Desflurane combined with Propofol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Tachycardia Life Threatening 2/1/2006 47 Male 121 lb 2/22/2006 Consumer France
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Required Intervention 2/1/2005 34 Male 2/21/2005 Physician United States
Primary
Concomitant
Urinary Casts Other Serious 23 Male 4/21/2006 United States
Primary
Concomitant
Urticaria Generalised Other Serious 23 Male 5/24/2006 Physician United States
Primary
Concomitant
Neuromuscular Block Prolonged Required Intervention 1/12/2006 67 Female 190 lb 4/10/2006 Pharmacist United States
Primary
Secondary
Concomitant
Respiratory Distress Other Serious 8/28/2005 16 Male 8/26/2006 Physician Canada
Primary
Concomitant
Troponin I Increased Other Serious 12/1/2002 17 Female 9/11/2006 Other Health Professional United States
Primary
Concomitant
Confusional State Hospitalization 79 Male 10/13/2006 Other Health Professional Australia
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 6/20/2006 0 Female 17 lb 10/25/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Arrest Life Threatening 6/20/2006 0 Female 17 lb 10/27/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 0 Female 5 lb 12/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Rhabdomyolysis Life Threatening 11/28/2006 Female 5 lb 1/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Unwanted Awareness During Anaesthesia Other Serious Male 1/23/2007
Primary
Secondary
Psychotic Disorder Other Serious Male 2/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Psychotic Disorder Other Serious Male 2/21/2007 Other Health Professional United Kingdom
Primary
Concomitant
Tachycardia Hospitalization 9/25/2006 54 Female 2/23/2007 Consumer France
Primary
Concomitant
Oxygen Saturation Decreased Life Threatening 10/24/2005 Male 165 lb 4/5/2007 Physician
Primary
Secondary
Concomitant
Radius Fracture Required Intervention 3/14/2007 Male 220 lb 4/19/2007 Pharmacist United States
Primary
Secondary
Concomitant
Laryngospasm Other Serious 6/8/2007 41 Female 7/31/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Syncope Other Serious 14 Male 11/21/2007 Physician United Kingdom
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 8/6/2007 44 Female 12/3/2007 Consumer France
Primary
Secondary
Concomitant
Post Procedural Discharge Other Serious 9/26/2007 Female 2/1/2008 Other Health Professional France
Primary
Secondary
Concomitant
Respiratory Failure Death 76 Female 104 lb 2/11/2008 Physician New Zealand
Primary
Concomitant
Psychotic Disorder Other Serious 33 Female 5/16/2008
Primary
Secondary
Concomitant
Tumour Lysis Syndrome Other Serious 8 Male 60 lb 5/22/2008
Primary
Secondary
Concomitant
Tachycardia Hospitalization 5/10/2008 69 Female 5/28/2008 Belgium
Primary
Concomitant
Tumour Lysis Syndrome Hospitalization 1/1/2008 8 Male 60 lb 6/26/2008 Other Health Professional Germany
Primary
Concomitant
Tachycardia Hospitalization 5/10/2008 69 Female 6/26/2008 Belgium
Primary
Concomitant
Hepatotoxicity Hospitalization 1 Male 10/15/2008 Physician United States
Primary
Secondary
Concomitant
Right Ventricular Failure Life Threatening 18 Female 132 lb 1/29/2009 Physician United States
Primary
Secondary
Concomitant
Spinal Osteoarthritis Hospitalization 1/15/2009 47 Female 159 lb 3/10/2009 Other Health Professional United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 1/15/2009 47 Female 159 lb 3/18/2009 Other Health Professional United States
Primary
Concomitant
Opisthotonus Other Serious 26 Male 4/2/2009
Primary
Secondary
Tremor Other Serious 26 Male 4/3/2009 United States
Primary
Secondary
Concomitant
Procedural Pain Other Serious 16 Male 378 lb 4/24/2009 Other Health Professional United States
Primary
Concomitant
Oropharyngeal Spasm Other Serious 26 Male 7/9/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Weight Decreased 12/3/2007 46 Female 12/8/2008 Physician United States
