Diazepam combined with Phenytoin

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Upper Gastrointestinal Haemorrhage Hospitalization 1/1/2002 61 Female 90 lb 3/29/2006 Physician United States
Primary
Concomitant
Upper Gastrointestinal Haemorrhage Hospitalization 1/1/2002 61 Female 90 lb 4/3/2006 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 56 Female 6/16/2006 Other Health Professional United States
Primary
Secondary
Hypotension Other Serious 5/8/2006 80 Male 166 lb 5/8/2006 Pharmacist United States
Primary
Concomitant
Pyrexia Hospitalization 8/15/2006 79 Male 165 lb 8/15/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Rash Other Serious 8/1/2006 47 Male 166 lb 8/14/2006 United States
Primary
Secondary
Concomitant
Purple Glove Syndrome Other Serious 8/1/2006 47 Male 166 lb 8/17/2006 Pharmacist United States
Primary
Secondary
Concomitant
Blood Ph Decreased Hospitalization 61 Male 8/17/2006 United States
Primary
Concomitant
Haemodynamic Instability Required Intervention 9 Male 8/31/2006 Physician Belgium
Primary
Concomitant
Renal Failure Acute Required Intervention 9/14/2006 20 Male 9/25/2006 Physician Japan
Primary
Secondary
Visceral Oedema Death 1/1/1999 56 Female 10/9/2006 United States
Primary
Secondary
Renal Failure Acute Required Intervention 9/14/2006 20 Male 10/5/2006 Physician Japan
Primary
Secondary
Renal Hypertension Life Threatening 9/15/2006 20 Male 10/16/2006 Physician Japan
Primary
Secondary
Sudden Death Death 35 Female 10/31/2006 Physician India
Primary
Concomitant
Skin Discolouration Hospitalization 14 Male 44 lb 11/10/2006 Physician Japan
Primary
Secondary
Concomitant
Psychotic Disorder Disability 3/1/2006 43 220 lb 11/9/2006 Other Health Professional United Kingdom
Primary
Concomitant
Vomiting Life Threatening 9/15/2006 20 Male 11/21/2006 Physician Japan
Primary
Secondary
Intra-uterine Death Death 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Renal Impairment Required Intervention 31 Female 11/30/2006 Physician Canada
Primary
Secondary
Concomitant
Restlessness Death 5/21/2003 69 Male 2/2/2007 Other Health Professional Japan
Primary
Concomitant
Panic Attack Other Serious 44 Male 4/23/2007 United States
Primary
Concomitant
Small Intestinal Obstruction Hospitalization 21 Male 5/25/2007 United States
Primary
Secondary
Concomitant
Transient Hypogammaglobulinaemia Of Infancy Other Serious 3 Male 8/28/2007
Primary
Secondary
Somnolence Hospitalization 22 Female 9/8/2007 Japan
Primary
Concomitant
Urine Ketone Body Present Death 36 Female 8/23/2007 United States
Primary
Secondary
Concomitant
Splenomegaly Death 3/12/2007 32 Male 165 lb 8/31/2007 United States
Primary
Secondary
Concomitant
Somnolence Hospitalization 22 Female 9/20/2007 Japan
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 9/24/2007 Brazil
Primary
Secondary
Concomitant
Hypogammaglobulinaemia Required Intervention 3 Male 9/26/2007 Japan
Primary
Secondary
Concomitant
Vomiting Required Intervention 9/12/2007 33 Female 10/8/2007 Pharmacist Canada
Primary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 10/9/2007 Brazil
Primary
Secondary
Concomitant
Stevens-johnson Syndrome Hospitalization 10/14/2005 32 Female 11/1/2007 Brazil
Primary
Secondary
Concomitant
Pulmonary Oedema Death 3/12/2007 32 Male 165 lb 10/11/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 15 Female 12/18/2007 Other Health Professional Greece
Primary
Concomitant
Interacting
Panic Attack Other Serious 44 Male 200 lb 11/13/2007 United States
Primary
Secondary
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 22 Male 1/24/2008 Physician United Kingdom
Primary
Concomitant
Status Epilepticus Other Serious 2/4/2008 36 Female 2/27/2008 Other Health Professional United Kingdom
