Didanosine combined with Nevirapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Proteinuria Other Serious 1/1/2003 33 Female 1/18/2006 Physician Spain
Primary
Secondary
Viral Mutation Identified Other Serious 1/18/2006
Primary
Secondary
Small For Dates Baby Other Serious 1/1/2002 2 lb 1/18/2006 Physician Spain
Primary
Secondary
Varices Oesophageal Other Serious 5/19/2005 41 Female 134 lb 2/6/2006 France
Primary
Secondary
Hypokalaemia Life Threatening 3/5/2005 Male 2/8/2006 Zimbabwe
Primary
Secondary
Concomitant
Lactic Acidosis Other Serious 10 Female 2/8/2006 Other Health Professional India
Primary
Secondary
Oesophageal Varices Haemorrhage Death 36 Male 2/14/2006
Primary
Secondary
Kaposi's Sarcoma Aids Related Other Serious 2/21/2006
Primary
Secondary
Intra-uterine Death Other Serious 32 Female 2/13/2006 Spain
Primary
Secondary
Viral Mutation Identified Other Serious Female 2/23/2006
Primary
Secondary
Intra-uterine Death Other Serious 1/1/2002 32 Female 2/28/2006
Primary
Secondary
Concomitant
Pre-eclampsia Other Serious 1/1/2003 33 Female 2/28/2006
Primary
Secondary
Pre-eclampsia Other Serious 1/1/2003 31 Female 2/28/2006
Primary
Secondary
Concomitant
Gamma-glutamyltransferase Abnormal Other Serious 10/14/2005 27 Female 3/10/2006 Consumer South Africa
Primary
Secondary
Trisomy 21 Other Serious 3/16/2006 Other Health Professional United States
Primary
Concomitant
Trisomy 21 Congenital Anomaly 1/1/2005 3/15/2006 Other Health Professional United States
Primary
Secondary
Blood Hiv Rna Increased Other Serious 41 Male 3/27/2006
Primary
Secondary
Gamma-glutamyltransferase Increased Other Serious 1/27/2006 48 Female 4/10/2006 Physician Botswana
Primary
Secondary
Renal Failure Acute Hospitalization 6/12/2003 Male 195 lb 4/12/2006 Canada
Primary
Secondary
Concomitant
Pancytopenia Hospitalization 2/3/2006 45 Female 4/28/2006 Other Health Professional South Africa
Primary
Secondary
Portal Vein Thrombosis Other Serious 33 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 52 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 56 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 36 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 57 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 45 Female 5/25/2006 Other Health Professional Spain
Primary
Secondary
Hepatocellular Damage Other Serious 54 Male 5/25/2006 Other Health Professional Spain
Primary
Secondary
Portal Vein Thrombosis Other Serious 37 Male 5/26/2006 Other Health Professional Spain
Primary
Secondary
Intracranial Aneurysm Life Threatening 9/25/2005 Male 5/26/2006 United Kingdom
Primary
Concomitant
Liver Disorder Other Serious 49 Female 7/6/2006
Primary
Secondary
Weight Decreased Other Serious Female 7/6/2006
Primary
Secondary
Hepatic Fibrosis Other Serious 56 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 33 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 28 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 27 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 45 Female 7/10/2006
Primary
Secondary
Hepatic Fibrosis Other Serious 54 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 37 Male 7/10/2006
Primary
Secondary
Hepatic Fibrosis Other Serious 57 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 36 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 52 Male 7/10/2006
Primary
Secondary
Liver Disorder Other Serious 51 Male 7/10/2006
Primary
Secondary
Portal Vein Thrombosis Other Serious 43 Male 7/11/2006
Primary
Secondary
Trisomy 21 Congenital Anomaly 1/24/2006 Male 7/11/2006 Other Health Professional United States
Primary
Secondary
Trisomy 21 Other Serious 32 Female 7/13/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 33 Female 7/14/2006 Germany
Primary
Secondary
Concomitant
Liver Function Test Abnormal Other Serious 28 Male 7/10/2006
Primary
Secondary
Trisomy 21 Congenital Anomaly 1/1/2005 Male 7/21/2006 Other Health Professional United States
Primary
Secondary
Weight Decreased Other Serious Female 5/11/2006 Physician United States
