Diazepam combined with Methadone

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Grand Mal Convulsion Other Serious 3/1/2005 Female 1/4/2006 Pharmacist United States
Primary
Concomitant
Vomiting Death 7/10/2005 37 Male 154 lb 2/17/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Respiratory Rate Increased Other Serious 1/1/2003 Female 140 lb 2/27/2006 Pharmacist United States
Primary
Concomitant
Intentional Drug Misuse Death 46 3/9/2006 United States
Primary
Secondary
Intentional Drug Misuse Death 35 3/9/2006 United States
Primary
Secondary
Pregnancy Other Serious 8/16/2007 27 Female 11/7/2007 Denmark
Primary
Concomitant
Pain Disability 9/1/2007 30 Female 11/19/2007 United Kingdom
Primary
Concomitant
Pain Disability 9/1/2007 30 Female 11/27/2007 Other Health Professional United Kingdom
Primary
Concomitant
Respiratory Arrest Other Serious 47 Male 7/11/2008 Physician United States
Primary
Secondary
Respiratory Arrest Other Serious 38 Male 7/11/2008 Physician United States
Primary
Secondary
Completed Suicide Death 59 7/11/2008 Physician United States
Primary
Secondary
Completed Suicide Death 1/1/2007 61 Female 12/23/2008 Physician United States
Primary
Secondary
Somnolence Hospitalization 1/1/2008 2/4/2009 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Arrest Death 1/1/2006 38 Male 3/20/2009 Physician United States
Primary
Secondary
Therapeutic Agent Toxicity Other Serious 10/10/2007 Male 190 lb 3/30/2009 Consumer
Primary
Secondary
Concomitant
Weight Increased Other Serious 8/1/2005 42 Female 257 lb 4/3/2009 United States
Primary
Concomitant
Confusional State Hospitalization 1/1/2009 61 Male 168 lb 5/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/8/2001 49 Female 270 lb 5/19/2009 United States
Primary
Concomitant
Blood Glucose Abnormal Female 5/27/2009 United States
Primary
Concomitant
Blood Glucose Increased Male 5/27/2009 United States
Primary
Concomitant
Bone Pain Female 5/28/2009 Consumer United States
Primary
Concomitant
Drug Toxicity Other Serious 28 Male 6/12/2009 Physician United States
Primary
Secondary
Wrong Technique In Drug Usage Process 1/1/2009 Female 185 lb 6/17/2009 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 45 Male 6/17/2009 Consumer United States
Primary
Secondary
Concomitant
Formication Other Serious 8/12/2008 35 Male 6/18/2009 Other Health Professional Ireland
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 6/19/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Syncope Death 27 Female 6/20/2009 Physician United States
Primary
Secondary
Overdose Death 27 Female 6/23/2009 Other Health Professional United States
Primary
Secondary
Multiple Drug Overdose Accidental Death 1/1/2009 27 Female 6/25/2009 Other Health Professional United States
Primary
Secondary
Pulmonary Congestion Other Serious 28 Male 6/26/2009 Physician United States
Primary
Secondary
Weight Decreased Other Serious 45 Male 6/30/2009 Consumer United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/2/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 5/6/2005 Female 164 lb 7/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Dysarthria Other Serious 34 Male 7/1/2009 Physician United Kingdom
Primary
Concomitant
Weight Decreased Other Serious 45 Male 7/10/2009 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 21 Male 8/3/2009 Other Health Professional United States
Primary
Interacting
Breathing-related Sleep Disorder Disability 30 Female 8/7/2009
Primary
Secondary
Pneumonitis Hospitalization 7/10/2009 56 Female 8/18/2009 United States
Primary
Concomitant
Asthma Hospitalization 5/7/2009 33 Female 8/20/2009 Consumer United Kingdom
Primary
Concomitant
Rhabdomyolysis Other Serious 21 Male 8/25/2009 Other Health Professional Ireland
Primary
Secondary
Syncope Other Serious 27 Female 8/25/2009
Primary
Secondary
Completed Suicide Death 8/31/2009 Physician United States
Primary
Secondary
Pneumonia Other Serious 42 9/4/2009 Other Health Professional Germany
Primary
Secondary
Incorrect Dose Administered 6/25/2007 Female 160 lb 9/11/2009 Consumer United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/30/2005 43 Female 329 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Other Serious 4/1/2001 42 Male 211 lb 9/23/2009 United States
Primary
Concomitant
Drug Toxicity Death 58 Male 9/24/2009 Other Health Professional Germany
Primary
Concomitant
Asthma Hospitalization 5/7/2009 33 Female 10/2/2009 Consumer United Kingdom
Primary
Concomitant
Sepsis Other Serious 1/1/2007 49 Male 10/29/2009 Lawyer United States
Primary
Secondary
Concomitant
