Diazepam combined with Topiramate

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Multiple Drug Overdose Accidental Death 7/17/2004 50 Male 2/28/2006 Other Health Professional United States
Primary
Secondary
Laboratory Test Abnormal Other Serious 3/1/2003 38 Female 96 lb 4/7/2006 Physician United States
Primary
Concomitant
Haemodynamic Instability Required Intervention 9 Male 8/31/2006 Physician Belgium
Primary
Concomitant
Myalgia Required Intervention 7/27/2006 47 Male 265 lb 9/20/2006 Pharmacist United States
Primary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/7/2006 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Death Death 39 Female 4/6/2007
Primary
Secondary
Death Death 39 Female 4/18/2007
Primary
Secondary
Rhabdomyolysis Death 36 Female 6/18/2007 Other Health Professional United States
Primary
Concomitant
Poisoning Death 39 Female 6/21/2007 Germany
Primary
Secondary
Concomitant
Intraocular Pressure Increased Other Serious 10/9/2006 Female 141 lb 7/31/2007 Other Health Professional Portugal
Primary
Concomitant
Death Death 12/15/2007 33 Male 12/20/2007 Physician Brazil
Primary
Secondary
Atrial Fibrillation Other Serious 10/25/2007 Female 148 lb 2/29/2008 Physician Germany
Primary
Concomitant
Suicidal Ideation Other Serious 2/1/1999 Female 3/26/2008 Physician United Kingdom
Primary
Concomitant
Suicidal Ideation Other Serious 2/1/1999 Female 4/11/2008 Physician United Kingdom
Primary
Concomitant
Multiple Drug Overdose Death 1/1/2006 50 Male 7/7/2008 Canada
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 1/1/2006 46 Male 7/7/2008 Canada
Primary
Secondary
Concomitant
Joint Sprain 5/31/2008 Male 258 lb 9/2/2008 Physician United States
Primary
Concomitant
Spinal Cord Drainage Other Serious 12/3/2007 30 Female 12/16/2008 Consumer Brazil
Primary
Concomitant
Spinal Cord Drainage Other Serious 11/1/2007 30 Female 12/22/2008 Consumer Brazil
Primary
Concomitant
Completed Suicide Death 39 Female 12/29/2008 Pharmacist United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/8/2009 Other Health Professional United States
Primary
Secondary
Cardio-respiratory Arrest Death 39 Female 1/16/2009 United States
Primary
Secondary
Drug Toxicity Death 39 Female 1/23/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Other Serious 39 Female 1/23/2009 Physician United States
Primary
Secondary
Completed Suicide Death 39 Female 1/28/2009 Other Health Professional United States
Primary
Secondary
Wrong Technique In Drug Usage Process Death 1/14/2004 Female 190 lb 1/29/2009 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 39 Female 1/26/2009 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 1/1/2007 39 Female 2/3/2009 Pharmacist United States
Primary
Secondary
Respiratory Arrest Death 39 Female 2/13/2009 Physician United States
Primary
Secondary
Vision Blurred Hospitalization 12/3/2007 30 Female 2/27/2009 Physician Brazil
Primary
Concomitant
Respiratory Arrest Death 39 Female 3/5/2009 Physician United States
Primary
Secondary
Influenza Like Illness Male 3/12/2009 Consumer United States
Primary
Concomitant
Vaginal Haemorrhage 6/23/1999 28 Female 194 lb 4/15/2009 Other Health Professional United States
Primary
Concomitant
Vertigo Other Serious 38 Male 8/12/2009
Primary
Secondary
Concomitant
Vision Blurred Hospitalization 1/1/2007 30 Female 10/13/2009 Physician Brazil
Primary
Concomitant
Hemiparesis Other Serious 12 Female 10/20/2009 Other Health Professional Poland
Primary
Secondary
Oedema Peripheral Hospitalization 1/1/2008 Female 11/11/2009 Other Health Professional New Zealand
Primary
Secondary
Weight Increased Other Serious 16 Male 11/17/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Weight Increased Hospitalization 16 Male 12/1/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Weight Increased Other Serious 16 Male 12/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Arrest Hospitalization 1/1/2008 51 Female 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 52 Female 1/25/2010 Physician United States
Primary
Secondary
Respiratory Arrest Death 52 Female 1/21/2010 Physician United States
Primary
Secondary
Hypotension Other Serious 50 Female 2/18/2010
Primary
Secondary
Concomitant
Pupil Fixed Other Serious 50 Female 2/23/2010 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 50 Female 2/25/2010 Physician United States
Primary
Concomitant
Penile Exfoliation Required Intervention 9/21/2008 38 Male 225 lb 10/21/2008 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 52 Female 3/2/2010 Physician United States
Primary
Secondary
