Depakote combined with Rebif

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Pyrexia Other Serious 3/5/2006 30 Male 3/13/2006 United States
Primary
Concomitant
Vision Blurred Other Serious 3/5/2006 30 Male 3/30/2006 United States
Primary
Concomitant
Drug Interaction Other Serious 3/5/2006 30 Male 4/17/2006 Other Health Professional United States
Primary
Secondary
Vomiting Death 7/26/2006 54 Female 9/15/2006 United States
Primary
Secondary
Pancreatitis Life Threatening 9/27/2006 54 Female 200 lb 10/3/2006 Physician United States
Primary
Secondary
Vomiting Death 7/26/2006 54 Female 9/27/2006 United States
Primary
Secondary
Concomitant
Vomiting Death 7/26/2006 54 Female 10/2/2006 Consumer United States
Primary
Secondary
Thrombotic Thrombocytopenic Purpura Hospitalization 6/1/2006 59 Female 107 lb 10/23/2006 Physician United States
Primary
Concomitant
Status Epilepticus Other Serious 5/16/2006 45 Female 12/8/2006 Physician United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 3/4/2006 58 Male 12/12/2006 United States
Primary
Secondary
Concomitant
Viral Infection Life Threatening 3/3/2006 58 Male 12/22/2006 Other Health Professional United States
Primary
Secondary
Concomitant
Partial Seizures Other Serious 11/16/2006 55 Female 12/21/2006 Physician United States
Primary
Concomitant
Speech Disorder Life Threatening 3/3/2006 59 Male 1/29/2007 Pharmacist United States
Primary
Secondary
Concomitant
Pollakiuria Other Serious 1/15/2007 35 Female 200 lb 2/20/2007 United States
Primary
Secondary
Concomitant
Convulsion Other Serious 4/17/2006 48 Female 3/13/2007 United States
Primary
Concomitant
Suicide Attempt Hospitalization 2/4/2006 43 Female 3/13/2007 United States
Primary
Concomitant
Renal Failure Hospitalization 6/18/2006 45 Female 3/12/2007 United States
Primary
Secondary
Accidental Overdose Death 54 Female 3/19/2007 United States
Primary
Secondary
Renal Failure Hospitalization 6/18/2006 45 Female 6/4/2007 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2007 41 Female 110 lb 7/31/2007 Physician United States
Primary
Concomitant
Lacunar Infarction Hospitalization 7/8/2005 50 Male 8/13/2007 Physician United States
Primary
Concomitant
Convulsion Hospitalization 1/1/2007 64 Female 8/17/2007 United States
Primary
Concomitant
Vomiting Death 7/26/2006 54 Female 7/27/2007 United States
Primary
Secondary
Convulsion Hospitalization 1/1/2007 64 Female 10/9/2007 Physician United States
Primary
Secondary
Concomitant
Injection Site Pain Hospitalization 1/1/2007 55 Female 108 lb 11/30/2007 United States
Primary
Concomitant
Convulsion Hospitalization 1/1/2007 64 Female 12/12/2007 Physician United States
Primary
Secondary
Concomitant
Skin Necrosis Other Serious 2/28/2008 48 Female 147 lb 3/10/2008 Other Health Professional United States
Primary
Concomitant
Dizziness Other Serious 3/6/2008 51 Female 168 lb 3/13/2008 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 3/17/2008 51 Female 168 lb 3/27/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Uterine Leiomyoma Other Serious 1/1/2006 41 Female 162 lb 4/1/2008 United States
Primary
Concomitant
Viral Infection Hospitalization 11/1/2007 46 Female 5/1/2008 United States
Primary
Concomitant
Paraesthesia Hospitalization 5/1/2007 31 Female 95 lb 5/1/2008 United States
Primary
Concomitant
Multiple Sclerosis Hospitalization 5/28/2008 46 Female 7/9/2008 United States
Primary
Concomitant
Headache Hospitalization 2/26/2007 27 Female 7/16/2008 United States
Primary
Concomitant
Sinusitis Hospitalization 6/6/2008 49 Female 111 lb 7/16/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 50 Female 160 lb 9/2/2008 United States
Primary
Concomitant
Pain Hospitalization 8/28/2008 51 Female 145 lb 9/19/2008 Other Health Professional United States
Primary
Concomitant
Uterine Disorder Hospitalization 5/8/2008 58 Female 122 lb 9/19/2008 United States
