Depakote combined with Metformin Hcl

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Ventricular Fibrillation Other Serious 1/11/2006 27 Female 2/10/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 1/1/2000 41 Female 155 lb 3/2/2006 Lawyer United States
Primary
Concomitant
Hypoaesthesia Other Serious 4/17/2006 51 Female 220 lb 7/19/2006 United States
Primary
Concomitant
Tremor 2/9/2006 63 Male 9/6/2006 Consumer United States
Primary
Concomitant
Sleep Disorder Other Serious 8/1/2006 Female 9/8/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 12/15/2006 Pharmacist France
Primary
Concomitant
Grand Mal Convulsion Other Serious 10/2/2006 46 Female 12/14/2006 United States
Primary
Secondary
Concomitant
Pulmonary Embolism Hospitalization Female 255 lb 12/28/2006 Consumer United States
Primary
Concomitant
Akathisia 3/30/2006 51 Male 12/29/2006 Other Health Professional United States
Primary
Concomitant
Presyncope 5/10/2006 61 Female 143 lb 12/29/2006 Consumer United States
Primary
Concomitant
Pancreatitis Other Serious 1/1/2002 Female 121 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Weight Increased Hospitalization 44 Female 2/13/2007 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 3/20/2007 Pharmacist France
Primary
Concomitant
Lymphadenopathy Hospitalization 3/12/2005 61 Male 193 lb 8/25/2005 Physician United States
Primary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 4/4/2007 Pharmacist France
Primary
Secondary
Concomitant
Weight Increased Other Serious 10/20/2006 Male 231 lb 4/19/2007 Pharmacist France
Primary
Secondary
Concomitant
Weight Increased Other Serious Female 3/28/2007 United States
Primary
Secondary
Concomitant
Priapism Other Serious 1/1/2006 34 Male 137 lb 3/28/2007 Physician United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 5/25/2007 Male 182 lb 6/5/2007 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 6/1/2007 Consumer United States
Primary
Concomitant
Urinary Retention Hospitalization 2/20/2006 61 Female 224 lb 6/5/2007 Physician United States
Primary
Concomitant
Mania Hospitalization 6/14/2007 59 Male 6/21/2007 Other Health Professional United States
Primary
Concomitant
Transient Ischaemic Attack Other Serious 1/1/2004 75 Female 6/30/2007 Physician United States
Primary
Concomitant
Mania Hospitalization 6/14/2007 Male 7/6/2007 United States
Primary
Concomitant
Vomiting Other Serious 1/1/2007 Female 143 lb 7/11/2007 Consumer United States
Primary
Secondary
Concomitant
Psychotic Disorder Other Serious 5/25/2007 Male 182 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Psychotic Disorder Other Serious 5/25/2007 Male 182 lb 7/24/2007 Other Health Professional United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 7/25/2007 Consumer United States
Primary
Secondary
Concomitant
Mood Swings 8/1/2006 67 Female 180 lb 7/11/2007 Other Health Professional United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Weight Increased 1/1/2004 64 Male 255 lb 9/17/2007 Pharmacist United States
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Middle Insomnia 1/1/2005 9/24/2007 Consumer United States
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Death Disability 1/7/2007 50 Male 10/8/2007 Consumer United States
Primary
Concomitant
Refusal Of Treatment By Patient Other Serious 9/11/2006 48 Female 162 lb 11/20/2007 Consumer United States
Primary
Concomitant
Vomiting 4/22/2007 69 Female 10/8/2007 Consumer United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Stupor Hospitalization 12/1/2007 Female 2/15/2008 Physician United States
Primary
Concomitant
Ventricular Fibrillation Other Serious 1/11/2006 Female 3/31/2008 Physician United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/11/2006 Female 140 lb 4/2/2008 Physician United States
Primary
Concomitant
Tremor 7/1/2007 Female 243 lb 4/11/2008 Consumer United States
Primary
Concomitant
Unresponsive To Stimuli Hospitalization 4/1/2008 68 Female 4/25/2008 Physician United States
Primary
Secondary
Concomitant
Depression Other Serious 4/1/2008 Female 180 lb 5/8/2008 United States
Primary
Concomitant
Death Death 4/15/2008 Male 5/12/2008 Pharmacist United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2000 Male 220 lb 6/4/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 1/11/2006 Female 140 lb 6/1/2008 Physician United States
Primary
Concomitant
Nausea 12/1/2007 53 Male 4/10/2008 Consumer United States
Primary
Concomitant
Renal Failure Hospitalization 5/1/2008 47 Male 265 lb 6/26/2008 Consumer United States
Primary
Concomitant
Somnolence Other Serious 12/1/2006 Male 225 lb 6/27/2008 Consumer United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/10/2008 Female 280 lb 7/25/2008 Consumer United States