Listless 11/1/2009 29 Female 3/15/2010 Other Health Professional United States
Primary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 4/12/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Drug Interaction Death 12/15/2007 33 Male 4/13/2010 Physician Brazil
Primary
Secondary
Interacting
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/15/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/16/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 124 lb 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/21/2010 Other Health Professional
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 6/5/2009 23 Male 4/26/2010 Other Health Professional Japan
Primary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/26/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/27/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 4/22/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypertension Hospitalization 1/4/2010 81 Female 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Increased Other Serious Male 4/29/2010 France
Primary
Secondary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 213 lb 4/30/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 12/7/2009 22 Male 5/7/2010 Other Health Professional Japan
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 37 Female 4/30/2010 Physician United States
Primary
Concomitant
Tongue Ulceration Other Serious 11/23/2009 34 Female 5/6/2010 United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 12/7/2009 22 Male 5/14/2010 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Other Serious 12/7/2009 22 Male 5/26/2010 Other Health Professional Japan
Primary
Concomitant
Paranoia Other Serious 11/1/2008 40 Female 6/7/2010 Physician Spain
Primary
Secondary
Concomitant
Somnolence 12/7/2009 22 Male 6/10/2010 Other Health Professional Japan
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/1/2009 38 Female 209 lb 7/2/2010 Consumer United States
Primary
Concomitant
Paranoia Other Serious 11/1/2008 40 Female 7/7/2010 Physician Spain
Primary
Secondary
Concomitant
Narcotic Intoxication Death 7/13/2007 45 Male 214 lb 7/20/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 45 Female 7/23/2010
Primary
Secondary
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 8/10/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/1/2009 38 Female 209 lb 8/23/2010 Consumer United States
Primary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 9/2/2010 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 11/1/2009 38 Female 209 lb 9/9/2010 Consumer United States
Primary
Concomitant
Respiratory Arrest Hospitalization 1/1/2008 51 Female 9/16/2010 Physician United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 16 Male 9/29/2010 Physician United States
Primary
Secondary
Concomitant
Metabolic Acidosis Other Serious 37 Female 10/12/2010 Physician United States
Primary
Concomitant
Suicide Attempt Hospitalization 10/15/2010 Other Health Professional United States
Primary
Concomitant
Status Epilepticus Hospitalization Female 10/8/2010 Physician Norway
Primary
Concomitant
Treatment Noncompliance Other Serious 37 Female 10/21/2010
Primary
Secondary
Suicide Attempt Other Serious 19 Female 165 lb 10/22/2010
Primary
Secondary
Suicide Attempt Required Intervention 37 Female 10/19/2010 Physician United States
Primary
Concomitant
Hypokalaemia Hospitalization 7/14/2010 30 Female 183 lb 11/4/2010 Other Health Professional United States
Primary
Concomitant
Withdrawal Syndrome Death 7/13/2007 45 Male 214 lb 11/15/2010 Other Health Professional United States
Primary
Concomitant
Renal Failure Other Serious 6/1/2010 49 Female 10/25/2010 United States
Primary
Concomitant
Pain In Extremity Other Serious Female 11/16/2010 Consumer Brazil
Primary
Concomitant
Withdrawal Syndrome Death 7/13/2007 45 Male 214 lb 11/18/2010 Other Health Professional United States
Primary
Concomitant
Treatment Noncompliance Other Serious 37 Female 11/12/2010 United States
Primary
Concomitant
Withdrawal Syndrome Death 7/13/2007 45 Male 214 lb 11/29/2010 Other Health Professional United States
Primary
Concomitant
Sepsis Death 1/1/2007 39 Female 11/30/2010
Primary
Secondary
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 12/10/2010 Other Health Professional Japan
Primary
Concomitant
Respiratory Arrest Hospitalization 1/1/2008 51 Female 1/15/2010 Physician United States
Primary
Secondary
Concomitant
Weight Decreased Life Threatening 12/4/2010 28 Female 12/16/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Weight Decreased Life Threatening 12/4/2010 28 Female 12/28/2010 Other Health Professional Japan
