Depakote combined with Lorazepam

Reports:

Reaction Outcome Event Date Age Sex Weight Reported Reporter Country Treatment
Role Name
Weight Increased Other Serious 4/29/1997 44 Female 237 lb 12/30/2005 Consumer United States
Primary
Secondary
Concomitant
Dyskinesia Disability 1/1/2005 Male 1/18/2006 France
Primary
Concomitant
Rhabdomyolysis Other Serious 1/1/2002 31 Male 211 lb 2/1/2006 Lawyer United States
Primary
Concomitant
Post Procedural Complication Other Serious 4/7/2000 71 Female 150 lb 2/9/2006 United States
Primary
Concomitant
Drug Tolerance Hospitalization 16 Female 2/9/2006 Physician United States
Primary
Concomitant
Neuroleptic Malignant Syndrome Life Threatening 1/6/2006 23 Male 2/24/2006 Consumer United Kingdom
Primary
Secondary
Concomitant
Renal Disorder Other Serious 12/1/2005 37 Female 160 lb 2/14/2006 Consumer United States
Primary
Secondary
Concomitant
Drug Ineffective 12/1/2005 50 Male 2/28/2006 Consumer United States
Primary
Concomitant
Urinary Tract Disorder Hospitalization 1/1/2003 74 Male 231 lb 3/7/2006 Physician United States
Primary
Concomitant
Renal Disorder Other Serious 12/1/2005 37 Female 160 lb 2/27/2006 Consumer United States
Primary
Secondary
Concomitant
Vomiting Other Serious 12/2/2001 44 Female 201 lb 3/22/2006 Lawyer United States
Primary
Concomitant
Schizoaffective Disorder Other Serious 8/28/2002 31 Female 211 lb 3/9/2006 Lawyer United States
Primary
Concomitant
Vomiting Other Serious 8/1/2001 44 Female 201 lb 3/23/2006 Physician United States
Primary
Concomitant
Cardiomyopathy Hospitalization 3/17/2006 45 Male 192 lb 3/31/2006 Pharmacist United States
Primary
Concomitant
Renal Disorder Other Serious 12/1/2005 37 Female 160 lb 3/20/2006 Consumer United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 12/18/1998 26 Male 243 lb 4/1/2006 Lawyer United States
Primary
Concomitant
Throat Tightness Other Serious 4/7/2006 31 Male 240 lb 4/21/2006 Consumer United States
Primary
Concomitant
Thrombosis Hospitalization 8/29/2001 58 Female 130 lb 5/8/2006 Lawyer United States
Primary
Concomitant
Urinary Tract Infection Hospitalization 1/1/2004 60 Female 121 lb 5/10/2006 Physician United States
Primary
Concomitant
Vomiting Required Intervention Male 5/11/2006 Physician United States
Primary
Concomitant
Vomiting Required Intervention Male 5/22/2006 Physician United States
Primary
Concomitant
Platelet Count Decreased Required Intervention 9/1/2005 15 Male 1/31/2006 Physician United States
Primary
Secondary
Concomitant
Tremor Hospitalization 6/1/2005 43 Male 168 lb 9/19/2005 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 21 Female 130 lb 12/29/2005 Consumer United States
Primary
Secondary
Concomitant
Urinary Tract Infection Hospitalization 12/1/2005 62 Male 185 lb 6/12/2006 Consumer United States
Primary
Concomitant
Vomiting Required Intervention Male 6/7/2006 Physician United States
Primary
Concomitant
Upper Respiratory Tract Infection Other Serious 1/1/2003 60 Male 185 lb 6/15/2006 Consumer United States
Primary
Concomitant
Psychotic Disorder Other Serious Male 7/20/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 12/6/2005 50 Male 201 lb 3/7/2006 Consumer United States
Primary
Secondary
Concomitant
Granulocytopenia Required Intervention 11/1/2005 44 Male 217 lb 5/17/2006 United States
Primary
Secondary
Concomitant
Convulsion Hospitalization 7/1/2006 Male 145 lb 8/17/2006 Consumer United States
Primary
Concomitant
Grand Mal Convulsion Other Serious 5/10/2006 52 Female 155 lb 8/18/2006 Physician United States
Primary
Concomitant
Weight Decreased Other Serious 4/21/2001 24 Male 150 lb 7/14/2006 Other Health Professional United States
Primary
Concomitant
Sleep Disorder Other Serious 8/1/2006 Female 9/8/2006 United States
Primary
Secondary
Concomitant
Priapism Other Serious 9/1/2005 73 Male 144 lb 7/14/2006 Physician United States
Primary
Concomitant
Pancreatitis Hospitalization 26 Male 9/22/2006 Physician United States
Primary
Concomitant