Primary
Concomitant
Unevaluable Event Hospitalization 1/1/2007 Male 230 lb 7/29/2008 Consumer United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2004 Female 205 lb 7/31/2008 Consumer United States
Primary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/1/2008 Male 210 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Unevaluable Event Other Serious 7/1/2008 Male 210 lb 8/8/2008 Consumer United States
Primary
Secondary
Concomitant
Toxic Epidermal Necrolysis Death Male 8/15/2008 Lawyer United States
Primary
Concomitant
Swelling 1/1/2002 Female 9/2/2008 Physician United States
Primary
Secondary
Concomitant
Dehydration Hospitalization 7/28/2008 Male 9/3/2008 United States
Primary
Secondary
Concomitant
Sepsis Hospitalization 8/28/2008 Female 270 lb 9/12/2008 Other Health Professional United States
Primary
Concomitant
Dehydration Hospitalization 7/26/2008 Male 9/12/2008 United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Middle Insomnia 11/1/2006 9/10/2008 Consumer United States
Primary
Secondary
Concomitant
Weight Decreased Other Serious 1/1/2007 Female 250 lb 9/19/2008 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus 2/20/2006 49 Female 314 lb 9/23/2008 Other Health Professional United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 60 Male 9/25/2008 United States
Primary
Concomitant
Vomiting Other Serious 10/11/2006 Male 254 lb 9/26/2008 Consumer United States
Primary
Concomitant
Convulsion Hospitalization 7/26/2008 Male 10/1/2008 United States
Primary
Secondary
Concomitant
Vomiting Other Serious 10/11/2006 Male 254 lb 10/3/2008 Consumer United States
Primary
Secondary
Concomitant
Aspartate Aminotransferase Increased Other Serious 8/5/2008 22 Female 221 lb 11/4/2008 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 1/1/2008 56 Female 176 lb 11/7/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Nausea 1/1/2008 68 Female 9/2/2008 Consumer United States
Primary
Concomitant
Lethargy Hospitalization 6/12/2008 65 Female 152 lb 6/13/2008 United States
Primary
Concomitant
Platelet Count Decreased Other Serious 11/18/2008 Male 500 lb 11/28/2008 Physician United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2008 Male 500 lb 12/15/2008 Physician United States
Primary
Concomitant
Sepsis Hospitalization 8/28/2008 Female 270 lb 12/31/2008 Other Health Professional United States
Primary
Concomitant
Diabetes Mellitus Death 1/1/1990 51 Male 204 lb 1/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Vomiting Other Serious 1/1/2008 56 Female 176 lb 2/6/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Hospice Care Other Serious 65 Male 2/3/2009 Physician United States
Primary
Concomitant
Platelet Count Decreased Other Serious 1/1/2008 Male 500 lb 2/5/2009 Physician United States
Primary
Concomitant
Renal Failure Other Serious 2/19/2009 Physician United States
Primary
Secondary
Weight Increased 35 Male 3/12/2009 Consumer United States
Primary
Secondary
Concomitant
Chest Pain Other Serious 1/1/2008 56 Female 176 lb 3/12/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Level Decreased 1/1/2006 Male 200 lb 3/12/2009 Physician United States
Primary
Secondary
Concomitant
Type 2 Diabetes Mellitus Other Serious 11/5/2002 47 Male 195 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Sleep Apnoea Syndrome Other Serious 4/27/2005 51 Male 178 lb 4/3/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 8/1/2005 42 Female 257 lb 4/3/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Death 10/7/2002 40 Female 349 lb 4/3/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 10/1/1997 42 Male 236 lb 4/3/2009 United States
Primary
Concomitant
Pancreatitis Hospitalization Male 4/1/2009 Physician United States
Primary
Concomitant
Withdrawal Syndrome Other Serious 10/17/2008 Female 111 lb 4/8/2009 Consumer United States
Primary
Concomitant
Suicidal Ideation Other Serious 11/17/1998 51 Female 172 lb 4/10/2009 United States
Primary
Concomitant
Vomiting Hospitalization 5/19/1999 47 Female 160 lb 4/14/2009 United States
Primary
Concomitant
Suicidal Ideation Other Serious 7/1/2004 42 Female 190 lb 4/14/2009 United States
Primary
Concomitant
Organic Erectile Dysfunction Other Serious 1/2/2002 46 Male 240 lb 4/14/2009 United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death Male 4/24/2009 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 2/1/2009 60 Male 4/28/2009 Physician United States
Primary
Concomitant
Toxic Epidermal Necrolysis Death Male 5/5/2009 Lawyer United States
Primary
Concomitant
Thinking Abnormal Hospitalization 5/12/1998 39 Female 165 lb 5/19/2009 United States
Primary
Concomitant