Cardiac Flutter Hospitalization 10/1/2009 44 Female 175 lb 11/13/2009 Consumer United States
Primary
Secondary
Concomitant
Condition Aggravated Hospitalization 44 Female 175 lb 12/4/2009 United States
Primary
Secondary
Concomitant
Narcotic Intoxication Other Serious 49 Male 290 lb 12/15/2009 Physician United States
Primary
Secondary
Concomitant
Hepatic Enzyme Abnormal Other Serious 12/27/2009 38 Female 165 lb 1/5/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Premature Baby Other Serious 6/1/2003 Male 5 lb 1/11/2010 Ireland
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 26 Male 1/15/2010 Physician United States
Primary
Secondary
Drug Toxicity Death 21 Male 1/21/2010 Other Health Professional United States
Primary
Secondary
Completed Suicide Death 26 Male 1/20/2010 United States
Primary
Secondary
Sepsis Other Serious 1/1/2007 49 Male 2/1/2010 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Other Serious 5/24/2008 41 Female 220 lb 2/8/2010 Physician Finland
Primary
Concomitant
Respiratory Arrest Death 1/1/2008 26 Male 2/2/2010 Physician United States
Primary
Secondary
Breathing-related Sleep Disorder Disability 30 Female 2/18/2010
Primary
Secondary
Completed Suicide Death 26 Male 2/22/2010 United States
Primary
Secondary
Respiratory Depression Death 0 Male 11 lb 2/23/2010 United Kingdom
Primary
Secondary
Multiple Drug Overdose Death 41 Female 178 lb 2/27/2010 Physician United States
Primary
Secondary
Concomitant
Wrong Technique In Drug Usage Process Death Female 210 lb 3/1/2010 Physician United States
Primary
Secondary
Drug Toxicity Death Male 164 lb 3/1/2010 Physician United States
Primary
Secondary
Intentional Overdose Death 12/19/2009 51 Female 3/2/2010 Physician Germany
Primary
Secondary
Concomitant
Urinary Incontinence Other Serious 6/1/2009 Female 3/2/2010 Physician United Kingdom
Primary
Concomitant
Completed Suicide Death 26 Male 3/4/2010 Other Health Professional United States
Primary
Secondary
Respiratory Arrest Death 3/4/2010 Physician United States
Primary
Secondary
Death Death 37 Male 3/19/2010 Other Health Professional Australia
Primary
Concomitant
Intentional Drug Misuse Death 10/7/2009 22 Male 169 lb 3/30/2010 United States
Primary
Secondary
Intentional Drug Misuse Death 10/7/2009 22 Male 169 lb 3/30/2010 United States
Primary
Secondary
Pain Other Serious 1/1/2009 40 Female 210 lb 4/5/2010 Physician United States
Primary
Concomitant
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 4/26/2010 Physician Finland
Primary
Concomitant
Suicide Attempt Other Serious Male 4/28/2010 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/1/2004 49 Male 185 lb 5/13/2010 United States
Primary
Concomitant
Hallucination 2/24/2010 52 Female 4/19/2010 Physician United States
Primary
Concomitant
Pneumonia Aspiration Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 35 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Pneumonia Hospitalization 33 Male 5/20/2010 Other Health Professional Netherlands
Primary
Secondary
Concomitant
Oral Pain Other Serious 4/20/2010 53 Female 5/21/2010 Pharmacist United States
Primary
Concomitant
Serotonin Syndrome Death 38 Male 5/28/2010 Physician Australia
Primary
Interacting
Serotonin Syndrome Death 34 Male 5/28/2010 Physician Australia
Primary
Interacting
Serotonin Syndrome Death 41 Male 5/28/2010 Physician Australia
Primary
Interacting
Pain Other Serious Male 6/1/2010
Primary
Secondary
Concomitant
Visual Impairment Other Serious 1 6/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Pneumonia Staphylococcal Hospitalization 48 Male 6/14/2010 Other Health Professional United States
Primary
Concomitant
Pneumonia Staphylococcal Hospitalization 48 Male 6/22/2010 Other Health Professional United States
Primary
Concomitant
Serotonin Syndrome Death 22 Male 6/22/2010
Primary
Secondary
Serotonin Syndrome Death 37 Male 6/22/2010
Primary
Secondary
Serotonin Syndrome Death 38 Male 6/24/2010
Primary
Secondary
Serotonin Syndrome Death 23 Male 6/24/2010
Primary
Secondary
Serotonin Syndrome Death 34 Male 6/24/2010
Primary
Secondary
Serotonin Syndrome Death 38 Male 6/24/2010
Primary
Secondary
Serotonin Syndrome Death 41 Male 6/24/2010
Primary
Secondary
Off Label Use Other Serious 1/1/2010 52 Male 6/24/2010 Physician United States
Primary
Concomitant
Poor Quality Drug Administered 1/9/2010 54 Male 170 lb 7/1/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 1 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 3 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 1 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 9 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 4 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 2 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Potentiating Drug Interaction Other Serious 1 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Visual Impairment Other Serious 1 7/2/2010 Other Health Professional United Kingdom