Intervertebral Disc Protrusion Other Serious 12/1/2005 56 Male 9/20/2006 Consumer United States
Primary
Concomitant
Thrombocytopenia Other Serious 7/26/2006 42 Male 190 lb 10/2/2006 Physician United States
Primary
Secondary
Concomitant
Shock Death 9/1/2006 56 Female 140 lb 10/4/2006 Physician United States
Primary
Secondary
Concomitant
Swelling Face Other Serious 8/7/2006 48 Male 11/2/2006 Other Health Professional United Kingdom
Primary
Concomitant
Hypertension Other Serious 22 Male 11/3/2006 Pharmacist United States
Primary
Concomitant
Therapeutic Response Decreased Other Serious Male 10/31/2006 Pharmacist United States
Primary
Secondary
Concomitant
Hypertension Other Serious 22 Male 11/13/2006 Pharmacist United States
Primary
Concomitant
Neutropenia 8/10/2006 61 Female 209 lb 11/14/2006 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Pancytopenia Required Intervention 11/14/2006 60 Male 201 lb 11/22/2006 Pharmacist United States
Primary
Concomitant
Vomiting Other Serious 7/26/2001 41 Female 150 lb 12/22/2006 United States
Primary
Secondary
Concomitant
Weight Increased Other Serious 6/1/2005 Female 152 lb 1/10/2007 Physician France
Primary
Secondary
Concomitant
Suicide Attempt Other Serious 6/26/2006 Female 1/11/2007 Lawyer United States
Primary
Secondary
Concomitant
Visceral Congestion Other Serious 61 Male 1/12/2007 United States
Primary
Secondary
Concomitant
Accidental Death Death 61 Male 1/23/2007
Primary
Secondary
Concomitant
Prescribed Overdose Other Serious 45 Female 10/10/2006 Physician United States
Primary
Concomitant
Weight Increased Other Serious 48 Female 10/10/2006 Consumer United States
Primary
Concomitant
Diabetes Mellitus Non-insulin-dependent Other Serious 10/1/2000 32 Female 344 lb 10/10/2006 Lawyer United States
Primary
Concomitant
Hyperthermia Malignant Hospitalization 11/25/2006 Female 2/6/2007 Physician Italy
Primary
Concomitant
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 228 lb 2/14/2007 Physician United States
Primary
Concomitant
Pulmonary Oedema Death 61 Male 2/15/2007 Other Health Professional United States
Primary
Secondary
Concomitant
Drug Ineffective 12/1/2005 50 Male 2/28/2007 Consumer United States
Primary
Concomitant
Rash Other Serious 4/17/2006 33 Female 2/28/2007 Consumer United States
Primary
Secondary
Concomitant
Vomiting Life Threatening 2/6/2007 66 Female 3/6/2007 Physician Italy
Primary
Concomitant
Visceral Congestion Death 61 Male 3/5/2007 United States
Primary
Concomitant
Syncope Other Serious 7/12/2006 30 Female 130 lb 12/19/2006 Physician United States
Primary
Concomitant
Serotonin Syndrome Hospitalization 10/1/2006 51 Female 224 lb 4/23/2007 Physician United States
Primary
Concomitant
Tricuspid Valve Incompetence Other Serious 7/26/2001 Female 150 lb 5/15/2007 Lawyer United States
Primary
Secondary
Concomitant
Depression Hospitalization 4/7/2007 Male 237 lb 5/16/2007 Physician United States
Primary
Secondary
Concomitant
Red Blood Cell Count Decreased Other Serious 12/1/2001 49 Male 161 lb 5/18/2007 Consumer United States
Primary
Concomitant
Drug Ineffective Hospitalization 8/3/2006 52 Male 155 lb 3/28/2007 Pharmacist United States
Primary
Concomitant
Pancreatitis Hospitalization 1/29/2006 25 Male 200 lb 4/12/2007 Consumer United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 1/1/2001 35 Female 144 lb 4/12/2007 Other Health Professional United States
Primary
Concomitant
Weight Increased Other Serious 49 Female 4/2/2007 Consumer United States
Primary
Concomitant
Weight Increased Other Serious 1/1/1999 47 210 lb 4/2/2007 Lawyer United States
Primary
Concomitant
Mania Hospitalization 6/14/2007 59 Male 6/21/2007 Other Health Professional United States
Primary
Concomitant
Medication Error Hospitalization 3/29/2007 Male 7/6/2007 United States
Primary
Secondary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 7/6/2007 Physician France
Primary
Concomitant
