Depakote combined with Topamax

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 7/23/2001 24 Female 175 lb 1/10/2006 Lawyer United States
Primary
Concomitant
Mental Disorder Hospitalization 16 Female 1/27/2006 Consumer United States
Primary
Concomitant
Wrong Technique In Drug Usage Process Other Serious 2/16/2006 10 Female 2/28/2006 Consumer Korea, Republic Of
Primary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Intentional Drug Misuse Other Serious 1/1/2006 10 Female 3/24/2006 Consumer Korea, Republic Of
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 3/23/2006 United States
Primary
Concomitant
Vitreous Detachment Other Serious 8/1/2005 Male 4/17/2006 Consumer United States
Primary
Concomitant
Hiv Infection Death 9/1/1992 Male 119 lb 5/1/2006 United States
Primary
Concomitant
Loss Of Consciousness Death 9/1/1992 Male 119 lb 5/3/2006 United States
Primary
Concomitant
Loss Of Consciousness Death 9/1/1992 Male 119 lb 5/4/2006 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 60 Female 121 lb 5/10/2006 Physician United States
Primary
Concomitant
Myocardial Infarction Hospitalization 1/1/1999 44 Male 181 lb 5/15/2006 Physician United States
Primary
Concomitant
Paralysis Other Serious 1/1/2004 45 Female 104 lb 3/15/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 60 Female 180 lb 5/31/2006 Physician United States
Primary
Secondary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/7/2006 Physician Brazil
Primary
Concomitant
Weight Increased Other Serious 7/1/2003 20 Female 101 lb 4/18/2006 Physician United States
Primary
Secondary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/14/2006 United States
Primary
Concomitant
Screaming Hospitalization 6/14/2006 Male 34 lb 6/18/2006 United States
Primary
Concomitant
Pyrexia Hospitalization 1/1/2006 18 Female 121 lb 6/22/2006 Physician Brazil
Primary
Concomitant
Convulsion Hospitalization 1/29/2006 Male 145 lb 2/20/2006 Other Health Professional United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 6/30/2006 United States
Primary
Concomitant
Upper Respiratory Tract Infection Hospitalization 2/11/2006 56 Male 215 lb 7/11/2006 Physician United States
Primary
Concomitant
Blood Glucose Increased 58 Male 7/21/2006 Consumer United States
Primary
Secondary
Concomitant
Pneumonia 1/1/2006 54 Female 166 lb 7/12/2006 Consumer United States
Primary
Concomitant
Swelling Face Other Serious 64 Male 182 lb 7/27/2006 United States
Primary
Concomitant
Somnolence 3/9/2006 12 Male 221 lb 7/12/2006 Consumer United States
Primary
Concomitant
Scoliosis Death 12/16/2004 61 Female 119 lb 8/1/2006 United States
Primary
Concomitant
Loss Of Consciousness Death 9/1/1992 Male 119 lb 8/8/2006 United States
Primary
Concomitant
Dehydration Hospitalization 5/21/2006 Female 300 lb 7/31/2006 Other Health Professional United States
Primary
Concomitant
Rash Generalised Other Serious 6/1/2006 Male 179 lb 8/18/2006 Physician United States
Primary
Concomitant
Swelling Face Other Serious 1/1/2006 64 Female 182 lb 8/28/2006 Physician United States
Primary
Secondary
Sudden Death Death 2/13/2006 Male 119 lb 9/1/2006 United States
Primary
Concomitant
Myocardial Infarction Death 12/16/2004 61 Female 119 lb 9/6/2006 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 6/1/2005 58 Male 7/14/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 9/29/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 10/9/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Dysphonia 1/1/2006 62 Male 10/30/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 11/3/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Otorrhoea Other Serious 10/12/2006 54 Female 209 lb 11/10/2006 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 8/1/2005 12 Female 73 lb 8/18/2006 Physician United States
Primary
Concomitant
Convulsion Other Serious 35 Male 11/15/2006 Physician United States
Primary
Concomitant
Rash Generalised Other Serious 6/1/2006 Male 179 lb 11/21/2006 Physician United States
Primary
Concomitant
Treatment Noncompliance Other Serious 1/1/2006 26 Female 348 lb 11/14/2006 United States
Primary
Secondary
Concomitant
Psychotic Disorder Hospitalization 4/13/2004 11 Female 139 lb 11/17/2006 Physician United States
Primary
Concomitant
Hepatic Enzyme Increased Other Serious 11/1/2005 53 Female 8/18/2006 United States
Primary
Concomitant
Hepatic Failure Life Threatening 5/18/2004 45 Female 165 lb 8/18/2006 Physician United States
Primary
Secondary
Psychotic Disorder Hospitalization 4/13/2004 11 Male 139 lb 12/6/2006 Physician United States
Primary
Concomitant
Sudden Death Death 2/13/2006 Male 119 lb 12/18/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious 10/2/2006 46 Female 12/14/2006 United States
Primary
Secondary
Concomitant
