Depakote combined with Olanzapine

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Vomiting Hospitalization 11/7/2005 34 Male 1/16/2006 France
Primary
Secondary
Gastrointestinal Haemorrhage Other Serious 11/11/2003 46 Male 172 lb 1/6/2006 Lawyer United States
Primary
Concomitant
Dyskinesia Disability 1/1/2005 Male 1/18/2006 France
Primary
Concomitant
Hypothyroidism Other Serious 12/1/2005 56 Female 154 lb 1/30/2006 United Kingdom
Primary
Concomitant
White Blood Cell Count Increased Other Serious 9/3/2003 46 Male 172 lb 2/2/2006 Lawyer United States
Primary
Secondary
Concomitant
Vomiting Hospitalization 11/7/2005 34 Male 2/15/2006 Consumer France
Primary
Secondary
Neuroleptic Malignant Syndrome Life Threatening 1/6/2006 23 Male 2/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Prothrombin Time Shortened Hospitalization 12/30/2005 43 Male 3/6/2006 Other Health Professional France
Primary
Secondary
Concomitant
Speech Disorder Other Serious 50 Female 3/17/2006 Other Health Professional France
Primary
Secondary
White Blood Cell Count Increased Other Serious 8/1/1998 46 Male 172 lb 3/7/2006 Lawyer United States
Primary
Secondary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Pseudomonas Infection Life Threatening 8/8/2005 45 Male 4/6/2006 Other Health Professional France
Primary
Secondary
Prothrombin Time Ratio Decreased Hospitalization 2/20/2006 40 Female 4/20/2006 Other Health Professional France
Primary
Secondary
Concomitant
Pleural Effusion Other Serious 40 Male 5/26/2006 Physician France
Primary
Concomitant
Platelet Count Decreased Required Intervention 9/1/2005 15 Male 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Death Death 11/25/2005 36 Male 244 lb 11/30/2005 Physician United States
Primary
Concomitant
Renal Failure Chronic Hospitalization 5/2/2006 68 Male 152 lb 6/1/2006 Pharmacist United States
Primary
Secondary
Concomitant
International Normalised Ratio Increased Hospitalization 6/1/2006 78 Male 6/14/2006 Physician United States
Primary
Concomitant
Staphylococcal Infection Life Threatening 2/20/2005 49 Male 6/16/2006 Other Health Professional France
Primary
Secondary
Concomitant
Tearfulness Hospitalization 3/8/2006 Female 6/30/2006 Other Health Professional France
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 6/11/2006 36 Male 7/14/2006 Consumer United States
Primary
Secondary
Photodermatosis Hospitalization 5/14/2006 20 Female 7/17/2006 Other Health Professional France
Primary
Secondary
Granulocytopenia Required Intervention 12/6/2005 50 Male 201 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 6/11/2006 Male 229 lb 7/28/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2006 73 Female 7/28/2006 Physician France
Primary
Secondary
Concomitant
Weight Increased 6/13/2006 Female 185 lb 8/16/2006 Physician France
Primary
Secondary
Concomitant
Weight Increased 6/13/2006 Female 185 lb 8/16/2006 Physician France
Primary
Secondary
Concomitant
Weight Increased Other Serious 1/1/2002 Female 280 lb 8/14/2006 Lawyer United States
Primary
Concomitant
International Normalised Ratio Increased Hospitalization 5/30/2006 81 Male 180 lb 9/15/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 8/1/2006 46 Male 9/15/2006 Physician Brazil
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/20/2001 37 Male 246 lb 10/15/2006 Lawyer United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/6/2006 48 Male 12/14/2006 Physician United Kingdom
Primary
Concomitant
Pyelonephritis Hospitalization 8/1/2006 63 Female 12/15/2006 Physician France
Primary
Concomitant
Interacting
Treatment Noncompliance Hospitalization 1/1/2002 Female 12/21/2006 Consumer United States
Primary
Secondary
Concomitant
Interacting
Pyelonephritis Hospitalization 8/1/2006 63 Female 12/22/2006 Physician France
Primary
Concomitant
Interacting
Prescribed Overdose Other Serious 5/9/2002 24 Male 150 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Other Serious 48 Female 10/10/2006 Consumer United States
Primary
Concomitant
Somnolence 1/18/2007 62 Female 1/30/2007 Physician United States
Primary
Concomitant
Mental Disorder Other Serious 4/4/2004 51 Female 198 lb 3/7/2007 Physician United States
Primary
Concomitant
Tardive Dyskinesia Required Intervention 40 Female 8/21/2004 Physician United States
Primary
Concomitant
Visual Field Defect Other Serious 63 Male 3/20/2007 Other Health Professional France
Primary
Concomitant
Pancreatitis Hospitalization 1/1/2004 51 Female 184 lb 4/27/2007 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2002 Male 187 lb 5/7/2007 Physician United States
Primary
Concomitant
Pulmonary Embolism Hospitalization 3/21/2007 53 Male 5/25/2007 Other Health Professional France
Primary
Secondary
Weight Increased Other Serious 1/1/2000 29 Male 4/2/2007 Consumer United States
Primary
Concomitant
Ketoacidosis Hospitalization 5/3/2007 51 Male 6/19/2007 Other Health Professional France
Primary
Secondary
Concomitant
Tardive Dyskinesia Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Tongue Paralysis Disability 8/1/2006 58 Male 6/20/2007 United Kingdom