Mania Hospitalization 6/14/2007 Male 7/6/2007 United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/26/2000 29 Female 155 lb 7/12/2007 Other Health Professional United States
Primary
Concomitant
Pain In Extremity Other Serious Male 8/20/2007 Other Health Professional France
Primary
Concomitant
Platelet Count Increased Other Serious 7/9/2007 50 Male 320 lb 8/23/2007 Physician United Kingdom
Primary
Concomitant
Intraocular Pressure Increased Female 8/30/2007 Consumer United States
Primary
Concomitant
Platelet Count Increased Other Serious 6/23/2007 50 Male 320 lb 9/13/2007 Physician United Kingdom
Primary
Concomitant
Malaise Other Serious 6/12/2007 40 Male 9/10/2007 United Kingdom
Primary
Secondary
Concomitant
Convulsion Hospitalization 1/10/2003 11 Male 9/17/2007 Other Health Professional United States
Primary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 9/18/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Malaise Other Serious 1/1/2007 40 Male 10/4/2007 Other Health Professional United Kingdom
Primary
Secondary
Concomitant
Weight Increased Other Serious 2/4/2006 Male 10/5/2007 United States
Primary
Secondary
Concomitant
Parkinsonism Death 9/16/2007 Female 150 lb 10/9/2007 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 10/16/2002 11 Male 11/2/2007 Other Health Professional United States
Primary
Concomitant
Abasia Other Serious 7/1/2007 94 Female 11/1/2007 Physician United States
Primary
Concomitant
Type 2 Diabetes Mellitus Other Serious 8/26/2000 29 Female 155 lb 11/6/2007 Other Health Professional United States
Primary
Concomitant
Pancreatitis Acute Hospitalization 6/1/2006 Male 11/12/2007 Physician France
Primary
Concomitant
Diverticulitis Hospitalization 1/1/2004 Female 195 lb 11/21/2007 Consumer United States
Primary
Concomitant
Dystonia 10/30/2006 18 Male 180 lb 10/31/2006 Pharmacist United States
Primary
Concomitant
Respiratory Arrest Other Serious 8/24/2007 43 Male 12/20/2007 Physician United States
Primary
Concomitant
Respiratory Failure Life Threatening 7/15/2007 Male 12/20/2007 Physician United States
Primary
Secondary
Concomitant
Rhabdomyolysis Required Intervention 6/7/2007 26 Male 180 lb 6/7/2007 Pharmacist United States
Primary
Concomitant
Weight Increased 5/8/2007 21 Male 163 lb 5/8/2007 Pharmacist United States
Primary
Concomitant
Tachycardia Other Serious 1/1/2002 52 Female 150 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Vision Blurred Other Serious 4/26/2000 Male 301 lb 1/25/2008 Other Health Professional United States
Primary
Concomitant
Tardive Dyskinesia Hospitalization 10/16/2002 11 Male 1/29/2008 Other Health Professional United States
Primary
Concomitant
Speech Disorder Other Serious 12/7/2007 Female 189 lb 2/1/2008 United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/12/2008 Physician United States
Primary
Concomitant
Atrial Fibrillation Hospitalization 1/30/2008 60 Female 213 lb 2/13/2008 Physician United States
Primary
Concomitant
Tremor Life Threatening 7/15/2007 Male 2/15/2008 Physician United States
Primary
Secondary
Concomitant
Renal Disorder Hospitalization 8/1/1997 61 Male 2/18/2008 Physician United States
Primary
Secondary
Concomitant
Respiratory Arrest Other Serious 8/24/2007 43 Male 2/20/2008 Physician United States
Primary
Concomitant
Suicidal Ideation Hospitalization 4/7/2007 Male 237 lb 3/19/2008 Physician United States
Primary
Secondary
Concomitant
Type 1 Diabetes Mellitus Hospitalization 1/1/2002 27 Female 299 lb 3/24/2008 Physician United States
Primary
Concomitant
Loss Of Consciousness Other Serious 1/30/2006 47 Male 217 lb 4/10/2008 Other Health Professional United States
Primary
Concomitant
Headache 11/1/2006 Male 201 lb 4/11/2008 Consumer United States
Primary
Concomitant
Urine Analysis Abnormal Hospitalization 1/1/2001 Female 144 lb 4/11/2008 Other Health Professional United States
Primary
Concomitant
Vomiting 1/1/1997 Female 4/11/2008 Consumer United States
Primary
Secondary
Concomitant
Tremor 7/1/2007 Female 243 lb 4/11/2008 Consumer United States
Primary
Concomitant
