Diclofenac combined with Leflunomide

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Renal Failure Hospitalization 2/1/2003 59 Male 1/17/2006 Other Health Professional France
Primary
Secondary
Concomitant
Movement Disorder Hospitalization 11/26/2005 Female 2/10/2006 Physician United Kingdom
Primary
Secondary
Concomitant
Osteitis Hospitalization 8/23/2004 Female 163 lb 2/15/2006 Netherlands
Primary
Concomitant
Pulmonary Function Test Decreased Hospitalization 1/1/2004 75 Male 3/11/2006 United Kingdom
Primary
Concomitant
Osteitis Hospitalization 8/23/2004 Female 163 lb 4/11/2006 Netherlands
Primary
Concomitant
Toe Amputation Hospitalization 8/23/2004 Female 163 lb 4/11/2006 Netherlands
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2006 Female 163 lb 4/12/2006 Netherlands
Primary
Concomitant
Pulmonary Embolism Other Serious 11/19/2005 Female 7/11/2006 France
Primary
Concomitant
Pruritus Other Serious 50 Female 7/19/2006 Physician Brazil
Primary
Concomitant
Streptococcal Infection Life Threatening 7/8/2006 69 Female 7/21/2006 Physician Spain
Primary
Secondary
Concomitant
B-cell Lymphoma Stage Ii Other Serious 4/13/2006 68 Male 132 lb 7/31/2006 Other Health Professional Germany
Primary
Concomitant
Shock Haemorrhagic Other Serious 5/1/2005 Female 104 lb 8/10/2006 Physician Germany
Primary
Secondary
Concomitant
Atelectasis Hospitalization 6/9/2006 59 Female 185 lb 8/30/2006 Other Health Professional Canada
Primary
Secondary
Concomitant
Pruritus Other Serious 50 Female 9/1/2006 Physician Brazil
Primary
Secondary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Pneumonitis Hospitalization 1/1/2004 75 Male 9/12/2006 United Kingdom
Primary
Concomitant
Infection Hospitalization 9/6/2006 Female 10/13/2006 Consumer United Kingdom
Primary
Concomitant
Skin Disorder Hospitalization 1/1/2006 Female 163 lb 10/18/2006 Netherlands
Primary
Concomitant
Vulvar Dysplasia Other Serious 4/1/2006 51 Female 11/8/2006 Physician Turkey
Primary
Concomitant
Squamous Cell Carcinoma Other Serious 4/12/2006 Male 161 lb 4/26/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tongue Blistering Other Serious Female 6/4/2007 Physician United Kingdom
Primary
Concomitant
Throat Irritation Hospitalization 12/1/2005 Male 7/11/2007 Belgium
Primary
Secondary
Concomitant
Joint Dislocation Hospitalization 7/9/2007 Female 146 lb 7/19/2007 United Kingdom
Primary
Concomitant
Joint Swelling Hospitalization 5/12/2006 Female 119 lb 7/20/2007 Other Health Professional United Kingdom
Primary
Concomitant
Lower Respiratory Tract Infection Other Serious 5/6/2007 Male 154 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Death Other Serious Male 121 lb 12/3/2007 Other Health Professional United Kingdom
Primary
Concomitant
Testis Cancer Other Serious 10/27/2005 Male 150 lb 12/17/2007 Other Health Professional United Kingdom
Primary
Concomitant
Testis Cancer Other Serious 10/27/2005 Male 150 lb 12/17/2007 United Kingdom
Primary
Concomitant
Osteonecrosis Other Serious 6/1/2004 45 Female 152 lb 11/28/2007 Other Health Professional United States
Primary
Concomitant
Testis Cancer Other Serious 10/27/2005 Male 150 lb 12/20/2007 United Kingdom
Primary
Concomitant
Pain In Extremity Hospitalization 5/6/2007 55 Male 12/21/2007 Physician United Kingdom
Primary
Concomitant
Prostate Cancer Stage Ii Hospitalization 11/13/2006 Male 183 lb 2/8/2008 Physician Germany
Primary
Secondary
Concomitant
Pain 1/18/2008 Female 156 lb 3/15/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 7/4/2007 Female 5/2/2008 Belgium
Primary
Concomitant
Urinary Retention Hospitalization 8/1/2007 Male 181 lb 5/6/2008 Brazil
Primary
Concomitant
Interacting
Psoriatic Arthropathy 8/1/2006 32 Male 154 lb 6/13/2008 Physician United States
Primary
Concomitant
