4/21/2008 United States
Primary
Secondary
Nephropathy Toxic Hospitalization 10 Female 44 lb 4/22/2008 United States
Primary
Secondary
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 4/25/2008 Physician Japan
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 4/28/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Nausea Other Serious Unknown 4/22/2008 Consumer United States
Primary
Secondary
Renal Tubular Necrosis Hospitalization 53 Male 4/29/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 4/29/2008
Primary
Secondary
Concomitant
Hepatic Steatosis Other Serious 46 Male 4/29/2008 United States
Primary
Secondary
Renal Failure Hospitalization 6/30/2007 Female 5/23/2008 United Kingdom
Primary
Concomitant
Pancytopenia Other Serious 5/26/1999 Male 6/3/2008 Physician United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Hospitalization 48 Male 6/10/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Headache Other Serious 11/21/2007 39 Female 99 lb 6/17/2008 Zimbabwe
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 6/19/2008 Physician Japan
Primary
Secondary
Concomitant
Headache Other Serious 11/21/2007 39 Female 99 lb 6/20/2008 Zimbabwe
Primary
Secondary
Concomitant
Weight Increased 43 Female 7/25/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Abortion Induced Other Serious 8/27/2008 33 Female 9/4/2008 Physician United States
Primary
Secondary
Lactic Acidosis Hospitalization 12/26/2007 68 Male 4/17/2009 Other Health Professional France
Primary
Secondary
Myocardial Infarction Other Serious 7/1/2002 48 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 7/1/2002 48 4/23/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Virologic Failure Hospitalization 7/1/2002 48 4/28/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Virologic Failure Life Threatening 7/1/2002 49 5/5/2009 United Kingdom
Primary
Secondary
Concomitant
Oesophageal Candidiasis Hospitalization 4/12/2005 Male 131 lb 5/26/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2001 7/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2001 50 Male 190 lb 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Treatment Failure Other Serious 8/3/2009 Other Health Professional Denmark
Primary
Secondary
Weight Decreased Hospitalization 39 Male 7/22/2009 United States
Primary
Secondary
Concomitant
Renal Failure Hospitalization 32 Male 7/22/2009 United States
Primary
Secondary
Concomitant
Nephrogenic Diabetes Insipidus Hospitalization 38 Male 7/22/2009 United States
Primary
Secondary
Concomitant
Pancreatitis Acute Other Serious 2/1/2002 Male 8/17/2009 Other Health Professional United Kingdom
Primary
Interacting
Pulmonary Hypertension Other Serious 40 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 55 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/4/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 57 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 55 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 48 Female 9/17/2009 Other Health Professional Spain
Primary
Secondary
Pulmonary Hypertension Other Serious 40 Male 9/17/2009 Other Health Professional Spain
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 54 Male 9/17/2009 Other Health Professional Canada
Primary
Secondary
Splenomegaly Other Serious 43 Female 9/11/2009
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/23/2009 Other Health Professional Canada
Primary
Secondary
Pneumocystis Jiroveci Pneumonia Other Serious 54 Unknown 9/15/2009 Canada
Primary
Secondary
Concomitant
Splenomegaly Other Serious 57 Male 9/21/2009 Spain
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 9/29/2009 Other Health Professional Canada
Primary
Secondary
Rapid Eye Movements Sleep Abnormal Other Serious 10/7/2009 Physician Australia
Primary
Secondary
Mitochondrial Toxicity Other Serious 54 Male 10/20/2009 Physician Canada
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 10/20/2009 Physician Canada
Primary
Secondary
Myocardial Infarction Other Serious 7/17/2003 Male 11/6/2009
Primary
Secondary
Concomitant
Weight Increased Other Serious 4/1/2001 11/16/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Myocardial Infarction Other Serious 7/17/2003 Male 11/16/2009 Other Health Professional Portugal
Primary
Secondary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 11/24/2009 Other Health Professional United States
Primary
Secondary
Hyperglycaemia Other Serious 44 Male 11/30/2009 Other Health Professional United States
Primary
Secondary
Interacting
Parkinsonism Other Serious 53 Male 11/24/2009 Australia
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/8/2010 Physician Canada
Primary
Secondary
Treatment Failure Required Intervention 11/1/2004 33 Male 150 lb 3/2/2010 Cote D'ivoire
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 3/11/2010 Physician Canada
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 3/26/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 3/31/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/1/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 4/28/2010 Physician Canada
Primary
Secondary
Osteonecrosis Hospitalization 33 Male 150 lb 4/29/2010 Other Health Professional Cote D'ivoire
Primary
Secondary
Renal Tubular Acidosis Life Threatening 4/12/2010 47 Male 106 lb 4/28/2010 Pharmacist United States
Primary
Concomitant
Progressive External Ophthalmoplegia Other Serious 52 5/4/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/4/2010 Other Health Professional United States
Primary
Secondary
Plagiocephaly Congenital Anomaly 4 5/6/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/7/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 5/7/2010 Consumer United States
Primary
Secondary
Ophthalmoplegia Other Serious 52 Male 5/11/2010 Consumer United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/12/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/13/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/14/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/17/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/18/2010 Other Health Professional United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/21/2010 Physician Canada
Primary
Secondary
Sinus Tachycardia Hospitalization 7/1/2003 41 5/17/2010 Portugal
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 5/28/2010 Physician United States
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 6/21/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/7/2010 Physician Canada
Primary
Secondary
Progressive External Ophthalmoplegia Other Serious 52 Male 7/8/2010 Physician Canada
Primary
Secondary

Drug Data