Didanosine combined with Stavudine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Abortion Induced Other Serious 5/1/2001 28 Female 1/5/2006 Japan
Primary
Concomitant
Pancreatitis Required Intervention 10/11/2005 Male 158 lb 12/28/2005 Pharmacist United States
Primary
Secondary
Zygomycosis Hospitalization 4/1/1998 39 Male 1/17/2006 Physician Italy
Primary
Secondary
Concomitant
Small For Dates Baby Other Serious 1/1/2002 2 lb 1/18/2006 Physician Spain
Primary
Secondary
Pancreatitis Hospitalization 1/23/2003 5/2/2003 Pharmacist United States
Primary
Secondary
Pleural Infection Hospitalization 8/14/1998 60 Male 452 lb 1/31/2006 United States
Primary
Secondary
Concomitant
Pleural Effusion Hospitalization 8/14/1998 60 Male 452 lb 2/2/2006 United States
Primary
Secondary
Concomitant
Post Procedural Diarrhoea Required Intervention 10/11/2005 Male 158 lb 1/18/2006 Pharmacist United States
Primary
Secondary
Concomitant
Premature Menopause Other Serious 2/1/1998 36 Female 2/6/2006 Consumer France
Primary
Secondary
Lactic Acidosis Other Serious 10 Female 2/8/2006 Other Health Professional India
Primary
Secondary
Kaposi's Sarcoma Aids Related Other Serious 2/21/2006
Primary
Secondary
Urethral Discharge Hospitalization 10/22/2003 22 Female 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9/1/2004 44 Male 2/24/2006 United States
Primary
Secondary
Rhabdomyolysis Other Serious 9/1/2003 Male 2/24/2006 Physician Japan
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/17/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Intra-uterine Death Other Serious 1/1/2002 32 Female 2/28/2006
Primary
Secondary
Concomitant
Pre-eclampsia Other Serious 1/1/2003 31 Female 2/28/2006
Primary
Secondary
Concomitant
Vomiting Other Serious 12/1/2001 Female 2/23/2006
Primary
Secondary
Concomitant
Therapy Non-responder Hospitalization 15 Male 2/28/2006 Physician United Kingdom
Primary
Secondary
Gynaecomastia Other Serious 15 Male 3/6/2006 Other Health Professional United Kingdom
Primary
Secondary
Pulmonary Hypertension Hospitalization 1/1/2003 39 Male 3/7/2006 Physician France
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 1/1/2003 39 Male 3/13/2006 Physician France
Primary
Secondary
Concomitant
Pancytopenia Other Serious 10/1/1999 Male 3/13/2006 Physician Japan
Primary
Secondary
Concomitant
Vomiting Hospitalization 2/1/2001 33 Male 3/14/2006
Primary
Secondary
Pulmonary Oedema Death Male 132 lb 3/15/2006 Physician Colombia
Primary
Concomitant
Immune Reconstitution Syndrome Other Serious 52 Male 3/17/2006 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious Male 3/17/2006 Spain
Primary
Secondary
Electrocardiogram Qt Prolonged Other Serious 62 Male 3/20/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Pneumonia Hospitalization 7/3/2002 Male 3/20/2006 Physician Japan
Primary
Secondary
Concomitant
Blood Hiv Rna Increased Other Serious 41 Male 3/27/2006
Primary
Secondary
Weight Decreased Other Serious Male 3/17/2006 Physician Spain
Primary
Secondary
Pyrexia Hospitalization 5/2/2003 36 Male 4/7/2006 Physician Japan
Primary
Secondary
Concomitant
Immune Reconstitution Syndrome Hospitalization 52 Male 4/10/2006 Other Health Professional United States
Primary
Secondary
Pneumonia Hospitalization 7/3/2002 Male 4/13/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Hospitalization 5/2/2003 36 Male 4/20/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia 4/30/1998 41 Male 4/21/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperbilirubinaemia Hospitalization 10/22/2003 16 Female 115 lb 4/24/2006 Consumer United States
Primary
Secondary
Concomitant
Lactic Acidosis Required Intervention 3/29/2006 69 Male 127 lb 3/29/2006 Pharmacist United States
Primary
Secondary
Immune Reconstitution Syndrome Other Serious 58 Male 5/8/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pulmonary Oedema Death 12/1/2005 33 Male 132 lb 5/8/2006 Physician Colombia
Primary
Concomitant
Renal Failure Hospitalization 8/9/2004 Male 5/18/2006 United States
Primary
Concomitant