Primary
Concomitant
Injection Site Reaction Hospitalization 1/1/2007 55 Female 108 lb 10/3/2008 Consumer United States
Primary
Concomitant
Recurrent Cancer Other Serious 5/1/2008 55 Male 146 lb 10/3/2008 United States
Primary
Concomitant
Uterine Disorder Hospitalization 5/8/2008 58 Female 121 lb 10/6/2008 Other Health Professional United States
Primary
Concomitant
Rash Other Serious 8/11/2008 49 Female 10/10/2008 United States
Primary
Concomitant
Multiple Sclerosis Other Serious 8/1/2008 22 Female 185 lb 10/28/2008 United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 8/23/2008 51 Female 11/4/2008 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 5/1/2008 44 Female 185 lb 11/24/2008 United States
Primary
Concomitant
Uterine Leiomyoma Other Serious 1/1/2006 40 Female 163 lb 11/25/2008 Physician United States
Primary
Concomitant
Pneumonia Hospitalization 10/1/2008 57 Female 108 lb 12/1/2008 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 9/16/2008 28 Male 130 lb 12/1/2008 Physician United States
Primary
Concomitant
Treatment Noncompliance Hospitalization 3/30/2008 26 Female 201 lb 12/11/2008 Other Health Professional United States
Primary
Concomitant
Tremor Hospitalization 9/23/2008 51 Female 12/22/2008 Physician United States
Primary
Concomitant
Micturition Urgency Hospitalization 2/5/2009 36 Female 119 lb 2/18/2009 Consumer United States
Primary
Concomitant
Syncope Hospitalization 2/3/2009 36 Female 119 lb 2/27/2009 Physician United States
Primary
Concomitant
Prostate Cancer Hospitalization 2/1/2009 59 Male 3/25/2009 United States
Primary
Concomitant
Surgical Procedure Repeated Hospitalization 6/6/2008 49 Female 110 lb 4/3/2009 United States
Primary
Concomitant
Disease Recurrence Other Serious 5/1/2008 55 Male 146 lb 4/13/2009 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/7/2009 49 Female 4/21/2009 United States
Primary
Concomitant
Convulsion Hospitalization 3/22/2009 17 Male 4/27/2009 Consumer Brazil
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/7/2009 49 Female 5/7/2009 United States
Primary
Concomitant
Pituitary Tumour Other Serious 4/1/2009 51 Female 5/13/2009 United States
Primary
Concomitant
Personality Change Hospitalization 10/20/2008 29 Female 6/22/2009 Physician United States
Primary
Concomitant
Sinusitis Hospitalization 6/6/2008 49 Female 110 lb 6/23/2009 Physician United States
Primary
Concomitant
Rash Papular Other Serious 5/1/2008 55 Male 146 lb 7/1/2009 Physician United States
Primary
Concomitant
Multiple Sclerosis Other Serious 49 Female 7/14/2009 United States
Primary
Concomitant
Diabetes Mellitus Other Serious 11/1/2008 55 Female 227 lb 7/27/2009 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 7/30/2009 48 Male 8/17/2009 Consumer Brazil
Primary
Concomitant
Musculoskeletal Discomfort Hospitalization 9/14/2009 36 Female 10/9/2009 United States
Primary
Concomitant
White Blood Cell Count Decreased Hospitalization 10/1/2009 41 Female 161 lb 11/4/2009 United States
Primary
Concomitant
Sensation Of Pressure Hospitalization 9/14/2009 36 Female 11/18/2009 United States
Primary
Concomitant
Osteonecrosis Other Serious 10/1/2009 40 Male 130 lb 11/18/2009 Consumer United States
Primary
Concomitant
Prostate Cancer Hospitalization 2/1/2009 59 Male 11/30/2009 Other Health Professional United States
Primary
Concomitant
Pituitary Tumour Other Serious 4/1/2009 51 Female 185 lb 12/17/2009 Physician United States
Primary
Concomitant
Drug Exposure During Pregnancy Other Serious 1/22/2010 21 Female 2/1/2010 Consumer United States
Primary
Concomitant
Visual Impairment Other Serious 60 Female 245 lb 2/24/2010 Consumer United States
Primary
Concomitant