Akinesia 12/17/2005 16 Male 12/29/2006 Consumer United States
Primary
Concomitant
Somnolence 55 Male 174 lb 12/29/2006 Consumer United States
Primary
Concomitant
Enuresis 31 Female 12/29/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 1/16/2007 United States
Primary
Secondary
Concomitant
Theft Other Serious 1/1/2002 Male 1/18/2007 Consumer United States
Primary
Concomitant
Suicidal Ideation Life Threatening 9/30/1999 Female 115 lb 1/16/2007 Consumer United States
Primary
Concomitant
Metabolic Disorder Other Serious 1/1/2000 Male 260 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/2006 Female 10/10/2006 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 1/1/2007 52 Female 223 lb 1/26/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 11/1/2006 53 Female 2/2/2007 Consumer United States
Primary
Concomitant
Pain Hospitalization 1/16/2007 49 Female 115 lb 1/29/2007 Other Health Professional United States
Primary
Concomitant
Tremor Other Serious 11/1/2006 53 Female 2/7/2007 Consumer United States
Primary
Concomitant
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 2/10/2007 United States
Primary
Secondary
Concomitant
Otorrhoea Other Serious 10/12/2006 54 Female 209 lb 2/14/2007 Physician United States
Primary
Concomitant
Otorrhoea Other Serious 10/12/2006 54 Female 209 lb 2/21/2007 Physician United States
Primary
Concomitant
Suicidal Ideation Other Serious 12/1/2001 Female 134 lb 2/28/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Pharmaceutical Product Complaint 7/14/2006 28 Female 2/28/2007 Consumer United States
Primary
Concomitant
Dizziness Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Drug Exposure During Pregnancy Male 6 lb 2/28/2007 Other Health Professional United States
Primary
Concomitant
Vision Blurred 18 Male 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Essential Hypertension Hospitalization 5/6/2006 Male 3/1/2007 Physician United States
Primary
Concomitant
Myocardial Infarction Other Serious 12/16/2004 Female 119 lb 3/2/2007 Lawyer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 8/1/2004 34 Female 200 lb 12/8/2006 Physician United States
Primary
Concomitant
Diabetes Mellitus Required Intervention 12/16/2002 51 Male 8/21/2004 Physician United States
Primary
Concomitant
Tremor Other Serious 11/1/2006 53 Female 3/26/2007 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Required Intervention 40 Female 8/21/2004 Physician United States
Primary
Concomitant
Cataract Required Intervention 5/1/2004 61 Female 8/25/2005 Physician United States
Primary
Secondary
Concomitant
Weight Increased Required Intervention 7/13/2005 34 Female 243 lb 8/17/2006 Physician United States
Primary
Concomitant
Suicidal Ideation Death 8/4/2006 53 Male 178 lb 8/8/2006 Other Health Professional United States
Primary
Concomitant
Insomnia 6/1/2006 52 Female 1/12/2007 Pharmacist United States
Primary
Concomitant
Tremor Other Serious 12/1/2006 29 Female 4/19/2007 Consumer United States
Primary
Interacting
Weight Decreased Other Serious 4/1/2006 59 Male 180 lb 4/18/2007 United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Death 2/22/2007 41 Male 4/12/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2001 26 Male 337 lb 5/15/2007 Consumer United States
Primary
Secondary
Concomitant
Sudden Cardiac Death Hospitalization 41 Male 140 lb 5/18/2007 Consumer United States
Primary
Concomitant
Suicide Attempt Hospitalization 7/1/2006 33 Female 330 lb 5/24/2007 United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 30 Male 220 lb 3/28/2007 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 3/28/2007 United States
Primary
Secondary
Concomitant
Hypospadias Congenital Anomaly 4/1/2007 Male 6/1/2007 Physician United States
Primary
Concomitant
Status Epilepticus Hospitalization 1/1/2006 Female 6/21/2007 Consumer United States
Primary
Concomitant
Spinal Osteoarthritis Hospitalization 4/2/2003 30 Female 6/22/2007 Physician United States
Primary
Concomitant
Nephrogenic Fibrosing Dermopathy Death 15 Male 77 lb 6/27/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/24/2000 32 Female 220 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Vomiting Other Serious 6/1/2004 41 Female 135 lb 7/13/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Tremor Other Serious 6/19/2007 6 Male 46 lb 7/26/2007 Consumer Brazil
Primary
Concomitant
Breast Cancer Other Serious 10/2/2003 59 Female 165 lb 7/5/2007 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 124 lb 8/8/2007 Consumer United States
Primary
Concomitant
Myelopathy Other Serious 44 Male 122 lb 8/20/2007 Pharmacist United States
Primary
Concomitant
Weight Increased Hospitalization 1/1/1997 33 Female 176 lb 9/12/2007 Consumer United States
Primary
Concomitant
Ureteral Disorder Congenital Anomaly Male 9/14/2007 Physician United States