Portal Vein Thrombosis Other Serious 33 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 52 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 56 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 36 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 57 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 45 Female 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 54 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 37 Male 5/26/2006 Other Health Professional Spain
Primary
Secondary
Hepatitis C Other Serious Male 6/2/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Infection Other Serious 45 Female 5/26/2006 Poland
Primary
Secondary
Thrombocytopenia Death 8/9/2004 Male 6/14/2006 United States
Primary
Concomitant
Pancreatitis Other Serious 45 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 28 Female 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 38 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 37 Male 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 66 Female 6/19/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 27 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 59 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 66 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 29 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Sepsis Other Serious 46 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Pancreatitis Other Serious 51 Male 6/20/2006 Other Health Professional Denmark
Primary
Secondary
Lung Infection Hospitalization 2/13/2006 Male 6/23/2006 Ireland
Primary
Concomitant
Pancytopenia Other Serious 5/26/1999 41 Male 7/5/2006 Physician United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 7/5/1999 Male 7/6/2006 Physician Japan
Primary
Secondary
Concomitant
Liver Disorder Other Serious 49 Female 7/6/2006
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Hyperlipidaemia Other Serious 9/27/2001 Male 7/7/2006 Physician Japan
Primary
Secondary
Concomitant
Lung Infection Hospitalization 2/13/2006 Male 7/7/2006 Ireland
Primary
Concomitant
Hepatic Fibrosis Other Serious 56 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 33 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 28 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 27 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 45 Female 7/10/2006
Primary
Secondary
Hepatic Fibrosis Other Serious 54 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 37 Male 7/10/2006
Primary
Secondary
Hepatic Fibrosis Other Serious 57 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 36 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 52 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 51 Male 7/10/2006
Primary
Secondary
Sepsis Other Serious 46 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Pancreatitis Other Serious 51 Male 7/11/2006 Other Health Professional France
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 7/11/2006
Primary
Secondary
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 28 Male 7/10/2006
Primary
Secondary
White Blood Cell Count Decreased Other Serious 12/4/1998 Male 7/19/2006 Physician Japan
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 4/27/2006 50 Male 7/31/2006 Other Health Professional South Africa
Primary
Secondary
Concomitant
Anorectal Disorder Other Serious 7/1/2005 Male 8/11/2006 Physician Japan
Primary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/11/2006 Physician Japan
Primary
Secondary
Concomitant
Pyrexia Other Serious 7/1/2005 Male 8/14/2006 Physician United States
Primary
Secondary
Concomitant
Patella Fracture Other Serious 3/31/2003 Male 8/18/2006 Physician Japan
Primary
Secondary
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/21/2002 Male 117 lb 8/22/2006 Physician Japan
Primary
Secondary
Concomitant
Shock Other Serious 30 Female 8/23/2006 Other Health Professional Portugal
Primary
Secondary
Pruritus Other Serious 41 Male 8/23/2006
Primary
Secondary
Mitochondrial Toxicity Other Serious 6/1/1998 36 Female 8/18/2006 Physician France
Primary
Concomitant
Rib Fracture Other Serious 1/1/2001 57 Male 8/25/2006 Physician United States