Weight Increased Hospitalization 3/18/2010 39 Female 3/25/2010 United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/1/2010 53 Male 183 lb 3/30/2010 Other Health Professional United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/1/2010 38 Female 4/6/2010 United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Hospitalization 7/1/2007 35 Female 4/19/2010 United States
Primary
Concomitant
Renal Failure Other Serious 1/1/2006 60 Female 245 lb 4/25/2010 United States
Primary
Concomitant
Tremor Hospitalization 1/1/2010 36 Female 5/21/2010 United States
Primary
Concomitant
Weight Increased Hospitalization 3/18/2010 39 Female 6/17/2010 United States
Primary
Concomitant
Platelet Count Decreased Hospitalization 3/1/2010 38 Female 6/25/2010 United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/1/2010 38 Female 7/23/2010 Consumer United States
Primary
Secondary
Concomitant
Platelet Count Decreased Hospitalization 3/1/2010 38 Female 8/3/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 55 Male 8/9/2010 United States
Primary
Concomitant
Renal Failure Hospitalization 1/1/2006 56 Female 245 lb 9/14/2010 Consumer United States
Primary
Concomitant
Rash Other Serious 1/1/2010 54 Female 9/24/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious Female 9/27/2010 Consumer United States
Primary
Secondary
Concomitant
Injection Site Discolouration Life Threatening 1/1/2010 29 Female 10/5/2010 Consumer United States
Primary
Secondary
Weight Decreased Other Serious Male 10/14/2010 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 9/29/2010 41 Male 10/19/2010 Consumer United States
Primary
Concomitant
Pyrexia Other Serious 1/1/2010 51 Female 10/22/2010 Other Health Professional United States
Primary
Concomitant
Pain Hospitalization 9/1/2010 37 Male 10/29/2010 Physician United States
Primary
Concomitant
Nephrolithiasis Hospitalization 1/1/2010 51 Male 181 lb 11/1/2010 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/2010 42 Female 11/2/2010 Pharmacist United States
Primary
Concomitant
Syncope Other Serious 1/1/2010 29 Female 11/3/2010 Consumer United States
Primary
Secondary
Concomitant
Syncope Other Serious 1/1/2010 29 Female 11/10/2010 Consumer United States
Primary
Secondary
Concomitant
Myalgia Hospitalization 1/1/2010 45 Female 236 lb 11/12/2010 Consumer United States
Primary
Concomitant
Injection Site Erythema Hospitalization 4/1/2010 41 Female 11/12/2010 Physician United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2010 38 Female 11/17/2010 Consumer United States
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Other Serious 1/1/2010 46 Female 123 lb 11/19/2010 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 59 Female 11/23/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2010 38 Female 12/21/2010 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 3/1/2010 38 Female 12/22/2010 Consumer United States
Primary
Secondary
Concomitant
Vaccination Complication Hospitalization 1/1/2010 32 Male 12/23/2010 Consumer United States
Primary
Concomitant
Leukoencephalopathy Other Serious 11/1/2009 44 Male 12/23/2010 Other Health Professional United States
Primary
Concomitant
Vein Disorder Hospitalization 1/1/2010 45 Female 236 lb 12/23/2010 Consumer United States
Primary
Concomitant
Paraesthesia Hospitalization 3/1/2010 38 Female 1/3/2011 Consumer United States
Primary
Secondary
Concomitant
Multiple Sclerosis Relapse Other Serious 1/1/2006 56 Female 245 lb 1/6/2011 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 9/12/2010 49 Female 2/1/2011 Consumer United States
Primary
Concomitant
Multiple Sclerosis Relapse Hospitalization 11/1/2010 33 Male 245 lb 2/18/2011 Consumer United States
Primary
Concomitant
Fatigue Hospitalization 1/1/2010 32 Male 2/22/2011 Consumer United States
Primary
Concomitant
Injection Site Reaction Hospitalization 9/1/2009 30 Male 209 lb 2/23/2011 Physician United States
Primary
Concomitant
Nephrolithiasis Hospitalization 9/1/2010 51 Male 161 lb 3/10/2011 Physician United States
Primary