Primary
Secondary
Vomiting Hospitalization 2/23/2005 76 Male 104 lb 2/27/2008 Physician Japan
Primary
Concomitant
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 2/26/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 11/1/2002 Male 3/3/2008 Physician Germany
Primary
Secondary
Toxic Epidermal Necrolysis Hospitalization 12/18/2002 76 Male 4/10/2008 Physician Germany
Primary
Secondary
Injection Site Pain 3/1/2008 Female 200 lb 6/12/2008 United States
Primary
Concomitant
Stevens-johnson Syndrome Life Threatening 8/1/2007 42 Male 130 lb 6/25/2008 Pharmacist United States
Primary
Concomitant
Visual Acuity Reduced Other Serious 11/21/2005 Male 7/25/2008 Physician United States
Primary
Concomitant
Somnambulism Other Serious 54 Female 8/11/2008 Other Health Professional Canada
Primary
Secondary
Concomitant
Visual Impairment Other Serious 11/19/2005 Male 8/20/2008 Physician United States
Primary
Concomitant
Vomiting Other Serious 1 Female 10/3/2008 Physician Netherlands
Primary
Secondary
Rhabdomyolysis Other Serious 67 Male 11/20/2008 Physician Austria
Primary
Concomitant
Interacting
Status Epilepticus Hospitalization 35 Female 12/11/2008 Other Health Professional Germany
Primary
Concomitant
Interacting
Vomiting Hospitalization 23 Female 12/11/2008 Pharmacist India
Primary
Secondary
Concomitant
Vomiting Hospitalization 23 Female 12/17/2008 Other Health Professional India
Primary
Secondary
Concomitant
Sepsis Hospitalization 3/8/1988 Male 165 lb 12/18/2008 Physician Canada
Primary
Secondary
Concomitant
Porphyria Acute Hospitalization 23 Female 12/19/2008 Other Health Professional Germany
Primary
Secondary
Porphyria Acute Hospitalization 23 Female 12/22/2008 Pharmacist India
Primary
Secondary
Concomitant
Porphyria Acute Hospitalization 23 Female 12/22/2008 Pharmacist India
Primary
Secondary
Concomitant
Vitamin B6 Decreased Other Serious 1/1/2007 81 Female 99 lb 1/5/2009
Primary
Secondary
Concomitant
Status Epilepticus Other Serious 1/1/2007 81 Female 99 lb 1/5/2009
Primary
Secondary
Concomitant
Vomiting Hospitalization 23 Female 12/22/2008 Pharmacist India
Primary
Secondary
Concomitant
Porphyria Acute Hospitalization 1/1/2008 23 Female 1/28/2009 Other Health Professional India
Primary
Secondary
Rash Other Serious 1/12/2009 2/23/2009 Pharmacist Ireland
Primary
Secondary
Concomitant
Vision Blurred Other Serious 3 Male 4/28/2009 Other Health Professional Germany
Primary
Secondary
Hepatomegaly Other Serious 13 Female 110 lb 5/11/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/1997 47 Male 204 lb 5/14/2009 United States
Primary
Secondary
Concomitant
Wheezing Other Serious 8/6/2001 25 Male 256 lb 5/21/2009 United States
Primary
Concomitant
Embolic Cerebral Infarction Other Serious 6 Male 6/12/2009
Primary
Secondary
Concomitant
Hepatomegaly Other Serious 13 Female 6/18/2009 Physician United States
Primary
Secondary
Concomitant
Aphasia 6/23/2009 14 Male 7/2/2009 Pharmacist United States
Primary
Concomitant
Wheezing Hospitalization 11/24/2008 56 Male 169 lb 6/22/2009 Physician United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 140 lb 7/16/2009 United States
Primary
Concomitant
Porphyria Acute Hospitalization 23 Female 7/27/2009 Other Health Professional Malaysia
Primary
Secondary
Concomitant
Sinus Arrhythmia Other Serious 46 Male 176 lb 7/30/2009
Primary
Secondary
Concomitant
Atrial Fibrillation Other Serious 6/18/2009 Female 8/3/2009 Physician United Kingdom
Primary
Concomitant
Temporomandibular Joint Syndrome Other Serious 56 Female 8/14/2009 Canada
Primary
Secondary
Concomitant
Petit Mal Epilepsy Hospitalization 52 Female 98 lb 8/25/2009 Other Health Professional United Kingdom
Primary
Concomitant
