Depakote combined with Propranolol

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Dependence Other Serious 30 Male 1/25/2006 Consumer United States
Primary
Concomitant
Trismus Other Serious 1/5/2006 Male 176 lb 2/2/2006 Pharmacist United States
Primary
Concomitant
Thrombosis Hospitalization 12/1/2005 Male 87 lb 3/3/2006 Consumer United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 4/22/2005 26 Male 257 lb 6/27/2005 Physician United States
Primary
Concomitant
Throat Tightness Other Serious 4/7/2006 31 Male 240 lb 4/21/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Hospitalization 4/13/2004 11 Female 139 lb 11/17/2006 Physician United States
Primary
Concomitant
Psychotic Disorder Hospitalization 4/13/2004 11 Male 139 lb 12/6/2006 Physician United States
Primary
Concomitant
Tremor Other Serious 31 Male 12/22/2006 United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/2000 Male 1/12/2007 Lawyer United States
Primary
Secondary
Concomitant
Urticaria 2/8/2006 50 Male 2/28/2007 Consumer United States
Primary
Concomitant
Nail Disorder Other Serious 78 Female 114 lb 4/16/2004 United States
Primary
Concomitant
Hypomania 41 Female 3/13/2007 Physician United States
Primary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Medication Error Hospitalization 3/29/2007 Male 7/6/2007 United States
Primary
Secondary
Concomitant
Somnolence Other Serious 1/1/2007 Female 138 lb 7/23/2007 Consumer United States
Primary
Concomitant
Somnolence Other Serious 57 Female 132 lb 8/3/2007 Consumer Brazil
Primary
Concomitant
Therapeutic Response Decreased 7/1/2007 Female 8/29/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Alopecia 46 Female 182 lb 9/18/2007 United States
Primary
Concomitant
Syncope Other Serious 6/12/2007 40 Male 9/6/2007 United Kingdom
Primary
Secondary
Therapeutic Response Decreased 7/1/2007 Female 10/8/2007 Consumer United States
Primary
Concomitant
Therapy Regimen Changed 12/2/2005 32 Female 348 lb 12/2/2005 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 8/8/2007 22 Female 1/16/2008 Consumer United States
Primary
Secondary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Convulsion Other Serious 8/1/2007 Male 164 lb 1/29/2008 Physician United States
Primary
Concomitant
Speech Disorder Other Serious 12/7/2007 Female 189 lb 2/1/2008 United States
Primary
Concomitant
Off Label Use 2/25/2008 29 Male 3/5/2008 Pharmacist United States
Primary
Concomitant
Intentional Drug Misuse 2/25/2008 29 Male 3/20/2008 Pharmacist United States
Primary
Concomitant
Vomiting 1/1/1997 Female 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Intentional Overdose Other Serious 2/25/2008 29 Male 4/30/2008 Pharmacist United States
Primary
Concomitant
Somnolence Other Serious 57 Female 132 lb 6/23/2008 Physician Brazil
Primary
Concomitant
Liver Function Test Abnormal Other Serious 9/29/2008 63 Female 11/3/2008 Other Health Professional France
Primary
Concomitant
Weight Increased Other Serious Female 150 lb 1/23/2009 Consumer United States
Primary
Secondary
Concomitant
Interacting
Mixed Liver Injury Other Serious 9/29/2008 63 Female 2/13/2009 Other Health Professional France
Primary
Concomitant
Hysterectomy Other Serious 1/1/2009 Female 139 lb 2/20/2009 Consumer United States
Primary
Concomitant
Headache Female 2/27/2009 Consumer United States
Primary
Concomitant
Product Quality Issue 6/1/2008 Female 2/27/2009 Consumer United States
Primary
Concomitant
Vomiting 3/12/2009 Physician United States
Primary
Interacting
Nervousness Other Serious 6/1/2008 Female 162 lb 3/30/2009 Consumer United States
Primary
Concomitant