Primary
Secondary
Myocarditis Hospitalization 7/1/2002 Male 8/25/2006 Physician Japan
Primary
Secondary
Concomitant
Hypospadias Congenital Anomaly Male 8/22/2006 Other Health Professional United States
Primary
Secondary
Jaundice Other Serious 9/1/2000 58 Male 8/28/2006
Primary
Secondary
Therapeutic Response Decreased Other Serious 26 Male 8/21/2006 Switzerland
Primary
Secondary
Concomitant
Hepatitis B Dna Assay Positive Other Serious 52 Male 8/29/2006
Primary
Secondary
Concomitant
Vomiting Death 47 Female 8/29/2006
Primary
Secondary
Mitochondrial Dna Depletion Hospitalization 47 Female 8/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Progressive Multifocal Leukoencephalopathy Hospitalization 60 Male 8/30/2006 Other Health Professional France
Primary
Secondary
Metabolic Disorder Hospitalization 47 Female 8/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Drug Resistance Other Serious 6/28/2006 20 Male 8/31/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rhabdomyolysis Other Serious 9/1/2003 Male 9/1/2006 Physician Japan
Primary
Secondary
Concomitant
Metabolic Disorder Hospitalization 47 Female 9/6/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Sudden Hearing Loss Other Serious 26 Male 8/30/2006 Switzerland
Primary
Secondary
Concomitant
Death Death 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Neuropathy Peripheral Other Serious 9/6/2006
Primary
Secondary
Viral Mutation Identified Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Viral Mutation Identified Other Serious 9/6/2006
Primary
Secondary
Osteonecrosis Other Serious 1/1/2001 Male 9/8/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Von Willebrand's Disease Other Serious 38 Female 9/8/2006 Belgium
Primary
Concomitant
Sick Sinus Syndrome Other Serious 10/1/1999 Male 9/8/2006 Physician Japan
Primary
Secondary
Concomitant
Nervous System Disorder Other Serious 26 Male 9/6/2006 Switzerland
Primary
Concomitant
Toxic Skin Eruption Disability 8/6/2006 Male 9/13/2006 Other Health Professional Portugal
Primary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Vasodilatation Life Threatening 10/24/2001 Male 9/13/2006 Physician Japan
Primary
Secondary
Concomitant
Toxic Skin Eruption Disability 8/6/2006 Male 9/14/2006 Other Health Professional Portugal
Primary
Concomitant
Walking Disability Other Serious 10/14/1996 Male 9/14/2006 Physician Japan
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/14/2006 Japan
Primary
Secondary
Concomitant
Therapy Non-responder Required Intervention 57 Male 9/8/2006 United States
Primary
Secondary
Concomitant
Pulmonary Hypertension Other Serious 4/1/2003 39 Male 9/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Lipohypertrophy Other Serious 9/26/2002 Male 9/25/2006 Japan
Primary
Secondary
Concomitant
Weight Decreased Other Serious 9 Female 10/6/2006
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Male 10/6/2006 United States
Primary
Concomitant
Splenomegaly Hospitalization 3/21/2003 Male 10/6/2006 Spain
Primary
Concomitant
Hepatic Fibrosis Other Serious 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Hepatic Fibrosis Other Serious 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Hepatic Fibrosis Other Serious 10/10/2006 Other Health Professional United Kingdom
Primary
Secondary
Death Death 4/19/2004 Male 10/10/2006 Italy
Primary
Concomitant
Renal Failure Death 8/9/2004 Male 10/10/2006 United States
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Viral Load Increased Other Serious 7/1/2006 Female 10/20/2006 Consumer United States
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2002 57 Male 10/26/2006 Other Health Professional Italy
Primary
Secondary
Vomiting Life Threatening 1/1/2000 Female 10/26/2006
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 36 Male 10/27/2006 Canada
Primary
Secondary
Concomitant
Interacting
Hyperlipidaemia Other Serious 7/1/2002 Male 11/1/2006 Physician Japan
Primary
Secondary
Concomitant
Viral Load Increased Other Serious 7/1/2006 Female 11/3/2006 Physician United States
Primary
Concomitant

Drug Data