Primary
Secondary
Wound Dehiscence Other Serious 1/1/2000 34 Male 7/7/2010 United States
Primary
Secondary
Concomitant
Pulmonary Congestion Death 38 Male 7/6/2010 Other Health Professional Denmark
Primary
Concomitant
Suicide Attempt Other Serious 5/1/2007 49 Male 7/28/2010 Lawyer United States
Primary
Concomitant
Periorbital Haematoma Other Serious Female 102 lb 8/12/2010 Consumer United States
Primary
Concomitant
Idiopathic Thrombocytopenic Purpura Hospitalization 6/2/2010 30 Female 171 lb 8/12/2010 Physician United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 8/30/2010 United States
Primary
Secondary
Concomitant
Treatment Noncompliance Other Serious 5/10/2010 39 Male 187 lb 9/16/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 9/16/2010 Physician Finland
Primary
Concomitant
Pancreatitis Other Serious 7/6/2008 42 Female 280 lb 9/20/2010 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 11/19/1999 44 Female 181 lb 9/20/2010 United States
Primary
Concomitant
Obesity Hospitalization 6/1/2006 51 Male 250 lb 9/20/2010 United States
Primary
Concomitant
Treatment Noncompliance Other Serious 5/10/2010 39 Male 187 lb 9/27/2010 Other Health Professional United Kingdom
Primary
Concomitant
Urinary Incontinence Other Serious 12/1/2006 43 Female 10/4/2010 United States
Primary
Secondary
Concomitant
Somnambulism Other Serious Female 10/8/2010 Lawyer United States
Primary
Secondary
Somnambulism Death 11/22/2009 73 Female 10/8/2010 Lawyer United States
Primary
Interacting
Suspiciousness Hospitalization 11/22/2009 73 Female 10/8/2010 Consumer
Primary
Secondary
Drug Toxicity Other Serious 37 Male 10/11/2010
Primary
Secondary
Somnambulism Other Serious 11/22/2009 73 Female 10/11/2010 Consumer United States
Primary
Secondary
Sepsis Other Serious 1/1/2007 49 Male 10/13/2010 Consumer United States
Primary
Secondary
Concomitant
Rash Hospitalization Male 10/15/2010 Pharmacist United States
Primary
Concomitant
Wound Dehiscence Other Serious 1/1/2000 34 Male 10/19/2010 United States
Primary
Secondary
Concomitant
Withdrawal Syndrome Other Serious 1/1/2010 35 Male 159 lb 10/21/2010 Other Health Professional United Kingdom
Primary
Concomitant
Drug Toxicity Death 37 Male 10/22/2010 Other Health Professional Australia
Primary
Secondary
Weight Decreased Other Serious 1/1/2009 50 Male 291 lb 10/22/2010 Consumer United States
Primary
Concomitant
Vomiting Other Serious 5/22/2002 64 Male 185 lb 10/26/2010 United States
Primary
Concomitant
Drug Toxicity Death 37 Male 10/27/2010 United Kingdom
Primary
Secondary
Withdrawal Syndrome Other Serious 1/1/2010 35 Male 159 lb 11/3/2010 Other Health Professional United Kingdom
Primary
Concomitant
Suspiciousness Hospitalization 11/22/2009 73 Female 11/5/2010 Consumer
Primary
Secondary
Vomiting Other Serious 5/22/2002 64 Male 185 lb 12/14/2010 United States
Primary
Concomitant
Hypersomnia Other Serious 5/21/2008 41 Female 220 lb 4/26/2010 Physician Finland
Primary
Concomitant
Drug Interaction Death 22 Male 12/16/2010 Other Health Professional Australia
Primary
Secondary
Drug Interaction Death 22 Male 12/22/2010 Other Health Professional Australia
Primary
Interacting
Drug Prescribing Error Death 33 Male 12/23/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Drug Interaction Death 33 Male 12/27/2010 Other Health Professional Australia
Primary
Interacting
Thrombocytosis Other Serious 41 Male 12/28/2010 Other Health Professional Netherlands
Primary
Concomitant
Protein Total Decreased Hospitalization 6/5/2010 40 Male 210 lb 12/7/2010 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 62 Male 1/5/2011 Other Health Professional United States
Primary
Secondary
Cardiac Arrest Death 1/1/2009 62 Male 1/7/2011 Physician United States
Primary
Secondary
Hepatic Steatosis Hospitalization 1/1/2005 39 Male 1/10/2011 Pharmacist United States
Primary
Secondary
Concomitant
Sepsis Death 56 Female 1/17/2011 Physician United States
Primary
Concomitant
Convulsion Other Serious 12/1/2006 43 Female 1/18/2011 Physician United States
Primary
Secondary
Concomitant
Toxicity To Various Agents Death 45 Female 1/19/2011 Physician United States
Primary
Secondary
Toxicity To Various Agents Other Serious 3/9/2010 63 Female 1/19/2011 Other Health Professional United Kingdom
Primary
Secondary

Drug Data