Primary
Concomitant
Tachycardia Other Serious 52 Female 137 lb 8/18/2009
Primary
Secondary
Muscular Weakness Other Serious 52 Female 137 lb 8/28/2009 Other Health Professional United States
Primary
Concomitant
Pulse Abnormal Hospitalization 9/7/2009 Male 102 lb 9/9/2009 United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 41 Male 10/23/2009 Physician China
Primary
Concomitant
Multi-organ Failure Life Threatening 43 Female 154 lb 12/4/2009 Other Health Professional Belgium
Primary
Concomitant
Sleep Disorder Other Serious 8/11/2009 61 Female 150 lb 12/30/2009 Pharmacist United States
Primary
Concomitant
Multi-organ Failure Disability 43 Female 154 lb 2/4/2010 Other Health Professional Belgium
Primary
Concomitant
Multi-organ Failure Other Serious 43 Female 154 lb 2/16/2010 Physician Belgium
Primary
Concomitant
Ventricular Fibrillation Other Serious 71 Male 187 lb 2/23/2010 Other Health Professional United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/26/2010 Other Health Professional United States
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 3/26/2010
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 3/29/2010 Physician United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7 Male 65 lb 4/9/2010 Other Health Professional United Kingdom
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 4/4/2010 United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7 Male 65 lb 4/14/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 44 Female 4/15/2010 Other Health Professional United States
Primary
Secondary
Respiratory Distress Life Threatening 4/19/2010 Other Health Professional United Kingdom
Primary
Secondary
Drug Tolerance Other Serious 16 Male 172 lb 4/20/2010
Primary
Secondary
Respiratory Distress Life Threatening 7 Male 65 lb 4/13/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7 Male 65 lb 4/13/2010
Primary
Secondary
Serotonin Syndrome Other Serious 44 Female 4/15/2010 United States
Primary
Secondary
Concomitant
Respiratory Distress Life Threatening 7 Male 4/20/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Respiratory Failure Life Threatening 7 Male 66 lb 5/4/2010 Other Health Professional United Kingdom
Primary
Secondary
Tracheostomy Life Threatening 7 Male 65 lb 4/29/2010 Consumer United Kingdom
Primary
Secondary
Unresponsive To Stimuli Other Serious 44 Female 5/10/2010 Consumer United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 44 Female 5/20/2010 Physician United States
Primary
Secondary
Concomitant
Tubulointerstitial Nephritis Required Intervention 23 Female 133 lb 6/15/2010 United States
Primary
Secondary
Concomitant
Jaundice Cholestatic Hospitalization Female 214 lb 6/17/2010 Other Health Professional Australia
Primary
Secondary
Concomitant
Hypotension Required Intervention 8/8/2008 64 Male 188 lb 7/9/2010 Physician Philippines
Primary
Secondary
Concomitant
Electrocardiogram St Segment Depression Required Intervention 5/21/2008 51 Female 152 lb 7/9/2010 Physician Philippines
Primary
Concomitant
Electrocardiogram St Segment Depression Required Intervention 5/21/2008 51 Female 152 lb 7/26/2010 Physician Philippines
Primary
Concomitant
Respiratory Depression Death 26 Female 130 lb 11/24/2010 Other Health Professional South Africa
Primary
Concomitant
Respiratory Depression Death 26 Female 130 lb 12/9/2010
Primary
Concomitant
Muscle Spasms Other Serious 54 Female 128 lb 12/16/2010 Other Health Professional Germany
Primary
Secondary
Concomitant
Ventricular Tachycardia Hospitalization Male 132 lb 12/28/2010 Consumer France
Primary
Secondary
Concomitant
Coronary Artery Disease Hospitalization 43 Female 165 lb 1/14/2011 Consumer United States
Primary
Concomitant
Coronary Artery Disease Hospitalization 43 Female 165 lb 1/14/2011 United States
Primary
Concomitant
Pulmonary Oedema Hospitalization Male 132 lb 2/4/2011 Consumer France