Breast Cancer Other Serious 8/12/2007 Female 187 lb 7/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 8/12/2007 Female 187 lb 7/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 8/12/2007 Female 187 lb 9/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Breast Cancer Other Serious 8/12/2007 Female 187 lb 9/11/2008 Other Health Professional United Kingdom
Primary
Concomitant
Psoriatic Arthropathy 8/1/2006 Male 154 lb 9/12/2008 Physician United States
Primary
Concomitant
Road Traffic Accident 11/28/2007 Female 180 lb 9/13/2008 Consumer United States
Primary
Concomitant
Staphylococcal Infection Hospitalization 10/23/2007 44 Male 9/25/2008 Physician United States
Primary
Concomitant
Urinary Retention Hospitalization 8/1/2007 Male 181 lb 10/2/2008 Brazil
Primary
Concomitant
Interacting
Respiratory Disorder Hospitalization 12/19/2007 Female 137 lb 10/17/2008 United Kingdom
Primary
Concomitant
Respiratory Failure Death 6/11/2008 Male 150 lb 10/17/2008 United Kingdom
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 10/20/2008 Physician Colombia
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 10/22/2008 Physician Colombia
Primary
Concomitant
Polydipsia Other Serious 6/1/2008 58 Female 115 lb 10/31/2008 Physician Colombia
Primary
Concomitant
Thrombosis Hospitalization 2/16/2008 Male 3/9/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pneumonia Other Serious 1/1/2008 Female 128 lb 3/13/2009 Other Health Professional United Kingdom
Primary
Concomitant
Injection Site Swelling Other Serious 12/1/2008 Female 3/20/2009 Other Health Professional United Kingdom
Primary
Concomitant
Myocardial Infarction Death 3/1/2009 112 lb 4/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Nephritis Other Serious 9/1/2008 61 Female 110 lb 6/19/2009 Physician United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 61 Female 110 lb 6/29/2009 Physician United Kingdom
Primary
Secondary
Concomitant
Pain Death 58 Female 7/30/2009 Lawyer United States
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/20/2009
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/21/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/24/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/26/2009 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 8/24/2009 Other Health Professional United Kingdom
Primary
Concomitant
Tubulointerstitial Nephritis Other Serious 9/1/2008 60 Female 117 lb 8/28/2009 Other Health Professional United Arab Emirates
Primary
Secondary
Alopecia Totalis Other Serious 6/1/2009 39 Female 154 lb 11/19/2009 Other Health Professional United Kingdom
Primary
Concomitant
Staphylococcal Infection Other Serious 4/26/2002 67 Female 12/8/2009 Physician Spain
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 7/1/2009 57 Female 178 lb 12/9/2009 Other Health Professional United States
Primary
Concomitant
Vomiting 1/1/2002 Female 12/9/2009 Physician United States
Primary
Concomitant
Pulmonary Hypertension Hospitalization 12/29/2009 Male 209 lb 2/5/2010 Consumer United Kingdom
Primary
Concomitant
Breast Cancer In Situ Life Threatening 9/1/2009 60 Female 150 lb 3/3/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pulmonary Sarcoidosis Other Serious 45 Male 4/2/2010
Primary
Secondary
Concomitant
Myocardial Infarction Hospitalization 3/16/2008 73 Female 4/19/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Cholecystitis Hospitalization 11/9/2008 74 Female 4/20/2010 Physician United Kingdom
Primary
Secondary
Concomitant
Sepsis Life Threatening 6/1/2009 58 Female 193 lb 5/11/2010 Physician Argentina
Primary
Concomitant
Sepsis Hospitalization 9/1/2009 61 Female 5/13/2010 Germany
Primary
Secondary
Concomitant
Sensation Of Heaviness Other Serious 6/1/2010 53 Female 170 lb 8/10/2010 Consumer United States
Primary