Tooth Abscess Other Serious 11/19/2001 42 Male 210 lb 4/13/2009 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 5/1/2000 43 Female 239 lb 4/17/2009 United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2009 60 Male 4/28/2009 Physician United States
Primary
Concomitant
Wound Hospitalization 2/10/2002 40 Male 194 lb 5/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious Female 150 lb 6/16/2009 Consumer United States
Primary
Secondary
Concomitant
Interacting
Vision Blurred Other Serious 6/20/2000 42 Male 285 lb 8/13/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/27/2003 38 Male 251 lb 8/25/2009 United States
Primary
Secondary
Concomitant
Pancreatitis Chronic Other Serious 1/1/2005 46 Male 8/26/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 8/7/2002 47 Male 224 lb 8/27/2009 United States
Primary
Concomitant
Colitis Ischaemic Hospitalization 8/20/2009 56 Female 9/4/2009 Physician United States
Primary
Concomitant
Obesity 1/1/2001 35 Female 195 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2005 45 Male 270 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased Hospitalization 9/1/2008 39 Male 175 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/6/2005 45 Male 256 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 1/1/2000 32 Male 231 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 1/1/2000 44 Female 250 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 4/1/2004 51 Male 252 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 11/7/2002 17 Female 201 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 1/1/2004 44 Male 9/23/2009 United States
Primary
Concomitant
Vision Blurred 35 Female 91 lb 9/24/2009 Physician United States
Primary
Concomitant
Peripheral Sensory Neuropathy Other Serious 10/20/2004 37 Female 215 lb 10/8/2009 United States
Primary
Concomitant
Pharyngeal Oedema Other Serious 1/1/2009 Female 10/22/2009 Other Health Professional United States
Primary
Concomitant
Pruritus Generalised Other Serious 1/1/2009 Female 179 lb 11/23/2009 Other Health Professional United States
Primary
Concomitant
Weight Decreased Hospitalization 2/4/2005 49 Male 126 lb 12/3/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2005 49 Male 245 lb 12/14/2009 United States
Primary
Secondary
Concomitant
Tremor 42 Male 315 lb 12/9/2009 Consumer United States
Primary
Concomitant
Cerebrovascular Accident Hospitalization 1/24/2009 Female 12/30/2009 Other Health Professional France
Primary
Secondary
Concomitant
Urinary Retention Hospitalization 1/24/2009 50 Female 1/6/2010 Consumer France
Primary
Secondary
Concomitant
Drug Interaction Hospitalization 1/24/2009 Female 1/26/2010 Other Health Professional France
Primary
Concomitant
Interacting
Therapeutic Agent Toxicity Hospitalization 11/23/2009 67 Male 144 lb 1/4/2010 Pharmacist United States
Primary
Secondary
Concomitant
Neck Pain Other Serious 1/2/2010 47 Female 125 lb 1/29/2010 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2005 Female 143 lb 2/5/2010 Consumer United States
Primary
Secondary
Type 2 Diabetes Mellitus Other Serious 1/1/1998 42 Male 250 lb 2/11/2010 United States
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 1/1/2009 66 Male 4/16/2010 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/1/2004 Male 4/26/2010 United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 58 Male 4/20/2010 Consumer France
Primary
Secondary
Concomitant
Spinal Compression Fracture Hospitalization 1/1/2009 66 Male 5/17/2010 Other Health Professional United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/1998 33 Male 231 lb 5/31/2010 United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/27/2003 38 Male 215 lb 6/17/2010 United States
Primary
Secondary