Primary
Concomitant
Type 1 Diabetes Mellitus 1/1/2002 15 Male 9/17/2007 United States
Primary
Secondary
Concomitant
Ketoacidosis Other Serious 1/1/1999 37 Female 127 lb 9/18/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2004 24 Female 181 lb 9/18/2007 Physician United States
Primary
Concomitant
Dyskinesia 7/1/2007 18 Female 9/19/2007 Other Health Professional United States
Primary
Concomitant
Tremor 12/1/2006 29 Female 9/19/2007 Consumer United States
Primary
Secondary
Weight Increased 51 Female 188 lb 9/19/2007 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 5/31/2007 23 Female 130 lb 9/19/2007 Physician United States
Primary
Concomitant
Weight Increased Hospitalization 3/1/2007 Female 324 lb 9/24/2007 Other Health Professional United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 9/25/2007 Lawyer United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Death 1/1/2004 15 Male 77 lb 9/26/2007 Consumer United States
Primary
Secondary
Concomitant
Trigeminal Neuralgia Other Serious 7/21/2003 38 Female 142 lb 10/5/2007 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 44 Female 10/16/2007 Consumer United States
Primary
Secondary
Concomitant
Ureteral Disorder Congenital Anomaly Male 10/16/2007 Consumer United States
Primary
Concomitant
Pharmaceutical Product Complaint 9/7/2006 30 Female 10/25/2007 Consumer United States
Primary
Concomitant
Urinary Tract Infection Other Serious 6/21/2007 19 Female 250 lb 11/1/2007 United States
Primary
Concomitant
Ichthyosis Hospitalization 0 Female 4 lb 11/13/2007 Physician Italy
Primary
Secondary
Weight Decreased Hospitalization 1/1/2007 Female 280 lb 11/8/2007 Consumer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 12/7/2007 Lawyer United States
Primary
Concomitant
Stevens-johnson Syndrome Other Serious 4/1/2005 Female 136 lb 12/26/2007 Lawyer United States
Primary
Concomitant
Decreased Appetite Other Serious 7/1/2007 7 2/4/2008 Consumer China
Primary
Concomitant
Weight Decreased Other Serious 1/1/2007 Male 124 lb 2/13/2008 Consumer United States
Primary
Concomitant
Intelligence Test Abnormal Other Serious 1/1/2004 9 Female 2/11/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/24/2000 32 Female 220 lb 2/26/2008 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2008 Female 84 lb 3/21/2008 Consumer United States
Primary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Dizziness Other Serious 3/6/2008 51 Female 168 lb 3/13/2008 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 3/17/2008 51 Female 168 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Hospitalisation Other Serious Female 4/7/2008 Physician United States
Primary
Concomitant
Death Other Serious 4/6/2008 Male 4/21/2008 Physician United States
Primary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 4/29/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 15 Male 77 lb 5/5/2008 Lawyer United States
Primary
Secondary
Concomitant
Nephrogenic Systemic Fibrosis Other Serious 1/1/2004 5/6/2008 Other Health Professional Germany
Primary
Secondary
Concomitant
Paralysis Other Serious 5/1/2008 59 Male 220 lb 5/9/2008 Consumer Brazil
Primary
Concomitant
Weight Fluctuation Other Serious Female 119 lb 5/7/2008 Physician United States
Primary
Secondary
Concomitant
Thyroid Mass Other Serious 1/1/2008 Female 226 lb 5/15/2008 United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Male 160 lb 6/4/2008 Other Health Professional United States
Primary
Concomitant
Gait Disturbance 7/1/2007 57 Male 5/5/2008 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 6/12/2008 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Mass Other Serious 1/1/2008 Female 226 lb 6/17/2008 United States
Primary
Concomitant
Tremor Other Serious 1/1/2007 Male 160 lb 6/18/2008 Other Health Professional United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/19/2008 Lawyer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 6/20/2008 Lawyer United States
Primary
Secondary
Concomitant
Renal Tubular Necrosis Other Serious 5/22/2008 53 Male 6/17/2008 Physician United States
Primary
Secondary
Concomitant
Xerosis Other Serious 1/1/2000 11 Male 77 lb 6/23/2008 Lawyer United States
Primary
Secondary
Concomitant
Thyroid Mass Other Serious 3/1/2008 Female 226 lb 6/27/2008 United States
Primary
Concomitant
Hypertension 12/12/2007 70 Male 5/6/2008 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2004 Female 205 lb 7/31/2008 Consumer United States
Primary
Concomitant
Toxic Epidermal Necrolysis Other Serious 10/16/2000 Male 134 lb 8/1/2008 Lawyer United States
Primary
Secondary
Concomitant
Ventricular Septal Defect Hospitalization 5/26/2004 Female 8/5/2008 Other Health Professional United States
Primary
Concomitant

Drug Data