Weight Increased 12/1/2007 Female 180 lb 4/11/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Feeling Abnormal 1/1/2005 Female 115 lb 4/11/2008 Consumer United States
Primary
Concomitant
Drug Interaction 2/13/2008 18 Female 143 lb 4/11/2008 Physician United States
Primary
Concomitant
Interacting
Refusal Of Treatment By Relative Life Threatening 4/13/2008 Male 185 lb 4/14/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Vertigo Hospitalization Male 4/23/2008 Consumer France
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 78 Male 196 lb 5/9/2008 Physician United States
Primary
Secondary
Death Death 4/15/2008 Male 5/12/2008 Pharmacist United States
Primary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 70 Female 87 lb 5/27/2008 United States
Primary
Concomitant
Postictal State Other Serious 4/24/2008 Male 299 lb 5/30/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/1/2006 78 Male 196 lb 5/30/2008 Physician United States
Primary
Secondary
Concomitant
Visual Acuity Reduced Other Serious 5/1/2008 Male 209 lb 6/10/2008 Consumer United States
Primary
Concomitant
White Blood Cell Count Increased Other Serious 10/17/2006 78 Male 199 lb 6/12/2008 Physician United States
Primary
Secondary
Concomitant
Urinary Tract Infection Other Serious 1/1/2003 70 Female 87 lb 7/3/2008 United States
Primary
Concomitant
Oedema Peripheral Other Serious 7/10/2008 Female 280 lb 7/25/2008 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 6/14/2008 Male 174 lb 7/28/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 7/31/2008 Consumer United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 8/1/2008 Consumer United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/7/2008 Consumer United States
Primary
Secondary
Concomitant
Mobility Decreased Hospitalization 2/1/2008 Female 208 lb 8/8/2008 Consumer United States
Primary
Concomitant
Gait Disturbance Hospitalization 6/14/2008 Male 174 lb 8/8/2008 Other Health Professional United States
Primary
Secondary
Concomitant
Thrombosis Hospitalization 4/1/2008 Female 275 lb 8/14/2008 Consumer United States
Primary
Secondary
Concomitant
Blood Glucose Increased Other Serious 5/16/2008 Female 149 lb 8/20/2008 Physician United States
Primary
Concomitant
Wound Secretion 1/1/1992 Female 148 lb 9/2/2008 Physician United States
Primary
Secondary
Concomitant
White Blood Cell Count Abnormal 4/1/2008 Female 9/2/2008 Pharmacist United States
Primary
Secondary
Concomitant
Thinking Abnormal Life Threatening 1/1/2002 Male 215 lb 9/15/2008 Consumer United States
Primary
Secondary
Concomitant
Suicidal Behaviour Other Serious 1/1/2001 50 Female 256 lb 9/24/2008 Physician United States
Primary
Concomitant
Toothache Other Serious 1/1/2005 Male 185 lb 10/1/2008 Physician United States
Primary
Concomitant
Medication Residue 2/1/2008 88 Male 10/8/2008 Other Health Professional United States
Primary
Concomitant
Urinary Tract Infection Other Serious 9/1/2008 Female 11/3/2008 Consumer United States
Primary
Concomitant
Vestibular Disorder Life Threatening 10/30/2008 Female 11/10/2008 Other Health Professional Italy
Primary
Secondary
Tardive Dyskinesia Other Serious 10/8/2002 10 Male 11/19/2008 United States
Primary
Concomitant
Urosepsis Other Serious 9/1/2008 Female 11/13/2008 Physician United States
Primary
Concomitant
Vestibular Disorder Life Threatening 10/30/2008 Female 11/28/2008 Other Health Professional Italy
Primary
Secondary
Intestinal Obstruction Death 2/5/2008 Male 184 lb 12/1/2008 United States
Primary
Concomitant
Troponin I Increased Hospitalization 1/30/2008 Female 213 lb 1/9/2009 Physician United States
Primary
Concomitant
Blood Creatine Phosphokinase Increased 48 Female 1/13/2009 Consumer United States
Primary
Concomitant
Diabetes Mellitus Death 1/1/1990 51 Male 204 lb 1/20/2009 Other Health Professional United States
Primary
Secondary
Concomitant
Convulsion Other Serious 61 Female 128 lb 1/28/2009 Consumer United States
Primary
Concomitant

Drug Data