Concomitant
Leukopenia Other Serious 27 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Leukopenia Other Serious 3/31/2010 41 Male 6/24/2010 Pharmacist United States
Primary
Concomitant
Drug Interaction Hospitalization 1/24/2009 50 Female 6/24/2010 Other Health Professional France
Primary
Concomitant
Interacting
Nausea 5/1/2007 60 Female 211 lb 7/13/2010 Consumer United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 2/19/2010 59 Male 227 lb 7/8/2010 Consumer France
Primary
Secondary
Concomitant
Drug Ineffective 1/1/2007 69 Male 198 lb 7/15/2010 Consumer United States
Primary
Concomitant
Hip Fracture Other Serious 6/25/2010 67 Male 160 lb 8/9/2010 Physician United States
Primary
Concomitant
Hip Fracture Other Serious 6/25/2010 67 Male 160 lb 8/10/2010 Physician United States
Primary
Concomitant
Vision Blurred Other Serious 1/1/2000 42 Male 265 lb 8/26/2010 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2003 51 Female 203 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Weight Increased Hospitalization 9/1/2008 39 Male 175 lb 9/20/2010 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 197 lb 9/20/2010 United States
Primary
Concomitant
Abnormal Behaviour Hospitalization 10/25/2010 50 Female 162 lb 10/26/2010 Consumer United States
Primary
Concomitant
Poor Quality Sleep Other Serious Female 135 lb 11/30/2010 Consumer United States
Primary
Concomitant
Tremor Hospitalization 4/11/2009 54 Male 165 lb 12/7/2010 Consumer United States
Primary
Secondary
Concomitant
Treatment Noncompliance Hospitalization 10/25/2010 50 Female 162 lb 12/8/2010 Consumer United States
Primary
Concomitant
Blood Pressure Decreased Hospitalization 7/4/2010 44 Female 1/13/2011 France
Primary
Secondary
Concomitant
Dysgeusia Other Serious 12/1/2010 43 Female 137 lb 2/7/2011 Consumer Brazil
Primary
Concomitant
Amnesia Hospitalization 12/28/2010 27 Male 170 lb 1/21/2011 Pharmacist United States
Primary
Concomitant
Polycystic Ovaries Other Serious Female 144 lb 2/11/2011 Physician United States
Primary
Secondary
Concomitant
Endometriosis Hospitalization 34 Female 2/21/2011 Consumer United States
Primary
Concomitant
Headache 1/1/2011 51 Female 3/9/2011 Consumer United States
Primary
Concomitant
Alopecia 9/1/2010 83 Female 125 lb 3/14/2011 Consumer United States
Primary
Concomitant
Insomnia Other Serious 2/11/2011 Female 2/28/2011 United States
Primary
Concomitant
Confusional State Other Serious 1/18/2011 63 Female 160 lb 3/28/2011 Physician United States
Primary
Concomitant
Death Death 4/6/2011 59 Male 243 lb 4/13/2011 Physician France
Primary
Concomitant
Hyperhidrosis Death 4/6/2011 59 Male 243 lb 4/15/2011 Physician France
Primary
Concomitant
Skin Plaque Other Serious Female 183 lb 4/28/2011 Consumer United States
Primary
Secondary
Concomitant
Adrenal Insufficiency Disability 11/1/2009 20 Female 130 lb 5/10/2011 Physician United States
Primary
Concomitant
Hypertension Other Serious 6/20/2010 69 Female 5/16/2011 Physician United States
Primary
Secondary
Concomitant
Hypertension Other Serious 6/20/2010 69 Female 5/16/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Mental Disorder Hospitalization 9/10/2008 27 Female 205 lb 5/25/2011 Lawyer United States
Primary
Concomitant
Diabetic Neuropathy Other Serious 1/1/2008 38 Female 222 lb 6/1/2011 Consumer United States
Primary
Concomitant
Dyskinesia Hospitalization 4/1/2011 89 Female 6/8/2011 Other Health Professional France
Primary
Secondary
Concomitant
Dyskinesia Disability 4/1/2011 89 Female 6/15/2011 Other Health Professional France
Primary
Secondary
Concomitant
Headache Other Serious 12/1/2009 24 Female 134 lb 6/23/2011 Consumer United States
Primary