Malignant Neoplasm Progression Other Serious 6 Female 9/1/2009 Physician Spain
Primary
Secondary
Pulmonary Fibrosis Other Serious 66 Male 9/8/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 9/10/2009 Physician Japan
Primary
Concomitant
Vomiting Hospitalization 23 Female 9/4/2009 Physician India
Primary
Concomitant
Interstitial Lung Disease Life Threatening 66 Male 9/28/2009 Other Health Professional Japan
Primary
Secondary
Concomitant
Withdrawal Syndrome Hospitalization Female 10/1/2009 Other Health Professional Denmark
Primary
Secondary
Concomitant
Purple Glove Syndrome Hospitalization 55 Male 10/21/2009 Physician United Kingdom
Primary
Concomitant
Sleep Disorder Other Serious 9/1/2009 70 Female 110 lb 11/4/2009 Consumer Brazil
Primary
Secondary
Concomitant
Visual Impairment Other Serious 11/19/2005 Male 11/30/2009 Physician United States
Primary
Concomitant
Wheezing Hospitalization 11/24/2008 56 Male 169 lb 11/16/2009 Physician United States
Primary
Concomitant
Wrong Drug Administered Other Serious 11/11/2009 27 Male 3/18/2010 Other Health Professional France
Primary
Concomitant
Periodontitis Other Serious 42 Male 4/29/2010 Other Health Professional Japan
Primary
Concomitant
Tooth Resorption Other Serious 6/4/2007 42 Male 5/20/2010 Japan
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 5/24/2010 Lawyer United States
Primary
Concomitant
Tooth Resorption Other Serious 6/4/2007 42 Male 6/1/2010 Other Health Professional Japan
Primary
Concomitant
Status Epilepticus Life Threatening 4/7/2010 25 Female 110 lb 5/26/2010 Physician Japan
Primary
Concomitant
Rash Erythematous Hospitalization 1 Female 6/16/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Granulocytopenia Other Serious 4/12/2010 25 Male 143 lb 6/24/2010 Pharmacist United States
Primary
Concomitant
Interstitial Lung Disease Other Serious 66 Male 6/24/2010 Physician Japan
Primary
Concomitant
Rash Erythematous Hospitalization 1 Female 6/25/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 6/12/2010 3 Male 33 lb 7/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Unresponsive To Stimuli Other Serious 1/27/2008 41 Female 7/22/2010 Lawyer United States
Primary
Concomitant
Drug Interaction Other Serious 22 Female 8/2/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Interacting
Vomiting Hospitalization 2/23/2005 76 Male 104 lb 8/30/2010 Physician Japan
Primary
Secondary
Concomitant
Vomiting Other Serious 9/11/2010 1 Male 10/18/2010 Consumer Brazil
Primary
Secondary
Pancytopenia Life Threatening 3/6/1985 61 Female 10/27/2010 Other Health Professional Japan
Primary
Secondary
Concomitant
Haematemesis Life Threatening 6/23/2010 8 Male 37 lb 11/15/2010 Physician Thailand
Primary
Secondary
Concomitant
Gastrointestinal Haemorrhage Life Threatening 6/23/2010 8 Male 35 lb 12/3/2010 Physician Thailand
Primary
Secondary
Concomitant
Staring Other Serious Female 11/17/2010 Consumer Germany
Primary
Secondary
Concomitant
Death Death 12/15/2010 Physician Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/12/2010 38 Male 154 lb 12/17/2010 Other Health Professional Japan
Primary
Secondary
Hypoglycaemia Other Serious 9/21/2010 94 Female 11/30/2010 Japan
Primary
Concomitant
Death Death 12/23/2010 Other Health Professional Spain
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 8/12/2010 38 Male 154 lb 12/29/2010 Other Health Professional Japan
Primary
Secondary
Renal Impairment Death 1/3/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Conversion Disorder Hospitalization 48 Female 1/4/2011 Other Health Professional United States
Primary
Secondary
Urticaria Other Serious 12/8/2010 35 Female 128 lb 1/5/2011 Pharmacist Portugal