Primary
Concomitant
Intracranial Aneurysm Life Threatening 9/25/2005 Male 8/15/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Hospitalization 31 Female 8/18/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Decreased Other Serious 33 Female 8/21/2006 Germany
Primary
Secondary
Concomitant
Pruritus Other Serious 41 Male 8/23/2006
Primary
Secondary
Jaundice Other Serious 9/1/2000 58 Male 8/28/2006
Primary
Secondary
Therapeutic Response Decreased Other Serious 26 Male 8/21/2006 Switzerland
Primary
Secondary
Concomitant
Hepatitis B Dna Assay Positive Other Serious 52 Male 8/29/2006
Primary
Secondary
Concomitant
Vomiting Death 47 Female 8/29/2006
Primary
Secondary
Mitochondrial Dna Depletion Hospitalization 47 Female 8/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Metabolic Disorder Hospitalization 47 Female 8/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Suicidal Ideation Hospitalization 8/30/1997 38 Male 9/1/2006 Other Health Professional United Kingdom
Primary
Concomitant
Interacting
Suicidal Ideation Hospitalization 8/30/1997 Male 143 lb 9/1/2006 United Kingdom
Primary
Concomitant
Interacting
Shock Other Serious 47 Female 8/29/2006 Canada
Primary
Secondary
Concomitant
Metabolic Disorder Hospitalization 47 Female 9/6/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Sudden Hearing Loss Other Serious 26 Male 8/30/2006 Switzerland
Primary
Secondary
Concomitant
Death Death 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Neuropathy Peripheral Other Serious 9/6/2006
Primary
Secondary
Viral Mutation Identified Other Serious 9/6/2006
Primary
Secondary
Drug Resistance Other Serious 9/6/2006
Primary
Secondary
Viral Mutation Identified Other Serious 9/6/2006
Primary
Secondary
Nervous System Disorder Other Serious 26 Male 9/6/2006 Switzerland
Primary
Concomitant
Rib Fracture Other Serious 1/1/1996 Male 9/13/2006
Primary
Secondary
Concomitant
Sudden Hearing Loss Other Serious 26 Male 9/15/2006
Primary
Secondary
Concomitant
Therapy Non-responder Required Intervention 57 Male 9/8/2006 United States
Primary
Secondary
Concomitant
Lipodystrophy Acquired Other Serious 58 Male 9/19/2006
Primary
Secondary
Treatment Noncompliance Required Intervention 5/17/2006 67 Male 201 lb 5/23/2006 Pharmacist United States
Primary
Concomitant
Weight Decreased Other Serious 9 Female 10/6/2006
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization Male 10/6/2006 United States
Primary
Concomitant
Death Death 6/30/2005 Male 10/12/2006 United States
Primary
Concomitant
Intracranial Aneurysm Life Threatening 9/25/2005 Male 10/13/2006 United Kingdom
Primary
Concomitant
Bladder Cancer Other Serious 1/1/2002 57 Male 10/26/2006 Other Health Professional Italy
Primary
Secondary
Vomiting Life Threatening 1/1/2000 Female 10/26/2006
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 10/30/2006
Primary
Secondary
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Weight Decreased Death 2/15/2001 Male 11/13/2006 Physician Japan
Primary
Secondary
Concomitant
Prostate Cancer Other Serious 10/1/2002 58 Male 11/29/2006
Primary
Secondary
Drug Effect Decreased Disability 9/1/2003 64 Male 11/29/2006
Primary
Secondary
Speech Disorder Developmental Hospitalization 4/1/1999 Male 6 lb 12/1/2006 Consumer France
Primary
Secondary
Concomitant
Speech Disorder Developmental Hospitalization 12/1/2000 4 Male 12/1/2006 Consumer France
Primary
Secondary
Neutropenia Hospitalization 1/31/2001 Female 6 lb 12/1/2006 Other Health Professional France
Primary
Secondary
Small For Dates Baby Disability 7/12/1999 Female 5 lb 12/4/2006 Consumer France
Primary
Secondary
Tremor Hospitalization 3/5/2001 0 Male 6 lb 12/4/2006 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious Female 12/6/2006
Primary
Secondary
Uterine Cyst Hospitalization Female 7 lb 12/12/2006 Consumer France
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 12/15/2006
Primary
Secondary
Prostate Cancer Other Serious 6/1/2000 59 Male 12/19/2006 Other Health Professional United Kingdom
Primary
Secondary