Pulmonary Embolism Other Serious 9/1/2004 43 Male 5/19/2009 United States
Primary
Concomitant
Substance Abuse Other Serious 4/21/2001 35 Male 269 lb 5/19/2009 United States
Primary
Concomitant
Tremor Hospitalization 12/1/2003 55 Female 198 lb 5/19/2009 United States
Primary
Concomitant
Xerosis Other Serious 1/1/2000 42 Female 320 lb 5/20/2009 United States
Primary
Concomitant
Viral Upper Respiratory Tract Infection Hospitalization 4/26/2000 35 Male 230 lb 5/20/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 6/19/2003 38 Male 220 lb 5/20/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 34 Female 225 lb 5/20/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Hospitalization 3/23/2002 26 Female 246 lb 5/20/2009 United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 6/18/1998 43 Female 196 lb 5/20/2009 United States
Primary
Secondary
Concomitant
Agranulocytosis Life Threatening 1/7/2009 45 Male 2/18/2009 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Other Serious 4/20/2006 48 Female 200 lb 6/1/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 1/1/2002 55 Female 155 lb 6/1/2009 United States
Primary
Concomitant
Visual Impairment Hospitalization 12/18/2008 60 Male 6/3/2009 Physician United States
Primary
Concomitant
Renal Failure Acute Other Serious 10/17/2002 65 Female 164 lb 6/3/2009 United States
Primary
Concomitant
Weight Decreased Hospitalization 1/1/2007 Male 206 lb 6/19/2009 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 10/11/2003 26 Female 174 lb 6/23/2009 United States
Primary
Concomitant
Tooth Abscess Other Serious 5/1/2004 48 Female 179 lb 4/20/2009 Physician United States
Primary
Secondary
Concomitant
Sinusitis Other Serious 1/1/2003 29 Male 328 lb 7/9/2009 United States
Primary
Concomitant
Presyncope 6/20/2009 Female 7/9/2009 Consumer
Primary
Concomitant
Tardive Dyskinesia Other Serious 1/1/2006 28 Female 218 lb 7/13/2009 United States
Primary
Concomitant
Diabetic Retinal Oedema Other Serious 8/1/2004 42 Male 188 lb 7/14/2009 United States
Primary
Concomitant
Obesity Other Serious 11/1/2004 27 Female 230 lb 7/15/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 5/2/2000 43 Female 270 lb 7/16/2009 United States
Primary
Concomitant
Weight Increased Other Serious 11/19/1999 44 Female 256 lb 7/17/2009 United States
Primary
Concomitant
Diabetic Retinopathy Other Serious 10/1/2004 41 Male 152 lb 7/21/2009 United States
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 1/1/1993 22 144 lb 7/22/2009 United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Other Serious 1/1/2002 45 Male 279 lb 7/22/2009 United States
Primary
Concomitant
Death Death 6/10/2009 30 Female 7/16/2009 Physician United States
Primary
Concomitant
Traumatic Brain Injury Other Serious 1/1/2003 40 Male 209 lb 7/23/2009 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/15/2001 48 Female 223 lb 7/23/2009 United States
Primary
Concomitant
Trismus 8/15/2009 Female 8/21/2009 Consumer
Primary
Concomitant
Urticaria 3/29/2009 Male 8/22/2009 United States
Primary
Concomitant
Flushing 5/17/2009 Female 210 lb 8/22/2009 United States
Primary
Concomitant
Weight Increased Other Serious 10/1/2000 39 Female 242 lb 9/3/2009 United States
Primary
Concomitant
Weight Increased Other Serious 1/1/2002 38 Female 250 lb 9/15/2009 United States
Primary
Secondary
Concomitant
Injury Other Serious 62 Male 200 lb 9/8/2009 United States
Primary
Concomitant
Vocal Cord Polyp Other Serious 2/17/2004 57 Female 192 lb 9/16/2009 United States
Primary
Concomitant
Oedema 7/10/2009 Female 170 lb 9/16/2009 Physician United States
Primary
Concomitant
Urinary Incontinence Hospitalization 7/26/1999 49 Female 274 lb 9/17/2009 United States
Primary
Concomitant
Diabetic Ketoacidosis Other Serious 2/1/2005 48 Female 213 lb 9/23/2009 United States
Primary
Concomitant
Diabetic Coma Other Serious 7/1/2005 40 Male 248 lb 9/23/2009 United States
Primary
Concomitant
Diabetes Mellitus 9/1/2005 43 Female 285 lb 9/23/2009 United States
Primary
Concomitant
Vomiting Other Serious 10/3/2002 25 Female 183 lb 9/23/2009 Other Health Professional United States
Primary
Concomitant
Weight Increased 1/1/2004 64 Male 254 lb 9/23/2009 Pharmacist United States
Primary
Concomitant
Weight Increased 4/26/2001 47 Female 253 lb 9/23/2009 United States
Primary
Secondary
Concomitant
Obesity 1/1/2001 35 Female 195 lb 9/23/2009 United States
Primary
Concomitant
Weight Increased 1/1/2005 25 Female 312 lb 9/23/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Tardive Dyskinesia Other Serious 10/1/2000 40 Male 279 lb 9/23/2009 United States
Primary
Concomitant
Furuncle 10/1/2003 48 Male 206 lb 9/23/2009 United States
Primary
Concomitant

Drug Data