Concomitant
Interacting
Ear Discomfort Other Serious 1/1/2004 53 Female 7/20/2011 Consumer Brazil
Primary
Concomitant
Cerebrovascular Accident Other Serious 9/2/2008 41 Female 338 lb 7/26/2011 Physician United States
Primary
Concomitant
Convulsion Death 9/2/2008 41 Female 338 lb 7/26/2011 Lawyer United States
Primary
Concomitant
Musculoskeletal Stiffness Other Serious 1/1/2007 58 Female 183 lb 8/12/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Haemorrhage Other Serious 6/21/2011 61 Female 8/16/2011 Consumer United States
Primary
Concomitant
Abdominal Pain Hospitalization 11/1/2009 20 Female 123 lb 8/16/2011 Other Health Professional United States
Primary
Concomitant
Diplopia Other Serious 1/1/2000 43 Female 165 lb 9/15/2011 Consumer United States
Primary
Concomitant
Interacting
Hepatic Enzyme Increased Other Serious 1/1/2000 43 Female 165 lb 9/16/2011 Consumer United States
Primary
Concomitant
Interacting
Pain Death 8/1/2005 42 Female 257 lb 9/22/2011 Lawyer United States
Primary
Concomitant
Hypertension 1/1/2000 44 Female 250 lb 9/22/2011 United States
Primary
Concomitant
Dermal Cyst 1/1/2001 35 Female 195 lb 9/22/2011 Other Health Professional United States
Primary
Concomitant
Eye Pain Other Serious 1/1/2007 50 Male 155 lb 9/23/2011 Physician United States
Primary
Concomitant
Abdominal Pain Upper Hospitalization 11/1/2009 20 Female 123 lb 10/10/2011 Consumer United States
Primary
Concomitant
Skin Lesion Other Serious Female 183 lb 11/22/2011 Other Health Professional United States
Primary
Secondary
Concomitant
Depression Other Serious 1/24/2009 50 Female 11/28/2011 Other Health Professional France
Primary
Concomitant
Interacting
Gastric Ulcer Haemorrhage Hospitalization 11/22/2011 68 200 lb 11/29/2011 Physician United States
Primary
Secondary
Concomitant
Gait Disturbance 59 Female 12/16/2011 Physician United States
Primary
Concomitant
Abdominal Pain Hospitalization 11/1/2009 20 Female 123 lb 12/20/2011 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Death 11/22/2011 68 Male 200 lb 12/28/2011 Physician United States
Primary
Concomitant
Rash Other Serious 1/1/2009 51 Male 235 lb 1/17/2012 Consumer United States
Primary
Concomitant
Gastrointestinal Haemorrhage Hospitalization 11/22/2011 68 Male 200 lb 1/23/2012 Physician United States
Primary
Concomitant
Malaise Hospitalization 1/1/2011 51 Female 134 lb 1/23/2012 Consumer United States
Primary
Secondary
Concomitant
Alopecia 48 Female 1/28/2012 Consumer United States
Primary
Concomitant
Heart Rate Decreased Other Serious 9/9/2011 51 Female 134 lb 2/8/2012 Consumer United States
Primary
Secondary
Concomitant
Cerebral Vasoconstriction Hospitalization 1/24/2009 50 Female 154 lb 3/13/2012 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Decreased Hospitalization 9/7/2004 49 Male 130 lb 3/23/2012 Consumer United States
Primary
Concomitant
Tremor Other Serious Male 185 lb 3/26/2012 Lawyer United States
Primary
Concomitant
Drug Interaction Disability 1/24/2009 50 Female 4/10/2012 Other Health Professional France
Primary
Concomitant
Interacting
Pain In Extremity 11/19/2009 43 Female 4/17/2012 United States
Primary
Concomitant
Localised Oedema 52 Female 5/22/2012 Physician United States
Primary
Concomitant
Pain Hospitalization 11/18/2010 28 Female 135 lb 6/18/2012 Consumer United States
Primary
Concomitant
Abdominal Pain Other Serious 6/22/2010 31 Female 220 lb 6/25/2012 Lawyer United States
Primary
Secondary
Concomitant
Death Death 7/21/2011 36 Male 6/28/2012 Pharmacist United States
Primary
Concomitant
Anaemia Other Serious 11/24/2010 44 Male 172 lb 6/29/2012 Other Health Professional United Kingdom
Primary
Concomitant

Drug Data