Primary
Concomitant
Drug Ineffective Hospitalization 7/24/2007 Male 9/6/2007 Other Health Professional France
Primary
Secondary
Concomitant
Pancreatitis Other Serious 1/1/2006 Male 127 lb 9/18/2007 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 11/18/2006 Male 9/21/2007 Other Health Professional France
Primary
Concomitant
Overdose Other Serious Female 195 lb 11/21/2007 Consumer United States
Primary
Secondary
Concomitant
Thrombocytopenia Other Serious 1/9/2007 Female 12/17/2007 Physician France
Primary
Secondary
Concomitant
Nausea Hospitalization 1/1/2002 Female 287 lb 12/20/2007 Consumer United States
Primary
Concomitant
Weight Increased 5/8/2007 21 Male 163 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Mental Disorder Other Serious 1/1/2003 48 Female 198 lb 1/4/2008 Physician United States
Primary
Concomitant
Drug Level Increased Hospitalization 50 Male 2/1/2008 Physician United States
Primary
Secondary
Concomitant
Neutropenia 6/21/2007 48 Female 2/18/2008 Physician France
Primary
Concomitant
Thrombocytopenia 50 Male 2/21/2008 Physician France
Primary
Concomitant
Neutropenia Hospitalization 1/8/2008 Female 117 lb 2/25/2008 Pharmacist United States
Primary
Concomitant
Suicide Attempt Hospitalization 2/1/2007 Female 2/29/2008 Other Health Professional France
Primary
Secondary
Concomitant
Macrosomia Congenital Anomaly Male 2/29/2008 Other Health Professional France
Primary
Secondary
Pseudodementia Hospitalization 4/4/2007 Male 3/3/2008 Other Health Professional Denmark
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/30/2007 Male 3/13/2008 Consumer United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 12/31/2007 Female 3/13/2008 Other Health Professional France
Primary
Secondary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/19/2008 United Kingdom
Primary
Concomitant
Sinus Bradycardia Other Serious 42 Male 3/20/2008 Other Health Professional United Kingdom
Primary
Concomitant
Weight Increased Other Serious 12/30/2007 Male 4/4/2008 Consumer United States
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 4/10/2008 Lawyer United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 3/19/2007 Male 4/11/2008 Physician United States
Primary
Secondary
Concomitant
Vomiting 1/1/1997 Female 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Skin Burning Sensation Male 4/11/2008 Physician United States
Primary
Concomitant
Suicide Attempt Life Threatening 35 Female 4/17/2008 Physician Brazil
Primary
Secondary
Concomitant
White Blood Cell Count Decreased Disability 1/1/2005 Male 180 lb 4/30/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Decreased Disability 1/1/2005 Male 180 lb 5/2/2008 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2004 51 Female 184 lb 5/27/2008 United States
Primary
Concomitant
Drug Exposure During Pregnancy Congenital Anomaly 0 Male 5/29/2008 Physician France
Primary
Secondary
White Blood Cell Count Decreased Other Serious 1/20/2008 Male 6/23/2008 Other Health Professional United Kingdom
Primary
Concomitant
Withdrawal Syndrome Hospitalization 1/1/2007 Male 174 lb 7/3/2008 United States
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 7/22/2008 Other Health Professional United States
Primary
Concomitant
Scrotal Swelling Other Serious 11/1/2007 Male 8/15/2008 Consumer United States
Primary
Secondary
Concomitant
Swelling 1/1/2002 Female 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Thrombocytopenia Hospitalization 6/23/2008 50 Female 9/18/2008 Other Health Professional France
Primary
Secondary
Concomitant
Hospitalisation Hospitalization 27 Female 10/15/2008 Other Health Professional France
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 10/17/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 10/31/2008 12/15/2008 Physician United Kingdom
Primary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 1/26/2009 Other Health Professional United States
Primary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 1/29/2009 Other Health Professional United States
Primary
Concomitant
Neutrophil Count Decreased Other Serious 10/14/2008 Male 2/10/2009 Physician United States
Primary
Secondary
Concomitant
Overdose Hospitalization 1/1/2008 52 Female 2/17/2009 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Death 11/21/2008 88 Male 148 lb 12/5/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vision Blurred Other Serious 1/26/2009 3/2/2009 Physician United Kingdom
Primary
Concomitant
Contusion 3/12/2009 Physician United States
Primary
Concomitant
Weight Increased 50 Male 3/12/2009 Consumer United States
Primary
Interacting
Libido Decreased Male 3/12/2009 Consumer United States
Primary
Concomitant
Psychotic Disorder 17 Male 3/12/2009 Consumer
Primary
Concomitant
Interacting
Pancreatitis 3/12/2009 Physician
Primary
Concomitant
Flat Affect 9/19/2008 Male 246 lb 3/12/2009 Consumer United States
Primary
Concomitant