Concomitant
Lung Neoplasm Malignant Hospitalization 1/1/2010 53 Male 183 lb 3/16/2011 Other Health Professional United States
Primary
Concomitant
Migraine Other Serious 1/1/2010 39 Female 6/16/2011 Consumer United States
Primary
Concomitant
Convulsion Other Serious 49 Female 6/29/2011 United States
Primary
Concomitant
Injection Site Erythema Other Serious 1/1/2010 50 Female 6/1/2011 United States
Primary
Concomitant
Dehydration Hospitalization 7/1/2010 45 Female 6/1/2011 Consumer United States
Primary
Concomitant
Tension Headache Hospitalization 45 Female 6/1/2011 United States
Primary
Concomitant
Injection Site Haematoma Other Serious Female 9/13/2011 Consumer United States
Primary
Secondary
Concomitant
Grand Mal Convulsion Other Serious Female 9/19/2011 Physician United States
Primary
Concomitant
Anal Haemorrhage Other Serious 9/1/2011 36 Female 9/26/2011 Consumer Brazil
Primary
Concomitant
Diabetes Mellitus Other Serious 1/1/2009 38 Female 10/20/2011 Consumer Brazil
Primary
Concomitant
Multiple Sclerosis Relapse Other Serious 1/1/2010 51 Female 10/27/2011 Other Health Professional United States
Primary
Concomitant
Cellulitis Hospitalization 8/1/2011 38 Female 10/28/2011 Consumer United States
Primary
Concomitant
Pain Hospitalization 11/1/2011 30 Male 11/11/2011 Consumer United States
Primary
Secondary
Concomitant
Head Injury Life Threatening 4/1/2011 55 Male 134 lb 11/18/2011 Consumer United States
Primary
Concomitant
Red Blood Cell Count Decreased Other Serious 59 Female 11/29/2011 Consumer United States
Primary
Secondary
Concomitant
Post Procedural Complication Hospitalization 1/1/2008 49 Female 110 lb 1/30/2012 Physician United States
Primary
Concomitant
Pyrexia 1/1/2010 51 Female 1/30/2012 Other Health Professional United States
Primary
Concomitant
Influenza Like Illness Other Serious Female 1/31/2012 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 1/19/2012 40 Female 2/2/2012 Consumer United States
Primary
Concomitant
Dehydration Other Serious Female 174 lb 2/14/2012 Physician United States
Primary
Concomitant
Skin Ulcer Hospitalization 8/1/2011 38 Female 119 lb 2/22/2012 Consumer United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 12/14/2011 48 Female 3/6/2012 Consumer Brazil
Primary
Concomitant
Fatigue Hospitalization 8/1/2011 38 Female 119 lb 3/8/2012 Physician United States
Primary
Concomitant
Pyrexia Hospitalization 29 Male 3/14/2012 United States
Primary
Secondary
Concomitant
Injection Site Reaction Other Serious 1/1/2010 39 Male 3/19/2012 Consumer United States
Primary
Secondary
Multiple Sclerosis Relapse Hospitalization 3/1/2009 50 Female 3/28/2012 Consumer United States
Primary
Concomitant
Pneumonia Hospitalization 2/1/2012 30 Male 300 lb 4/20/2012 Physician United States
Primary
Secondary
Concomitant
Hypotension Hospitalization 2/1/2012 30 Male 300 lb 4/30/2012 Physician United States
Primary
Secondary
Concomitant
Lyme Disease Hospitalization 1/1/1995 29 Male 6/27/2012 Consumer United States
Primary
Secondary
Concomitant
Emotional Distress Hospitalization 10/1/2011 58 Female 150 lb 6/29/2012 Other Health Professional United States
Primary
Concomitant
Influenza Like Illness Other Serious 1/1/2008 49 Female 110 lb 7/6/2012 Physician United States
Primary
Concomitant
Injection Site Pain Other Serious Female 163 lb 7/10/2012 Physician United States
Primary
Concomitant
Malaise Other Serious 4/13/2012 58 Female 7/13/2012 Consumer Brazil
Primary
Concomitant
Pyrexia Other Serious 2/1/2012 30 Male 300 lb 7/25/2012 Physician United States
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2012 58 Female 7/26/2012 Consumer Brazil
Primary
Concomitant
Paraesthesia Hospitalization Female 8/24/2012 Consumer Brazil
Primary
Concomitant
Pain Other Serious 8/9/2012 42 Female 8/24/2012 Consumer United States
Primary
Secondary
Concomitant

Drug Data