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2009 41 Male 1/10/2011 Physician United States
Primary
Secondary
Death Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Drug Interaction Death 1/17/2011 Physician Japan
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 41 Male 1/19/2011 Physician United States
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 1/20/2011 Physician Thailand
Primary
Secondary
Concomitant
Drug Interaction Death 1/25/2011 Consumer Japan
Primary
Secondary
Concomitant
Accidental Exposure Death 41 Male 2/7/2011 Other Health Professional United States
Primary
Secondary
Poisoning Death 1/1/2009 41 Male 1/27/2011 Physician United States
Primary
Secondary
Respiratory Arrest Death 41 Male 1/20/2011 United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 41 Male 1/26/2011 Physician United States
Primary
Secondary
Cardiac Failure Hospitalization 5/17/2010 2/18/2011 Physician Japan
Primary
Concomitant
Drug Rash With Eosinophilia And Systemic Symptoms Hospitalization 1/1/2007 28 Female 121 lb 2/23/2011 Physician Japan
Primary
Concomitant
Drug Interaction Hospitalization 11/16/2010 33 Female 80 lb 2/15/2011 Other Health Professional Japan
Primary
Secondary
Concomitant
Multiple Drug Overdose Accidental Death 41 Male 3/9/2011 Physician United States
Primary
Secondary
Gastrointestinal Haemorrhage Hospitalization 6/23/2010 8 Male 35 lb 3/24/2011 Physician Thailand
Primary
Secondary
Concomitant
Cardiac Arrest Death 41 Male 3/24/2011 Physician United States
Primary
Secondary
Cerebral Infarction Hospitalization 6/23/2010 8 Male 35 lb 4/12/2011 Physician Thailand
Primary
Secondary
Concomitant
Renal Cancer Hospitalization 11/1/2007 62 Female 145 lb 4/26/2011 Consumer United States
Primary
Concomitant
Erythema Other Serious 4/4/2011 2 Male 24 lb 4/29/2011 Other Health Professional United Kingdom
Primary
Concomitant
Back Pain Hospitalization 3/1/2000 39 Male 5/9/2011 Physician United States
Primary
Concomitant
Lower Respiratory Tract Infection Hospitalization Male 5/3/2011 Pharmacist Ireland
Primary
Concomitant
Hypoxic-ischaemic Encephalopathy Hospitalization 5 5/16/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Aphasia Hospitalization Male 5/6/2011 United Kingdom
Primary
Secondary
Concomitant
Pallor Other Serious 4/4/2011 2 Male 5/9/2011 Other Health Professional United Kingdom
Primary
Concomitant
Motor Dysfunction Hospitalization 5 Male 5/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoxic-ischaemic Encephalopathy Hospitalization 5 Male 5/24/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Movement Disorder Other Serious Male 5/25/2011 United Kingdom
Primary
Secondary
Concomitant
Ischaemia Other Serious Male 5/25/2011 United Kingdom
Primary
Secondary
Concomitant
Brain Oedema Other Serious Male 5/25/2011 United Kingdom
Primary
Secondary
Concomitant
Brain Oedema Hospitalization 5 Male 5/27/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Encephalopathy Disability 5 Male 5/18/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Status Epilepticus Hospitalization 5 Male 6/2/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Hypoglycaemia Other Serious 9/21/2010 94 Female 6/3/2011 Physician Japan
Primary
Concomitant
Atonic Seizures Hospitalization 5 Male 6/3/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Brain Oedema Other Serious 5 Male 5/31/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pruritus Other Serious 1/1/2003 31 Female 6/10/2011 Consumer United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Hospitalization 4/27/2010 79 Female 6/13/2011 Other Health Professional Japan
Primary
Concomitant
Dizziness Hospitalization 11/1/2007 62 Female 145 lb 6/13/2011 Physician United States
Primary
Concomitant

Drug Data