Nonspecific Reaction Hospitalization 7/28/1999 0 Female 12/18/2006 Other Health Professional France
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 10/6/2006 Male 1/31/2007 Physician Thailand
Primary
Secondary
White Blood Cell Count Decreased Life Threatening 10/6/2006 Male 2/6/2007 Physician Thailand
Primary
Secondary
Trisomy 21 Life Threatening 10/6/2006 Male 2/6/2007 Physician Thailand
Primary
Secondary
Nodular Regenerative Hyperplasia Hospitalization 39 Male 2/7/2007 Physician France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 2/22/2007 Physician Japan
Primary
Secondary
Concomitant
Varices Oesophageal Hospitalization 2/23/2007
Primary
Secondary
Varices Oesophageal Hospitalization 2/23/2007
Primary
Secondary
Varices Oesophageal Hospitalization Male 2/23/2007
Primary
Secondary
Small For Dates Baby Other Serious 10/30/2006 0 Female 5 lb 3/5/2007 Physician Thailand
Primary
Secondary
Concomitant
Vomiting Hospitalization 31 Female 3/6/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Acute Hepatic Failure Hospitalization 1/13/2005 Female 3/13/2007 Zimbabwe
Primary
Secondary
Concomitant
Hepatic Failure Life Threatening 3/5/2005 Male 3/14/2007 Zimbabwe
Primary
Secondary
Concomitant
Drug Ineffective Hospitalization 12 Male 3/22/2007
Primary
Secondary
Concomitant
Lymphadenopathy Other Serious 3/30/2007 Other Health Professional United Kingdom
Primary
Secondary
Lymphadenopathy Other Serious 4/19/2007
Primary
Secondary
Hiv Test Positive Other Serious 4/19/2007
Primary
Secondary
Oligohydramnios Other Serious Female 4/19/2007
Primary
Secondary
Lymphadenopathy Other Serious 4/20/2007
Primary
Secondary
Oligohydramnios Other Serious Female 4/23/2007
Primary
Secondary
Hiv Test Positive Other Serious 4/23/2007
Primary
Secondary
Lymphadenopathy Other Serious 4/30/2007
Primary
Secondary
Oligohydramnios Other Serious Female 4/30/2007
Primary
Secondary
Hiv Test Positive Other Serious 4/30/2007
Primary
Secondary
Treatment Noncompliance Other Serious 5/3/2007
Primary
Secondary
Hypertriglyceridaemia Other Serious 8/1/2001 39 Male 5/1/2007 Other Health Professional Canada
Primary
Secondary
Concomitant
Lung Infection Hospitalization 5/15/2007
Primary
Secondary
Herpes Zoster Hospitalization 5/15/2007
Primary
Secondary
Unevaluable Event Hospitalization 9/9/1999 Female 7 lb 6/5/2007 Other Health Professional United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/7/2007 Physician Japan
Primary
Secondary
Concomitant
Talipes Other Serious 9/9/1999 Female 7 lb 6/8/2007 Consumer France
Primary
Secondary
Concomitant
Urticaria Other Serious 4/21/2007 Male 6/12/2007 Physician France
Primary
Concomitant
Interacting
White Blood Cell Count Decreased Other Serious 9/10/2001 Male 6/14/2007 Physician Japan
Primary
Secondary
Concomitant
Stillbirth Death 6/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Torsade De Pointes Hospitalization 1/1/2006 53 Female 6/19/2007
Primary
Secondary
Concomitant
Pregnancy Other Serious 7 lb 7/13/2007 Other Health Professional United Kingdom
Primary
Secondary
White Blood Cell Count Decreased Other Serious 11/10/1999 Male 8/10/2007 Physician Japan
Primary
Secondary
Concomitant
Nodular Regenerative Hyperplasia Other Serious Female 8/16/2007 Other Health Professional France
Primary
Secondary
Vascular Purpura Other Serious 49 Female 8/29/2007 France
Primary
Secondary
Concomitant
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Concomitant
Drug Resistance Other Serious Female 9/10/2007 Czech Republic
Primary
Secondary
Drug Resistance Other Serious Male 9/10/2007 Czech Republic
Primary
Secondary
Weight Decreased Hospitalization 1/1/2005 9/11/2007 Other Health Professional Switzerland
Primary
Concomitant
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/13/2007 Other Health Professional United States
Primary
Secondary
Pregnancy Congenital Anomaly Female 2 lb 9/14/2007 Other Health Professional United States
Primary
Secondary
Joint Dislocation Congenital Anomaly Female 2 lb 9/17/2007 United States
Primary
Secondary

Drug Data