Concomitant
Sinusitis Other Serious 8/1/2009 51 Female 9/10/2010 Other Health Professional South Africa
Primary
Concomitant
Pneumonia Other Serious 1/1/2008 72 Female 128 lb 9/14/2010 Other Health Professional United Kingdom
Primary
Concomitant
Post Procedural Infection Hospitalization 6/3/2007 69 Female 146 lb 9/28/2010 Other Health Professional United Kingdom
Primary
Concomitant
Sensation Of Heaviness Other Serious 6/1/2010 53 Female 170 lb 12/10/2010 Physician United States
Primary
Concomitant
Vomiting Hospitalization 10/26/2010 60 Male 130 lb 12/10/2010 Physician Germany
Primary
Concomitant
Synovitis Other Serious Female 12/23/2010 Consumer United Kingdom
Primary
Concomitant
Rheumatoid Arthritis 6/26/2010 12/23/2010 Physician United States
Primary
Concomitant
Rash Pustular 10/18/2010 60 Female 135 lb 1/30/2011 Consumer United States
Primary
Concomitant
Fall Hospitalization 7/24/2010 69 Female 110 lb 1/30/2011 Physician United States
Primary
Concomitant
Injection Site Pain 1/1/2007 41 Female 135 lb 1/30/2011 Consumer United States
Primary
Secondary
Concomitant
Injection Site Haematoma 9/28/2010 73 Female 110 lb 1/30/2011 Consumer United States
Primary
Concomitant
Rotator Cuff Syndrome Other Serious 12/1/2009 60 Female 153 lb 1/30/2011 Physician United States
Primary
Concomitant
Subcutaneous Abscess Hospitalization 1/1/2010 64 Female 2/11/2011 Other Health Professional Germany
Primary
Concomitant
Prostate Cancer Hospitalization 1/1/2009 58 Male 2/15/2011 Other Health Professional United Kingdom
Primary
Concomitant
Blood Creatine Increased Other Serious 9/1/2008 60 Female 117 lb 2/22/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Contusion Hospitalization 10/1/2010 48 Female 176 lb 3/30/2011 Other Health Professional Australia
Primary
Concomitant
Diarrhoea Death 6/1/2009 58 Female 193 lb 4/5/2011 Physician Argentina
Primary
Concomitant
Renal Failure Acute Hospitalization 2/5/2011 53 Male 4/7/2011 Physician United Kingdom
Primary
Concomitant
Viral Infection Hospitalization 2/21/2011 52 Female 141 lb 4/13/2011 Physician United Kingdom
Primary
Concomitant
Vision Blurred Other Serious 56 Female 187 lb 7/21/2011 Other Health Professional Poland
Primary
Concomitant
Cervical Dysplasia Other Serious 20 Female 9/26/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Rheumatoid Nodule Hospitalization 9/9/2010 75 Female 126 lb 1/4/2012 Physician Germany
Primary
Concomitant
Maternal Exposure During Pregnancy Other Serious 9/30/2011 37 Female 1/24/2012 Physician Argentina
Primary
Concomitant
Rheumatoid Arthritis 4/1/2011 59 Female 165 lb 1/28/2012 Consumer United States
Primary
Concomitant
Injection Site Extravasation 1/1/2009 76 Male 1/27/2012 Consumer United States
Primary
Concomitant
Urinary Tract Infection 4/1/2011 58 Female 200 lb 1/28/2012 Consumer United States
Primary
Concomitant
Oropharyngeal Pain 10/1/2011 56 Male 1/29/2012 Consumer United States
Primary
Concomitant
Pruritus Generalised Other Serious 1/1/2006 48 Female 143 lb 2/9/2012 Consumer Argentina
Primary
Concomitant
Death Death 7/6/2011 47 Female 143 lb 2/16/2012 Physician Netherlands
Primary
Concomitant
Rheumatoid Nodule Hospitalization 9/9/2010 75 Female 126 lb 5/11/2012 Physician Germany
Primary
Concomitant
Swelling Face Other Serious 4/16/2012 65 Female 134 lb 6/3/2012 Consumer United States
Primary
Concomitant
Lip Swelling Other Serious 4/16/2012 65 Female 134 lb 6/25/2012 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 6/14/2012 60 Female 7/20/2012 Consumer Argentina
Primary
Concomitant
Varicose Vein Other Serious Female 179 lb 8/15/2012 Physician Germany
Primary
Concomitant
Rheumatoid Nodule Hospitalization 9/9/2010 76 Female 126 lb 1/28/2013 Physician De
Primary
Concomitant
Angina Pectoris Hospitalization 3/28/2012 61 Female 163 lb 12/12/2012 Physician Br