Primary
Secondary
Concomitant
Anaphylactic Reaction Life Threatening 2/17/2011 56 Female 108 lb 3/18/2011 Other Health Professional United Kingdom
Primary
Concomitant
Insomnia Hospitalization 36 Male 3/21/2011 Consumer Germany
Primary
Concomitant
Renal Failure Hospitalization Male 258 lb 3/30/2011 Consumer United States
Primary
Concomitant
Unevaluable Event Death Male 258 lb 3/30/2011 Other Health Professional United States
Primary
Concomitant
Drug Interaction Other Serious 1/7/2011 36 Male 4/1/2011 Consumer Germany
Primary
Secondary
Interacting
Injury Hospitalization 64 Male 250 lb 4/8/2011 Consumer United States
Primary
Concomitant
Anxiety Other Serious 61 Male 177 lb 5/17/2011 Lawyer United States
Primary
Concomitant
Fear Other Serious 9/1/2006 86 Male 172 lb 5/19/2011 Lawyer United States
Primary
Concomitant
Diabetic Ketoacidosis Hospitalization 8/1/2008 43 Male 166 lb 6/30/2011 Physician United States
Primary
Secondary
Concomitant
Torsade De Pointes Hospitalization 11 Male 79 lb 7/2/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Hepatic Function Abnormal Other Serious 69 Male 7/22/2011 Physician United States
Primary
Concomitant
Disseminated Intravascular Coagulation Other Serious 31 Male 7/22/2011 Physician United States
Primary
Concomitant
Cardiac Disorder Death 23 Male 7/22/2011 Physician United States
Primary
Concomitant
Eye Disorder Other Serious 49 Male 7/22/2011 Physician United States
Primary
Concomitant
Neuromuscular Block Prolonged Hospitalization 22 Female 101 lb 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Neuromuscular Block Prolonged Hospitalization 30 Female 110 lb 8/3/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Stress Cardiomyopathy Hospitalization 47 Female 140 lb 8/18/2011 Other Health Professional Canada
Primary
Secondary
Concomitant
Localised Infection Other Serious 8/1/2008 43 Male 166 lb 8/29/2011 Lawyer United States
Primary
Secondary
Concomitant
Gait Disturbance Other Serious 1/7/2011 36 Male 198 lb 9/29/2011 Physician Germany
Primary
Secondary
Concomitant
Interacting
Hypoventilation Hospitalization 42 Male 11/8/2011 Physician United States
Primary
Secondary
Heart Rate Increased Other Serious 53 Female 143 lb 12/23/2011 Other Health Professional United States
Primary
Concomitant
Hyperthermia Malignant Other Serious 38 Female 1/4/2012 Other Health Professional Germany
Primary
Secondary
Cogwheel Rigidity Other Serious 64 Male 2/13/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 64 Male 2/14/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Condition Aggravated Other Serious 64 Male 2/15/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Dysphagia Other Serious 64 Male 2/22/2012 Physician Australia
Primary
Secondary
Concomitant
Aphasia Other Serious 44 Female 2/28/2012 Physician United States
Primary
Secondary
Concomitant
Parkinson's Disease Other Serious 64 Male 3/12/2012 Other Health Professional Australia
Primary
Secondary
Concomitant
Cardiac Arrest Life Threatening 3/27/2012 74 Male 4/27/2012 Physician France
Primary
Secondary
Circulatory Collapse Life Threatening 3/27/2012 74 Male 4/27/2012 Physician France
Primary
Secondary
Cardiac Arrest Life Threatening 1/1/2012 74 Male 5/2/2012 Physician France
Primary
Secondary
Serotonin Syndrome Other Serious 5/25/2012 Physician United States
Primary
Secondary
Concomitant
Bone Marrow Disorder Hospitalization 8/1/2008 43 Male 166 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 68 Female 185 lb 5/29/2012 United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization Female 161 lb 5/29/2012 Physician United States
Primary
Secondary
Concomitant
Encephalopathy Hospitalization Female 161 lb 5/30/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Life Threatening 68 Female 185 lb 5/24/2012 Physician United States
Primary
Secondary
Concomitant
