Diazepam combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
White Blood Cell Count Increased Death 30 Male 161 lb 3/10/2006 Other Health Professional Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Other Serious 30 Male 161 lb 4/11/2006 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Life Threatening 30 Male 161 lb 5/5/2006 Spain
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization Female 7/3/2006 Physician Germany
Primary
Concomitant
Tachycardia 4/26/2006 44 Female 7/28/2006 Other Health Professional Italy
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 31 Male 8/7/2006 United States
Primary
Secondary
Concomitant
Ventricular Tachycardia Other Serious 11/6/2006
Primary
Concomitant
Pulmonary Hypertension Other Serious 11/6/2006
Primary
Concomitant
Lung Disorder Other Serious 11/6/2006
Primary
Concomitant
Ventricular Dysfunction Hospitalization 31 Female 11/16/2006 Consumer Canada
Primary
Secondary
Ventricular Dysfunction Other Serious 31 Female 11/27/2006 Physician Canada
Primary
Secondary
Concomitant
Vasculitis Other Serious 11/1/2006 23 Male 12/8/2006 Physician Turkey
Primary
Secondary
Concomitant
Intra-uterine Death Death 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 31 Female 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Tachycardia Life Threatening 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Ultrasound Scan Abnormal Other Serious 46 Female 12/21/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachycardia Other Serious 46 Female 12/21/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/22/2006
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/29/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Required Intervention 1/1/2006 46 Female 12/22/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 10/30/2006 46 Female 12/22/2006 United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 12/28/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Life Threatening 46 Female 12/30/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Tachypnoea Other Serious 46 Female 1/15/2007 United Kingdom
Primary
Secondary
Concomitant
Pyoderma Gangrenosum Hospitalization 1/8/2003 24 Female 1/25/2007 Physician Finland
Primary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/13/2007 Physician Norway
Primary
Secondary
Concomitant
Post Procedural Bile Leak Life Threatening 7/5/2004 51 Male 4/30/2007 Physician Norway
Primary
Secondary
Concomitant
Rhabdomyolysis Death 36 Female 6/18/2007 Other Health Professional United States
Primary
Concomitant
Ventricular Dysfunction Death 36 Female 6/14/2007 Physician United States
Primary
Concomitant
Ventricular Tachycardia Death 6/8/2007 44 Male 187 lb 6/15/2007 Pharmacist Canada
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/9/2007 Japan
Primary
Secondary
Concomitant
Patent Ductus Arteriosus Life Threatening 5/22/2007 0 Female 2 lb 7/24/2007 Physician Germany
Primary
Concomitant
Sinus Tachycardia Life Threatening 8/18/2006 63 Male 7/26/2007 Japan
Primary
Secondary
Concomitant
Electroencephalogram Abnormal Other Serious 28 Male 8/21/2007 Other Health Professional India
Primary
Concomitant
Psychomotor Hyperactivity Required Intervention 60 Female 9/12/2007 Physician Brazil
Primary
Secondary
Concomitant
Pulmonary Congestion Other Serious 4/8/2004 59 Male 9/14/2007 Physician Japan
Primary
Concomitant
Drug Effect Decreased Other Serious 58 Female 11/30/2007
Primary
Concomitant
Heart Rate Abnormal Required Intervention 58 Female 11/27/2007 Consumer Australia
Primary
Concomitant
Drug Interaction Other Serious 15 Female 12/18/2007 Other Health Professional Greece
Primary
Concomitant
Interacting
Stevens-johnson Syndrome Life Threatening 9/13/2004 75 Female 1/28/2008 Physician Germany
Primary
Secondary
Concomitant
Post Procedural Discharge Other Serious 9/26/2007 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 9/13/2004 Female 3/3/2008 Physician Germany
Primary
Concomitant
Toxic Epidermal Necrolysis Life Threatening 9/13/2004 75 Female 2/27/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Life Threatening 9/13/2004 Female 3/17/2008 Physician Germany
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 3/26/2008 Lawyer United States
Primary
Concomitant
Hypertension 61 Female 3/31/2008 Japan
Primary
Secondary
Concomitant
Toxic Encephalopathy Hospitalization 49 Female 4/17/2008 Physician Canada
Primary
Secondary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/1/2008 Lawyer United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 5/14/2008 Lawyer United States
Primary
Concomitant
Quadriplegia 4/27/2008 83 Male 6/2/2008 Japan
Primary
Concomitant
Overdose Other Serious 5/1/2008 Female 287 lb 6/18/2008 Physician Bulgaria
Primary
Concomitant
Quadriplegia 4/27/2008 83 Male 6/24/2008 Japan