Primary
Concomitant
Interacting
Completed Suicide Death 1/1/2009 64 Male 1/7/2011 Physician United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 38 Female 1/10/2011 Physician United States
Primary
Secondary
Feeling Cold Life Threatening 12/4/2010 28 Female 1/12/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Completed Suicide Hospitalization 38 Female 1/12/2011 Physician United States
Primary
Secondary
Completed Suicide Death 64 Male 1/12/2011 Physician United States
Primary
Secondary
Completed Suicide Death 38 Female 1/13/2011 Physician United States
Primary
Secondary
Completed Suicide Death 64 Male 1/13/2011 Physician United States
Primary
Secondary
Weight Decreased Life Threatening 12/4/2010 28 Female 1/14/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Death Death 38 Female 1/18/2011 Physician United States
Primary
Secondary
Blood Amylase Increased 12/4/2010 28 Female 1/20/2011 Other Health Professional Japan
Primary
Concomitant
Interacting
Intentional Drug Misuse Death 38 Female 1/21/2011 Physician United States
Primary
Secondary
Completed Suicide Death 64 Male 1/25/2011 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 1/1/2009 38 Female 1/27/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death 38 Female 2/7/2011 Other Health Professional United States
Primary
Secondary
Poisoning Death 1/1/2009 64 Male 1/27/2011 Physician United States
Primary
Secondary
Drug Eruption Hospitalization 1/9/2010 35 Male 2/11/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Completed Suicide Death 38 Female 2/17/2011 Physician United States
Primary
Secondary
Cardio-respiratory Arrest Death Female 2/7/2011 Physician United States
Primary
Secondary
Drug Interaction Hospitalization 11/16/2010 33 Female 80 lb 2/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 3/3/2011 Other Health Professional Japan
Primary
Concomitant
Completed Suicide Death 38 Female 3/4/2011 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 64 Male 3/9/2011 Physician United States
Primary
Secondary
Hypertension Hospitalization 1/5/2010 81 Female 3/11/2011 Consumer United States
Primary
Secondary
Concomitant
Blood Potassium Decreased Other Serious 37 Female 2/22/2011 Physician United States
Primary
Concomitant
Respiratory Arrest Death 38 Female 3/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 38 Female 3/24/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Death 64 Male 3/24/2011 Physician United States
Primary
Secondary
Sepsis Life Threatening 1/1/2010 59 Male 4/25/2011 Other Health Professional Japan
Primary
Concomitant
Rash Maculo-papular Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Wound Haemorrhage Other Serious 8/1/2007 64 Female 160 lb 4/7/2011 Consumer United States
Primary
Secondary
Concomitant
Completed Suicide Death 63 Female 5/16/2011 Physician Canada
Primary
Secondary
Diplopia Hospitalization 9/1/2010 58 Female 141 lb 6/2/2011 Consumer Canada
Primary
Concomitant
Drug Eruption Hospitalization 1/9/2010 35 Male 6/10/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 7/22/2011 Other Health Professional Japan
Primary
Concomitant
Substance Abuse Death 50 Male 7/25/2011 Physician Canada
Primary
Secondary
Intentional Drug Misuse Death 1/1/2008 52 Female 7/21/2011 Physician United States
Primary
Secondary
Myocardial Infarction Other Serious 12/9/2010 42 Female 171 lb 7/20/2011 Consumer United States
Primary
Secondary
Concomitant
Insomnia Hospitalization 46 Male 8/12/2011 United States
Primary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 8/31/2011 Other Health Professional Japan
Primary
Concomitant
Bradykinesia Hospitalization 46 Male 9/12/2011 Physician Japan
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 46 Male 9/21/2011 Physician Japan
Primary
Secondary
Myoclonus Hospitalization Female 6 lb 9/30/2011 Physician United States
Primary
Secondary
Neuroleptic Malignant Syndrome Other Serious 46 Male 10/17/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Oedema Peripheral Other Serious Female 223 lb 10/19/2011 Physician United Kingdom
Primary
Secondary
Concomitant
Neuroleptic Malignant Syndrome Other Serious 46 Male 10/21/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Overdose Death 9/26/2011 52 Female 123 lb 10/20/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Cellulitis Hospitalization 1/9/2010 35 Male 11/4/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Blood Cholesterol Increased Other Serious Male 11/10/2011 Consumer Canada
Primary
Concomitant

Drug Data