Unresponsive To Stimuli Other Serious 68 Female 5/23/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Encephalopathy Other Serious 4/26/2012 55 Female 161 lb 5/31/2012 Consumer United States
Primary
Secondary
Concomitant
Intracranial Pressure Increased Other Serious 4/26/2012 55 Female 161 lb 5/31/2012 Other Health Professional United States
Primary
Secondary
Concomitant
Nephrolithiasis Hospitalization 2/1/2010 63 Male 6/12/2012 Lawyer United States
Primary
Concomitant
Methaemoglobinaemia Other Serious 48 Female 6/4/2012 Physician United States
Primary
Concomitant
Serotonin Syndrome Other Serious 68 Female 185 lb 7/12/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 68 Female 185 lb 7/13/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 68 Female 185 lb 7/13/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Hospitalization 68 Female 185 lb 7/16/2012 Physician United States
Primary
Secondary
Concomitant
Serotonin Syndrome Other Serious 68 Female 185 lb 8/7/2012 Physician United States
Primary
Secondary
Hyperreflexia Other Serious 68 Female 185 lb 8/8/2012 Physician United States
Primary
Secondary
Concomitant
Interacting
Asthenia Hospitalization 8/1/2008 43 Male 166 lb 8/14/2012 Physician United States
Primary
Secondary
Concomitant
Drug Interaction Other Serious 68 Female 185 lb 8/14/2012 Physician United States
Primary
Concomitant
Interacting
Unresponsive To Stimuli Other Serious 68 Female 185 lb 8/2/2012 Physician United States
Primary
Secondary
Concomitant
Agitation Other Serious 68 Female 185 lb 7/25/2012 Physician United States
Primary
Secondary
Concomitant
Deep Vein Thrombosis Other Serious 8/1/2008 43 Male 166 lb 8/23/2012 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Life Threatening 2/17/2011 56 Female 108 lb 5/28/2013 Other Health Professional Gb
Primary
Concomitant
Renal Failure Acute Other Serious 9/12/2007 72 Male 170 lb 12/13/2012 Other Health Professional Us
Primary
Concomitant
Methaemoglobinaemia Other Serious 48 Female 6/14/2013 Physician Us
Primary
Concomitant
Unresponsive To Stimuli Other Serious 68 Female 185 lb 9/7/2012 Physician Us
Primary
Secondary
Concomitant
Ventricular Hypokinesia Life Threatening 53 Male 141 lb 10/10/2012 Physician Ca
Primary
Secondary
Concomitant
Post Procedural Haemorrhage Hospitalization 9/11/2012 33 Female 234 lb 11/6/2012 Physician Us
Primary
Concomitant
Post Procedural Complication 1/8/2011 75 Male 1/8/2011 Us
Primary
Secondary
Concomitant
Vomiting Other Serious 47 Male 143 lb 12/10/2012 Other Health Professional Kr
Primary
Secondary
Concomitant
Tremor Other Serious 7/6/2012 77 Male 132 lb 12/3/2012 Physician Jp
Primary
Concomitant
Amnesia Other Serious 45 Male 185 lb 11/16/2012 Physician Gb
Primary
Secondary
Anaesthetic Complication Neurological Other Serious NotSpecified 1/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Decreased Activity Hospitalization NotSpecified 1/15/2013 Other Health Professional De
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization 5/16/2010 43 Female 169 lb 5/14/2013 Lawyer Us
Primary
Secondary
Concomitant
Methaemoglobinaemia Other Serious 48 Female 3/19/2013 Other Health Professional Us
Primary
Concomitant
Premature Labour Hospitalization 23 Female 152 lb 4/24/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Premature Baby Other Serious NotSpecified 4/24/2013 Other Health Professional Tr
Primary
Secondary
Concomitant
Sinus Tachycardia Hospitalization Female 4/24/2013 Us
Primary
Concomitant
Drug Interaction Other Serious 51 Male 5/1/2013 Other Health Professional De
Primary
Concomitant
Interacting
Atrioventricular Block Complete Hospitalization 80 Female 117 lb 6/7/2013 Other Health Professional Kr
Primary
Secondary
Concomitant
Hypotension 63 Male 6/7/2013 It
Primary
Secondary
Concomitant
Hypotension Other Serious 35 Female 249 lb 8/22/2013 Physician Us
Primary
Concomitant
Interacting

Drug Data