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 Female 287 lb 7/2/2008 Physician Bulgaria
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 8/7/2008 Lawyer United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 8/19/2008 Lawyer United States
Primary
Concomitant
Stomach Discomfort Other Serious 12/1/2006 Male 9/10/2008 Lawyer United States
Primary
Concomitant
Respiratory Failure Other Serious 1/1/2008 Female 287 lb 9/15/2008 Physician Bulgaria
Primary
Concomitant
Troponin Increased Hospitalization 49 Female 9/19/2008 Canada
Primary
Secondary
Toxic Encephalopathy Required Intervention 49 Female 9/22/2008 Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 9/25/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Grand Mal Convulsion Hospitalization 8/27/2008 61 Male 229 lb 11/21/2008 Pharmacist Canada
Primary
Secondary
Concomitant
Hypotension Life Threatening 9/27/2008 50 Female 12/12/2008 Denmark
Primary
Secondary
Concomitant
Completed Suicide Other Serious 41 Female 1/23/2009 Physician United States
Primary
Secondary
Splenomegaly Other Serious 12/1/2006 Male 1/29/2009 Lawyer United States
Primary
Concomitant
Hypotension Hospitalization 9/5/2008 Male 1/29/2009 Other Health Professional France
Primary
Concomitant
Interacting
Myocardial Ischaemia Life Threatening 9/4/2007 Female 119 lb 2/2/2009 Physician Japan
Primary
Concomitant
Myocardial Ischaemia Life Threatening 9/4/2007 Female 119 lb 2/12/2009 Physician Japan
Primary
Concomitant
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 51 Female 2/27/2009 Physician Israel
Primary
Concomitant
Pneumonia Other Serious 4/17/2008 27 Female 2/17/2009 Other Health Professional United States
Primary
Concomitant
Sinus Bradycardia Hospitalization 41 Female 3/5/2009 Physician United States
Primary
Secondary
Reversible Posterior Leukoencephalopathy Syndrome Life Threatening 51 Female 141 lb 3/12/2009 Physician Israel
Primary
Concomitant
Speech Disorder Hospitalization 12/1/2006 29 Female 3/19/2009
Primary
Secondary
Concomitant
Respiratory Failure Other Serious Male 3/20/2009 Other Health Professional Sweden
Primary
Secondary
Concomitant
Staphylococcal Infection Hospitalization 3/23/2005 Male 7/7/2009 Consumer Germany
Primary
Secondary
Concomitant
Sinus Arrhythmia Other Serious 46 Male 176 lb 7/30/2009
Primary
Secondary
Concomitant
Implant Site Infection Hospitalization 4/1/2009 39 Male 8/10/2009 Sweden
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6 Female 9/1/2009 Physician Spain
Primary
Secondary
Musculoskeletal Stiffness Other Serious 71 Male 132 lb 9/4/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Toxicity Death 6/25/2009 49 Male 9/10/2009 Consumer United States
Primary
Secondary
Rhabdomyolysis Other Serious 37 Male 135 lb 9/10/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Diabetic Coma Other Serious 5/6/2007 52 Female 122 lb 9/23/2009 United States
Primary
Concomitant
Oxygen Saturation Decreased Other Serious 71 Male 132 lb 9/24/2009 Physician Japan
Primary
Secondary
Concomitant
Drug Toxicity Death 6/25/2009 49 Male 9/24/2009 Consumer United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 38 Female 231 lb 10/22/2009
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 12/27/2009 38 Female 165 lb 1/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Heart Rate Increased Other Serious 1/6/2010
Primary
Secondary
Concomitant
Liver Disorder Male 159 lb 1/27/2010 Japan
Primary
Concomitant
Liver Injury Hospitalization 6/13/2009 80 Female 130 lb 1/25/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 2/18/2010 Lawyer United States
Primary
Concomitant
Post Procedural Complication Hospitalization 6/13/2009 80 Female 130 lb 2/9/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Restlessness Hospitalization 9/5/2008 54 Male 2/24/2010 Other Health Professional Sweden
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 3/22/2010 Physician Germany
Primary
Secondary
Concomitant
Renal Failure Acute Life Threatening 3/9/2010 76 Male 4/27/2010 Physician Japan
Primary
Secondary
Concomitant
Renal Failure Acute Other Serious 24 Female 4/29/2010
Primary
Secondary
Unresponsive To Stimuli Other Serious 11/29/2007 50 Male 5/3/2010 Other Health Professional United States
Primary
Concomitant
Cholangitis Other Serious 5/9/2003 5/13/2010 Physician Finland
Primary
Secondary
Concomitant
Pneumonia Aspiration Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 35 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pneumonia Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Cholangitis Hospitalization 5/9/2003 5/24/2010 Physician Finland
Primary
Secondary
Concomitant
Tachypnoea Other Serious 18 Female 110 lb 6/8/2010
Primary
Secondary
Renal Failure Acute Life Threatening 3/9/2010 76 Male 6/9/2010 Physician Japan
Primary
Secondary
Concomitant
Stomatitis Other Serious 9/17/2007 70 Female 6/30/2010 Physician Germany