Treatment Noncompliance 50 Female 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Drug Toxicity Death 9/11/2004 Female 125 lb 4/17/2009 Other Health Professional United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/6/2008 Female 97 lb 4/24/2009 Physician Japan
Primary
Concomitant
Vision Blurred Other Serious 3/24/2003 45 Female 138 lb 5/18/2009 United States
Primary
Concomitant
Vomiting Required Intervention 11/1/2008 56 Male 175 lb 12/1/2008 Consumer United States
Primary
Secondary
Visual Impairment Other Serious 41 Male 6/12/2009 Physician United Kingdom
Primary
Concomitant
Renal Failure Other Serious 3/15/2009 52 Male 137 lb 7/3/2009 Physician United States
Primary
Secondary
Concomitant
Diabetic Retinopathy Other Serious 10/1/2004 41 Male 152 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 10/14/2008 Male 7/27/2009 Physician United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 4/10/2002 47 Female 198 lb 7/29/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 3/1/2000 41 Female 206 lb 7/27/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/1999 26 Female 169 lb 8/3/2009 United States
Primary
Concomitant
Visual Impairment 6/1/2009 41 Male 243 lb 8/3/2009 Physician United Kingdom
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 7/8/2003 49 Female 218 lb 8/12/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2005 43 Male 219 lb 8/12/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2002 50 Male 190 lb 8/14/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 8/7/2002 47 Male 224 lb 8/27/2009 United States
Primary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2003 35 Female 134 lb 8/28/2009 United States
Primary
Secondary
Concomitant
Diabetic Complication Other Serious 1/1/2004 51 Male 207 lb 9/3/2009 United States
Primary
Concomitant
Pallor Hospitalization 5/21/2009 58 Male 9/10/2009 Physician United Kingdom
Primary
Concomitant
Pulmonary Oedema Other Serious 10/1/2008 Male 9/11/2009 Other Health Professional France
Primary
Concomitant
Pulmonary Oedema Other Serious 10/1/2008 Male 9/14/2009 Other Health Professional France
Primary
Concomitant
Pallor Hospitalization 5/21/2009 58 Male 9/9/2009 Other Health Professional United Kingdom
Primary
Concomitant
Glycosuria Hospitalization 3/7/2006 31 Female 156 lb 9/23/2009 United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/1998 33 Male 350 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2004 27 Female 306 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious Female 425 lb 9/23/2009 United States
Primary
Concomitant
Pancreatitis Other Serious 7/27/2005 18 Male 123 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus 5/1/2003 45 Female 200 lb 9/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2001 44 Male 262 lb 10/14/2009 United States
Primary
Concomitant
Vomiting Hospitalization 8/25/2009 48 Female 10/22/2009 Pharmacist United States
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/1/2003 40 Female 1/22/2010 Consumer United Kingdom
Primary
Secondary
Concomitant
Suicide Attempt Hospitalization 1/1/2003 40 Female 1/29/2010 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Paraesthesia 12/1/2008 28 Male 2/26/2010 Consumer United States
Primary
Concomitant
Blood Triglycerides Increased 6/30/2008 31 Male 269 lb 11/18/2008 Other Health Professional United States
Primary
Concomitant
White Blood Cell Count Decreased Other Serious 11/22/2006 40 Male 5/25/2010 Physician United Kingdom
Primary
Concomitant
Suicide Attempt Other Serious 4/10/2002 47 Female 198 lb 6/11/2010 United States
Primary
Concomitant
Weight Decreased Other Serious Male 6/14/2010 Consumer United States
Primary
Secondary
Concomitant
Erectile Dysfunction Other Serious 10/1/2004 41 Male 152 lb 7/2/2010 United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious Male 7/6/2010 Consumer United States
Primary
Secondary
Concomitant
Therapeutic Agent Toxicity 2/26/2010 25 Female 3/16/2010 Other Health Professional United States
Primary
Concomitant
Mental Disorder Male 9/20/2010 Consumer United States
Primary
Concomitant
Tardive Dyskinesia Other Serious Female 197 lb 9/20/2010 United States
Primary
Concomitant
Pancreatitis Other Serious Female 222 lb 9/20/2010 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 35 Female 310 lb 9/20/2010 United States
Primary
Secondary
Concomitant
Erythema Nodosum Other Serious 5/1/2010 33 Female 9/23/2010 Other Health Professional United Kingdom
Primary
Concomitant
Hallucination, Auditory Other Serious Male 10/1/2010 Other Health Professional United Kingdom
Primary
Concomitant
Mental Disorder Other Serious 4/10/2002 47 Female 198 lb 1/21/2011 United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 67 Male 159 lb 4/14/2011 Pharmacist United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/1/2008 15 Male 6/1/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
White Blood Cell Count Increased Hospitalization 1/1/2008 16 Male 6/30/2011 Other Health Professional United Kingdom
Primary
Secondary
Concomitant

Drug Data