Primary
Concomitant
Joint Dislocation Other Serious 56 Female 9/11/2012 Consumer Ar
Primary
Concomitant
Hip Fracture Other Serious 9/2012 34 Female 10/26/2012 Consumer Ar
Primary
Concomitant
Infection 3/6/2012 59 Female 204 lb 10/25/2012 Physician Us
Primary
Concomitant
Pruritus Disability 8/2012 57 Female 12/5/2012 Other Health Professional Gb
Primary
Concomitant
Eye Swelling Other Serious 11/2012 Female 177 lb 12/17/2012 Other Health Professional Ca
Primary
Concomitant
Ovarian Cyst Hospitalization 6/2012 Female 2/19/2013 Consumer Uy
Primary
Secondary
Concomitant
Injection Site Haemorrhage 1/4/2012 34 Female 1/28/2013 Consumer Country Not Specified
Primary
Concomitant
Unevaluable Event Female 1/30/2013 Consumer Country Not Specified
Primary
Concomitant
Injection Site Pruritus 10/2012 Female 1/31/2013 Consumer Country Not Specified
Primary
Concomitant
Pain In Extremity Other Serious 5/2007 58 Female 3/11/2013 Physician Country Not Specified
Primary
Concomitant
Tubulointerstitial Nephritis Hospitalization 7/31/2012 59 Female 163 lb 3/12/2013 Physician Nl
Primary
Secondary
Concomitant
Systemic Lupus Erythematosus Other Serious 12/6/2012 52 Female 177 lb 3/12/2013 Other Health Professional Ca
Primary
Concomitant
Small Intestine Carcinoma Life Threatening 3/5/2013 63 Female 172 lb 4/4/2013 Pharmacist Gb
Primary
Concomitant
Injection Site Rash Other Serious 2011 60 Female 4/26/2013 Other Health Professional Ca
Primary
Concomitant
Suicidal Ideation Other Serious 26 NotSpecified 6/17/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 6/13/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 6/14/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 6/27/2013 Other Health Professional Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 6/17/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 10/16/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 6/20/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 6/20/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 6/21/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 6/24/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 6/24/2013 Consumer Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 6/24/2013 Other Health Professional Gb
Primary
Secondary
Suicidal Ideation Other Serious 26 Female 10/28/2013 Consumer Gb
Primary
Secondary
Diabetic Foot Hospitalization 2/12/2013 56 Female 227 lb 8/22/2013 Other Health Professional Country Not Specified
Primary
Concomitant
Vestibular Neuronitis Hospitalization 6/13/2013 55 Female 152 lb 9/30/2013 Physician De
Primary
Secondary
Concomitant
Pain In Extremity Other Serious Male 176 lb 7/29/2013 Consumer Country Not Specified
Primary
Concomitant
Swollen Tongue Life Threatening 7/31/2013 69 Male 8/23/2013 Other Health Professional Gb
Primary
Concomitant
Sleep Disorder Due To General Medical Condition, Insomnia Type Hospitalization 1/4/2013 59 Male 9/16/2013 Physician Ca
Primary
Concomitant
Drug Ineffective Female 240 lb 10/1/2013 Physician Us
Primary
Concomitant
Sinus Congestion 2/16/2013 56 Female 165 lb 10/1/2013 Physician Us
Primary
Concomitant
Rheumatoid Arthritis 1/1/2012 54 Male 225 lb 10/3/2013 Physician Us
Primary
Concomitant
Musculoskeletal Chest Pain Other Serious 9/26/2013 53 Female 176 lb 11/14/2013 Other Health Professional Ca
Primary
Secondary
Concomitant
Vomiting Hospitalization 6/13/2013 55 Female 152 lb 10/15/2013 Physician De
Primary
Secondary
Concomitant
Pancreatitis Other Serious NotSpecified 10/29/2013 Physician De
Primary
Secondary
Suicidal Ideation Other Serious 26 NotSpecified 11/8/2013 Consumer Gb
Primary
Secondary
Angina Pectoris Hospitalization 3/28/2012 61 Female 163 lb 12/11/2013 Physician Br
Primary
Secondary
Concomitant

Drug Data