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 46 Female 7/19/2010 Physician United States
Primary
Concomitant
Interacting
Septic Shock Life Threatening 1/13/2009 60 Male 103 lb 7/21/2010 Physician Taiwan, Province Of China
Primary
Concomitant
Respiratory Depression Other Serious 46 Male 7/29/2010
Primary
Secondary
Neonatal Respiratory Failure Hospitalization 6/26/2010 Male 5 lb 9/20/2010 Physician Japan
Primary
Concomitant
Threatened Labour Hospitalization 6/25/2010 29 Female 121 lb 9/21/2010 Physician Japan
Primary
Concomitant
Hypoxia Other Serious 76 Female 110 lb 9/30/2010 Other Health Professional Romania
Primary
Secondary
Hypoxia Other Serious 52 Male 265 lb 9/30/2010 Other Health Professional Romania
Primary
Secondary
Threatened Labour Hospitalization 6/25/2010 29 Female 121 lb 10/5/2010 Physician Japan
Primary
Concomitant
Suicide Attempt Other Serious 19 Female 165 lb 10/22/2010
Primary
Secondary
Drug Toxicity Death 6/25/2009 49 Male 10/29/2010 Consumer United States
Primary
Secondary
Wound Haemorrhage Other Serious 12/1/2007 57 Female 12/2/2010 Other Health Professional United States
Primary
Concomitant
Unresponsive To Stimuli Other Serious 11/1/2007 50 Male 262 lb 12/20/2010 Other Health Professional United States
Primary
Concomitant
Urticaria Other Serious 12/8/2010 35 Female 128 lb 1/5/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Other Serious 9/19/2007 70 Female 1/10/2011 Physician Germany
Primary
Secondary
Concomitant
Overdose Hospitalization 10/28/2010 1 Male 12/28/2010 France
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/12/2011 Physician Germany
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 70 Female 1/26/2011 Physician Germany
Primary
Secondary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 1/1/2007 28 Female 121 lb 2/23/2011 Physician Japan
Primary
Concomitant
Drug Interaction Other Serious 49 Female 3/23/2011 Other Health Professional Australia
Primary
Concomitant
Dystonia Hospitalization 16 Female 4/8/2011 Physician Norway
Primary
Secondary
Concomitant
Fear Of Death Other Serious 11/11/2004 65 Male 185 lb 4/13/2011 Consumer United States
Primary
Concomitant
Chorea Hospitalization 3/10/2011 15 Female 4/19/2011 Physician Norway
Primary
Secondary
Concomitant
Injury Other Serious 3/19/2000 35 Female 163 lb 6/8/2011 Lawyer United States
Primary
Concomitant
Arteriospasm Coronary Life Threatening 63 Male 152 lb 6/27/2011 Physician Japan
Primary
Secondary
Concomitant
Death Death 12/9/2005 79 Female 134 lb 6/22/2011 Consumer United States
Primary
Concomitant
Fear Of Death Other Serious 11/11/2004 65 Male 185 lb 6/30/2011 Physician United States
Primary
Concomitant
Renal Injury Other Serious 65 Male 185 lb 7/8/2011 Other Health Professional United States
Primary
Concomitant
Unevaluable Event Hospitalization 3/19/2000 35 Female 163 lb 7/19/2011 Lawyer United States
Primary
Concomitant
Renal Impairment Other Serious 7/26/2011 Other Health Professional Italy
Primary
Concomitant
Hepatic Function Abnormal Other Serious 69 Male 7/22/2011 Physician United States
Primary
Concomitant
Renal Impairment Other Serious 31 Male 8/15/2011 Other Health Professional Italy
Primary
Concomitant
Anxiety Other Serious 6/22/2005 56 Male 251 lb 8/24/2011 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 9/19/2007 9/21/2011 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Fibrillation Other Serious 71 Female 88 lb 9/29/2011 Other Health Professional Japan
Primary
Secondary
Nikolsky's Sign Other Serious 8/15/2009 45 Male 176 lb 10/5/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Cardiac Failure Death 6/24/2009 84 Female 86 lb 10/14/2011 Physician Japan
Primary
Concomitant
Scab Death 8/15/2009 45 Male 176 lb 11/1/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Bradycardia Other Serious 60 Male 11/9/2011 Physician United States
Primary
Secondary
Bradycardia Other Serious 59 Male 11/9/2011 Physician United States
Primary
Secondary
Hypoxic-ischaemic Encephalopathy Death 10/22/2011 48 Male 190 lb 11/10/2011 Pharmacist United States
Primary
Concomitant
Bradycardia Other Serious 60 Male 11/23/2011 Physician United States
Primary
Secondary
Bradycardia Other Serious 59 Male 11/23/2011 Physician United States
Primary
Secondary
Bronchospasm Life Threatening 47 Female 11/17/2011 Other Health Professional Japan
Primary
Concomitant
Anaphylactic Reaction Life Threatening 71 Female 88 lb 2/29/2012 Other Health Professional Japan
Primary
Secondary
Meningeal Disorder Hospitalization 11/25/2011 81 Male 2/29/2012 Physician Germany
Primary
Secondary
Concomitant
Coma Hospitalization 11/25/2011 81 Male 3/6/2012 Physician Germany
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 8/10/2008 53 Male 3/22/2012 Other Health Professional United States
Primary
Concomitant

Drug Data